Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NGFR
  • Mouse genes Ngfr
  • Rat genes Ngfr
  • Zfish genes ngfra,ngfrb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ngfr

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001540	amyloid-beta binding	Ngfr	IPI	RGD:2139	Rat	PMID:19334058|RGD:5508225
Molecular Function	GO:0005516	calmodulin binding	NGFR	IDA		Human	PMID:24914971
Molecular Function	GO:0015026	coreceptor activity	NGFR	IDA		Human	PMID:16712417
Molecular Function	GO:0005035	death receptor activity	NGFR	IGI	UniProtKB:P01138:PRO_0000019600|UniProtKB:P05067:PRO_0000000092	Human	PMID:11927634
Molecular Function	GO:0005035	death receptor activity	Ngfr	IDA		Mouse	PMID:10764727
Molecular Function	GO:0042802	identical protein binding	Ngfr	IPI	UniProtKB:P07174	Rat	PMID:11756426|RGD:8554493
Molecular Function	GO:0042802	identical protein binding	Ngfr	IPI	UniProtKB:P07174	Rat	PMID:18596692|RGD:5508745
Molecular Function	GO:0042802	identical protein binding	Ngfr	IPI	RGD:3177	Rat	PMID:23472109|RGD:10413904
Molecular Function	GO:0048406	nerve growth factor binding	Ngfr	IDA		Mouse	PMID:1317267
Molecular Function	GO:0048406	nerve growth factor binding	Ngfr	IDA		Rat	PMID:3027580|RGD:728964
Molecular Function	GO:0043121	neurotrophin binding	Ngfr	IPI	RGD:732368	Rat	PMID:18596692|RGD:5508745
Molecular Function	GO:0005168	neurotrophin TRKA receptor binding	Ngfr	IPI	RGD:620144	Rat	PMID:9753156|RGD:5508802
Molecular Function	GO:0070678	preprotein binding	Ngfr	IPI	RGD:10978	Rat	PMID:20036257|RGD:5508717
Molecular Function	GO:0005515	protein binding	NGFR	IPI	UniProtKB:P05067:PRO_0000000093	Human	PMID:11756426
Molecular Function	GO:0005515	protein binding	NGFR	IPI	UniProtKB:P25233	Human	PMID:14593116
Molecular Function	GO:0005515	protein binding	NGFR	IPI	UniProtKB:Q9CPR8	Human	PMID:14593116
Molecular Function	GO:0005515	protein binding	NGFR	IPI	UniProtKB:Q96FE5	Human	PMID:14966521
Molecular Function	GO:0005515	protein binding	NGFR	IPI	UniProtKB:P01138	Human	PMID:14985763
Molecular Function	GO:0005515	protein binding	NGFR	IPI	UniProtKB:P01138:PRO_0000019600	Human	PMID:14985763
Molecular Function	GO:0005515	protein binding	NGFR	IPI	UniProtKB:Q9Y467	Human	PMID:19131967
Molecular Function	GO:0005515	protein binding	NGFR	IPI	UniProtKB:P05067	Human	PMID:19225519
Molecular Function	GO:0005515	protein binding	NGFR	IPI	UniProtKB:Q96FE5	Human	PMID:20659559
Molecular Function	GO:0005515	protein binding	NGFR	IPI	UniProtKB:P33681	Human	PMID:21982860
Molecular Function	GO:0005515	protein binding	NGFR	IPI	UniProtKB:O75509	Human	PMID:23559013
Molecular Function	GO:0005515	protein binding	NGFR	IPI	UniProtKB:Q7Z699	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NGFR	IPI	UniProtKB:Q9UNE7	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Ngfr	IPI	UniProtKB:Q923B3	Mouse	MGI:MGI:1929440|PMID:10545116
Molecular Function	GO:0005515	protein binding	Ngfr	IPI	UniProtKB:Q923B3	Mouse	MGI:MGI:3579762|PMID:15668238
Molecular Function	GO:0005515	protein binding	Ngfr	IPI	UniProtKB:Q9EPR5	Mouse	MGI:MGI:5603952|PMID:24908487
Molecular Function	GO:0005515	protein binding	Ngfr	IPI	PR:Q3UFB7	Mouse	PMID:16049186
Molecular Function	GO:0005515	protein binding	Ngfr	IPI	PR:P25233	Mouse	PMID:16049186
Molecular Function	GO:0005515	protein binding	Ngfr	IPI	PR:Q921B4	Mouse	PMID:11750124
Molecular Function	GO:0005515	protein binding	Ngfr	IPI	RGD:619929	Rat	PMID:10485890|RGD:633619
Molecular Function	GO:0005515	protein binding	Ngfr	IPI	UniProtKB:Q12933	Rat	PMID:10514511|RGD:8554701
Molecular Function	GO:0005515	protein binding	Ngfr	IPI	UniProtKB:Q9BUZ4	Rat	PMID:10514511|RGD:8554701
Molecular Function	GO:0005515	protein binding	Ngfr	IPI	UniProtKB:Q9Y4K3	Rat	PMID:10514511|RGD:8554701
Molecular Function	GO:0005515	protein binding	Ngfr	IPI	RGD:3148	Rat	PMID:10764727|RGD:633451
Molecular Function	GO:0005515	protein binding	Ngfr	IPI	UniProtKB:P05067:PRO_0000000093	Rat	PMID:11756426|RGD:8554493
Molecular Function	GO:0005515	protein binding	Ngfr	IPI	RGD:708524	Rat	PMID:12095158|RGD:1299507
Molecular Function	GO:0005515	protein binding	Ngfr	IPI	RGD:1310526	Rat	PMID:12414813|RGD:729117
Molecular Function	GO:0005515	protein binding	Ngfr	IPI	UniProtKB:P01138	Rat	PMID:14985763|RGD:10047349
Molecular Function	GO:0005515	protein binding	Ngfr	IPI	UniProtKB:P01138	Rat	PMID:15131306|RGD:10047380
Molecular Function	GO:0005515	protein binding	Ngfr	IPI	UniProtKB:Q3MKQ2	Rat	PMID:16498402|RGD:8554704
Molecular Function	GO:0005515	protein binding	Ngfr	IPI	UniProtKB:P01138	Rat	PMID:18596692|RGD:5508745
Molecular Function	GO:0005515	protein binding	Ngfr	IPI	UniProtKB:P20783	Rat	PMID:18596692|RGD:5508745
Molecular Function	GO:0005515	protein binding	Ngfr	IPI	UniProtKB:P35739	Rat	PMID:19549834|RGD:13432330
Molecular Function	GO:0005515	protein binding	Ngfr	IPI	UniProtKB:Q9Y4K3	Rat	PMID:21541365|RGD:8554787
Molecular Function	GO:0005515	protein binding	ngfrb	IPI	ZFIN:ZDB-GENE-030131-6760	Zfish	PMID:24466042
Molecular Function	GO:0044877	protein-containing complex binding	Ngfr	IPI	RGD:631413|RGD:620810	Rat	PMID:23613963|RGD:14390159
Molecular Function	GO:0031267	small GTPase binding	Ngfr	IDA		Mouse	MGI:MGI:5318890|PMID:22460790
Molecular Function	GO:0031625	ubiquitin protein ligase binding	NGFR	IPI	UniProtKB:O94972	Human	PMID:11279055
Molecular Function	GO:0031625	ubiquitin protein ligase binding	NGFR	IPI	UniProtKB:Q12933	Human	PMID:11279055
Cellular Component	GO:0009986	cell surface	Ngfr	IDA		Mouse	MGI:MGI:1330409|PMID:10021336
Cellular Component	GO:0005911	cell-cell junction	Ngfr	IDA		Mouse	PMID:21300049
Cellular Component	GO:0045334	clathrin-coated endocytic vesicle	Ngfr	IDA		Rat	PMID:17897318|RGD:5508756
Cellular Component	GO:0030135	coated vesicle	Ngfr	IDA		Rat	PMID:9521535|RGD:5508789
Cellular Component	GO:0005737	cytoplasm	Ngfr	IDA		Mouse	PMID:19295126
