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Gene Ontology Browser
Term Detail
GO term:rough endoplasmic reticulum
Synonym: RER
Synonym: rough ER
GO id:GO:0005791
Definition:The rough (or granular) endoplasmic reticulum (ER) has ribosomes adhering to the outer surface; the ribosomes are the site of translation of the mRNA for those proteins which are either to be retained within the cisternae (ER-resident proteins), the proteins of the lysosomes, or the proteins destined for export from the cell. Glycoproteins undergo their initial glycosylation within the cisternae.
Number of paths to term: 16

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-acellular_component
                is-acell
                        part-ofcell part
                                is-aendomembrane system
                                        part-ofendoplasmic reticulum
                                                part-ofendoplasmic reticulum part +
                                                is-amembrane stack
                                                is-aplasmodesmatal endoplasmic reticulum
                                                is-arough endoplasmic reticulum [GO:0005791] (67 genes, 67 annotations)
                                                        part-ofrough endoplasmic reticulum lumen
                                                        part-ofrough endoplasmic reticulum membrane +
                                                is-asarcoplasmic reticulum +
                                                is-asmooth endoplasmic reticulum +


Gene_Ontology
        is-acellular_component
                is-acell
                        part-ofcell part
                                is-aintracellular
                                        part-ofintracellular part
                                                is-acytoplasm
                                                        part-ofcytoplasmic part
                                                                is-aendoplasmic reticulum
                                                                        part-ofendoplasmic reticulum part +
                                                                        is-amembrane stack
                                                                        is-aplasmodesmatal endoplasmic reticulum
                                                                        is-arough endoplasmic reticulum [GO:0005791] (67 genes, 67 annotations)
                                                                                part-ofrough endoplasmic reticulum lumen
                                                                                part-ofrough endoplasmic reticulum membrane +
                                                                        is-asarcoplasmic reticulum +
                                                                        is-asmooth endoplasmic reticulum +


Gene_Ontology
        is-acellular_component
                is-acell
                        part-ofcell part
                                is-aintracellular
                                        part-ofintracellular part
                                                is-acytoplasmic part
                                                        is-aendoplasmic reticulum
                                                                part-ofendoplasmic reticulum part +
                                                                is-amembrane stack
                                                                is-aplasmodesmatal endoplasmic reticulum
                                                                is-arough endoplasmic reticulum [GO:0005791] (67 genes, 67 annotations)
                                                                        part-ofrough endoplasmic reticulum lumen
                                                                        part-ofrough endoplasmic reticulum membrane +
                                                                is-asarcoplasmic reticulum +
                                                                is-asmooth endoplasmic reticulum +


Gene_Ontology
        is-acellular_component
                is-acell
                        part-ofcell part
                                is-aintracellular
                                        part-ofintracellular part
                                                is-aintracellular organelle
                                                        is-aintracellular membrane-bounded organelle
                                                                is-aendoplasmic reticulum
                                                                        part-ofendoplasmic reticulum part +
                                                                        is-amembrane stack
                                                                        is-aplasmodesmatal endoplasmic reticulum
                                                                        is-arough endoplasmic reticulum [GO:0005791] (67 genes, 67 annotations)
                                                                                part-ofrough endoplasmic reticulum lumen
                                                                                part-ofrough endoplasmic reticulum membrane +
                                                                        is-asarcoplasmic reticulum +
                                                                        is-asmooth endoplasmic reticulum +


Gene_Ontology
        is-acellular_component
                is-acell
                        part-ofcell part
                                is-aintracellular part
                                        is-acytoplasm
                                                part-ofcytoplasmic part
                                                        is-aendoplasmic reticulum
                                                                part-ofendoplasmic reticulum part +
                                                                is-amembrane stack
                                                                is-aplasmodesmatal endoplasmic reticulum
                                                                is-arough endoplasmic reticulum [GO:0005791] (67 genes, 67 annotations)
                                                                        part-ofrough endoplasmic reticulum lumen
                                                                        part-ofrough endoplasmic reticulum membrane +
                                                                is-asarcoplasmic reticulum +
                                                                is-asmooth endoplasmic reticulum +


Gene_Ontology
        is-acellular_component
                is-acell
                        part-ofcell part
                                is-aintracellular part
                                        is-acytoplasmic part
                                                is-aendoplasmic reticulum
                                                        part-ofendoplasmic reticulum part +
                                                        is-amembrane stack
                                                        is-aplasmodesmatal endoplasmic reticulum
                                                        is-arough endoplasmic reticulum [GO:0005791] (67 genes, 67 annotations)
                                                                part-ofrough endoplasmic reticulum lumen
                                                                part-ofrough endoplasmic reticulum membrane +
                                                        is-asarcoplasmic reticulum +
                                                        is-asmooth endoplasmic reticulum +


Gene_Ontology
        is-acellular_component
                is-acell
                        part-ofcell part
                                is-aintracellular part
                                        is-aintracellular organelle
                                                is-aintracellular membrane-bounded organelle
                                                        is-aendoplasmic reticulum
                                                                part-ofendoplasmic reticulum part +
                                                                is-amembrane stack
                                                                is-aplasmodesmatal endoplasmic reticulum
                                                                is-arough endoplasmic reticulum [GO:0005791] (67 genes, 67 annotations)
                                                                        part-ofrough endoplasmic reticulum lumen
                                                                        part-ofrough endoplasmic reticulum membrane +
                                                                is-asarcoplasmic reticulum +
                                                                is-asmooth endoplasmic reticulum +


Gene_Ontology
        is-acellular_component
                is-acell part
                        is-aendomembrane system
                                part-ofendoplasmic reticulum
                                        part-ofendoplasmic reticulum part +
                                        is-amembrane stack
                                        is-aplasmodesmatal endoplasmic reticulum
                                        is-arough endoplasmic reticulum [GO:0005791] (67 genes, 67 annotations)
                                                part-ofrough endoplasmic reticulum lumen
                                                part-ofrough endoplasmic reticulum membrane +
                                        is-asarcoplasmic reticulum +
                                        is-asmooth endoplasmic reticulum +


Gene_Ontology
        is-acellular_component
                is-acell part
                        is-aintracellular
                                part-ofintracellular part
                                        is-acytoplasm
                                                part-ofcytoplasmic part
                                                        is-aendoplasmic reticulum
                                                                part-ofendoplasmic reticulum part +
                                                                is-amembrane stack
                                                                is-aplasmodesmatal endoplasmic reticulum
                                                                is-arough endoplasmic reticulum [GO:0005791] (67 genes, 67 annotations)
                                                                        part-ofrough endoplasmic reticulum lumen
                                                                        part-ofrough endoplasmic reticulum membrane +
                                                                is-asarcoplasmic reticulum +
                                                                is-asmooth endoplasmic reticulum +


Gene_Ontology
        is-acellular_component
                is-acell part
                        is-aintracellular
                                part-ofintracellular part
                                        is-acytoplasmic part
                                                is-aendoplasmic reticulum
                                                        part-ofendoplasmic reticulum part +
                                                        is-amembrane stack
                                                        is-aplasmodesmatal endoplasmic reticulum
                                                        is-arough endoplasmic reticulum [GO:0005791] (67 genes, 67 annotations)
                                                                part-ofrough endoplasmic reticulum lumen
                                                                part-ofrough endoplasmic reticulum membrane +
                                                        is-asarcoplasmic reticulum +
                                                        is-asmooth endoplasmic reticulum +


Gene_Ontology
        is-acellular_component
                is-acell part
                        is-aintracellular
                                part-ofintracellular part
                                        is-aintracellular organelle
                                                is-aintracellular membrane-bounded organelle
                                                        is-aendoplasmic reticulum
                                                                part-ofendoplasmic reticulum part +
                                                                is-amembrane stack
                                                                is-aplasmodesmatal endoplasmic reticulum
                                                                is-arough endoplasmic reticulum [GO:0005791] (67 genes, 67 annotations)
                                                                        part-ofrough endoplasmic reticulum lumen
                                                                        part-ofrough endoplasmic reticulum membrane +
                                                                is-asarcoplasmic reticulum +
                                                                is-asmooth endoplasmic reticulum +


Gene_Ontology
        is-acellular_component
                is-acell part
                        is-aintracellular part
                                is-acytoplasm
                                        part-ofcytoplasmic part
                                                is-aendoplasmic reticulum
                                                        part-ofendoplasmic reticulum part +
                                                        is-amembrane stack
                                                        is-aplasmodesmatal endoplasmic reticulum
                                                        is-arough endoplasmic reticulum [GO:0005791] (67 genes, 67 annotations)
                                                                part-ofrough endoplasmic reticulum lumen
                                                                part-ofrough endoplasmic reticulum membrane +
                                                        is-asarcoplasmic reticulum +
                                                        is-asmooth endoplasmic reticulum +


Gene_Ontology
        is-acellular_component
                is-acell part
                        is-aintracellular part
                                is-acytoplasmic part
                                        is-aendoplasmic reticulum
                                                part-ofendoplasmic reticulum part +
                                                is-amembrane stack
                                                is-aplasmodesmatal endoplasmic reticulum
                                                is-arough endoplasmic reticulum [GO:0005791] (67 genes, 67 annotations)
                                                        part-ofrough endoplasmic reticulum lumen
                                                        part-ofrough endoplasmic reticulum membrane +
                                                is-asarcoplasmic reticulum +
                                                is-asmooth endoplasmic reticulum +


Gene_Ontology
        is-acellular_component
                is-acell part
                        is-aintracellular part
                                is-aintracellular organelle
                                        is-aintracellular membrane-bounded organelle
                                                is-aendoplasmic reticulum
                                                        part-ofendoplasmic reticulum part +
                                                        is-amembrane stack
                                                        is-aplasmodesmatal endoplasmic reticulum
                                                        is-arough endoplasmic reticulum [GO:0005791] (67 genes, 67 annotations)
                                                                part-ofrough endoplasmic reticulum lumen
                                                                part-ofrough endoplasmic reticulum membrane +
                                                        is-asarcoplasmic reticulum +
                                                        is-asmooth endoplasmic reticulum +


Gene_Ontology
        is-acellular_component
                is-aorganelle
                        is-aintracellular organelle
                                is-aintracellular membrane-bounded organelle
                                        is-aendoplasmic reticulum
                                                part-ofendoplasmic reticulum part +
                                                is-amembrane stack
                                                is-aplasmodesmatal endoplasmic reticulum
                                                is-arough endoplasmic reticulum [GO:0005791] (67 genes, 67 annotations)
                                                        part-ofrough endoplasmic reticulum lumen
                                                        part-ofrough endoplasmic reticulum membrane +
                                                is-asarcoplasmic reticulum +
                                                is-asmooth endoplasmic reticulum +


Gene_Ontology
        is-acellular_component
                is-aorganelle
                        is-amembrane-bounded organelle
                                is-aintracellular membrane-bounded organelle
                                        is-aendoplasmic reticulum
                                                part-ofendoplasmic reticulum part +
                                                is-amembrane stack
                                                is-aplasmodesmatal endoplasmic reticulum
                                                is-arough endoplasmic reticulum [GO:0005791] (67 genes, 67 annotations)
                                                        part-ofrough endoplasmic reticulum lumen
                                                        part-ofrough endoplasmic reticulum membrane +
                                                is-asarcoplasmic reticulum +
                                                is-asmooth endoplasmic reticulum +


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last database update
07/23/2014
MGI 5.19
The Jackson Laboratory