| GO term: | heparan sulfate proteoglycan biosynthetic process |
| Synonym: | heparan sulfate proteoglycan anabolism |
| Synonym: | heparan sulfate proteoglycan biosynthesis |
| Synonym: | heparan sulfate proteoglycan formation |
| Synonym: | heparan sulfate proteoglycan synthesis |
| Synonym: | heparan sulphate proteoglycan biosynthesis |
| Synonym: | heparan sulphate proteoglycan biosynthetic process |
| Synonym: | heparin proteoglycan biosynthetic process |
| GO id: | GO:0015012 |
| Definition: | The chemical reactions and pathways resulting in the formation of the heparan sulfate proteoglycan, a glycosaminoglycan with repeat unit consisting of alternating alpha-(1->4)-linked hexuronic acid and glucosamine residues; the former are a mixture of sulfated and nonsulfated D-glucuronic acid and L-iduronic acid; the L-iduronic acid is either sulfated or acetylated on its amino group as well as being sulfated on one of its hydroxyl groups; heparan sulfate chains are covalently linked to peptidyl-serine by a glycosidic attachment through the trisaccharide galactosyl-galactosyl-xylosyl to serine residues. |
| Number of paths to term: | 40 |
denotes an 'is-a' relationship
denotes a 'part-of' relationship
denotes a 'regulates' relationship
denotes a 'positively-regulates' relationship
denotes a 'negatively-regulates' relationship
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc |
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last database update 05/08/2013 MGI 5.13 |
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