Cellular Component	GO:0005737	cytoplasm	Ngfr	IDA		Mouse	PMID:25433207
Cellular Component	GO:0005737	cytoplasm	Ngfr	IDA		Rat	PMID:15703394|RGD:1580250
Cellular Component	GO:0032590	dendrite membrane	Ngfr	IDA		Rat	PMID:9521535|RGD:5508789
Cellular Component	GO:0009897	external side of plasma membrane	Ngfr	IDA		Rat	PMID:9521535|RGD:5508789
Cellular Component	GO:0005794	Golgi apparatus	Ngfr	IDA		Rat	PMID:9521535|RGD:5508789
Cellular Component	GO:0045121	membrane raft	Ngfr	IDA		Rat	PMID:17433308|RGD:1626321
Cellular Component	GO:0005739	mitochondrion	Ngfr	IDA		Rat	PMID:22138126|RGD:10414075
Cellular Component	GO:0031594	neuromuscular junction	Ngfr	IDA		Mouse	PMID:31514753
Cellular Component	GO:0031594	neuromuscular junction	Ngfr	IMP		Mouse	PMID:31514753
Cellular Component	GO:0031594	neuromuscular junction	Ngfr	IDA		Rat	PMID:20433604|RGD:155230760
Cellular Component	GO:0032809	neuronal cell body membrane	Ngfr	IDA		Rat	PMID:9521535|RGD:5508789
Cellular Component	GO:0005635	nuclear envelope	Ngfr	IDA		Rat	PMID:9521535|RGD:5508789
Cellular Component	GO:0005654	nucleoplasm	NGFR	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Ngfr	IDA		Rat	PMID:15703394|RGD:1580250
Cellular Component	GO:0043204	perikaryon	Ngfr	IDA		Rat	PMID:9767155|RGD:5508385
Cellular Component	GO:0005886	plasma membrane	NGFR	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	NGFR	IDA		Human	PMID:16712417
Cellular Component	GO:0005886	plasma membrane	Ngfr	IDA		Mouse	PMID:10536054
Cellular Component	GO:0005886	plasma membrane	Ngfr	IDA		Rat	PMID:3027580|RGD:728964
Cellular Component	GO:0014069	postsynaptic density	Ngfr	IDA		Mouse	PMID:24069373
Cellular Component	GO:0098793	presynapse	Ngfr	IMP		Mouse	MGI:MGI:6452757|PMID:31514753
Cellular Component	GO:0042734	presynaptic membrane	Ngfr	IDA		Rat	PMID:20433604|RGD:155230760
Cellular Component	GO:0005791	rough endoplasmic reticulum	Ngfr	IDA		Rat	PMID:9521535|RGD:5508789
Biological Process	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	NGFR	IMP		Human	PMID:26268439
Biological Process	GO:0007411	axon guidance	Ngfr	IMP	MGI:MGI:1857226	Mouse	PMID:11978834
Biological Process	GO:1904646	cellular response to amyloid-beta	NGFR	IDA		Human	PMID:11927634
Biological Process	GO:0034599	cellular response to oxidative stress	Ngfr	IMP		Rat	PMID:19457114|RGD:5508731
Biological Process	GO:0007417	central nervous system development	Ngfr	IMP	MGI:MGI:1857226	Mouse	PMID:11978834
Biological Process	GO:0032922	circadian regulation of gene expression	Ngfr	IMP		Mouse	MGI:MGI:5503234|PMID:23785138
Biological Process	GO:0007623	circadian rhythm	Ngfr	IEP		Mouse	MGI:MGI:5503234|PMID:23785138
Biological Process	GO:0016048	detection of temperature stimulus	Ngfr	IMP	MGI:MGI:1857226	Mouse	PMID:1317267
Biological Process	GO:0035907	dorsal aorta development	Ngfr	IMP		Mouse	MGI:MGI:2151307|PMID:11559852
Biological Process	GO:0008543	fibroblast growth factor receptor signaling pathway	Ngfr	IMP	MGI:MGI:1857226	Mouse	PMID:10588868
Biological Process	GO:0048144	fibroblast proliferation	Ngfr	IMP	MGI:MGI:1857226	Mouse	PMID:10588868
Biological Process	GO:0042593	glucose homeostasis	Ngfr	IMP		Mouse	MGI:MGI:5318890|PMID:22460790
Biological Process	GO:0001942	hair follicle development	Ngfr	IMP	MGI:MGI:1857226	Mouse	PMID:10588868
Biological Process	GO:0031069	hair follicle morphogenesis	Ngfr	IMP	MGI:MGI:1857226	Mouse	PMID:10588868
Biological Process	GO:0001678	intracellular glucose homeostasis	Ngfr	IMP		Mouse	MGI:MGI:5318890|PMID:22460790
Biological Process	GO:0006886	intracellular protein transport	Ngfr	IMP		Mouse	MGI:MGI:5318890|PMID:22460790
Biological Process	GO:0001822	kidney development	ngfrb	IMP	ZFIN:ZDB-MRPHLNO-140522-2	Zfish	PMID:32988586
Biological Process	GO:0016525	negative regulation of angiogenesis	Ngfr	IMP		Rat	PMID:23920372|RGD:10413902
Biological Process	GO:0043066	negative regulation of apoptotic process	Ngfr	IMP		Rat	PMID:23920372|RGD:10413902
Biological Process	GO:1903588	negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis	NGFR	IGI	RNAcentral:URS00000F6E49_9606	Human	PMID:26268439
Biological Process	GO:0030336	negative regulation of cell migration	NGFR	IMP		Human	PMID:27927008
Biological Process	GO:0061000	negative regulation of dendritic spine development	Ngfr	IMP		Rat	PMID:22548193|RGD:10413901
Biological Process	GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway	Ngfr	IMP	MGI:MGI:1857226	Mouse	PMID:10588868
Biological Process	GO:0051799	negative regulation of hair follicle development	Ngfr	IMP	MGI:MGI:1857226	Mouse	PMID:10588868
Biological Process	GO:0051902	negative regulation of mitochondrial depolarization	Ngfr	IMP		Rat	PMID:19457114|RGD:5508731
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	Ngfr	IMP		Rat	PMID:11438587|RGD:5508783
Biological Process	GO:0010977	negative regulation of neuron projection development	Ngfr	IDA		Rat	PMID:18786176|RGD:5508741
Biological Process	GO:0021675	nerve development	Ngfr	IMP	MGI:MGI:1857226	Mouse	PMID:1317267
Biological Process	GO:0051402	neuron apoptotic process	NGFR	IGI	UniProtKB:P01138:PRO_0000019600	Human	PMID:11927634
Biological Process	GO:0042475	odontogenesis of dentin-containing tooth	Ngfr	IMP	MGI:MGI:1857226	Mouse	PMID:9268129
Biological Process	GO:0043065	positive regulation of apoptotic process	Ngfr	IMP		Rat	PMID:21539892|RGD:5144126
Biological Process	GO:2001235	positive regulation of apoptotic signaling pathway	Ngfr	IDA		Mouse	PMID:10764727
Biological Process	GO:2000463	positive regulation of excitatory postsynaptic potential	Ngfr	IMP		Rat	PMID:23114219|RGD:10414080
Biological Process	GO:0048146	positive regulation of fibroblast proliferation	Ngfr	IMP	MGI:MGI:1857226	Mouse	PMID:10588868
Biological Process	GO:0043410	positive regulation of MAPK cascade	Ngfr	IDA		Rat	PMID:12929129|RGD:5508773
Biological Process	GO:1902895	positive regulation of miRNA transcription	NGFR	IDA		Human	PMID:26268439
Biological Process	GO:0031643	positive regulation of myelination	Ngfr	IMP		Rat	PMID:12424382|RGD:5508778
Biological Process	GO:2000179	positive regulation of neural precursor cell proliferation	Ngfr	IMP		Rat	PMID:23940017|RGD:10414074
Biological Process	GO:1901216	positive regulation of neuron death	Ngfr	IDA		Rat	PMID:20943663|RGD:5508695
Biological Process	GO:0045666	positive regulation of neuron differentiation	Ngfr	IDA		Rat	PMID:23940017|RGD:10414074
Biological Process	GO:0010976	positive regulation of neuron projection development	Ngfr	IMP		Rat	PMID:22292018|RGD:10413903
Biological Process	GO:0042488	positive regulation of odontogenesis of dentin-containing tooth	Ngfr	IMP	MGI:MGI:1857226	Mouse	PMID:9268129
Biological Process	GO:0051897	positive regulation of protein kinase B signaling	Ngfr	IDA		Rat	PMID:19457114|RGD:5508731
Biological Process	GO:1900182	positive regulation of protein localization to nucleus	NGFR	IDA		Human	PMID:26268439
Biological Process	GO:0035025	positive regulation of Rho protein signal transduction	Ngfr	IDA		Rat	PMID:18786176|RGD:5508741
Biological Process	GO:0032224	positive regulation of synaptic transmission, cholinergic	Ngfr	IMP		Rat	PMID:18256260|RGD:5508750
Biological Process	GO:0051968	positive regulation of synaptic transmission, glutamatergic	Ngfr	IMP		Rat	PMID:18256260|RGD:5508750
Biological Process	GO:0048916	posterior lateral line development	ngfrb	IMP	ZFIN:ZDB-MRPHLNO-140522-2	Zfish	PMID:24466042
Biological Process	GO:0048922	posterior lateral line neuromast deposition	ngfrb	IMP	ZFIN:ZDB-MRPHLNO-140522-2	Zfish	PMID:24466042
Biological Process	GO:0099171	presynaptic modulation of chemical synaptic transmission	Ngfr	IDA		Mouse	PMID:31514753
Biological Process	GO:0099171	presynaptic modulation of chemical synaptic transmission	Ngfr	IMP		Mouse	PMID:31514753
Biological Process	GO:0010468	regulation of gene expression	Ngfr	IMP	MGI:MGI:1857226	Mouse	PMID:10588868
Biological Process	GO:2000377	regulation of reactive oxygen species metabolic process	Ngfr	IMP		Rat	PMID:19457114|RGD:5508731
Biological Process	GO:0032496	response to lipopolysaccharide	Ngfr	IEP		Rat	PMID:21084570|RGD:5144146
Biological Process	GO:0009611	response to wounding	Ngfr	IMP		Rat	PMID:12408842|RGD:625697
Biological Process	GO:0007266	Rho protein signal transduction	NGFR	IDA		Human	PMID:16712417
Biological Process	GO:0019233	sensory perception of pain	Ngfr	IMP		Rat	PMID:20060234|RGD:5144063
Biological Process	GO:0007165	signal transduction	Ngfr	IDA		Rat	PMID:12408842|RGD:625697
Biological Process	GO:0035914	skeletal muscle cell differentiation	Ngfr	IEP		Rat	PMID:16723531|RGD:1580249
Biological Process	GO:0043588	skin development	Ngfr	IMP	MGI:MGI:1857226	Mouse	PMID:1317267

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern