223 phenotypes from 36 alleles in 46 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Pkd1b2b1585Clo/Pkd1b2b1585Clo C57BL/6J-Pkd1b2b1585Clo	heart left ventricle hypertrophy	J:175213
	heart right ventricle hypertrophy	J:175213
	micrognathia	J:175213
	polycystic kidney	J:175213
Pkd1m1Bei/Pkd1m1Bei involves: A/J * FVB/N	edema	J:75360
	enlarged kidney	J:75360
	enlarged pancreas	J:75360
	kidney cyst	J:75360, J:213263
Pkd1tm1.1Bol/Pkd1tm1.1Bol Not Specified	no abnormal phenotype detected	J:148419
Pkd1tm1.1Djmp/Pkd1tm1.1Djmp involves: 129P2/OlaHsd * C57BL/6	no abnormal phenotype detected	J:94582
Pkd1tm1.1Djmp/Pkd1tm1.1Djmp Tg(Cdh16-cre/ERT2)F427Djmp/0 involves: 129P2/OlaHsd * C57BL/6 * C57BL/6NCrl * FVB/N	kidney cyst	J:130079
Pkd1tm1.1Djmp/Pkd1tm1.2Djmp Tg(Cdh16-cre/ERT2)F427Djmp/0 involves: 129P2/OlaHsd * C57BL/6 * C57BL/6NCrl * FVB/N	dilated renal tubule	J:130079
	increased kidney cell proliferation	J:130079
	increased kidney weight	J:130079
	kidney cyst	J:130079
	liver cyst	J:130079
	pale kidney	J:130079
	polycystic kidney	J:130079
Pkd1tm1.1Fqi/Pkd1tm1.1Fqi B6.129S6-Pkd1tm1.1Fqi	abnormal common bile duct morphology	J:127628
	dilated renal tubule	J:127628
	distended abdomen	J:127628
	enlarged kidney	J:127628
	increased blood urea nitrogen level	J:127628
	polycystic kidney	J:127628
	postnatal lethality	J:127628
	premature death	J:127628
	weight loss	J:127628
Pkd1tm1.1Fqi/Pkd1tm1.1Fqi involves: 129S6/SvEvTac	enlarged kidney	J:193175
	increased blood urea nitrogen level	J:193175
	increased circulating creatinine level	J:193175
	polycystic kidney	J:193175
Pkd1tm1.1Pcha/Pkd1tm1.1Pcha involves: 129S1/Sv * C57BL/6	abnormal kidney collecting duct morphology	J:193544
	dilated proximal convoluted tubule	J:193544
	enlarged kidney	J:193544
	increased blood urea nitrogen level	J:193544
	increased kidney weight	J:193544
	increased renal hamartoma incidence	J:193544
	polycystic kidney	J:193544
	renal fibrosis	J:193544
Pkd1tm1.1Pcha/Pkd1tm2Som Tg(Cdh16-cre)91Igr/0 involves: 129 * 129S4/SvJae * C57BL/6 * ICR	abnormal kidney physiology	J:244067
	abnormal peroxisome morphology	J:244067
	decreased fatty acid oxidation	J:244067
	increased circulating creatinine level	J:244067
	increased kidney cell proliferation	J:244067
	oxidative stress	J:244067
	polycystic kidney	J:244067
	premature death	J:244067
	renal interstitial fibrosis	J:244067
Pkd1tm1.2Bol/Pkd1tm1.2Bol Not Specified	prenatal lethality, complete penetrance	J:148419
Pkd1tm1.2Djmp/Pkd1+ involves: 129P2/OlaHsd * FVB/N	increased kidney cell proliferation	J:130079
Pkd1tm1.2Djmp/Pkd1tm1.2Djmp involves: 129P2/OlaHsd * FVB/N	prenatal lethality, complete penetrance	J:130079
Pkd1tm1b(EUCOMM)Hmgu/Pkd1+ C57BL/6N-Pkd1tm1b(EUCOMM)Hmgu/Bay	decreased circulating alkaline phosphatase level	J:211773
	decreased circulating total protein level	J:211773
	decreased erythrocyte cell number	J:211773
	decreased hematocrit	J:211773
	increased neutrophil cell number	J:211773
Pkd1tm1b(EUCOMM)Hmgu/Pkd1tm1b(EUCOMM)Hmgu C57BL/6N-Pkd1tm1b(EUCOMM)Hmgu/Bay	preweaning lethality, complete penetrance	J:211773
Pkd1tm1Bdgz/Pkd1+ involves: 129S1/Sv * 129X1/SvJ	dilated renal tubule	J:130086
	kidney cyst	J:130086
	liver cyst	J:130086
	pancreas cyst	J:130086
Pkd1tm1Bdgz/Pkd1tm1Bdgz involves: 129S1/Sv * 129X1/SvJ	kidney cyst	J:130086
	lethality throughout fetal growth and development, complete penetrance	J:130086
	pancreas cyst	J:130086
	skin edema	J:130086
Pkd1tm1Djmp/Pkd1tm1Djmp involves: 129P2/OlaHsd * C57BL/6	aortic aneurysm	J:94582
	aortic dissection	J:94582
	biliary cyst	J:94582
	decreased body weight	J:94582
	dilated bile duct	J:94582
	distended abdomen	J:94582
	kidney cyst	J:94582
	kidney inflammation	J:94582
	pancreas cyst	J:94582
	postnatal growth retardation	J:94582
	premature death	J:94582
	renal interstitial fibrosis	J:94582
Pkd1tm1Fqi/Pkd1tm1Fqi involves: 129S6/SvEvTac * C57BL/6	prenatal lethality, complete penetrance	J:127628
Pkd1tm1Ggg/Pkd1tm1Ggg either: (involves: 129/Sv) or (involves: 129/Sv * Black Swiss)	abnormal amniotic fluid composition	J:104483
	polyhydramnios	J:104483
Pkd1tm1Ggg/Pkd1tm1Ggg involves: 129/Sv * Black Swiss	edema	J:103719
	hemorrhage	J:103719
	polyhydramnios	J:103719
	prenatal lethality, complete penetrance	J:103719
Pkd1tm1Ggg/Pkd1tm1Ggg involves: 129S4/SvJae * C57BL/6	abnormal placenta development	J:165114
	abnormal placenta morphology	J:165114
	abnormal placenta vasculature	J:165114
	lethality throughout fetal growth and development, incomplete penetrance	J:165114
	polyhydramnios	J:165114
Pkd1tm1Ggg/Pkd1tm1Ggg Not Specified	kidney cyst	J:76062
	lethality throughout fetal growth and development, complete penetrance	J:76062
	pancreas cyst	J:76062
Pkd1tm1Ggg/Pkd1tm2.1Ggg involves: 129S4/SvJae * Black Swiss * C57BL/6	edema	J:103719
	hemorrhage	J:103719
	polyhydramnios	J:103719
	prenatal lethality, complete penetrance	J:103719
Pkd1tm1Ggg/Pkd1tm2Ggg Meox2tm1(cre)Sor/Meox2+ involves: 129S4/SvJae * 129S4/SvJaeSor	abnormal placenta morphology	J:165114
	abnormal placenta vasculature	J:165114
	normal cardiovascular system phenotype	J:165114
	edema	J:165114
	kidney cyst	J:165114
	lethality throughout fetal growth and development, incomplete penetrance	J:165114
	neonatal lethality, complete penetrance	J:165114
	polyhydramnios	J:165114
	respiratory failure	J:165114
Pkd1tm1Ggg/Pkd1tm2Ggg Tg(Col1a1-cre)1Bek/0 involves: 129S4/SvJae * CD-1	abnormal bone mineralization	J:191967
	decreased bone mineral density	J:191967
	decreased compact bone thickness	J:191967
	decreased trabecular bone volume	J:191967
	perinatal lethality	J:191967
	short femur	J:191967
Pkd1tm1Ggg/Pkd1tm2Ggg Tg(Tek-cre)1Ywa/0 involves: 129S4/SvJae * C57BL/6 * SJL	abnormal placenta vasculature	J:165114
	hemorrhage	J:165114
	normal homeostasis/metabolism phenotype	J:165114
	perinatal lethality, incomplete penetrance	J:165114
	polyhydramnios	J:165114
Pkd1tm1Gztn/Pkd1tm1Gztn Gt(ROSA)26Sortm9(cre/ESR1)Arte/Gt(ROSA)26Sor+ involves: 129S/Sv * 129S7/SvEvBrd * C57BL/6	abnormal kidney physiology	J:162080
	polycystic kidney	J:162080
Pkd1tm1Hung/Pkd1tm1Hung either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129P2/OlaHsd * FVB)	abnormal kidney morphology	J:104361
	abnormal skeleton development	J:104361
	normal cardiovascular system phenotype	J:104361
	decreased body size	J:104361
	decreased body weight	J:104361
	distended abdomen	J:104361
	enlarged kidney	J:104361
	increased blood urea nitrogen level	J:104361
	infertility	J:104361
	kidney cyst	J:104361
	normal liver/biliary system phenotype	J:104361
	pancreas cyst	J:104361
	postnatal growth retardation	J:104361
	premature death	J:104361
	renal interstitial fibrosis	J:104361
	normal respiratory system phenotype	J:104361
Pkd1tm1Jzh/Pkd1+ either: (involves: 129S4/SvJae * C57BL/6) or (involves: 129S4/SvJae * BALB/c)	abnormal bile duct morphology	J:52573
	abnormal circulating creatinine level	J:52573
	abnormal exocrine pancreas morphology	J:72627
	abnormal pancreatic acinus morphology	J:72627
	bile duct inflammation	J:52573
	decreased liver function	J:52573
	decreased pancreatic islet number	J:72627
	dilated pancreatic duct	J:72627
	dilated renal tubule	J:52573
	dissociated hepatocytes	J:52573
	exocrine pancreas atrophy	J:72627
	normal homeostasis/metabolism phenotype	J:52573
	kidney cyst	J:52573
	kidney inflammation	J:52573
	liver cyst	J:52573
	pancreas cyst	J:72627
	pancreas fibrosis	J:72627
	pancreas lipomatosis	J:72627
	renal interstitial fibrosis	J:52573
	normal renal/urinary system phenotype	J:43193
Pkd1tm1Jzh/Pkd1tm1Jzh either: (involves: 129S4/SvJae * C57BL/6) or (involves: 129S4/SvJae * BALB/c)	abnormal bone mineralization	J:72627
	abnormal kidney epithelial cell primary cilium physiology	J:81443
	abnormal kidney epithelium morphology	J:81443
	abnormal thyroid cartilage morphology	J:72627
	normal cardiovascular system phenotype	J:72627
	chondrodystrophy	J:72627
	decreased pancreatic islet number	J:43193
	dilated pancreatic duct	J:43193
	dilated proximal convoluted tubule	J:43193
	disproportionate dwarf	J:43193, J:72627
	distended abdomen	J:43193
	normal endocrine/exocrine gland phenotype	J:43193
	enlarged kidney	J:43193
	normal hematopoietic system phenotype	J:72627
	hydrops fetalis	J:72627
	kidney cortex cyst	J:43193
	kidney cyst	J:43193, J:81443
	kidney medulla cyst	J:43193
	normal liver/biliary system phenotype	J:43193
	pancreas cyst	J:43193
	perinatal lethality, incomplete penetrance	J:43193
	polyhydramnios	J:72627
	postnatal lethality, complete penetrance	J:43193
	pulmonary hypoplasia	J:43193
	normal renal/urinary system phenotype	J:43193
	respiratory distress	J:43193
	skin edema	J:72627
	small lung	J:43193
	spina bifida occulta	J:72627
Pkd1tm1Maa/Pkd1tm1Maa involves: 129S4/SvJae * C57BL/6	abnormal blood vessel morphology	J:68331
	hemorrhage	J:68331
	hydrops fetalis	J:68331
	kidney cyst	J:68331
	lethality throughout fetal growth and development, complete penetrance	J:68331
	pancreas cyst	J:68331
	skin edema	J:68331
Pkd1tm1Rsa/Pkd1+ involves: 129S4/SvJaeSor	kidney cyst	J:72238
	liver cyst	J:72238
Pkd1tm1Rsa/Pkd1tm1Rsa involves: 129S4/SvJaeSor	abnormal cartilage development	J:72238
	abnormal conotruncal ridge morphology	J:72238
	abnormal craniofacial bone morphology	J:72238
	abnormal Meckel's cartilage morphology	J:72238
	abnormal myocardial trabeculae morphology	J:72238
	abnormal radius morphology	J:72238
	abnormal spine curvature	J:72238
	abnormal ulna morphology	J:72238
	abnormal vertebrae morphology	J:72238
	atrial septal defect	J:72238
