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Gene Ontology Browser
Term Detail
GO term:chaperone-mediated protein folding
GO id:GO:0061077
Definition:The process of inhibiting aggregation and assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure that is dependent on interaction with a chaperone.
Number of paths to term: 5

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-acellular metabolic process
                                is-acellular macromolecule metabolic process
                                        is-acellular protein metabolic process
                                                is-aprotein folding
                                                        is-a'de novo' protein folding +
                                                        is-achaperone-mediated protein folding [GO:0061077] (46 genes, 54 annotations)
                                                                is-aATP-independent chaperone mediated protein folding
                                                                is-achaperone cofactor-dependent protein refolding
                                                                is-achaperone mediated protein folding independent of cofactor
                                                                is-achaperone mediated protein folding requiring cofactor
                                                        negatively-regulatesnegative regulation of protein folding +
                                                        positively-regulatespositive regulation of protein folding
                                                        is-apost-chaperonin tubulin folding pathway
                                                        is-aprotein folding in endoplasmic reticulum +
                                                        is-aprotein maturation by protein folding
                                                        is-aprotein refolding +
                                                        regulatesregulation of protein folding +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-acellular metabolic process
                                is-acellular macromolecule metabolic process
                                        is-acellular protein metabolic process
                                                is-aprotein folding
                                                        is-a'de novo' protein folding +
                                                        is-achaperone-mediated protein folding [GO:0061077] (46 genes, 54 annotations)
                                                                is-aATP-independent chaperone mediated protein folding
                                                                is-achaperone cofactor-dependent protein refolding
                                                                is-achaperone mediated protein folding independent of cofactor
                                                                is-achaperone mediated protein folding requiring cofactor
                                                        negatively-regulatesnegative regulation of protein folding +
                                                        positively-regulatespositive regulation of protein folding
                                                        is-apost-chaperonin tubulin folding pathway
                                                        is-aprotein folding in endoplasmic reticulum +
                                                        is-aprotein maturation by protein folding
                                                        is-aprotein refolding +
                                                        regulatesregulation of protein folding +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aorganic substance metabolic process
                                is-amacromolecule metabolic process
                                        is-acellular macromolecule metabolic process
                                                is-acellular protein metabolic process
                                                        is-aprotein folding
                                                                is-a'de novo' protein folding +
                                                                is-achaperone-mediated protein folding [GO:0061077] (46 genes, 54 annotations)
                                                                        is-aATP-independent chaperone mediated protein folding
                                                                        is-achaperone cofactor-dependent protein refolding
                                                                        is-achaperone mediated protein folding independent of cofactor
                                                                        is-achaperone mediated protein folding requiring cofactor
                                                                negatively-regulatesnegative regulation of protein folding +
                                                                positively-regulatespositive regulation of protein folding
                                                                is-apost-chaperonin tubulin folding pathway
                                                                is-aprotein folding in endoplasmic reticulum +
                                                                is-aprotein maturation by protein folding
                                                                is-aprotein refolding +
                                                                regulatesregulation of protein folding +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aorganic substance metabolic process
                                is-amacromolecule metabolic process
                                        is-aprotein metabolic process
                                                is-acellular protein metabolic process
                                                        is-aprotein folding
                                                                is-a'de novo' protein folding +
                                                                is-achaperone-mediated protein folding [GO:0061077] (46 genes, 54 annotations)
                                                                        is-aATP-independent chaperone mediated protein folding
                                                                        is-achaperone cofactor-dependent protein refolding
                                                                        is-achaperone mediated protein folding independent of cofactor
                                                                        is-achaperone mediated protein folding requiring cofactor
                                                                negatively-regulatesnegative regulation of protein folding +
                                                                positively-regulatespositive regulation of protein folding
                                                                is-apost-chaperonin tubulin folding pathway
                                                                is-aprotein folding in endoplasmic reticulum +
                                                                is-aprotein maturation by protein folding
                                                                is-aprotein refolding +
                                                                regulatesregulation of protein folding +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aprimary metabolic process
                                is-aprotein metabolic process
                                        is-acellular protein metabolic process
                                                is-aprotein folding
                                                        is-a'de novo' protein folding +
                                                        is-achaperone-mediated protein folding [GO:0061077] (46 genes, 54 annotations)
                                                                is-aATP-independent chaperone mediated protein folding
                                                                is-achaperone cofactor-dependent protein refolding
                                                                is-achaperone mediated protein folding independent of cofactor
                                                                is-achaperone mediated protein folding requiring cofactor
                                                        negatively-regulatesnegative regulation of protein folding +
                                                        positively-regulatespositive regulation of protein folding
                                                        is-apost-chaperonin tubulin folding pathway
                                                        is-aprotein folding in endoplasmic reticulum +
                                                        is-aprotein maturation by protein folding
                                                        is-aprotein refolding +
                                                        regulatesregulation of protein folding +


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/18/2014
MGI 5.20
The Jackson Laboratory