About   Help   FAQ
Gene Ontology Browser
Term Detail
GO term:high-density lipoprotein particle remodeling
Synonym: HDL remodeling
GO id:GO:0034375
Definition:The acquisition, loss or modification of a protein or lipid within a high-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase, with the subsequent loss of free fatty acid, and the transfer of cholesterol esters from LDL to a triglyceride-rich lipoprotein particle by cholesteryl ester transfer protein (CETP), with the simultaneous transfer of triglyceride to LDL.
Number of paths to term: 7

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of plasma lipoprotein particle levels
                                        part-ofplasma lipoprotein particle remodeling
                                                is-ahigh-density lipoprotein particle remodeling [GO:0034375] (9 genes, 10 annotations)
                                                        is-aconversion of discoidal high-density lipoprotein particle to spherical high-density lipoprotein particle
                                                is-alow-density lipoprotein particle remodeling
                                                is-atriglyceride-rich lipoprotein particle remodeling +


Gene_Ontology
        is-abiological_process
                is-acellular component organization or biogenesis
                        is-acellular component organization
                                is-amacromolecular complex subunit organization
                                        is-amacromolecular complex remodeling
                                                is-aprotein-lipid complex remodeling
                                                        is-aplasma lipoprotein particle remodeling
                                                                is-ahigh-density lipoprotein particle remodeling [GO:0034375] (9 genes, 10 annotations)
                                                                        is-aconversion of discoidal high-density lipoprotein particle to spherical high-density lipoprotein particle
                                                                is-alow-density lipoprotein particle remodeling
                                                                is-atriglyceride-rich lipoprotein particle remodeling +


Gene_Ontology
        is-abiological_process
                is-acellular component organization or biogenesis
                        is-acellular component organization
                                is-amacromolecular complex subunit organization
                                        is-aprotein-lipid complex subunit organization
                                                is-aplasma lipoprotein particle organization
                                                        is-aplasma lipoprotein particle remodeling
                                                                is-ahigh-density lipoprotein particle remodeling [GO:0034375] (9 genes, 10 annotations)
                                                                        is-aconversion of discoidal high-density lipoprotein particle to spherical high-density lipoprotein particle
                                                                is-alow-density lipoprotein particle remodeling
                                                                is-atriglyceride-rich lipoprotein particle remodeling +


Gene_Ontology
        is-abiological_process
                is-acellular component organization or biogenesis
                        is-acellular component organization
                                is-amacromolecular complex subunit organization
                                        is-aprotein-lipid complex subunit organization
                                                is-aprotein-lipid complex remodeling
                                                        is-aplasma lipoprotein particle remodeling
                                                                is-ahigh-density lipoprotein particle remodeling [GO:0034375] (9 genes, 10 annotations)
                                                                        is-aconversion of discoidal high-density lipoprotein particle to spherical high-density lipoprotein particle
                                                                is-alow-density lipoprotein particle remodeling
                                                                is-atriglyceride-rich lipoprotein particle remodeling +


Gene_Ontology
        is-abiological_process
                is-amulticellular organismal process
                        is-asingle-multicellular organism process
                                is-aplasma lipoprotein particle organization
                                        is-aplasma lipoprotein particle remodeling
                                                is-ahigh-density lipoprotein particle remodeling [GO:0034375] (9 genes, 10 annotations)
                                                        is-aconversion of discoidal high-density lipoprotein particle to spherical high-density lipoprotein particle
                                                is-alow-density lipoprotein particle remodeling
                                                is-atriglyceride-rich lipoprotein particle remodeling +


Gene_Ontology
        is-abiological_process
                regulatesregulation of biological process
                        is-aregulation of plasma lipoprotein particle levels
                                part-ofplasma lipoprotein particle remodeling
                                        is-ahigh-density lipoprotein particle remodeling [GO:0034375] (9 genes, 10 annotations)
                                                is-aconversion of discoidal high-density lipoprotein particle to spherical high-density lipoprotein particle
                                        is-alow-density lipoprotein particle remodeling
                                        is-atriglyceride-rich lipoprotein particle remodeling +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-multicellular organism process
                                is-aplasma lipoprotein particle organization
                                        is-aplasma lipoprotein particle remodeling
                                                is-ahigh-density lipoprotein particle remodeling [GO:0034375] (9 genes, 10 annotations)
                                                        is-aconversion of discoidal high-density lipoprotein particle to spherical high-density lipoprotein particle
                                                is-alow-density lipoprotein particle remodeling
                                                is-atriglyceride-rich lipoprotein particle remodeling +


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
09/23/2014
MGI 5.19
The Jackson Laboratory