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Gene Ontology Browser
Term Detail
GO term:cholesterol metabolic process
Synonym: cholesterol metabolism
GO id:GO:0008203
Definition:The chemical reactions and pathways involving cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones. It is a component of the plasma membrane lipid bilayer and of plasma lipoproteins and can be found in all animal tissues.
Number of paths to term: 8

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aorganic substance metabolic process
                                is-alipid metabolic process
                                        is-asteroid metabolic process
                                                is-asterol metabolic process
                                                        is-acholesterol metabolic process [GO:0008203] (105 genes, 155 annotations)
                                                                is-acholesterol biosynthetic process +
                                                                is-acholesterol catabolic process
                                                                is-acholesterol ester hydrolysis involved in cholesterol transport
                                                                negatively-regulatesnegative regulation of cholesterol metabolic process +
                                                                is-apeptidyl-glycine cholesteryl ester biosynthesis from peptidyl-glycine
                                                                positively-regulatespositive regulation of cholesterol metabolic process +
                                                                regulatesregulation of cholesterol metabolic process +
                                                        is-aecdysone metabolic process +
                                                        is-aergosterol metabolic process +
                                                        is-asterol acetylation
                                                        is-asterol biosynthetic process +
                                                        is-asterol catabolic process +
                                                        is-asterol deacetylation
                                                        is-azymosterol metabolic process +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aorganic substance metabolic process
                                is-aorganic cyclic compound metabolic process
                                        is-asteroid metabolic process
                                                is-asterol metabolic process
                                                        is-acholesterol metabolic process [GO:0008203] (105 genes, 155 annotations)
                                                                is-acholesterol biosynthetic process +
                                                                is-acholesterol catabolic process
                                                                is-acholesterol ester hydrolysis involved in cholesterol transport
                                                                negatively-regulatesnegative regulation of cholesterol metabolic process +
                                                                is-apeptidyl-glycine cholesteryl ester biosynthesis from peptidyl-glycine
                                                                positively-regulatespositive regulation of cholesterol metabolic process +
                                                                regulatesregulation of cholesterol metabolic process +
                                                        is-aecdysone metabolic process +
                                                        is-aergosterol metabolic process +
                                                        is-asterol acetylation
                                                        is-asterol biosynthetic process +
                                                        is-asterol catabolic process +
                                                        is-asterol deacetylation
                                                        is-azymosterol metabolic process +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aorganic substance metabolic process
                                is-aorganic hydroxy compound metabolic process
                                        is-aalcohol metabolic process
                                                is-asterol metabolic process
                                                        is-acholesterol metabolic process [GO:0008203] (105 genes, 155 annotations)
                                                                is-acholesterol biosynthetic process +
                                                                is-acholesterol catabolic process
                                                                is-acholesterol ester hydrolysis involved in cholesterol transport
                                                                negatively-regulatesnegative regulation of cholesterol metabolic process +
                                                                is-apeptidyl-glycine cholesteryl ester biosynthesis from peptidyl-glycine
                                                                positively-regulatespositive regulation of cholesterol metabolic process +
                                                                regulatesregulation of cholesterol metabolic process +
                                                        is-aecdysone metabolic process +
                                                        is-aergosterol metabolic process +
                                                        is-asterol acetylation
                                                        is-asterol biosynthetic process +
                                                        is-asterol catabolic process +
                                                        is-asterol deacetylation
                                                        is-azymosterol metabolic process +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aprimary metabolic process
                                is-alipid metabolic process
                                        is-asteroid metabolic process
                                                is-asterol metabolic process
                                                        is-acholesterol metabolic process [GO:0008203] (105 genes, 155 annotations)
                                                                is-acholesterol biosynthetic process +
                                                                is-acholesterol catabolic process
                                                                is-acholesterol ester hydrolysis involved in cholesterol transport
                                                                negatively-regulatesnegative regulation of cholesterol metabolic process +
                                                                is-apeptidyl-glycine cholesteryl ester biosynthesis from peptidyl-glycine
                                                                positively-regulatespositive regulation of cholesterol metabolic process +
                                                                regulatesregulation of cholesterol metabolic process +
                                                        is-aecdysone metabolic process +
                                                        is-aergosterol metabolic process +
                                                        is-asterol acetylation
                                                        is-asterol biosynthetic process +
                                                        is-asterol catabolic process +
                                                        is-asterol deacetylation
                                                        is-azymosterol metabolic process +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-asingle-organism metabolic process
                                is-alipid metabolic process
                                        is-asteroid metabolic process
                                                is-asterol metabolic process
                                                        is-acholesterol metabolic process [GO:0008203] (105 genes, 155 annotations)
                                                                is-acholesterol biosynthetic process +
                                                                is-acholesterol catabolic process
                                                                is-acholesterol ester hydrolysis involved in cholesterol transport
                                                                negatively-regulatesnegative regulation of cholesterol metabolic process +
                                                                is-apeptidyl-glycine cholesteryl ester biosynthesis from peptidyl-glycine
                                                                positively-regulatespositive regulation of cholesterol metabolic process +
                                                                regulatesregulation of cholesterol metabolic process +
                                                        is-aecdysone metabolic process +
                                                        is-aergosterol metabolic process +
                                                        is-asterol acetylation
                                                        is-asterol biosynthetic process +
                                                        is-asterol catabolic process +
                                                        is-asterol deacetylation
                                                        is-azymosterol metabolic process +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-asingle-organism metabolic process
                                is-asmall molecule metabolic process
                                        is-aalcohol metabolic process
                                                is-asterol metabolic process
                                                        is-acholesterol metabolic process [GO:0008203] (105 genes, 155 annotations)
                                                                is-acholesterol biosynthetic process +
                                                                is-acholesterol catabolic process
                                                                is-acholesterol ester hydrolysis involved in cholesterol transport
                                                                negatively-regulatesnegative regulation of cholesterol metabolic process +
                                                                is-apeptidyl-glycine cholesteryl ester biosynthesis from peptidyl-glycine
                                                                positively-regulatespositive regulation of cholesterol metabolic process +
                                                                regulatesregulation of cholesterol metabolic process +
                                                        is-aecdysone metabolic process +
                                                        is-aergosterol metabolic process +
                                                        is-asterol acetylation
                                                        is-asterol biosynthetic process +
                                                        is-asterol catabolic process +
                                                        is-asterol deacetylation
                                                        is-azymosterol metabolic process +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism metabolic process
                                is-alipid metabolic process
                                        is-asteroid metabolic process
                                                is-asterol metabolic process
                                                        is-acholesterol metabolic process [GO:0008203] (105 genes, 155 annotations)
                                                                is-acholesterol biosynthetic process +
                                                                is-acholesterol catabolic process
                                                                is-acholesterol ester hydrolysis involved in cholesterol transport
                                                                negatively-regulatesnegative regulation of cholesterol metabolic process +
                                                                is-apeptidyl-glycine cholesteryl ester biosynthesis from peptidyl-glycine
                                                                positively-regulatespositive regulation of cholesterol metabolic process +
                                                                regulatesregulation of cholesterol metabolic process +
                                                        is-aecdysone metabolic process +
                                                        is-aergosterol metabolic process +
                                                        is-asterol acetylation
                                                        is-asterol biosynthetic process +
                                                        is-asterol catabolic process +
                                                        is-asterol deacetylation
                                                        is-azymosterol metabolic process +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism metabolic process
                                is-asmall molecule metabolic process
                                        is-aalcohol metabolic process
                                                is-asterol metabolic process
                                                        is-acholesterol metabolic process [GO:0008203] (105 genes, 155 annotations)
                                                                is-acholesterol biosynthetic process +
                                                                is-acholesterol catabolic process
                                                                is-acholesterol ester hydrolysis involved in cholesterol transport
                                                                negatively-regulatesnegative regulation of cholesterol metabolic process +
                                                                is-apeptidyl-glycine cholesteryl ester biosynthesis from peptidyl-glycine
                                                                positively-regulatespositive regulation of cholesterol metabolic process +
                                                                regulatesregulation of cholesterol metabolic process +
                                                        is-aecdysone metabolic process +
                                                        is-aergosterol metabolic process +
                                                        is-asterol acetylation
                                                        is-asterol biosynthetic process +
                                                        is-asterol catabolic process +
                                                        is-asterol deacetylation
                                                        is-azymosterol metabolic process +


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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory