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Gene Ontology Browser
Term Detail
GO term:skin development
Synonym: animal skin development
GO id:GO:0043588
Definition:The process whose specific outcome is the progression of the skin over time, from its formation to the mature structure. The skin is the external membranous integument of an animal. In vertebrates the skin generally consists of two layers, an outer nonsensitive and nonvascular epidermis (cuticle or skarfskin) composed of cells which are constantly growing and multiplying in the deeper, and being thrown off in the superficial layers, as well as an inner vascular dermis (cutis, corium or true skin) composed mostly of connective tissue.
Number of paths to term: 7

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


obsolete Gene_Ontology
        is-abiological_process
                is-adevelopmental process
                        is-aanatomical structure development
                                is-aanimal organ development
                                        part-ofadipose tissue development +
                                        part-ofanimal organ maturation +
                                        part-ofanimal organ morphogenesis +
                                        is-aanimal organ regeneration +
                                        part-ofanimal organ senescence
                                        part-ofbiomineral tissue development +
                                        is-abone development +
                                        is-abrain development +
                                        part-ofcarotid body glomus cell differentiation
                                        is-acartilage development +
                                        part-ofconvergent extension involved in organogenesis +
                                        is-aembryonic organ development +
                                        is-aesophagus development
                                        is-afat body development +
                                        is-agall bladder development
                                        is-aganglion development +
                                        is-agenitalia development +
                                        is-agland development +
                                        is-agonad development +
                                        is-aheart development +
                                        is-ahematopoietic or lymphoid organ development +
                                        is-aimaginal disc development +
                                        is-akidney development +
                                        is-alung development +
                                        part-ofmaintenance of animal organ identity +
                                        is-aMalpighian tubule development +
                                        part-ofmesenchyme development +
                                        part-ofmulticellular structure septum development
                                        is-amuscle organ development +
                                        is-apancreas development +
                                        is-aplacenta development +
                                        is-apost-embryonic animal organ development +
                                        is-aproboscis development +
                                        is-arespiratory tube development +
                                        is-asensory organ development +
                                        is-askin development [GO:0043588] (271 genes, 409 annotations)
                                                part-ofestablishment of skin barrier
                                                part-ofkeratinocyte differentiation +
                                                part-ofsebaceous gland development +
                                                part-ofskin epidermis development +
                                                part-ofskin morphogenesis
                                        is-aspinal cord development +
                                        part-ofstomach neuroendocrine cell differentiation +
                                        is-aswim bladder development +
                                        is-atrachea development +
                                        is-aureter development +
                                        is-aurethra development +
                                        is-aurinary bladder development
                                        is-auterus development +
                                        is-aventral cord development


obsolete Gene_Ontology
        is-abiological_process
                is-adevelopmental process
                        is-aanatomical structure development
                                is-amulticellular organism development
                                        part-ofsystem development
                                                part-ofanimal organ development
                                                        part-ofadipose tissue development +
                                                        part-ofanimal organ maturation +
                                                        part-ofanimal organ morphogenesis +
                                                        is-aanimal organ regeneration +
                                                        part-ofanimal organ senescence
                                                        part-ofbiomineral tissue development +
                                                        is-abone development +
                                                        is-abrain development +
                                                        part-ofcarotid body glomus cell differentiation
                                                        is-acartilage development +
                                                        part-ofconvergent extension involved in organogenesis +
                                                        is-aembryonic organ development +
                                                        is-aesophagus development
                                                        is-afat body development +
                                                        is-agall bladder development
                                                        is-aganglion development +
                                                        is-agenitalia development +
                                                        is-agland development +
                                                        is-agonad development +
                                                        is-aheart development +
                                                        is-ahematopoietic or lymphoid organ development +
                                                        is-aimaginal disc development +
                                                        is-akidney development +
                                                        is-alung development +
                                                        part-ofmaintenance of animal organ identity +
                                                        is-aMalpighian tubule development +
                                                        part-ofmesenchyme development +
                                                        part-ofmulticellular structure septum development
                                                        is-amuscle organ development +
                                                        is-apancreas development +
                                                        is-aplacenta development +
                                                        is-apost-embryonic animal organ development +
                                                        is-aproboscis development +
                                                        is-arespiratory tube development +
                                                        is-asensory organ development +
                                                        is-askin development [GO:0043588] (271 genes, 409 annotations)
                                                                part-ofestablishment of skin barrier
                                                                part-ofkeratinocyte differentiation +
                                                                part-ofsebaceous gland development +
                                                                part-ofskin epidermis development +
                                                                part-ofskin morphogenesis
                                                        is-aspinal cord development +
                                                        part-ofstomach neuroendocrine cell differentiation +
                                                        is-aswim bladder development +
                                                        is-atrachea development +
                                                        is-aureter development +
                                                        is-aurethra development +
                                                        is-aurinary bladder development
                                                        is-auterus development +
                                                        is-aventral cord development


obsolete Gene_Ontology
        is-abiological_process
                is-adevelopmental process
                        is-aanatomical structure development
                                is-asystem development
                                        part-ofanimal organ development
                                                part-ofadipose tissue development +
                                                part-ofanimal organ maturation +
                                                part-ofanimal organ morphogenesis +
                                                is-aanimal organ regeneration +
                                                part-ofanimal organ senescence
                                                part-ofbiomineral tissue development +
                                                is-abone development +
                                                is-abrain development +
                                                part-ofcarotid body glomus cell differentiation
                                                is-acartilage development +
                                                part-ofconvergent extension involved in organogenesis +
                                                is-aembryonic organ development +
                                                is-aesophagus development
                                                is-afat body development +
                                                is-agall bladder development
                                                is-aganglion development +
                                                is-agenitalia development +
                                                is-agland development +
                                                is-agonad development +
                                                is-aheart development +
                                                is-ahematopoietic or lymphoid organ development +
                                                is-aimaginal disc development +
                                                is-akidney development +
                                                is-alung development +
                                                part-ofmaintenance of animal organ identity +
                                                is-aMalpighian tubule development +
                                                part-ofmesenchyme development +
                                                part-ofmulticellular structure septum development
                                                is-amuscle organ development +
                                                is-apancreas development +
                                                is-aplacenta development +
                                                is-apost-embryonic animal organ development +
                                                is-aproboscis development +
                                                is-arespiratory tube development +
                                                is-asensory organ development +
                                                is-askin development [GO:0043588] (271 genes, 409 annotations)
                                                        part-ofestablishment of skin barrier
                                                        part-ofkeratinocyte differentiation +
                                                        part-ofsebaceous gland development +
                                                        part-ofskin epidermis development +
                                                        part-ofskin morphogenesis
                                                is-aspinal cord development +
                                                part-ofstomach neuroendocrine cell differentiation +
                                                is-aswim bladder development +
                                                is-atrachea development +
                                                is-aureter development +
                                                is-aurethra development +
                                                is-aurinary bladder development
                                                is-auterus development +
                                                is-aventral cord development


obsolete Gene_Ontology
        is-abiological_process
                is-adevelopmental process
                        is-asingle-organism developmental process
                                is-amulticellular organism development
                                        part-ofsystem development
                                                part-ofanimal organ development
                                                        part-ofadipose tissue development +
                                                        part-ofanimal organ maturation +
                                                        part-ofanimal organ morphogenesis +
                                                        is-aanimal organ regeneration +
                                                        part-ofanimal organ senescence
                                                        part-ofbiomineral tissue development +
                                                        is-abone development +
                                                        is-abrain development +
                                                        part-ofcarotid body glomus cell differentiation
                                                        is-acartilage development +
                                                        part-ofconvergent extension involved in organogenesis +
                                                        is-aembryonic organ development +
                                                        is-aesophagus development
                                                        is-afat body development +
                                                        is-agall bladder development
                                                        is-aganglion development +
                                                        is-agenitalia development +
                                                        is-agland development +
                                                        is-agonad development +
                                                        is-aheart development +
                                                        is-ahematopoietic or lymphoid organ development +
                                                        is-aimaginal disc development +
                                                        is-akidney development +
                                                        is-alung development +
                                                        part-ofmaintenance of animal organ identity +
                                                        is-aMalpighian tubule development +
                                                        part-ofmesenchyme development +
                                                        part-ofmulticellular structure septum development
                                                        is-amuscle organ development +
                                                        is-apancreas development +
                                                        is-aplacenta development +
                                                        is-apost-embryonic animal organ development +
                                                        is-aproboscis development +
                                                        is-arespiratory tube development +
                                                        is-asensory organ development +
                                                        is-askin development [GO:0043588] (271 genes, 409 annotations)
                                                                part-ofestablishment of skin barrier
                                                                part-ofkeratinocyte differentiation +
                                                                part-ofsebaceous gland development +
                                                                part-ofskin epidermis development +
                                                                part-ofskin morphogenesis
                                                        is-aspinal cord development +
                                                        part-ofstomach neuroendocrine cell differentiation +
                                                        is-aswim bladder development +
                                                        is-atrachea development +
                                                        is-aureter development +
                                                        is-aurethra development +
                                                        is-aurinary bladder development
                                                        is-auterus development +
                                                        is-aventral cord development


obsolete Gene_Ontology
        is-abiological_process
                is-amulticellular organismal process
                        is-asingle-multicellular organism process
                                is-amulticellular organism development
                                        part-ofsystem development
                                                part-ofanimal organ development
                                                        part-ofadipose tissue development +
                                                        part-ofanimal organ maturation +
                                                        part-ofanimal organ morphogenesis +
                                                        is-aanimal organ regeneration +
                                                        part-ofanimal organ senescence
                                                        part-ofbiomineral tissue development +
                                                        is-abone development +
                                                        is-abrain development +
                                                        part-ofcarotid body glomus cell differentiation
                                                        is-acartilage development +
                                                        part-ofconvergent extension involved in organogenesis +
                                                        is-aembryonic organ development +
                                                        is-aesophagus development
                                                        is-afat body development +
                                                        is-agall bladder development
                                                        is-aganglion development +
                                                        is-agenitalia development +
                                                        is-agland development +
                                                        is-agonad development +
                                                        is-aheart development +
                                                        is-ahematopoietic or lymphoid organ development +
                                                        is-aimaginal disc development +
                                                        is-akidney development +
                                                        is-alung development +
                                                        part-ofmaintenance of animal organ identity +
                                                        is-aMalpighian tubule development +
                                                        part-ofmesenchyme development +
                                                        part-ofmulticellular structure septum development
                                                        is-amuscle organ development +
                                                        is-apancreas development +
                                                        is-aplacenta development +
                                                        is-apost-embryonic animal organ development +
                                                        is-aproboscis development +
                                                        is-arespiratory tube development +
                                                        is-asensory organ development +
                                                        is-askin development [GO:0043588] (271 genes, 409 annotations)
                                                                part-ofestablishment of skin barrier
                                                                part-ofkeratinocyte differentiation +
                                                                part-ofsebaceous gland development +
                                                                part-ofskin epidermis development +
                                                                part-ofskin morphogenesis
                                                        is-aspinal cord development +
                                                        part-ofstomach neuroendocrine cell differentiation +
                                                        is-aswim bladder development +
                                                        is-atrachea development +
                                                        is-aureter development +
                                                        is-aurethra development +
                                                        is-aurinary bladder development
                                                        is-auterus development +
                                                        is-aventral cord development


obsolete Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-multicellular organism process
                                is-amulticellular organism development
                                        part-ofsystem development
                                                part-ofanimal organ development
                                                        part-ofadipose tissue development +
                                                        part-ofanimal organ maturation +
                                                        part-ofanimal organ morphogenesis +
                                                        is-aanimal organ regeneration +
                                                        part-ofanimal organ senescence
                                                        part-ofbiomineral tissue development +
                                                        is-abone development +
                                                        is-abrain development +
                                                        part-ofcarotid body glomus cell differentiation
                                                        is-acartilage development +
                                                        part-ofconvergent extension involved in organogenesis +
                                                        is-aembryonic organ development +
                                                        is-aesophagus development
                                                        is-afat body development +
                                                        is-agall bladder development
                                                        is-aganglion development +
                                                        is-agenitalia development +
                                                        is-agland development +
                                                        is-agonad development +
                                                        is-aheart development +
                                                        is-ahematopoietic or lymphoid organ development +
                                                        is-aimaginal disc development +
                                                        is-akidney development +
                                                        is-alung development +
                                                        part-ofmaintenance of animal organ identity +
                                                        is-aMalpighian tubule development +
                                                        part-ofmesenchyme development +
                                                        part-ofmulticellular structure septum development
                                                        is-amuscle organ development +
                                                        is-apancreas development +
                                                        is-aplacenta development +
                                                        is-apost-embryonic animal organ development +
                                                        is-aproboscis development +
                                                        is-arespiratory tube development +
                                                        is-asensory organ development +
                                                        is-askin development [GO:0043588] (271 genes, 409 annotations)
                                                                part-ofestablishment of skin barrier
                                                                part-ofkeratinocyte differentiation +
                                                                part-ofsebaceous gland development +
                                                                part-ofskin epidermis development +
                                                                part-ofskin morphogenesis
                                                        is-aspinal cord development +
                                                        part-ofstomach neuroendocrine cell differentiation +
                                                        is-aswim bladder development +
                                                        is-atrachea development +
                                                        is-aureter development +
                                                        is-aurethra development +
                                                        is-aurinary bladder development
                                                        is-auterus development +
                                                        is-aventral cord development


obsolete Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism developmental process
                                is-amulticellular organism development
                                        part-ofsystem development
                                                part-ofanimal organ development
                                                        part-ofadipose tissue development +
                                                        part-ofanimal organ maturation +
                                                        part-ofanimal organ morphogenesis +
                                                        is-aanimal organ regeneration +
                                                        part-ofanimal organ senescence
                                                        part-ofbiomineral tissue development +
                                                        is-abone development +
                                                        is-abrain development +
                                                        part-ofcarotid body glomus cell differentiation
                                                        is-acartilage development +
                                                        part-ofconvergent extension involved in organogenesis +
                                                        is-aembryonic organ development +
                                                        is-aesophagus development
                                                        is-afat body development +
                                                        is-agall bladder development
                                                        is-aganglion development +
                                                        is-agenitalia development +
                                                        is-agland development +
                                                        is-agonad development +
                                                        is-aheart development +
                                                        is-ahematopoietic or lymphoid organ development +
                                                        is-aimaginal disc development +
                                                        is-akidney development +
                                                        is-alung development +
                                                        part-ofmaintenance of animal organ identity +
                                                        is-aMalpighian tubule development +
                                                        part-ofmesenchyme development +
                                                        part-ofmulticellular structure septum development
                                                        is-amuscle organ development +
                                                        is-apancreas development +
                                                        is-aplacenta development +
                                                        is-apost-embryonic animal organ development +
                                                        is-aproboscis development +
                                                        is-arespiratory tube development +
                                                        is-asensory organ development +
                                                        is-askin development [GO:0043588] (271 genes, 409 annotations)
                                                                part-ofestablishment of skin barrier
                                                                part-ofkeratinocyte differentiation +
                                                                part-ofsebaceous gland development +
                                                                part-ofskin epidermis development +
                                                                part-ofskin morphogenesis
                                                        is-aspinal cord development +
                                                        part-ofstomach neuroendocrine cell differentiation +
                                                        is-aswim bladder development +
                                                        is-atrachea development +
                                                        is-aureter development +
                                                        is-aurethra development +
                                                        is-aurinary bladder development
                                                        is-auterus development +
                                                        is-aventral cord development


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last database update
09/13/2016
MGI 6.05
The Jackson Laboratory