Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Lipc

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes LIPC
- Mouse genes Lipc
- Rat genes Lipc
- Zfish genes lipca
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Lipc

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008126	acetylesterase activity	Lipc	IDA		Rat	PMID:1940628\|RGD:2308774
Molecular Function	GO:0047372	acylglycerol lipase activity	Lipc	IDA		Rat	PMID:6696938\|RGD:2308779
Molecular Function	GO:0016746	acyltransferase activity	Lipc	IDA		Rat	PMID:9048565\|RGD:2308766
Molecular Function	GO:0034185	apolipoprotein binding	Lipc	IDA		Rat	PMID:9685400\|RGD:2308763
Molecular Function	GO:0034185	apolipoprotein binding	Lipc	IPI	UniProtKB:P04114	Rat	PMID:9685400\|RGD:2308763
Molecular Function	GO:0035478	chylomicron binding	Lipc	IDA		Rat	PMID:9685400\|RGD:2308763
Molecular Function	GO:0043395	heparan sulfate proteoglycan binding	Lipc	IMP		Rat	PMID:15102889\|RGD:1580511
Molecular Function	GO:0008201	heparin binding	Lipc	IDA		Rat	PMID:10681410\|RGD:2307450
Molecular Function	GO:0042802	identical protein binding	Lipc	IPI	RGD:3009	Rat	PMID:9540793\|RGD:2308765
Molecular Function	GO:0016298	lipase activity	Lipc	IDA		Mouse	PMID:15995171
Molecular Function	GO:0016298	lipase activity	Lipc	IDA		Mouse	PMID:12975454
Molecular Function	GO:0008289	lipid binding	Lipc	IDA		Rat	PMID:1865764\|RGD:1600649
Molecular Function	GO:0030169	low-density lipoprotein particle binding	Lipc	IDA		Rat	PMID:8071607\|RGD:2308769
Molecular Function	GO:0030169	low-density lipoprotein particle binding	Lipc	IDA		Rat	PMID:9685400\|RGD:2308763
Molecular Function	GO:0004622	lysophospholipase activity	Lipc	IDA		Rat	PMID:1531641\|RGD:2308772
Molecular Function	GO:0008970	phospholipase A1 activity	LIPC	IDA		Human	PMID:12032167
Molecular Function	GO:0008970	phospholipase A1 activity	LIPC	IDA		Human	PMID:26193433
Molecular Function	GO:0008970	phospholipase A1 activity	LIPC	IDA		Human	PMID:7592706
Molecular Function	GO:0008970	phospholipase A1 activity	Lipc	IDA		Rat	PMID:1531641\|RGD:2308772
Molecular Function	GO:0008970	phospholipase A1 activity	Lipc	IDA		Rat	PMID:1770315\|RGD:25671398
Molecular Function	GO:0008970	phospholipase A1 activity	Lipc	IDA		Rat	PMID:1865764\|RGD:1600649
Molecular Function	GO:0008970	phospholipase A1 activity	Lipc	IDA		Rat	PMID:1940628\|RGD:2308774
Molecular Function	GO:0008970	phospholipase A1 activity	Lipc	IDA		Rat	PMID:6747460\|RGD:25671390
Molecular Function	GO:0008970	phospholipase A1 activity	Lipc	IDA		Rat	PMID:7074125\|RGD:25671392
Molecular Function	GO:0005515	protein binding	LIPC	IPI	UniProtKB:P02652	Human	PMID:14967812
Molecular Function	GO:0005515	protein binding	Lipc	IPI	PR:Q3U3R4	Mouse	PMID:19783858
Molecular Function	GO:0004806	triglyceride lipase activity	LIPC	IDA		Human	PMID:12032167
Molecular Function	GO:0004806	triglyceride lipase activity	LIPC	IDA		Human	PMID:182536
Molecular Function	GO:0004806	triglyceride lipase activity	LIPC	IDA		Human	PMID:26193433
Molecular Function	GO:0004806	triglyceride lipase activity	LIPC	IDA		Human	PMID:2839510
Molecular Function	GO:0004806	triglyceride lipase activity	LIPC	IDA		Human	PMID:7592706
Molecular Function	GO:0004806	triglyceride lipase activity	LIPC	IDA		Human	PMID:8798474
Molecular Function	GO:0004806	triglyceride lipase activity	Lipc	IDA		Rat	PMID:10734075\|RGD:1600640
Molecular Function	GO:0004806	triglyceride lipase activity	Lipc	IDA		Rat	PMID:15102889\|RGD:1580511
Molecular Function	GO:0004806	triglyceride lipase activity	Lipc	IDA		Rat	PMID:1531641\|RGD:2308772
Molecular Function	GO:0004806	triglyceride lipase activity	Lipc	IDA		Rat	PMID:1770315\|RGD:25671398
Molecular Function	GO:0004806	triglyceride lipase activity	Lipc	IDA		Rat	PMID:1865764\|RGD:1600649
Molecular Function	GO:0004806	triglyceride lipase activity	Lipc	IDA		Rat	PMID:1940628\|RGD:2308774
Molecular Function	GO:0004806	triglyceride lipase activity	Lipc	IDA		Rat	PMID:7074125\|RGD:25671392
Cellular Component	GO:0009986	cell surface	Lipc	IDA		Rat	PMID:384999\|RGD:2308777
Cellular Component	GO:0005769	early endosome	Lipc	IDA		Rat	PMID:14701798\|RGD:1625029
Cellular Component	GO:0005615	extracellular space	LIPC	IDA		Human	PMID:2839510
Cellular Component	GO:0005615	extracellular space	Lipc	IDA		Mouse	PMID:15995171
Cellular Component	GO:0005615	extracellular space	Lipc	IDA		Rat	PMID:18691644\|RGD:2307433
Cellular Component	GO:0005770	late endosome	Lipc	IDA		Rat	PMID:14701798\|RGD:1625029
Cellular Component	GO:0005902	microvillus	Lipc	IDA		Rat	PMID:9020876\|RGD:1600641
Biological Process	GO:0032870	cellular response to hormone stimulus	Lipc	IEP		Rat	PMID:12234100\|RGD:2307445
Biological Process	GO:0042632	cholesterol homeostasis	LIPC	IMP		Human	PMID:1883393
Biological Process	GO:0042632	cholesterol homeostasis	Lipc	IGI	MGI:MGI:88050	Mouse	PMID:10357838
Biological Process	GO:0008203	cholesterol metabolic process	Lipc	IGI	MGI:MGI:88050	Mouse	PMID:10357838
Biological Process	GO:0030301	cholesterol transport	Lipc	IMP	MGI:MGI:1857182	Mouse	PMID:8798380
Biological Process	GO:0034382	chylomicron remnant clearance	Lipc	IDA		Rat	PMID:8192680\|RGD:2308768
Biological Process	GO:0034371	chylomicron remodeling	Lipc	IDA		Rat	PMID:7897313\|RGD:2308767
Biological Process	GO:0007623	circadian rhythm	Lipc	IEP		Rat	PMID:9728079\|RGD:2307452
Biological Process	GO:0048589	developmental growth	Lipc	IEP		Rat	PMID:1391269\|RGD:2308773
Biological Process	GO:0006633	fatty acid biosynthetic process	LIPC	IDA		Human	PMID:182536
Biological Process	GO:0006631	fatty acid metabolic process	Lipc	IDA		Rat	PMID:10734075\|RGD:1600640
Biological Process	GO:0046475	glycerophospholipid catabolic process	Lipc	IDA		Rat	PMID:9048565\|RGD:2308766
Biological Process	GO:0015012	heparan sulfate proteoglycan biosynthetic process	Lipc	IDA		Rat	PMID:15102889\|RGD:1580511
Biological Process	GO:0034375	high-density lipoprotein particle remodeling	LIPC	IMP		Human	PMID:3244012
Biological Process	GO:0034375	high-density lipoprotein particle remodeling	Lipc	IDA		Rat	PMID:8157689\|RGD:2308770
Biological Process	GO:0001889	liver development	Lipc	IEP		Rat	PMID:11004003\|RGD:2307448
Biological Process	GO:0034383	low-density lipoprotein particle clearance	Lipc	IDA		Rat	PMID:8071607\|RGD:2308769
Biological Process	GO:0034374	low-density lipoprotein particle remodeling	LIPC	IMP		Human	PMID:3244012
Biological Process	GO:0034374	low-density lipoprotein particle remodeling	Lipc	IDA		Rat	PMID:8071607\|RGD:2308769
Biological Process	GO:0034374	low-density lipoprotein particle remodeling	Lipc	IDA		Rat	PMID:9685400\|RGD:2308763
Biological Process	GO:0046461	neutral lipid catabolic process	Lipc	IDA		Rat	PMID:1865764\|RGD:1600649
Biological Process	GO:0046473	phosphatidic acid metabolic process	Lipc	IDA		Rat	PMID:2223857\|RGD:1600650
Biological Process	GO:0046470	phosphatidylcholine metabolic process	Lipc	IDA		Rat	PMID:2223857\|RGD:1600650
Biological Process	GO:0046337	phosphatidylethanolamine metabolic process	Lipc	IDA		Rat	PMID:2223857\|RGD:1600650
Biological Process	GO:0006658	phosphatidylserine metabolic process	Lipc	IDA		Rat	PMID:2223857\|RGD:1600650
Biological Process	GO:0097006	regulation of plasma lipoprotein particle levels	Lipc	IMP		Rat	PMID:9822677\|RGD:2307451
Biological Process	GO:0010034	response to acetate	Lipc	IEP		Rat	PMID:11427199\|RGD:2307447
Biological Process	GO:0043200	response to amino acid	Lipc	IEP		Rat	PMID:19212806\|RGD:2307430
Biological Process	GO:0051592	response to calcium ion	Lipc	IEP		Rat	PMID:9480878\|RGD:2308764
Biological Process	GO:0009743	response to carbohydrate	Lipc	IEP		Rat	PMID:15744060\|RGD:2307443
Biological Process	GO:0046688	response to copper ion	Lipc	IEP		Rat	PMID:3420106\|RGD:2308778
Biological Process	GO:0070542	response to fatty acid	Lipc	IEP		Rat	PMID:2086700\|RGD:2308776
Biological Process	GO:0051384	response to glucocorticoid	Lipc	IEP		Rat	PMID:15271879\|RGD:2307444
Biological Process	GO:0009725	response to hormone	Lipc	IEP		Rat	PMID:8510508\|RGD:2307446
Biological Process	GO:0009725	response to hormone	lipca	IDA		Zfish	PMID:26308493
Biological Process	GO:0001666	response to hypoxia	Lipc	IEP		Rat	PMID:15271879\|RGD:2307444
Biological Process	GO:0010035	response to inorganic substance	Lipc	IEP		Rat	PMID:10823662\|RGD:2307449
Biological Process	GO:0033993	response to lipid	Lipc	IEP		Rat	PMID:17709442\|RGD:2307437
Biological Process	GO:0032026	response to magnesium ion	Lipc	IEP		Rat	PMID:2046484\|RGD:2308775
Biological Process	GO:0031667	response to nutrient levels	Lipc	IEP		Rat	PMID:19165521\|RGD:2307431
Biological Process	GO:0014070	response to organic cyclic compound	Lipc	IEP		Rat	PMID:18675312\|RGD:2307434
Biological Process	GO:0014070	response to organic cyclic compound	Lipc	IEP		Rat	PMID:9721028\|RGD:2307435
Biological Process	GO:0043434	response to peptide hormone	Lipc	IEP		Rat	PMID:16546477\|RGD:2307438
Biological Process	GO:0009410	response to xenobiotic stimulus	Lipc	IEP		Rat	PMID:8322779\|RGD:2308771
Biological Process	GO:0019433	triglyceride catabolic process	LIPC	IDA		Human	PMID:182536
Biological Process	GO:0019433	triglyceride catabolic process	LIPC	IDA		Human	PMID:2839510
Biological Process	GO:0019433	triglyceride catabolic process	LIPC	IDA		Human	PMID:8640403
Biological Process	GO:0070328	triglyceride homeostasis	LIPC	IMP		Human	PMID:1883393
Biological Process	GO:0006641	triglyceride metabolic process	Lipc	IDA		Rat	PMID:10734075\|RGD:1600640
Biological Process	GO:0034372	very-low-density lipoprotein particle remodeling	LIPC	IDA		Human	PMID:8640403
Biological Process	GO:0034372	very-low-density lipoprotein particle remodeling	Lipc	IDA		Rat	PMID:6791934\|RGD:2308780

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 05/14/2024 MGI 6.23

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.