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Term Detail
GO term:ubiquitin-dependent ERAD pathway
Synonym: endoplasmic reticulum-associated ubiquitin-dependent protein catabolic process
Synonym: endoplasmic reticulum-associated ubiqutin-dependent protein catabolism
Synonym: ERAD
Synonym: ER-associated ubiquitin-dependent protein breakdown
Synonym: ER-associated ubiquitin-dependent protein catabolic process
Synonym: ER-associated ubiquitin-dependent protein catabolic process
Synonym: ER-associated ubiquitin-dependent protein catabolism
Synonym: ER-associated ubiquitin-dependent protein degradation
Synonym: ubiquitin-dependent proteasomal protein catabolism of ER proteins
GO id:GO:0030433
Definition:The series of steps necessary to target endoplasmic reticulum (ER)-resident proteins for degradation by the cytoplasmic proteasome. Begins with recognition of the ER-resident protein, includes retrotranslocation (dislocation) of the protein from the ER to the cytosol, protein ubiquitination necessary for correct substrate transfer, transport of the protein to the proteasome, and ends with degradation of the protein by the cytoplasmic proteasome.
CommentsSee also the biological process terms 'ERAD pathway ; GO:0036503', 'unfolded protein response ; GO:0030968' and 'retrograde protein transport, ER to cytosol ; GO:0030970'.
Number of paths to term: 70

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-acellular metabolic process
                                is-acellular catabolic process
                                        is-acellular macromolecule catabolic process
                                                is-acellular protein catabolic process
                                                        part-ofproteolysis involved in cellular protein catabolic process
                                                                is-amodification-dependent protein catabolic process
                                                                        is-aubiquitin-dependent protein catabolic process
                                                                                is-aproteasome-mediated ubiquitin-dependent protein catabolic process
                                                                                        is-aanaphase-promoting complex-dependent catabolic process +
                                                                                        is-amitochondria-associated ubiquitin-dependent protein catabolic process
                                                                                        negatively-regulatesnegative regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                        positively-regulatespositive regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                        part-ofprotein denaturation involved in proteasomal ubiquitin-dependent protein catabolic process
                                                                                        regulatesregulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                        is-aribosome-associated ubiquitin-dependent protein catabolic process
                                                                                        is-aSCF-dependent proteasomal ubiquitin-dependent protein catabolic process
                                                                                        is-atranscription factor catabolic process +
                                                                                        is-aubiquitin-dependent catabolism of misfolded proteins by cytoplasm-associated proteasome
                                                                                        is-aubiquitin-dependent catabolism of misfolded proteins by nucleus-associated proteasome +
                                                                                        is-aubiquitin-dependent ERAD pathway [GO:0030433] (66 genes, 93 annotations)
                                                                                                negatively-regulatesnegative regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                                positively-regulatespositive regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                                regulatesregulation of ER-associated ubiquitin-dependent protein catabolic process +
                                                                                                is-aubiquitin-dependent glycoprotein ERAD pathway +
                                                                                        is-aubiquitin-dependent protein catabolic process via the N-end rule pathway


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-acellular metabolic process
                                is-acellular catabolic process
                                        is-acellular macromolecule catabolic process
                                                is-acellular protein catabolic process
                                                        part-ofproteolysis involved in cellular protein catabolic process
                                                                is-aproteasomal protein catabolic process
                                                                        is-aproteasome-mediated ubiquitin-dependent protein catabolic process
                                                                                is-aanaphase-promoting complex-dependent catabolic process +
                                                                                is-amitochondria-associated ubiquitin-dependent protein catabolic process
                                                                                negatively-regulatesnegative regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                positively-regulatespositive regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                part-ofprotein denaturation involved in proteasomal ubiquitin-dependent protein catabolic process
                                                                                regulatesregulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                is-aribosome-associated ubiquitin-dependent protein catabolic process
                                                                                is-aSCF-dependent proteasomal ubiquitin-dependent protein catabolic process
                                                                                is-atranscription factor catabolic process +
                                                                                is-aubiquitin-dependent catabolism of misfolded proteins by cytoplasm-associated proteasome
                                                                                is-aubiquitin-dependent catabolism of misfolded proteins by nucleus-associated proteasome +
                                                                                is-aubiquitin-dependent ERAD pathway [GO:0030433] (66 genes, 93 annotations)
                                                                                        negatively-regulatesnegative regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                        positively-regulatespositive regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                        regulatesregulation of ER-associated ubiquitin-dependent protein catabolic process +
                                                                                        is-aubiquitin-dependent glycoprotein ERAD pathway +
                                                                                is-aubiquitin-dependent protein catabolic process via the N-end rule pathway


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-acellular metabolic process
                                is-acellular catabolic process
                                        is-acellular macromolecule catabolic process
                                                is-amodification-dependent macromolecule catabolic process
                                                        is-amodification-dependent protein catabolic process
                                                                is-aubiquitin-dependent protein catabolic process
                                                                        is-aproteasome-mediated ubiquitin-dependent protein catabolic process
                                                                                is-aanaphase-promoting complex-dependent catabolic process +
                                                                                is-amitochondria-associated ubiquitin-dependent protein catabolic process
                                                                                negatively-regulatesnegative regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                positively-regulatespositive regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                part-ofprotein denaturation involved in proteasomal ubiquitin-dependent protein catabolic process
                                                                                regulatesregulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                is-aribosome-associated ubiquitin-dependent protein catabolic process
                                                                                is-aSCF-dependent proteasomal ubiquitin-dependent protein catabolic process
                                                                                is-atranscription factor catabolic process +
                                                                                is-aubiquitin-dependent catabolism of misfolded proteins by cytoplasm-associated proteasome
                                                                                is-aubiquitin-dependent catabolism of misfolded proteins by nucleus-associated proteasome +
                                                                                is-aubiquitin-dependent ERAD pathway [GO:0030433] (66 genes, 93 annotations)
                                                                                        negatively-regulatesnegative regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                        positively-regulatespositive regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                        regulatesregulation of ER-associated ubiquitin-dependent protein catabolic process +
                                                                                        is-aubiquitin-dependent glycoprotein ERAD pathway +
                                                                                is-aubiquitin-dependent protein catabolic process via the N-end rule pathway


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-acellular metabolic process
                                is-acellular macromolecule metabolic process
                                        is-acellular macromolecule catabolic process
                                                is-acellular protein catabolic process
                                                        part-ofproteolysis involved in cellular protein catabolic process
                                                                is-amodification-dependent protein catabolic process
                                                                        is-aubiquitin-dependent protein catabolic process
                                                                                is-aproteasome-mediated ubiquitin-dependent protein catabolic process
                                                                                        is-aanaphase-promoting complex-dependent catabolic process +
                                                                                        is-amitochondria-associated ubiquitin-dependent protein catabolic process
                                                                                        negatively-regulatesnegative regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                        positively-regulatespositive regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                        part-ofprotein denaturation involved in proteasomal ubiquitin-dependent protein catabolic process
                                                                                        regulatesregulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                        is-aribosome-associated ubiquitin-dependent protein catabolic process
                                                                                        is-aSCF-dependent proteasomal ubiquitin-dependent protein catabolic process
                                                                                        is-atranscription factor catabolic process +
                                                                                        is-aubiquitin-dependent catabolism of misfolded proteins by cytoplasm-associated proteasome
                                                                                        is-aubiquitin-dependent catabolism of misfolded proteins by nucleus-associated proteasome +
                                                                                        is-aubiquitin-dependent ERAD pathway [GO:0030433] (66 genes, 93 annotations)
                                                                                                negatively-regulatesnegative regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                                positively-regulatespositive regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                                regulatesregulation of ER-associated ubiquitin-dependent protein catabolic process +
                                                                                                is-aubiquitin-dependent glycoprotein ERAD pathway +
                                                                                        is-aubiquitin-dependent protein catabolic process via the N-end rule pathway


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-acellular metabolic process
                                is-acellular macromolecule metabolic process
                                        is-acellular macromolecule catabolic process
                                                is-acellular protein catabolic process
                                                        part-ofproteolysis involved in cellular protein catabolic process
                                                                is-aproteasomal protein catabolic process
                                                                        is-aproteasome-mediated ubiquitin-dependent protein catabolic process
                                                                                is-aanaphase-promoting complex-dependent catabolic process +
                                                                                is-amitochondria-associated ubiquitin-dependent protein catabolic process
                                                                                negatively-regulatesnegative regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                positively-regulatespositive regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                part-ofprotein denaturation involved in proteasomal ubiquitin-dependent protein catabolic process
                                                                                regulatesregulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                is-aribosome-associated ubiquitin-dependent protein catabolic process
                                                                                is-aSCF-dependent proteasomal ubiquitin-dependent protein catabolic process
                                                                                is-atranscription factor catabolic process +
                                                                                is-aubiquitin-dependent catabolism of misfolded proteins by cytoplasm-associated proteasome
                                                                                is-aubiquitin-dependent catabolism of misfolded proteins by nucleus-associated proteasome +
                                                                                is-aubiquitin-dependent ERAD pathway [GO:0030433] (66 genes, 93 annotations)
                                                                                        negatively-regulatesnegative regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                        positively-regulatespositive regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                        regulatesregulation of ER-associated ubiquitin-dependent protein catabolic process +
                                                                                        is-aubiquitin-dependent glycoprotein ERAD pathway +
                                                                                is-aubiquitin-dependent protein catabolic process via the N-end rule pathway


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-acellular metabolic process
                                is-acellular macromolecule metabolic process
                                        is-acellular macromolecule catabolic process
                                                is-amodification-dependent macromolecule catabolic process
                                                        is-amodification-dependent protein catabolic process
                                                                is-aubiquitin-dependent protein catabolic process
                                                                        is-aproteasome-mediated ubiquitin-dependent protein catabolic process
                                                                                is-aanaphase-promoting complex-dependent catabolic process +
                                                                                is-amitochondria-associated ubiquitin-dependent protein catabolic process
                                                                                negatively-regulatesnegative regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                positively-regulatespositive regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                part-ofprotein denaturation involved in proteasomal ubiquitin-dependent protein catabolic process
                                                                                regulatesregulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                is-aribosome-associated ubiquitin-dependent protein catabolic process
                                                                                is-aSCF-dependent proteasomal ubiquitin-dependent protein catabolic process
                                                                                is-atranscription factor catabolic process +
                                                                                is-aubiquitin-dependent catabolism of misfolded proteins by cytoplasm-associated proteasome
                                                                                is-aubiquitin-dependent catabolism of misfolded proteins by nucleus-associated proteasome +
                                                                                is-aubiquitin-dependent ERAD pathway [GO:0030433] (66 genes, 93 annotations)
                                                                                        negatively-regulatesnegative regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                        positively-regulatespositive regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                        regulatesregulation of ER-associated ubiquitin-dependent protein catabolic process +
                                                                                        is-aubiquitin-dependent glycoprotein ERAD pathway +
                                                                                is-aubiquitin-dependent protein catabolic process via the N-end rule pathway


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-acellular metabolic process
                                is-acellular macromolecule metabolic process
                                        is-acellular protein metabolic process
                                                is-acellular protein catabolic process
                                                        part-ofproteolysis involved in cellular protein catabolic process
                                                                is-amodification-dependent protein catabolic process
                                                                        is-aubiquitin-dependent protein catabolic process
                                                                                is-aproteasome-mediated ubiquitin-dependent protein catabolic process
                                                                                        is-aanaphase-promoting complex-dependent catabolic process +
                                                                                        is-amitochondria-associated ubiquitin-dependent protein catabolic process
                                                                                        negatively-regulatesnegative regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                        positively-regulatespositive regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                        part-ofprotein denaturation involved in proteasomal ubiquitin-dependent protein catabolic process
                                                                                        regulatesregulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                        is-aribosome-associated ubiquitin-dependent protein catabolic process
                                                                                        is-aSCF-dependent proteasomal ubiquitin-dependent protein catabolic process
                                                                                        is-atranscription factor catabolic process +
                                                                                        is-aubiquitin-dependent catabolism of misfolded proteins by cytoplasm-associated proteasome
                                                                                        is-aubiquitin-dependent catabolism of misfolded proteins by nucleus-associated proteasome +
                                                                                        is-aubiquitin-dependent ERAD pathway [GO:0030433] (66 genes, 93 annotations)
                                                                                                negatively-regulatesnegative regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                                positively-regulatespositive regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                                regulatesregulation of ER-associated ubiquitin-dependent protein catabolic process +
                                                                                                is-aubiquitin-dependent glycoprotein ERAD pathway +
                                                                                        is-aubiquitin-dependent protein catabolic process via the N-end rule pathway


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-acellular metabolic process
                                is-acellular macromolecule metabolic process
                                        is-acellular protein metabolic process
                                                is-acellular protein catabolic process
                                                        part-ofproteolysis involved in cellular protein catabolic process
                                                                is-aproteasomal protein catabolic process
                                                                        is-aproteasome-mediated ubiquitin-dependent protein catabolic process
                                                                                is-aanaphase-promoting complex-dependent catabolic process +
                                                                                is-amitochondria-associated ubiquitin-dependent protein catabolic process
                                                                                negatively-regulatesnegative regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                positively-regulatespositive regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                part-ofprotein denaturation involved in proteasomal ubiquitin-dependent protein catabolic process
                                                                                regulatesregulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                is-aribosome-associated ubiquitin-dependent protein catabolic process
                                                                                is-aSCF-dependent proteasomal ubiquitin-dependent protein catabolic process
                                                                                is-atranscription factor catabolic process +
                                                                                is-aubiquitin-dependent catabolism of misfolded proteins by cytoplasm-associated proteasome
                                                                                is-aubiquitin-dependent catabolism of misfolded proteins by nucleus-associated proteasome +
                                                                                is-aubiquitin-dependent ERAD pathway [GO:0030433] (66 genes, 93 annotations)
                                                                                        negatively-regulatesnegative regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                        positively-regulatespositive regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                        regulatesregulation of ER-associated ubiquitin-dependent protein catabolic process +
                                                                                        is-aubiquitin-dependent glycoprotein ERAD pathway +
                                                                                is-aubiquitin-dependent protein catabolic process via the N-end rule pathway


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-acellular response to stimulus
                                is-acellular response to stress
                                        is-aresponse to endoplasmic reticulum stress
                                                is-aERAD pathway
                                                        is-aER-associated misfolded protein catabolic process
                                                        part-ofmaintenance of unfolded protein involved in ERAD pathway
                                                        negatively-regulatesnegative regulation of ERAD pathway +
                                                        positively-regulatespositive regulation of ERAD pathway +
                                                        part-ofprotein localization to cytosolic proteasome complex involved in ERAD pathway
                                                        regulatesregulation of ERAD pathway +
                                                        part-ofretrograde protein transport, ER to cytosol +
                                                        is-aubiquitin-dependent ERAD pathway [GO:0030433] (66 genes, 93 annotations)
                                                                negatively-regulatesnegative regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                positively-regulatespositive regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                regulatesregulation of ER-associated ubiquitin-dependent protein catabolic process +
                                                                is-aubiquitin-dependent glycoprotein ERAD pathway +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-aERAD pathway
                                        is-aER-associated misfolded protein catabolic process
                                        part-ofmaintenance of unfolded protein involved in ERAD pathway
                                        negatively-regulatesnegative regulation of ERAD pathway +
                                        positively-regulatespositive regulation of ERAD pathway +
                                        part-ofprotein localization to cytosolic proteasome complex involved in ERAD pathway
                                        regulatesregulation of ERAD pathway +
                                        part-ofretrograde protein transport, ER to cytosol +
                                        is-aubiquitin-dependent ERAD pathway [GO:0030433] (66 genes, 93 annotations)
                                                negatively-regulatesnegative regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                positively-regulatespositive regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                regulatesregulation of ER-associated ubiquitin-dependent protein catabolic process +
                                                is-aubiquitin-dependent glycoprotein ERAD pathway +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-acatabolic process
                                is-acellular catabolic process
                                        is-acellular macromolecule catabolic process
                                                is-acellular protein catabolic process
                                                        part-ofproteolysis involved in cellular protein catabolic process
                                                                is-amodification-dependent protein catabolic process
                                                                        is-aubiquitin-dependent protein catabolic process
                                                                                is-aproteasome-mediated ubiquitin-dependent protein catabolic process
                                                                                        is-aanaphase-promoting complex-dependent catabolic process +
                                                                                        is-amitochondria-associated ubiquitin-dependent protein catabolic process
                                                                                        negatively-regulatesnegative regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                        positively-regulatespositive regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                        part-ofprotein denaturation involved in proteasomal ubiquitin-dependent protein catabolic process
                                                                                        regulatesregulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                        is-aribosome-associated ubiquitin-dependent protein catabolic process
                                                                                        is-aSCF-dependent proteasomal ubiquitin-dependent protein catabolic process
                                                                                        is-atranscription factor catabolic process +
                                                                                        is-aubiquitin-dependent catabolism of misfolded proteins by cytoplasm-associated proteasome
                                                                                        is-aubiquitin-dependent catabolism of misfolded proteins by nucleus-associated proteasome +
                                                                                        is-aubiquitin-dependent ERAD pathway [GO:0030433] (66 genes, 93 annotations)
                                                                                                negatively-regulatesnegative regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                                positively-regulatespositive regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                                regulatesregulation of ER-associated ubiquitin-dependent protein catabolic process +
                                                                                                is-aubiquitin-dependent glycoprotein ERAD pathway +
                                                                                        is-aubiquitin-dependent protein catabolic process via the N-end rule pathway


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-acatabolic process
                                is-acellular catabolic process
                                        is-acellular macromolecule catabolic process
                                                is-acellular protein catabolic process
                                                        part-ofproteolysis involved in cellular protein catabolic process
                                                                is-aproteasomal protein catabolic process
                                                                        is-aproteasome-mediated ubiquitin-dependent protein catabolic process
                                                                                is-aanaphase-promoting complex-dependent catabolic process +
                                                                                is-amitochondria-associated ubiquitin-dependent protein catabolic process
                                                                                negatively-regulatesnegative regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                positively-regulatespositive regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                part-ofprotein denaturation involved in proteasomal ubiquitin-dependent protein catabolic process
                                                                                regulatesregulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                is-aribosome-associated ubiquitin-dependent protein catabolic process
                                                                                is-aSCF-dependent proteasomal ubiquitin-dependent protein catabolic process
                                                                                is-atranscription factor catabolic process +
                                                                                is-aubiquitin-dependent catabolism of misfolded proteins by cytoplasm-associated proteasome
                                                                                is-aubiquitin-dependent catabolism of misfolded proteins by nucleus-associated proteasome +
                                                                                is-aubiquitin-dependent ERAD pathway [GO:0030433] (66 genes, 93 annotations)
                                                                                        negatively-regulatesnegative regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                        positively-regulatespositive regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                        regulatesregulation of ER-associated ubiquitin-dependent protein catabolic process +
                                                                                        is-aubiquitin-dependent glycoprotein ERAD pathway +
                                                                                is-aubiquitin-dependent protein catabolic process via the N-end rule pathway


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-acatabolic process
                                is-acellular catabolic process
                                        is-acellular macromolecule catabolic process
                                                is-amodification-dependent macromolecule catabolic process
                                                        is-amodification-dependent protein catabolic process
                                                                is-aubiquitin-dependent protein catabolic process
                                                                        is-aproteasome-mediated ubiquitin-dependent protein catabolic process
                                                                                is-aanaphase-promoting complex-dependent catabolic process +
                                                                                is-amitochondria-associated ubiquitin-dependent protein catabolic process
                                                                                negatively-regulatesnegative regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                positively-regulatespositive regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                part-ofprotein denaturation involved in proteasomal ubiquitin-dependent protein catabolic process
                                                                                regulatesregulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                is-aribosome-associated ubiquitin-dependent protein catabolic process
                                                                                is-aSCF-dependent proteasomal ubiquitin-dependent protein catabolic process
                                                                                is-atranscription factor catabolic process +
                                                                                is-aubiquitin-dependent catabolism of misfolded proteins by cytoplasm-associated proteasome
                                                                                is-aubiquitin-dependent catabolism of misfolded proteins by nucleus-associated proteasome +
                                                                                is-aubiquitin-dependent ERAD pathway [GO:0030433] (66 genes, 93 annotations)
                                                                                        negatively-regulatesnegative regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                        positively-regulatespositive regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                        regulatesregulation of ER-associated ubiquitin-dependent protein catabolic process +
                                                                                        is-aubiquitin-dependent glycoprotein ERAD pathway +
                                                                                is-aubiquitin-dependent protein catabolic process via the N-end rule pathway


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-acatabolic process
                                is-aorganic substance catabolic process
                                        is-amacromolecule catabolic process
                                                is-acellular macromolecule catabolic process
                                                        is-acellular protein catabolic process
                                                                part-ofproteolysis involved in cellular protein catabolic process
                                                                        is-amodification-dependent protein catabolic process
                                                                                is-aubiquitin-dependent protein catabolic process
                                                                                        is-aproteasome-mediated ubiquitin-dependent protein catabolic process
                                                                                                is-aanaphase-promoting complex-dependent catabolic process +
                                                                                                is-amitochondria-associated ubiquitin-dependent protein catabolic process
                                                                                                negatively-regulatesnegative regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                                positively-regulatespositive regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                                part-ofprotein denaturation involved in proteasomal ubiquitin-dependent protein catabolic process
                                                                                                regulatesregulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                                is-aribosome-associated ubiquitin-dependent protein catabolic process
                                                                                                is-aSCF-dependent proteasomal ubiquitin-dependent protein catabolic process
                                                                                                is-atranscription factor catabolic process +
                                                                                                is-aubiquitin-dependent catabolism of misfolded proteins by cytoplasm-associated proteasome
                                                                                                is-aubiquitin-dependent catabolism of misfolded proteins by nucleus-associated proteasome +
                                                                                                is-aubiquitin-dependent ERAD pathway [GO:0030433] (66 genes, 93 annotations)
                                                                                                        negatively-regulatesnegative regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                                        positively-regulatespositive regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                                        regulatesregulation of ER-associated ubiquitin-dependent protein catabolic process +
                                                                                                        is-aubiquitin-dependent glycoprotein ERAD pathway +
                                                                                                is-aubiquitin-dependent protein catabolic process via the N-end rule pathway


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-acatabolic process
                                is-aorganic substance catabolic process
                                        is-amacromolecule catabolic process
                                                is-acellular macromolecule catabolic process
                                                        is-acellular protein catabolic process
                                                                part-ofproteolysis involved in cellular protein catabolic process
                                                                        is-aproteasomal protein catabolic process
                                                                                is-aproteasome-mediated ubiquitin-dependent protein catabolic process
                                                                                        is-aanaphase-promoting complex-dependent catabolic process +
                                                                                        is-amitochondria-associated ubiquitin-dependent protein catabolic process
                                                                                        negatively-regulatesnegative regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                        positively-regulatespositive regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                        part-ofprotein denaturation involved in proteasomal ubiquitin-dependent protein catabolic process
                                                                                        regulatesregulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                        is-aribosome-associated ubiquitin-dependent protein catabolic process
                                                                                        is-aSCF-dependent proteasomal ubiquitin-dependent protein catabolic process
                                                                                        is-atranscription factor catabolic process +
                                                                                        is-aubiquitin-dependent catabolism of misfolded proteins by cytoplasm-associated proteasome
                                                                                        is-aubiquitin-dependent catabolism of misfolded proteins by nucleus-associated proteasome +
                                                                                        is-aubiquitin-dependent ERAD pathway [GO:0030433] (66 genes, 93 annotations)
                                                                                                negatively-regulatesnegative regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                                positively-regulatespositive regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                                regulatesregulation of ER-associated ubiquitin-dependent protein catabolic process +
                                                                                                is-aubiquitin-dependent glycoprotein ERAD pathway +
                                                                                        is-aubiquitin-dependent protein catabolic process via the N-end rule pathway


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-acatabolic process
                                is-aorganic substance catabolic process
                                        is-amacromolecule catabolic process
                                                is-acellular macromolecule catabolic process
                                                        is-amodification-dependent macromolecule catabolic process
                                                                is-amodification-dependent protein catabolic process
                                                                        is-aubiquitin-dependent protein catabolic process
                                                                                is-aproteasome-mediated ubiquitin-dependent protein catabolic process
                                                                                        is-aanaphase-promoting complex-dependent catabolic process +
                                                                                        is-amitochondria-associated ubiquitin-dependent protein catabolic process
                                                                                        negatively-regulatesnegative regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                        positively-regulatespositive regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                        part-ofprotein denaturation involved in proteasomal ubiquitin-dependent protein catabolic process
                                                                                        regulatesregulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                        is-aribosome-associated ubiquitin-dependent protein catabolic process
                                                                                        is-aSCF-dependent proteasomal ubiquitin-dependent protein catabolic process
                                                                                        is-atranscription factor catabolic process +
                                                                                        is-aubiquitin-dependent catabolism of misfolded proteins by cytoplasm-associated proteasome
                                                                                        is-aubiquitin-dependent catabolism of misfolded proteins by nucleus-associated proteasome +
                                                                                        is-aubiquitin-dependent ERAD pathway [GO:0030433] (66 genes, 93 annotations)
                                                                                                negatively-regulatesnegative regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                                positively-regulatespositive regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                                regulatesregulation of ER-associated ubiquitin-dependent protein catabolic process +
                                                                                                is-aubiquitin-dependent glycoprotein ERAD pathway +
                                                                                        is-aubiquitin-dependent protein catabolic process via the N-end rule pathway


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-acatabolic process
                                is-aorganic substance catabolic process
                                        is-amacromolecule catabolic process
                                                is-aprotein catabolic process
                                                        is-acellular protein catabolic process
                                                                part-ofproteolysis involved in cellular protein catabolic process
                                                                        is-amodification-dependent protein catabolic process
                                                                                is-aubiquitin-dependent protein catabolic process
                                                                                        is-aproteasome-mediated ubiquitin-dependent protein catabolic process
                                                                                                is-aanaphase-promoting complex-dependent catabolic process +
                                                                                                is-amitochondria-associated ubiquitin-dependent protein catabolic process
                                                                                                negatively-regulatesnegative regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                                positively-regulatespositive regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                                part-ofprotein denaturation involved in proteasomal ubiquitin-dependent protein catabolic process
                                                                                                regulatesregulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                                is-aribosome-associated ubiquitin-dependent protein catabolic process
                                                                                                is-aSCF-dependent proteasomal ubiquitin-dependent protein catabolic process
                                                                                                is-atranscription factor catabolic process +
                                                                                                is-aubiquitin-dependent catabolism of misfolded proteins by cytoplasm-associated proteasome
                                                                                                is-aubiquitin-dependent catabolism of misfolded proteins by nucleus-associated proteasome +
                                                                                                is-aubiquitin-dependent ERAD pathway [GO:0030433] (66 genes, 93 annotations)
                                                                                                        negatively-regulatesnegative regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                                        positively-regulatespositive regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                                        regulatesregulation of ER-associated ubiquitin-dependent protein catabolic process +
                                                                                                        is-aubiquitin-dependent glycoprotein ERAD pathway +
                                                                                                is-aubiquitin-dependent protein catabolic process via the N-end rule pathway


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-acatabolic process
                                is-aorganic substance catabolic process
                                        is-amacromolecule catabolic process
                                                is-aprotein catabolic process
                                                        is-acellular protein catabolic process
                                                                part-ofproteolysis involved in cellular protein catabolic process
                                                                        is-aproteasomal protein catabolic process
                                                                                is-aproteasome-mediated ubiquitin-dependent protein catabolic process
                                                                                        is-aanaphase-promoting complex-dependent catabolic process +
                                                                                        is-amitochondria-associated ubiquitin-dependent protein catabolic process
                                                                                        negatively-regulatesnegative regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                        positively-regulatespositive regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                        part-ofprotein denaturation involved in proteasomal ubiquitin-dependent protein catabolic process
                                                                                        regulatesregulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                        is-aribosome-associated ubiquitin-dependent protein catabolic process
                                                                                        is-aSCF-dependent proteasomal ubiquitin-dependent protein catabolic process
                                                                                        is-atranscription factor catabolic process +
                                                                                        is-aubiquitin-dependent catabolism of misfolded proteins by cytoplasm-associated proteasome
                                                                                        is-aubiquitin-dependent catabolism of misfolded proteins by nucleus-associated proteasome +
                                                                                        is-aubiquitin-dependent ERAD pathway [GO:0030433] (66 genes, 93 annotations)
                                                                                                negatively-regulatesnegative regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                                positively-regulatespositive regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                                regulatesregulation of ER-associated ubiquitin-dependent protein catabolic process +
                                                                                                is-aubiquitin-dependent glycoprotein ERAD pathway +
                                                                                        is-aubiquitin-dependent protein catabolic process via the N-end rule pathway


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-acatabolic process
                                is-aorganic substance catabolic process
                                        is-amacromolecule catabolic process
                                                is-aprotein catabolic process
                                                        is-aERAD pathway
                                                                is-aER-associated misfolded protein catabolic process
                                                                part-ofmaintenance of unfolded protein involved in ERAD pathway
                                                                negatively-regulatesnegative regulation of ERAD pathway +
                                                                positively-regulatespositive regulation of ERAD pathway +
                                                                part-ofprotein localization to cytosolic proteasome complex involved in ERAD pathway
                                                                regulatesregulation of ERAD pathway +
                                                                part-ofretrograde protein transport, ER to cytosol +
                                                                is-aubiquitin-dependent ERAD pathway [GO:0030433] (66 genes, 93 annotations)
                                                                        negatively-regulatesnegative regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                        positively-regulatespositive regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                        regulatesregulation of ER-associated ubiquitin-dependent protein catabolic process +
                                                                        is-aubiquitin-dependent glycoprotein ERAD pathway +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-acatabolic process
                                is-aorganic substance catabolic process
                                        is-amacromolecule catabolic process
                                                is-aprotein catabolic process
                                                        is-aproteasomal protein catabolic process
                                                                is-aproteasome-mediated ubiquitin-dependent protein catabolic process
                                                                        is-aanaphase-promoting complex-dependent catabolic process +
                                                                        is-amitochondria-associated ubiquitin-dependent protein catabolic process
                                                                        negatively-regulatesnegative regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                        positively-regulatespositive regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                        part-ofprotein denaturation involved in proteasomal ubiquitin-dependent protein catabolic process
                                                                        regulatesregulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                        is-aribosome-associated ubiquitin-dependent protein catabolic process
                                                                        is-aSCF-dependent proteasomal ubiquitin-dependent protein catabolic process
                                                                        is-atranscription factor catabolic process +
                                                                        is-aubiquitin-dependent catabolism of misfolded proteins by cytoplasm-associated proteasome
                                                                        is-aubiquitin-dependent catabolism of misfolded proteins by nucleus-associated proteasome +
                                                                        is-aubiquitin-dependent ERAD pathway [GO:0030433] (66 genes, 93 annotations)
                                                                                negatively-regulatesnegative regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                positively-regulatespositive regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                regulatesregulation of ER-associated ubiquitin-dependent protein catabolic process +
                                                                                is-aubiquitin-dependent glycoprotein ERAD pathway +
                                                                        is-aubiquitin-dependent protein catabolic process via the N-end rule pathway


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-acatabolic process
                                is-asingle-organism catabolic process
                                        is-aERAD pathway
                                                is-aER-associated misfolded protein catabolic process
                                                part-ofmaintenance of unfolded protein involved in ERAD pathway
                                                negatively-regulatesnegative regulation of ERAD pathway +
                                                positively-regulatespositive regulation of ERAD pathway +
                                                part-ofprotein localization to cytosolic proteasome complex involved in ERAD pathway
                                                regulatesregulation of ERAD pathway +
                                                part-ofretrograde protein transport, ER to cytosol +
                                                is-aubiquitin-dependent ERAD pathway [GO:0030433] (66 genes, 93 annotations)
                                                        negatively-regulatesnegative regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                        positively-regulatespositive regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                        regulatesregulation of ER-associated ubiquitin-dependent protein catabolic process +
                                                        is-aubiquitin-dependent glycoprotein ERAD pathway +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-acellular metabolic process
                                is-acellular catabolic process
                                        is-acellular macromolecule catabolic process
                                                is-acellular protein catabolic process
                                                        part-ofproteolysis involved in cellular protein catabolic process
                                                                is-amodification-dependent protein catabolic process
                                                                        is-aubiquitin-dependent protein catabolic process
                                                                                is-aproteasome-mediated ubiquitin-dependent protein catabolic process
                                                                                        is-aanaphase-promoting complex-dependent catabolic process +
                                                                                        is-amitochondria-associated ubiquitin-dependent protein catabolic process
                                                                                        negatively-regulatesnegative regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                        positively-regulatespositive regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                        part-ofprotein denaturation involved in proteasomal ubiquitin-dependent protein catabolic process
                                                                                        regulatesregulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                        is-aribosome-associated ubiquitin-dependent protein catabolic process
                                                                                        is-aSCF-dependent proteasomal ubiquitin-dependent protein catabolic process
                                                                                        is-atranscription factor catabolic process +
                                                                                        is-aubiquitin-dependent catabolism of misfolded proteins by cytoplasm-associated proteasome
                                                                                        is-aubiquitin-dependent catabolism of misfolded proteins by nucleus-associated proteasome +
                                                                                        is-aubiquitin-dependent ERAD pathway [GO:0030433] (66 genes, 93 annotations)
                                                                                                negatively-regulatesnegative regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                                positively-regulatespositive regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                                regulatesregulation of ER-associated ubiquitin-dependent protein catabolic process +
                                                                                                is-aubiquitin-dependent glycoprotein ERAD pathway +
                                                                                        is-aubiquitin-dependent protein catabolic process via the N-end rule pathway


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-acellular metabolic process
                                is-acellular catabolic process
                                        is-acellular macromolecule catabolic process
                                                is-acellular protein catabolic process
                                                        part-ofproteolysis involved in cellular protein catabolic process
                                                                is-aproteasomal protein catabolic process
                                                                        is-aproteasome-mediated ubiquitin-dependent protein catabolic process
                                                                                is-aanaphase-promoting complex-dependent catabolic process +
                                                                                is-amitochondria-associated ubiquitin-dependent protein catabolic process
                                                                                negatively-regulatesnegative regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                positively-regulatespositive regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                part-ofprotein denaturation involved in proteasomal ubiquitin-dependent protein catabolic process
                                                                                regulatesregulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                is-aribosome-associated ubiquitin-dependent protein catabolic process
                                                                                is-aSCF-dependent proteasomal ubiquitin-dependent protein catabolic process
                                                                                is-atranscription factor catabolic process +
                                                                                is-aubiquitin-dependent catabolism of misfolded proteins by cytoplasm-associated proteasome
                                                                                is-aubiquitin-dependent catabolism of misfolded proteins by nucleus-associated proteasome +
                                                                                is-aubiquitin-dependent ERAD pathway [GO:0030433] (66 genes, 93 annotations)
                                                                                        negatively-regulatesnegative regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                        positively-regulatespositive regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                        regulatesregulation of ER-associated ubiquitin-dependent protein catabolic process +
                                                                                        is-aubiquitin-dependent glycoprotein ERAD pathway +
                                                                                is-aubiquitin-dependent protein catabolic process via the N-end rule pathway


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-acellular metabolic process
                                is-acellular catabolic process
                                        is-acellular macromolecule catabolic process
                                                is-amodification-dependent macromolecule catabolic process
                                                        is-amodification-dependent protein catabolic process
                                                                is-aubiquitin-dependent protein catabolic process
                                                                        is-aproteasome-mediated ubiquitin-dependent protein catabolic process
                                                                                is-aanaphase-promoting complex-dependent catabolic process +
                                                                                is-amitochondria-associated ubiquitin-dependent protein catabolic process
                                                                                negatively-regulatesnegative regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                positively-regulatespositive regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                part-ofprotein denaturation involved in proteasomal ubiquitin-dependent protein catabolic process
                                                                                regulatesregulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                is-aribosome-associated ubiquitin-dependent protein catabolic process
                                                                                is-aSCF-dependent proteasomal ubiquitin-dependent protein catabolic process
                                                                                is-atranscription factor catabolic process +
                                                                                is-aubiquitin-dependent catabolism of misfolded proteins by cytoplasm-associated proteasome
                                                                                is-aubiquitin-dependent catabolism of misfolded proteins by nucleus-associated proteasome +
                                                                                is-aubiquitin-dependent ERAD pathway [GO:0030433] (66 genes, 93 annotations)
                                                                                        negatively-regulatesnegative regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                        positively-regulatespositive regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                        regulatesregulation of ER-associated ubiquitin-dependent protein catabolic process +
                                                                                        is-aubiquitin-dependent glycoprotein ERAD pathway +
                                                                                is-aubiquitin-dependent protein catabolic process via the N-end rule pathway


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-acellular metabolic process
                                is-acellular macromolecule metabolic process
                                        is-acellular macromolecule catabolic process
                                                is-acellular protein catabolic process
                                                        part-ofproteolysis involved in cellular protein catabolic process
                                                                is-amodification-dependent protein catabolic process
                                                                        is-aubiquitin-dependent protein catabolic process
                                                                                is-aproteasome-mediated ubiquitin-dependent protein catabolic process
                                                                                        is-aanaphase-promoting complex-dependent catabolic process +
                                                                                        is-amitochondria-associated ubiquitin-dependent protein catabolic process
                                                                                        negatively-regulatesnegative regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                        positively-regulatespositive regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                        part-ofprotein denaturation involved in proteasomal ubiquitin-dependent protein catabolic process
                                                                                        regulatesregulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                        is-aribosome-associated ubiquitin-dependent protein catabolic process
                                                                                        is-aSCF-dependent proteasomal ubiquitin-dependent protein catabolic process
                                                                                        is-atranscription factor catabolic process +
                                                                                        is-aubiquitin-dependent catabolism of misfolded proteins by cytoplasm-associated proteasome
                                                                                        is-aubiquitin-dependent catabolism of misfolded proteins by nucleus-associated proteasome +
                                                                                        is-aubiquitin-dependent ERAD pathway [GO:0030433] (66 genes, 93 annotations)
                                                                                                negatively-regulatesnegative regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                                positively-regulatespositive regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                                regulatesregulation of ER-associated ubiquitin-dependent protein catabolic process +
                                                                                                is-aubiquitin-dependent glycoprotein ERAD pathway +
                                                                                        is-aubiquitin-dependent protein catabolic process via the N-end rule pathway


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-acellular metabolic process
                                is-acellular macromolecule metabolic process
                                        is-acellular macromolecule catabolic process
                                                is-acellular protein catabolic process
                                                        part-ofproteolysis involved in cellular protein catabolic process
                                                                is-aproteasomal protein catabolic process
                                                                        is-aproteasome-mediated ubiquitin-dependent protein catabolic process
                                                                                is-aanaphase-promoting complex-dependent catabolic process +
                                                                                is-amitochondria-associated ubiquitin-dependent protein catabolic process
                                                                                negatively-regulatesnegative regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                positively-regulatespositive regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                part-ofprotein denaturation involved in proteasomal ubiquitin-dependent protein catabolic process
                                                                                regulatesregulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                is-aribosome-associated ubiquitin-dependent protein catabolic process
                                                                                is-aSCF-dependent proteasomal ubiquitin-dependent protein catabolic process
                                                                                is-atranscription factor catabolic process +
                                                                                is-aubiquitin-dependent catabolism of misfolded proteins by cytoplasm-associated proteasome
                                                                                is-aubiquitin-dependent catabolism of misfolded proteins by nucleus-associated proteasome +
                                                                                is-aubiquitin-dependent ERAD pathway [GO:0030433] (66 genes, 93 annotations)
                                                                                        negatively-regulatesnegative regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                        positively-regulatespositive regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                        regulatesregulation of ER-associated ubiquitin-dependent protein catabolic process +
                                                                                        is-aubiquitin-dependent glycoprotein ERAD pathway +
                                                                                is-aubiquitin-dependent protein catabolic process via the N-end rule pathway


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-acellular metabolic process
                                is-acellular macromolecule metabolic process
                                        is-acellular macromolecule catabolic process
                                                is-amodification-dependent macromolecule catabolic process
                                                        is-amodification-dependent protein catabolic process
                                                                is-aubiquitin-dependent protein catabolic process
                                                                        is-aproteasome-mediated ubiquitin-dependent protein catabolic process
                                                                                is-aanaphase-promoting complex-dependent catabolic process +
                                                                                is-amitochondria-associated ubiquitin-dependent protein catabolic process
                                                                                negatively-regulatesnegative regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                positively-regulatespositive regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                part-ofprotein denaturation involved in proteasomal ubiquitin-dependent protein catabolic process
                                                                                regulatesregulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                is-aribosome-associated ubiquitin-dependent protein catabolic process
                                                                                is-aSCF-dependent proteasomal ubiquitin-dependent protein catabolic process
                                                                                is-atranscription factor catabolic process +
                                                                                is-aubiquitin-dependent catabolism of misfolded proteins by cytoplasm-associated proteasome
                                                                                is-aubiquitin-dependent catabolism of misfolded proteins by nucleus-associated proteasome +
                                                                                is-aubiquitin-dependent ERAD pathway [GO:0030433] (66 genes, 93 annotations)
                                                                                        negatively-regulatesnegative regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                        positively-regulatespositive regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                        regulatesregulation of ER-associated ubiquitin-dependent protein catabolic process +
                                                                                        is-aubiquitin-dependent glycoprotein ERAD pathway +
                                                                                is-aubiquitin-dependent protein catabolic process via the N-end rule pathway


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-acellular metabolic process
                                is-acellular macromolecule metabolic process
                                        is-acellular protein metabolic process
                                                is-acellular protein catabolic process
                                                        part-ofproteolysis involved in cellular protein catabolic process
                                                                is-amodification-dependent protein catabolic process
                                                                        is-aubiquitin-dependent protein catabolic process
                                                                                is-aproteasome-mediated ubiquitin-dependent protein catabolic process
                                                                                        is-aanaphase-promoting complex-dependent catabolic process +
                                                                                        is-amitochondria-associated ubiquitin-dependent protein catabolic process
                                                                                        negatively-regulatesnegative regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                        positively-regulatespositive regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                        part-ofprotein denaturation involved in proteasomal ubiquitin-dependent protein catabolic process
                                                                                        regulatesregulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                        is-aribosome-associated ubiquitin-dependent protein catabolic process
                                                                                        is-aSCF-dependent proteasomal ubiquitin-dependent protein catabolic process
                                                                                        is-atranscription factor catabolic process +
                                                                                        is-aubiquitin-dependent catabolism of misfolded proteins by cytoplasm-associated proteasome
                                                                                        is-aubiquitin-dependent catabolism of misfolded proteins by nucleus-associated proteasome +
                                                                                        is-aubiquitin-dependent ERAD pathway [GO:0030433] (66 genes, 93 annotations)
                                                                                                negatively-regulatesnegative regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                                positively-regulatespositive regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                                regulatesregulation of ER-associated ubiquitin-dependent protein catabolic process +
                                                                                                is-aubiquitin-dependent glycoprotein ERAD pathway +
                                                                                        is-aubiquitin-dependent protein catabolic process via the N-end rule pathway


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-acellular metabolic process
                                is-acellular macromolecule metabolic process
                                        is-acellular protein metabolic process
                                                is-acellular protein catabolic process
                                                        part-ofproteolysis involved in cellular protein catabolic process
                                                                is-aproteasomal protein catabolic process
                                                                        is-aproteasome-mediated ubiquitin-dependent protein catabolic process
                                                                                is-aanaphase-promoting complex-dependent catabolic process +
                                                                                is-amitochondria-associated ubiquitin-dependent protein catabolic process
                                                                                negatively-regulatesnegative regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                positively-regulatespositive regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                part-ofprotein denaturation involved in proteasomal ubiquitin-dependent protein catabolic process
                                                                                regulatesregulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                is-aribosome-associated ubiquitin-dependent protein catabolic process
                                                                                is-aSCF-dependent proteasomal ubiquitin-dependent protein catabolic process
                                                                                is-atranscription factor catabolic process +
                                                                                is-aubiquitin-dependent catabolism of misfolded proteins by cytoplasm-associated proteasome
                                                                                is-aubiquitin-dependent catabolism of misfolded proteins by nucleus-associated proteasome +
                                                                                is-aubiquitin-dependent ERAD pathway [GO:0030433] (66 genes, 93 annotations)
                                                                                        negatively-regulatesnegative regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                        positively-regulatespositive regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                        regulatesregulation of ER-associated ubiquitin-dependent protein catabolic process +
                                                                                        is-aubiquitin-dependent glycoprotein ERAD pathway +
                                                                                is-aubiquitin-dependent protein catabolic process via the N-end rule pathway


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aorganic substance metabolic process
                                is-amacromolecule metabolic process
                                        is-acellular macromolecule metabolic process
                                                is-acellular macromolecule catabolic process
                                                        is-acellular protein catabolic process
                                                                part-ofproteolysis involved in cellular protein catabolic process
                                                                        is-amodification-dependent protein catabolic process
                                                                                is-aubiquitin-dependent protein catabolic process
                                                                                        is-aproteasome-mediated ubiquitin-dependent protein catabolic process
                                                                                                is-aanaphase-promoting complex-dependent catabolic process +
                                                                                                is-amitochondria-associated ubiquitin-dependent protein catabolic process
                                                                                                negatively-regulatesnegative regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                                positively-regulatespositive regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                                part-ofprotein denaturation involved in proteasomal ubiquitin-dependent protein catabolic process
                                                                                                regulatesregulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                                is-aribosome-associated ubiquitin-dependent protein catabolic process
                                                                                                is-aSCF-dependent proteasomal ubiquitin-dependent protein catabolic process
                                                                                                is-atranscription factor catabolic process +
                                                                                                is-aubiquitin-dependent catabolism of misfolded proteins by cytoplasm-associated proteasome
                                                                                                is-aubiquitin-dependent catabolism of misfolded proteins by nucleus-associated proteasome +
                                                                                                is-aubiquitin-dependent ERAD pathway [GO:0030433] (66 genes, 93 annotations)
                                                                                                        negatively-regulatesnegative regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                                        positively-regulatespositive regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                                        regulatesregulation of ER-associated ubiquitin-dependent protein catabolic process +
                                                                                                        is-aubiquitin-dependent glycoprotein ERAD pathway +
                                                                                                is-aubiquitin-dependent protein catabolic process via the N-end rule pathway


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aorganic substance metabolic process
                                is-amacromolecule metabolic process
                                        is-acellular macromolecule metabolic process
                                                is-acellular macromolecule catabolic process
                                                        is-acellular protein catabolic process
                                                                part-ofproteolysis involved in cellular protein catabolic process
                                                                        is-aproteasomal protein catabolic process
                                                                                is-aproteasome-mediated ubiquitin-dependent protein catabolic process
                                                                                        is-aanaphase-promoting complex-dependent catabolic process +
                                                                                        is-amitochondria-associated ubiquitin-dependent protein catabolic process
                                                                                        negatively-regulatesnegative regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                        positively-regulatespositive regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                        part-ofprotein denaturation involved in proteasomal ubiquitin-dependent protein catabolic process
                                                                                        regulatesregulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                        is-aribosome-associated ubiquitin-dependent protein catabolic process
                                                                                        is-aSCF-dependent proteasomal ubiquitin-dependent protein catabolic process
                                                                                        is-atranscription factor catabolic process +
                                                                                        is-aubiquitin-dependent catabolism of misfolded proteins by cytoplasm-associated proteasome
                                                                                        is-aubiquitin-dependent catabolism of misfolded proteins by nucleus-associated proteasome +
                                                                                        is-aubiquitin-dependent ERAD pathway [GO:0030433] (66 genes, 93 annotations)
                                                                                                negatively-regulatesnegative regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                                positively-regulatespositive regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                                regulatesregulation of ER-associated ubiquitin-dependent protein catabolic process +
                                                                                                is-aubiquitin-dependent glycoprotein ERAD pathway +
                                                                                        is-aubiquitin-dependent protein catabolic process via the N-end rule pathway


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aorganic substance metabolic process
                                is-amacromolecule metabolic process
                                        is-acellular macromolecule metabolic process
                                                is-acellular macromolecule catabolic process
                                                        is-amodification-dependent macromolecule catabolic process
                                                                is-amodification-dependent protein catabolic process
                                                                        is-aubiquitin-dependent protein catabolic process
                                                                                is-aproteasome-mediated ubiquitin-dependent protein catabolic process
                                                                                        is-aanaphase-promoting complex-dependent catabolic process +
                                                                                        is-amitochondria-associated ubiquitin-dependent protein catabolic process
                                                                                        negatively-regulatesnegative regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                        positively-regulatespositive regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                        part-ofprotein denaturation involved in proteasomal ubiquitin-dependent protein catabolic process
                                                                                        regulatesregulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                        is-aribosome-associated ubiquitin-dependent protein catabolic process
                                                                                        is-aSCF-dependent proteasomal ubiquitin-dependent protein catabolic process
                                                                                        is-atranscription factor catabolic process +
                                                                                        is-aubiquitin-dependent catabolism of misfolded proteins by cytoplasm-associated proteasome
                                                                                        is-aubiquitin-dependent catabolism of misfolded proteins by nucleus-associated proteasome +
                                                                                        is-aubiquitin-dependent ERAD pathway [GO:0030433] (66 genes, 93 annotations)
                                                                                                negatively-regulatesnegative regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                                positively-regulatespositive regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                                regulatesregulation of ER-associated ubiquitin-dependent protein catabolic process +
                                                                                                is-aubiquitin-dependent glycoprotein ERAD pathway +
                                                                                        is-aubiquitin-dependent protein catabolic process via the N-end rule pathway


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aorganic substance metabolic process
                                is-amacromolecule metabolic process
                                        is-acellular macromolecule metabolic process
                                                is-acellular protein metabolic process
                                                        is-acellular protein catabolic process
                                                                part-ofproteolysis involved in cellular protein catabolic process
                                                                        is-amodification-dependent protein catabolic process
                                                                                is-aubiquitin-dependent protein catabolic process
                                                                                        is-aproteasome-mediated ubiquitin-dependent protein catabolic process
                                                                                                is-aanaphase-promoting complex-dependent catabolic process +
                                                                                                is-amitochondria-associated ubiquitin-dependent protein catabolic process
                                                                                                negatively-regulatesnegative regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                                positively-regulatespositive regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                                part-ofprotein denaturation involved in proteasomal ubiquitin-dependent protein catabolic process
                                                                                                regulatesregulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                                is-aribosome-associated ubiquitin-dependent protein catabolic process
                                                                                                is-aSCF-dependent proteasomal ubiquitin-dependent protein catabolic process
                                                                                                is-atranscription factor catabolic process +
                                                                                                is-aubiquitin-dependent catabolism of misfolded proteins by cytoplasm-associated proteasome
                                                                                                is-aubiquitin-dependent catabolism of misfolded proteins by nucleus-associated proteasome +
                                                                                                is-aubiquitin-dependent ERAD pathway [GO:0030433] (66 genes, 93 annotations)
                                                                                                        negatively-regulatesnegative regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                                        positively-regulatespositive regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                                        regulatesregulation of ER-associated ubiquitin-dependent protein catabolic process +
                                                                                                        is-aubiquitin-dependent glycoprotein ERAD pathway +
                                                                                                is-aubiquitin-dependent protein catabolic process via the N-end rule pathway


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aorganic substance metabolic process
                                is-amacromolecule metabolic process
                                        is-acellular macromolecule metabolic process
                                                is-acellular protein metabolic process
                                                        is-acellular protein catabolic process
                                                                part-ofproteolysis involved in cellular protein catabolic process
                                                                        is-aproteasomal protein catabolic process
                                                                                is-aproteasome-mediated ubiquitin-dependent protein catabolic process
                                                                                        is-aanaphase-promoting complex-dependent catabolic process +
                                                                                        is-amitochondria-associated ubiquitin-dependent protein catabolic process
                                                                                        negatively-regulatesnegative regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                        positively-regulatespositive regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                        part-ofprotein denaturation involved in proteasomal ubiquitin-dependent protein catabolic process
                                                                                        regulatesregulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                        is-aribosome-associated ubiquitin-dependent protein catabolic process
                                                                                        is-aSCF-dependent proteasomal ubiquitin-dependent protein catabolic process
                                                                                        is-atranscription factor catabolic process +
                                                                                        is-aubiquitin-dependent catabolism of misfolded proteins by cytoplasm-associated proteasome
                                                                                        is-aubiquitin-dependent catabolism of misfolded proteins by nucleus-associated proteasome +
                                                                                        is-aubiquitin-dependent ERAD pathway [GO:0030433] (66 genes, 93 annotations)
                                                                                                negatively-regulatesnegative regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                                positively-regulatespositive regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                                regulatesregulation of ER-associated ubiquitin-dependent protein catabolic process +
                                                                                                is-aubiquitin-dependent glycoprotein ERAD pathway +
                                                                                        is-aubiquitin-dependent protein catabolic process via the N-end rule pathway


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aorganic substance metabolic process
                                is-amacromolecule metabolic process
                                        is-amacromolecule catabolic process
                                                is-acellular macromolecule catabolic process
                                                        is-acellular protein catabolic process
                                                                part-ofproteolysis involved in cellular protein catabolic process
                                                                        is-amodification-dependent protein catabolic process
                                                                                is-aubiquitin-dependent protein catabolic process
                                                                                        is-aproteasome-mediated ubiquitin-dependent protein catabolic process
                                                                                                is-aanaphase-promoting complex-dependent catabolic process +
                                                                                                is-amitochondria-associated ubiquitin-dependent protein catabolic process
                                                                                                negatively-regulatesnegative regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                                positively-regulatespositive regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                                part-ofprotein denaturation involved in proteasomal ubiquitin-dependent protein catabolic process
                                                                                                regulatesregulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                                is-aribosome-associated ubiquitin-dependent protein catabolic process
                                                                                                is-aSCF-dependent proteasomal ubiquitin-dependent protein catabolic process
                                                                                                is-atranscription factor catabolic process +
                                                                                                is-aubiquitin-dependent catabolism of misfolded proteins by cytoplasm-associated proteasome
                                                                                                is-aubiquitin-dependent catabolism of misfolded proteins by nucleus-associated proteasome +
                                                                                                is-aubiquitin-dependent ERAD pathway [GO:0030433] (66 genes, 93 annotations)
                                                                                                        negatively-regulatesnegative regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                                        positively-regulatespositive regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                                        regulatesregulation of ER-associated ubiquitin-dependent protein catabolic process +
                                                                                                        is-aubiquitin-dependent glycoprotein ERAD pathway +
                                                                                                is-aubiquitin-dependent protein catabolic process via the N-end rule pathway


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aorganic substance metabolic process
                                is-amacromolecule metabolic process
                                        is-amacromolecule catabolic process
                                                is-acellular macromolecule catabolic process
                                                        is-acellular protein catabolic process
                                                                part-ofproteolysis involved in cellular protein catabolic process
                                                                        is-aproteasomal protein catabolic process
                                                                                is-aproteasome-mediated ubiquitin-dependent protein catabolic process
                                                                                        is-aanaphase-promoting complex-dependent catabolic process +
                                                                                        is-amitochondria-associated ubiquitin-dependent protein catabolic process
                                                                                        negatively-regulatesnegative regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                        positively-regulatespositive regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                        part-ofprotein denaturation involved in proteasomal ubiquitin-dependent protein catabolic process
                                                                                        regulatesregulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                        is-aribosome-associated ubiquitin-dependent protein catabolic process
                                                                                        is-aSCF-dependent proteasomal ubiquitin-dependent protein catabolic process
                                                                                        is-atranscription factor catabolic process +
                                                                                        is-aubiquitin-dependent catabolism of misfolded proteins by cytoplasm-associated proteasome
                                                                                        is-aubiquitin-dependent catabolism of misfolded proteins by nucleus-associated proteasome +
                                                                                        is-aubiquitin-dependent ERAD pathway [GO:0030433] (66 genes, 93 annotations)
                                                                                                negatively-regulatesnegative regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                                positively-regulatespositive regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                                regulatesregulation of ER-associated ubiquitin-dependent protein catabolic process +
                                                                                                is-aubiquitin-dependent glycoprotein ERAD pathway +
                                                                                        is-aubiquitin-dependent protein catabolic process via the N-end rule pathway


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aorganic substance metabolic process
                                is-amacromolecule metabolic process
                                        is-amacromolecule catabolic process
                                                is-acellular macromolecule catabolic process
                                                        is-amodification-dependent macromolecule catabolic process
                                                                is-amodification-dependent protein catabolic process
                                                                        is-aubiquitin-dependent protein catabolic process
                                                                                is-aproteasome-mediated ubiquitin-dependent protein catabolic process
                                                                                        is-aanaphase-promoting complex-dependent catabolic process +
                                                                                        is-amitochondria-associated ubiquitin-dependent protein catabolic process
                                                                                        negatively-regulatesnegative regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                        positively-regulatespositive regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                        part-ofprotein denaturation involved in proteasomal ubiquitin-dependent protein catabolic process
                                                                                        regulatesregulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                        is-aribosome-associated ubiquitin-dependent protein catabolic process
                                                                                        is-aSCF-dependent proteasomal ubiquitin-dependent protein catabolic process
                                                                                        is-atranscription factor catabolic process +
                                                                                        is-aubiquitin-dependent catabolism of misfolded proteins by cytoplasm-associated proteasome
                                                                                        is-aubiquitin-dependent catabolism of misfolded proteins by nucleus-associated proteasome +
                                                                                        is-aubiquitin-dependent ERAD pathway [GO:0030433] (66 genes, 93 annotations)
                                                                                                negatively-regulatesnegative regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                                positively-regulatespositive regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                                regulatesregulation of ER-associated ubiquitin-dependent protein catabolic process +
                                                                                                is-aubiquitin-dependent glycoprotein ERAD pathway +
                                                                                        is-aubiquitin-dependent protein catabolic process via the N-end rule pathway


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aorganic substance metabolic process
                                is-amacromolecule metabolic process
                                        is-amacromolecule catabolic process
                                                is-aprotein catabolic process
                                                        is-acellular protein catabolic process
                                                                part-ofproteolysis involved in cellular protein catabolic process
                                                                        is-amodification-dependent protein catabolic process
                                                                                is-aubiquitin-dependent protein catabolic process
                                                                                        is-aproteasome-mediated ubiquitin-dependent protein catabolic process
                                                                                                is-aanaphase-promoting complex-dependent catabolic process +
                                                                                                is-amitochondria-associated ubiquitin-dependent protein catabolic process
                                                                                                negatively-regulatesnegative regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                                positively-regulatespositive regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                                part-ofprotein denaturation involved in proteasomal ubiquitin-dependent protein catabolic process
                                                                                                regulatesregulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                                is-aribosome-associated ubiquitin-dependent protein catabolic process
                                                                                                is-aSCF-dependent proteasomal ubiquitin-dependent protein catabolic process
                                                                                                is-atranscription factor catabolic process +
                                                                                                is-aubiquitin-dependent catabolism of misfolded proteins by cytoplasm-associated proteasome
                                                                                                is-aubiquitin-dependent catabolism of misfolded proteins by nucleus-associated proteasome +
                                                                                                is-aubiquitin-dependent ERAD pathway [GO:0030433] (66 genes, 93 annotations)
                                                                                                        negatively-regulatesnegative regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                                        positively-regulatespositive regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                                        regulatesregulation of ER-associated ubiquitin-dependent protein catabolic process +
                                                                                                        is-aubiquitin-dependent glycoprotein ERAD pathway +
                                                                                                is-aubiquitin-dependent protein catabolic process via the N-end rule pathway


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aorganic substance metabolic process
                                is-amacromolecule metabolic process
                                        is-amacromolecule catabolic process
                                                is-aprotein catabolic process
                                                        is-acellular protein catabolic process
                                                                part-ofproteolysis involved in cellular protein catabolic process
                                                                        is-aproteasomal protein catabolic process
                                                                                is-aproteasome-mediated ubiquitin-dependent protein catabolic process
                                                                                        is-aanaphase-promoting complex-dependent catabolic process +
                                                                                        is-amitochondria-associated ubiquitin-dependent protein catabolic process
                                                                                        negatively-regulatesnegative regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                        positively-regulatespositive regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                        part-ofprotein denaturation involved in proteasomal ubiquitin-dependent protein catabolic process
                                                                                        regulatesregulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                        is-aribosome-associated ubiquitin-dependent protein catabolic process
                                                                                        is-aSCF-dependent proteasomal ubiquitin-dependent protein catabolic process
                                                                                        is-atranscription factor catabolic process +
                                                                                        is-aubiquitin-dependent catabolism of misfolded proteins by cytoplasm-associated proteasome
                                                                                        is-aubiquitin-dependent catabolism of misfolded proteins by nucleus-associated proteasome +
                                                                                        is-aubiquitin-dependent ERAD pathway [GO:0030433] (66 genes, 93 annotations)
                                                                                                negatively-regulatesnegative regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                                positively-regulatespositive regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                                regulatesregulation of ER-associated ubiquitin-dependent protein catabolic process +
                                                                                                is-aubiquitin-dependent glycoprotein ERAD pathway +
                                                                                        is-aubiquitin-dependent protein catabolic process via the N-end rule pathway


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aorganic substance metabolic process
                                is-amacromolecule metabolic process
                                        is-amacromolecule catabolic process
                                                is-aprotein catabolic process
                                                        is-aERAD pathway
                                                                is-aER-associated misfolded protein catabolic process
                                                                part-ofmaintenance of unfolded protein involved in ERAD pathway
                                                                negatively-regulatesnegative regulation of ERAD pathway +
                                                                positively-regulatespositive regulation of ERAD pathway +
                                                                part-ofprotein localization to cytosolic proteasome complex involved in ERAD pathway
                                                                regulatesregulation of ERAD pathway +
                                                                part-ofretrograde protein transport, ER to cytosol +
                                                                is-aubiquitin-dependent ERAD pathway [GO:0030433] (66 genes, 93 annotations)
                                                                        negatively-regulatesnegative regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                        positively-regulatespositive regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                        regulatesregulation of ER-associated ubiquitin-dependent protein catabolic process +
                                                                        is-aubiquitin-dependent glycoprotein ERAD pathway +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aorganic substance metabolic process
                                is-amacromolecule metabolic process
                                        is-amacromolecule catabolic process
                                                is-aprotein catabolic process
                                                        is-aproteasomal protein catabolic process
                                                                is-aproteasome-mediated ubiquitin-dependent protein catabolic process
                                                                        is-aanaphase-promoting complex-dependent catabolic process +
                                                                        is-amitochondria-associated ubiquitin-dependent protein catabolic process
                                                                        negatively-regulatesnegative regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                        positively-regulatespositive regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                        part-ofprotein denaturation involved in proteasomal ubiquitin-dependent protein catabolic process
                                                                        regulatesregulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                        is-aribosome-associated ubiquitin-dependent protein catabolic process
                                                                        is-aSCF-dependent proteasomal ubiquitin-dependent protein catabolic process
                                                                        is-atranscription factor catabolic process +
                                                                        is-aubiquitin-dependent catabolism of misfolded proteins by cytoplasm-associated proteasome
                                                                        is-aubiquitin-dependent catabolism of misfolded proteins by nucleus-associated proteasome +
                                                                        is-aubiquitin-dependent ERAD pathway [GO:0030433] (66 genes, 93 annotations)
                                                                                negatively-regulatesnegative regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                positively-regulatespositive regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                regulatesregulation of ER-associated ubiquitin-dependent protein catabolic process +
                                                                                is-aubiquitin-dependent glycoprotein ERAD pathway +
                                                                        is-aubiquitin-dependent protein catabolic process via the N-end rule pathway


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aorganic substance metabolic process
                                is-amacromolecule metabolic process
                                        is-aprotein metabolic process
                                                is-acellular protein metabolic process
                                                        is-acellular protein catabolic process
                                                                part-ofproteolysis involved in cellular protein catabolic process
                                                                        is-amodification-dependent protein catabolic process
                                                                                is-aubiquitin-dependent protein catabolic process
                                                                                        is-aproteasome-mediated ubiquitin-dependent protein catabolic process
                                                                                                is-aanaphase-promoting complex-dependent catabolic process +
                                                                                                is-amitochondria-associated ubiquitin-dependent protein catabolic process
                                                                                                negatively-regulatesnegative regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                                positively-regulatespositive regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                                part-ofprotein denaturation involved in proteasomal ubiquitin-dependent protein catabolic process
                                                                                                regulatesregulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                                is-aribosome-associated ubiquitin-dependent protein catabolic process
                                                                                                is-aSCF-dependent proteasomal ubiquitin-dependent protein catabolic process
                                                                                                is-atranscription factor catabolic process +
                                                                                                is-aubiquitin-dependent catabolism of misfolded proteins by cytoplasm-associated proteasome
                                                                                                is-aubiquitin-dependent catabolism of misfolded proteins by nucleus-associated proteasome +
                                                                                                is-aubiquitin-dependent ERAD pathway [GO:0030433] (66 genes, 93 annotations)
                                                                                                        negatively-regulatesnegative regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                                        positively-regulatespositive regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                                        regulatesregulation of ER-associated ubiquitin-dependent protein catabolic process +
                                                                                                        is-aubiquitin-dependent glycoprotein ERAD pathway +
                                                                                                is-aubiquitin-dependent protein catabolic process via the N-end rule pathway


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aorganic substance metabolic process
                                is-amacromolecule metabolic process
                                        is-aprotein metabolic process
                                                is-acellular protein metabolic process
                                                        is-acellular protein catabolic process
                                                                part-ofproteolysis involved in cellular protein catabolic process
                                                                        is-aproteasomal protein catabolic process
                                                                                is-aproteasome-mediated ubiquitin-dependent protein catabolic process
                                                                                        is-aanaphase-promoting complex-dependent catabolic process +
                                                                                        is-amitochondria-associated ubiquitin-dependent protein catabolic process
                                                                                        negatively-regulatesnegative regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                        positively-regulatespositive regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                        part-ofprotein denaturation involved in proteasomal ubiquitin-dependent protein catabolic process
                                                                                        regulatesregulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                        is-aribosome-associated ubiquitin-dependent protein catabolic process
                                                                                        is-aSCF-dependent proteasomal ubiquitin-dependent protein catabolic process
                                                                                        is-atranscription factor catabolic process +
                                                                                        is-aubiquitin-dependent catabolism of misfolded proteins by cytoplasm-associated proteasome
                                                                                        is-aubiquitin-dependent catabolism of misfolded proteins by nucleus-associated proteasome +
                                                                                        is-aubiquitin-dependent ERAD pathway [GO:0030433] (66 genes, 93 annotations)
                                                                                                negatively-regulatesnegative regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                                positively-regulatespositive regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                                regulatesregulation of ER-associated ubiquitin-dependent protein catabolic process +
                                                                                                is-aubiquitin-dependent glycoprotein ERAD pathway +
                                                                                        is-aubiquitin-dependent protein catabolic process via the N-end rule pathway


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aorganic substance metabolic process
                                is-amacromolecule metabolic process
                                        is-aprotein metabolic process
                                                is-aprotein catabolic process
                                                        is-acellular protein catabolic process
                                                                part-ofproteolysis involved in cellular protein catabolic process
                                                                        is-amodification-dependent protein catabolic process
                                                                                is-aubiquitin-dependent protein catabolic process
                                                                                        is-aproteasome-mediated ubiquitin-dependent protein catabolic process
                                                                                                is-aanaphase-promoting complex-dependent catabolic process +
                                                                                                is-amitochondria-associated ubiquitin-dependent protein catabolic process
                                                                                                negatively-regulatesnegative regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                                positively-regulatespositive regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                                part-ofprotein denaturation involved in proteasomal ubiquitin-dependent protein catabolic process
                                                                                                regulatesregulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                                is-aribosome-associated ubiquitin-dependent protein catabolic process
                                                                                                is-aSCF-dependent proteasomal ubiquitin-dependent protein catabolic process
                                                                                                is-atranscription factor catabolic process +
                                                                                                is-aubiquitin-dependent catabolism of misfolded proteins by cytoplasm-associated proteasome
                                                                                                is-aubiquitin-dependent catabolism of misfolded proteins by nucleus-associated proteasome +
                                                                                                is-aubiquitin-dependent ERAD pathway [GO:0030433] (66 genes, 93 annotations)
                                                                                                        negatively-regulatesnegative regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                                        positively-regulatespositive regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                                        regulatesregulation of ER-associated ubiquitin-dependent protein catabolic process +
                                                                                                        is-aubiquitin-dependent glycoprotein ERAD pathway +
                                                                                                is-aubiquitin-dependent protein catabolic process via the N-end rule pathway


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aorganic substance metabolic process
                                is-amacromolecule metabolic process
                                        is-aprotein metabolic process
                                                is-aprotein catabolic process
                                                        is-acellular protein catabolic process
                                                                part-ofproteolysis involved in cellular protein catabolic process
                                                                        is-aproteasomal protein catabolic process
                                                                                is-aproteasome-mediated ubiquitin-dependent protein catabolic process
                                                                                        is-aanaphase-promoting complex-dependent catabolic process +
                                                                                        is-amitochondria-associated ubiquitin-dependent protein catabolic process
                                                                                        negatively-regulatesnegative regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                        positively-regulatespositive regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                        part-ofprotein denaturation involved in proteasomal ubiquitin-dependent protein catabolic process
                                                                                        regulatesregulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                        is-aribosome-associated ubiquitin-dependent protein catabolic process
                                                                                        is-aSCF-dependent proteasomal ubiquitin-dependent protein catabolic process
                                                                                        is-atranscription factor catabolic process +
                                                                                        is-aubiquitin-dependent catabolism of misfolded proteins by cytoplasm-associated proteasome
                                                                                        is-aubiquitin-dependent catabolism of misfolded proteins by nucleus-associated proteasome +
                                                                                        is-aubiquitin-dependent ERAD pathway [GO:0030433] (66 genes, 93 annotations)
                                                                                                negatively-regulatesnegative regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                                positively-regulatespositive regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                                regulatesregulation of ER-associated ubiquitin-dependent protein catabolic process +
                                                                                                is-aubiquitin-dependent glycoprotein ERAD pathway +
                                                                                        is-aubiquitin-dependent protein catabolic process via the N-end rule pathway


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aorganic substance metabolic process
                                is-amacromolecule metabolic process
                                        is-aprotein metabolic process
                                                is-aprotein catabolic process
                                                        is-aERAD pathway
                                                                is-aER-associated misfolded protein catabolic process
                                                                part-ofmaintenance of unfolded protein involved in ERAD pathway
                                                                negatively-regulatesnegative regulation of ERAD pathway +
                                                                positively-regulatespositive regulation of ERAD pathway +
                                                                part-ofprotein localization to cytosolic proteasome complex involved in ERAD pathway
                                                                regulatesregulation of ERAD pathway +
                                                                part-ofretrograde protein transport, ER to cytosol +
                                                                is-aubiquitin-dependent ERAD pathway [GO:0030433] (66 genes, 93 annotations)
                                                                        negatively-regulatesnegative regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                        positively-regulatespositive regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                        regulatesregulation of ER-associated ubiquitin-dependent protein catabolic process +
                                                                        is-aubiquitin-dependent glycoprotein ERAD pathway +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aorganic substance metabolic process
                                is-amacromolecule metabolic process
                                        is-aprotein metabolic process
                                                is-aprotein catabolic process
                                                        is-aproteasomal protein catabolic process
                                                                is-aproteasome-mediated ubiquitin-dependent protein catabolic process
                                                                        is-aanaphase-promoting complex-dependent catabolic process +
                                                                        is-amitochondria-associated ubiquitin-dependent protein catabolic process
                                                                        negatively-regulatesnegative regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                        positively-regulatespositive regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                        part-ofprotein denaturation involved in proteasomal ubiquitin-dependent protein catabolic process
                                                                        regulatesregulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                        is-aribosome-associated ubiquitin-dependent protein catabolic process
                                                                        is-aSCF-dependent proteasomal ubiquitin-dependent protein catabolic process
                                                                        is-atranscription factor catabolic process +
                                                                        is-aubiquitin-dependent catabolism of misfolded proteins by cytoplasm-associated proteasome
                                                                        is-aubiquitin-dependent catabolism of misfolded proteins by nucleus-associated proteasome +
                                                                        is-aubiquitin-dependent ERAD pathway [GO:0030433] (66 genes, 93 annotations)
                                                                                negatively-regulatesnegative regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                positively-regulatespositive regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                regulatesregulation of ER-associated ubiquitin-dependent protein catabolic process +
                                                                                is-aubiquitin-dependent glycoprotein ERAD pathway +
                                                                        is-aubiquitin-dependent protein catabolic process via the N-end rule pathway


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aorganic substance metabolic process
                                is-amacromolecule metabolic process
                                        is-aprotein metabolic process
                                                is-aproteolysis
                                                        is-aproteolysis involved in cellular protein catabolic process
                                                                is-amodification-dependent protein catabolic process
                                                                        is-aubiquitin-dependent protein catabolic process
                                                                                is-aproteasome-mediated ubiquitin-dependent protein catabolic process
                                                                                        is-aanaphase-promoting complex-dependent catabolic process +
                                                                                        is-amitochondria-associated ubiquitin-dependent protein catabolic process
                                                                                        negatively-regulatesnegative regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                        positively-regulatespositive regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                        part-ofprotein denaturation involved in proteasomal ubiquitin-dependent protein catabolic process
                                                                                        regulatesregulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                        is-aribosome-associated ubiquitin-dependent protein catabolic process
                                                                                        is-aSCF-dependent proteasomal ubiquitin-dependent protein catabolic process
                                                                                        is-atranscription factor catabolic process +
                                                                                        is-aubiquitin-dependent catabolism of misfolded proteins by cytoplasm-associated proteasome
                                                                                        is-aubiquitin-dependent catabolism of misfolded proteins by nucleus-associated proteasome +
                                                                                        is-aubiquitin-dependent ERAD pathway [GO:0030433] (66 genes, 93 annotations)
                                                                                                negatively-regulatesnegative regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                                positively-regulatespositive regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                                regulatesregulation of ER-associated ubiquitin-dependent protein catabolic process +
                                                                                                is-aubiquitin-dependent glycoprotein ERAD pathway +
                                                                                        is-aubiquitin-dependent protein catabolic process via the N-end rule pathway


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aorganic substance metabolic process
                                is-amacromolecule metabolic process
                                        is-aprotein metabolic process
                                                is-aproteolysis
                                                        is-aproteolysis involved in cellular protein catabolic process
                                                                is-aproteasomal protein catabolic process
                                                                        is-aproteasome-mediated ubiquitin-dependent protein catabolic process
                                                                                is-aanaphase-promoting complex-dependent catabolic process +
                                                                                is-amitochondria-associated ubiquitin-dependent protein catabolic process
                                                                                negatively-regulatesnegative regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                positively-regulatespositive regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                part-ofprotein denaturation involved in proteasomal ubiquitin-dependent protein catabolic process
                                                                                regulatesregulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                is-aribosome-associated ubiquitin-dependent protein catabolic process
                                                                                is-aSCF-dependent proteasomal ubiquitin-dependent protein catabolic process
                                                                                is-atranscription factor catabolic process +
                                                                                is-aubiquitin-dependent catabolism of misfolded proteins by cytoplasm-associated proteasome
                                                                                is-aubiquitin-dependent catabolism of misfolded proteins by nucleus-associated proteasome +
                                                                                is-aubiquitin-dependent ERAD pathway [GO:0030433] (66 genes, 93 annotations)
                                                                                        negatively-regulatesnegative regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                        positively-regulatespositive regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                        regulatesregulation of ER-associated ubiquitin-dependent protein catabolic process +
                                                                                        is-aubiquitin-dependent glycoprotein ERAD pathway +
                                                                                is-aubiquitin-dependent protein catabolic process via the N-end rule pathway


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aorganic substance metabolic process
                                is-aorganic substance catabolic process
                                        is-amacromolecule catabolic process
                                                is-acellular macromolecule catabolic process
                                                        is-acellular protein catabolic process
                                                                part-ofproteolysis involved in cellular protein catabolic process
                                                                        is-amodification-dependent protein catabolic process
                                                                                is-aubiquitin-dependent protein catabolic process
                                                                                        is-aproteasome-mediated ubiquitin-dependent protein catabolic process
                                                                                                is-aanaphase-promoting complex-dependent catabolic process +
                                                                                                is-amitochondria-associated ubiquitin-dependent protein catabolic process
                                                                                                negatively-regulatesnegative regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                                positively-regulatespositive regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                                part-ofprotein denaturation involved in proteasomal ubiquitin-dependent protein catabolic process
                                                                                                regulatesregulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                                is-aribosome-associated ubiquitin-dependent protein catabolic process
                                                                                                is-aSCF-dependent proteasomal ubiquitin-dependent protein catabolic process
                                                                                                is-atranscription factor catabolic process +
                                                                                                is-aubiquitin-dependent catabolism of misfolded proteins by cytoplasm-associated proteasome
                                                                                                is-aubiquitin-dependent catabolism of misfolded proteins by nucleus-associated proteasome +
                                                                                                is-aubiquitin-dependent ERAD pathway [GO:0030433] (66 genes, 93 annotations)
                                                                                                        negatively-regulatesnegative regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                                        positively-regulatespositive regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                                        regulatesregulation of ER-associated ubiquitin-dependent protein catabolic process +
                                                                                                        is-aubiquitin-dependent glycoprotein ERAD pathway +
                                                                                                is-aubiquitin-dependent protein catabolic process via the N-end rule pathway


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aorganic substance metabolic process
                                is-aorganic substance catabolic process
                                        is-amacromolecule catabolic process
                                                is-acellular macromolecule catabolic process
                                                        is-acellular protein catabolic process
                                                                part-ofproteolysis involved in cellular protein catabolic process
                                                                        is-aproteasomal protein catabolic process
                                                                                is-aproteasome-mediated ubiquitin-dependent protein catabolic process
                                                                                        is-aanaphase-promoting complex-dependent catabolic process +
                                                                                        is-amitochondria-associated ubiquitin-dependent protein catabolic process
                                                                                        negatively-regulatesnegative regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                        positively-regulatespositive regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                        part-ofprotein denaturation involved in proteasomal ubiquitin-dependent protein catabolic process
                                                                                        regulatesregulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                        is-aribosome-associated ubiquitin-dependent protein catabolic process
                                                                                        is-aSCF-dependent proteasomal ubiquitin-dependent protein catabolic process
                                                                                        is-atranscription factor catabolic process +
                                                                                        is-aubiquitin-dependent catabolism of misfolded proteins by cytoplasm-associated proteasome
                                                                                        is-aubiquitin-dependent catabolism of misfolded proteins by nucleus-associated proteasome +
                                                                                        is-aubiquitin-dependent ERAD pathway [GO:0030433] (66 genes, 93 annotations)
                                                                                                negatively-regulatesnegative regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                                positively-regulatespositive regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                                regulatesregulation of ER-associated ubiquitin-dependent protein catabolic process +
                                                                                                is-aubiquitin-dependent glycoprotein ERAD pathway +
                                                                                        is-aubiquitin-dependent protein catabolic process via the N-end rule pathway


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aorganic substance metabolic process
                                is-aorganic substance catabolic process
                                        is-amacromolecule catabolic process
                                                is-acellular macromolecule catabolic process
                                                        is-amodification-dependent macromolecule catabolic process
                                                                is-amodification-dependent protein catabolic process
                                                                        is-aubiquitin-dependent protein catabolic process
                                                                                is-aproteasome-mediated ubiquitin-dependent protein catabolic process
                                                                                        is-aanaphase-promoting complex-dependent catabolic process +
                                                                                        is-amitochondria-associated ubiquitin-dependent protein catabolic process
                                                                                        negatively-regulatesnegative regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                        positively-regulatespositive regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                        part-ofprotein denaturation involved in proteasomal ubiquitin-dependent protein catabolic process
                                                                                        regulatesregulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                        is-aribosome-associated ubiquitin-dependent protein catabolic process
                                                                                        is-aSCF-dependent proteasomal ubiquitin-dependent protein catabolic process
                                                                                        is-atranscription factor catabolic process +
                                                                                        is-aubiquitin-dependent catabolism of misfolded proteins by cytoplasm-associated proteasome
                                                                                        is-aubiquitin-dependent catabolism of misfolded proteins by nucleus-associated proteasome +
                                                                                        is-aubiquitin-dependent ERAD pathway [GO:0030433] (66 genes, 93 annotations)
                                                                                                negatively-regulatesnegative regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                                positively-regulatespositive regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                                regulatesregulation of ER-associated ubiquitin-dependent protein catabolic process +
                                                                                                is-aubiquitin-dependent glycoprotein ERAD pathway +
                                                                                        is-aubiquitin-dependent protein catabolic process via the N-end rule pathway


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aorganic substance metabolic process
                                is-aorganic substance catabolic process
                                        is-amacromolecule catabolic process
                                                is-aprotein catabolic process
                                                        is-acellular protein catabolic process
                                                                part-ofproteolysis involved in cellular protein catabolic process
                                                                        is-amodification-dependent protein catabolic process
                                                                                is-aubiquitin-dependent protein catabolic process
                                                                                        is-aproteasome-mediated ubiquitin-dependent protein catabolic process
                                                                                                is-aanaphase-promoting complex-dependent catabolic process +
                                                                                                is-amitochondria-associated ubiquitin-dependent protein catabolic process
                                                                                                negatively-regulatesnegative regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                                positively-regulatespositive regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                                part-ofprotein denaturation involved in proteasomal ubiquitin-dependent protein catabolic process
                                                                                                regulatesregulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                                is-aribosome-associated ubiquitin-dependent protein catabolic process
                                                                                                is-aSCF-dependent proteasomal ubiquitin-dependent protein catabolic process
                                                                                                is-atranscription factor catabolic process +
                                                                                                is-aubiquitin-dependent catabolism of misfolded proteins by cytoplasm-associated proteasome
                                                                                                is-aubiquitin-dependent catabolism of misfolded proteins by nucleus-associated proteasome +
                                                                                                is-aubiquitin-dependent ERAD pathway [GO:0030433] (66 genes, 93 annotations)
                                                                                                        negatively-regulatesnegative regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                                        positively-regulatespositive regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                                        regulatesregulation of ER-associated ubiquitin-dependent protein catabolic process +
                                                                                                        is-aubiquitin-dependent glycoprotein ERAD pathway +
                                                                                                is-aubiquitin-dependent protein catabolic process via the N-end rule pathway


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aorganic substance metabolic process
                                is-aorganic substance catabolic process
                                        is-amacromolecule catabolic process
                                                is-aprotein catabolic process
                                                        is-acellular protein catabolic process
                                                                part-ofproteolysis involved in cellular protein catabolic process
                                                                        is-aproteasomal protein catabolic process
                                                                                is-aproteasome-mediated ubiquitin-dependent protein catabolic process
                                                                                        is-aanaphase-promoting complex-dependent catabolic process +
                                                                                        is-amitochondria-associated ubiquitin-dependent protein catabolic process
                                                                                        negatively-regulatesnegative regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                        positively-regulatespositive regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                        part-ofprotein denaturation involved in proteasomal ubiquitin-dependent protein catabolic process
                                                                                        regulatesregulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                        is-aribosome-associated ubiquitin-dependent protein catabolic process
                                                                                        is-aSCF-dependent proteasomal ubiquitin-dependent protein catabolic process
                                                                                        is-atranscription factor catabolic process +
                                                                                        is-aubiquitin-dependent catabolism of misfolded proteins by cytoplasm-associated proteasome
                                                                                        is-aubiquitin-dependent catabolism of misfolded proteins by nucleus-associated proteasome +
                                                                                        is-aubiquitin-dependent ERAD pathway [GO:0030433] (66 genes, 93 annotations)
                                                                                                negatively-regulatesnegative regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                                positively-regulatespositive regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                                regulatesregulation of ER-associated ubiquitin-dependent protein catabolic process +
                                                                                                is-aubiquitin-dependent glycoprotein ERAD pathway +
                                                                                        is-aubiquitin-dependent protein catabolic process via the N-end rule pathway


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aorganic substance metabolic process
                                is-aorganic substance catabolic process
                                        is-amacromolecule catabolic process
                                                is-aprotein catabolic process
                                                        is-aERAD pathway
                                                                is-aER-associated misfolded protein catabolic process
                                                                part-ofmaintenance of unfolded protein involved in ERAD pathway
                                                                negatively-regulatesnegative regulation of ERAD pathway +
                                                                positively-regulatespositive regulation of ERAD pathway +
                                                                part-ofprotein localization to cytosolic proteasome complex involved in ERAD pathway
                                                                regulatesregulation of ERAD pathway +
                                                                part-ofretrograde protein transport, ER to cytosol +
                                                                is-aubiquitin-dependent ERAD pathway [GO:0030433] (66 genes, 93 annotations)
                                                                        negatively-regulatesnegative regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                        positively-regulatespositive regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                        regulatesregulation of ER-associated ubiquitin-dependent protein catabolic process +
                                                                        is-aubiquitin-dependent glycoprotein ERAD pathway +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aorganic substance metabolic process
                                is-aorganic substance catabolic process
                                        is-amacromolecule catabolic process
                                                is-aprotein catabolic process
                                                        is-aproteasomal protein catabolic process
                                                                is-aproteasome-mediated ubiquitin-dependent protein catabolic process
                                                                        is-aanaphase-promoting complex-dependent catabolic process +
                                                                        is-amitochondria-associated ubiquitin-dependent protein catabolic process
                                                                        negatively-regulatesnegative regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                        positively-regulatespositive regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                        part-ofprotein denaturation involved in proteasomal ubiquitin-dependent protein catabolic process
                                                                        regulatesregulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                        is-aribosome-associated ubiquitin-dependent protein catabolic process
                                                                        is-aSCF-dependent proteasomal ubiquitin-dependent protein catabolic process
                                                                        is-atranscription factor catabolic process +
                                                                        is-aubiquitin-dependent catabolism of misfolded proteins by cytoplasm-associated proteasome
                                                                        is-aubiquitin-dependent catabolism of misfolded proteins by nucleus-associated proteasome +
                                                                        is-aubiquitin-dependent ERAD pathway [GO:0030433] (66 genes, 93 annotations)
                                                                                negatively-regulatesnegative regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                positively-regulatespositive regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                regulatesregulation of ER-associated ubiquitin-dependent protein catabolic process +
                                                                                is-aubiquitin-dependent glycoprotein ERAD pathway +
                                                                        is-aubiquitin-dependent protein catabolic process via the N-end rule pathway


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aprimary metabolic process
                                is-aprotein metabolic process
                                        is-acellular protein metabolic process
                                                is-acellular protein catabolic process
                                                        part-ofproteolysis involved in cellular protein catabolic process
                                                                is-amodification-dependent protein catabolic process
                                                                        is-aubiquitin-dependent protein catabolic process
                                                                                is-aproteasome-mediated ubiquitin-dependent protein catabolic process
                                                                                        is-aanaphase-promoting complex-dependent catabolic process +
                                                                                        is-amitochondria-associated ubiquitin-dependent protein catabolic process
                                                                                        negatively-regulatesnegative regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                        positively-regulatespositive regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                        part-ofprotein denaturation involved in proteasomal ubiquitin-dependent protein catabolic process
                                                                                        regulatesregulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                        is-aribosome-associated ubiquitin-dependent protein catabolic process
                                                                                        is-aSCF-dependent proteasomal ubiquitin-dependent protein catabolic process
                                                                                        is-atranscription factor catabolic process +
                                                                                        is-aubiquitin-dependent catabolism of misfolded proteins by cytoplasm-associated proteasome
                                                                                        is-aubiquitin-dependent catabolism of misfolded proteins by nucleus-associated proteasome +
                                                                                        is-aubiquitin-dependent ERAD pathway [GO:0030433] (66 genes, 93 annotations)
                                                                                                negatively-regulatesnegative regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                                positively-regulatespositive regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                                regulatesregulation of ER-associated ubiquitin-dependent protein catabolic process +
                                                                                                is-aubiquitin-dependent glycoprotein ERAD pathway +
                                                                                        is-aubiquitin-dependent protein catabolic process via the N-end rule pathway


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aprimary metabolic process
                                is-aprotein metabolic process
                                        is-acellular protein metabolic process
                                                is-acellular protein catabolic process
                                                        part-ofproteolysis involved in cellular protein catabolic process
                                                                is-aproteasomal protein catabolic process
                                                                        is-aproteasome-mediated ubiquitin-dependent protein catabolic process
                                                                                is-aanaphase-promoting complex-dependent catabolic process +
                                                                                is-amitochondria-associated ubiquitin-dependent protein catabolic process
                                                                                negatively-regulatesnegative regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                positively-regulatespositive regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                part-ofprotein denaturation involved in proteasomal ubiquitin-dependent protein catabolic process
                                                                                regulatesregulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                is-aribosome-associated ubiquitin-dependent protein catabolic process
                                                                                is-aSCF-dependent proteasomal ubiquitin-dependent protein catabolic process
                                                                                is-atranscription factor catabolic process +
                                                                                is-aubiquitin-dependent catabolism of misfolded proteins by cytoplasm-associated proteasome
                                                                                is-aubiquitin-dependent catabolism of misfolded proteins by nucleus-associated proteasome +
                                                                                is-aubiquitin-dependent ERAD pathway [GO:0030433] (66 genes, 93 annotations)
                                                                                        negatively-regulatesnegative regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                        positively-regulatespositive regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                        regulatesregulation of ER-associated ubiquitin-dependent protein catabolic process +
                                                                                        is-aubiquitin-dependent glycoprotein ERAD pathway +
                                                                                is-aubiquitin-dependent protein catabolic process via the N-end rule pathway


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aprimary metabolic process
                                is-aprotein metabolic process
                                        is-aprotein catabolic process
                                                is-acellular protein catabolic process
                                                        part-ofproteolysis involved in cellular protein catabolic process
                                                                is-amodification-dependent protein catabolic process
                                                                        is-aubiquitin-dependent protein catabolic process
                                                                                is-aproteasome-mediated ubiquitin-dependent protein catabolic process
                                                                                        is-aanaphase-promoting complex-dependent catabolic process +
                                                                                        is-amitochondria-associated ubiquitin-dependent protein catabolic process
                                                                                        negatively-regulatesnegative regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                        positively-regulatespositive regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                        part-ofprotein denaturation involved in proteasomal ubiquitin-dependent protein catabolic process
                                                                                        regulatesregulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                        is-aribosome-associated ubiquitin-dependent protein catabolic process
                                                                                        is-aSCF-dependent proteasomal ubiquitin-dependent protein catabolic process
                                                                                        is-atranscription factor catabolic process +
                                                                                        is-aubiquitin-dependent catabolism of misfolded proteins by cytoplasm-associated proteasome
                                                                                        is-aubiquitin-dependent catabolism of misfolded proteins by nucleus-associated proteasome +
                                                                                        is-aubiquitin-dependent ERAD pathway [GO:0030433] (66 genes, 93 annotations)
                                                                                                negatively-regulatesnegative regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                                positively-regulatespositive regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                                regulatesregulation of ER-associated ubiquitin-dependent protein catabolic process +
                                                                                                is-aubiquitin-dependent glycoprotein ERAD pathway +
                                                                                        is-aubiquitin-dependent protein catabolic process via the N-end rule pathway


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aprimary metabolic process
                                is-aprotein metabolic process
                                        is-aprotein catabolic process
                                                is-acellular protein catabolic process
                                                        part-ofproteolysis involved in cellular protein catabolic process
                                                                is-aproteasomal protein catabolic process
                                                                        is-aproteasome-mediated ubiquitin-dependent protein catabolic process
                                                                                is-aanaphase-promoting complex-dependent catabolic process +
                                                                                is-amitochondria-associated ubiquitin-dependent protein catabolic process
                                                                                negatively-regulatesnegative regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                positively-regulatespositive regulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                part-ofprotein denaturation involved in proteasomal ubiquitin-dependent protein catabolic process
                                                                                regulatesregulation of proteasomal ubiquitin-dependent protein catabolic process +
                                                                                is-aribosome-associated ubiquitin-dependent protein catabolic process
                                                                                is-aSCF-dependent proteasomal ubiquitin-dependent protein catabolic process
                                                                                is-atranscription factor catabolic process +
                                                                                is-aubiquitin-dependent catabolism of misfolded proteins by cytoplasm-associated proteasome
                                                                                is-aubiquitin-dependent catabolism of misfolded proteins by nucleus-associated proteasome +
                                                                                is-aubiquitin-dependent ERAD pathway [GO:0030433] (66 genes, 93 annotations)
                                                                                        negatively-regulatesnegative regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                        positively-regulatespositive regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                                        regulatesregulation of ER-associated ubiquitin-dependent protein catabolic process +
                                                                                        is-aubiquitin-dependent glycoprotein ERAD pathway +
                                                                                is-aubiquitin-dependent protein catabolic process via the N-end rule pathway


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aprimary metabolic process
                                is-aprotein metabolic process
                                        is-aprotein catabolic process
                                                is-aERAD pathway
                                                        is-aER-associated misfolded protein catabolic process
                                                        part-ofmaintenance of unfolded protein involved in ERAD pathway
                                                        negatively-regulatesnegative regulation of ERAD pathway +
                                                        positively-regulatespositive regulation of ERAD pathway +
                                                        part-ofprotein localization to cytosolic proteasome complex involved in ERAD pathway
                                                        regulatesregulation of ERAD pathway +
                                                        part-ofretrograde protein transport, ER to cytosol +
                                                        is-aubiquitin-dependent ERAD pathway [GO:0030433] (66 genes, 93 annotations)
                                                                negatively-regulatesnegative regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                positively-regulatespositive regulation of ER-associated ubiquitin-dependent protein catabolic process
                                                                regulatesregulation of ER-associated ubiquitin-dependent protein catabolic process +
                                                                is-aubiquitin-dependent glycoprotein ERAD pathway +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aprimary metabolic process
                                is-aprotein metabolic process
                                        is-aprotein catabolic process
                                                is-aproteasomal protein catabolic process
                                                        is-aproteasome-mediated ubiquitin-dependent protein catabolic process
                                &n