	common atrioventricular valve	J:72238
	decreased length of long bones	J:72238
	double outlet right ventricle	J:72238
	edema	J:72238
	failure of atrioventricular cushion closure	J:72238
	hemopericardium	J:72238
	hemorrhage	J:72238
	lethality throughout fetal growth and development, complete penetrance	J:72238
	thin myocardium	J:72238
	ventricular septal defect	J:72238
Pkd1tm1Shh/Pkd1tm1.1Pcha involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6	decreased bone mineral density	J:193544
	decreased compact bone mass	J:193544
	decreased trabecular bone mass	J:193544
	enlarged kidney	J:193544
	heart left ventricle hypertrophy	J:193544
	increased activity of parathyroid	J:193544
	increased blood urea nitrogen level	J:193544
	increased cell proliferation	J:193544
	increased heart weight	J:193544
	increased kidney epithelial cell primary cilium length	J:193544
	increased kidney weight	J:193544
	kidney failure	J:193544
	polycystic kidney	J:193544
	premature death	J:193544
	renal fibrosis	J:193544
	thick myocardium	J:193544
	uremia	J:193544
Pkd1tm1Shh/Pkd1tm1Shh involves: 129P2/OlaHsd * C57BL/6J	double outlet right ventricle	J:77927
	kidney cyst	J:77927
	lethality throughout fetal growth and development, incomplete penetrance	J:77927
	skin edema	J:77927
Pkd1tm1Som/Pkd1+ involves: 129/Sv * C57BL/6 * SJL	kidney cyst	J:78422
Pkd1tm1Som/Pkd1+ Tg(Pkd1*)39Mtru/0 involves: 129/Sv * C57BL/6J * CBA/J * SJL	dilated renal tubule	J:198147
	polycystic kidney	J:198147
Pkd1tm1Som/Pkd1tm1Som involves: 129/Sv * C57BL/6 * SJL	normal cardiovascular system phenotype	J:78422
	decreased embryo size	J:78422
	edema	J:78422
	embryonic lethality during organogenesis, incomplete penetrance	J:78422
	hemorrhage	J:78422
	kidney cyst	J:78422
	neonatal lethality, complete penetrance	J:78422
	pallor	J:78422
	pancreas cyst	J:78422
Pkd1tm1Som/Pkd1tm2Som Tg(Cdh16-cre/ERT2)24Igr/? involves: 129/Sv * C57BL/6 * SJL	abnormal mitotic spindle morphology	J:185863
Pkd1tm2.1Bol/Pkd1tm2.1Bol involves: 129S2/SvPas * C57BL/6 * C57BL/6NTac	no abnormal phenotype detected	J:153606
Pkd1tm2.1Bol/Pkd1tm2.2Bol involves: 129S2/SvPas * C57BL/6 * C57BL/6NTac	no abnormal phenotype detected	J:153606
Pkd1tm2.1Bol/Pkd1tm3.2Bol involves: 129S2/SvPas * C57BL/6 * C57BL/6NTac	no abnormal phenotype detected	J:153606
Pkd1tm2.1Ggg/Pkd1tm2.1Ggg involves: 129S4/SvJae * Black Swiss * C57BL/6	abnormal fluid regulation	J:103719
	hemorrhage	J:103719
	kidney cyst	J:103719
	pancreas cyst	J:103719
	prenatal lethality, complete penetrance	J:103719
Pkd1tm2.1Som/Pkd1tm2.1Som involves: C57BL/6 * FVB/N * SJL	embryonic lethality during organogenesis	J:135301
Pkd1tm2.2Bol/Pkd1tm2.2Bol involves: 129S2/SvPas * C57BL/6 * C57BL/6NTac	abnormal brain vasculature morphology	J:153606
	dilated lateral ventricle	J:153606
	dilated third ventricle	J:153606
	edema	J:153606
	hemorrhage	J:153606
	hydrocephaly	J:153606
	kidney cyst	J:153606
	lethality throughout fetal growth and development, complete penetrance	J:153606
Pkd1tm2.2Bol/Pkd1tm3.1Bol involves: 129S2/SvPas * C57BL/6 * C57BL/6NTac	no abnormal phenotype detected	J:153606
Pkd1tm2.2Bol/Pkd1tm3.1Bol Tg(Nes-cre)1Kln/0 involves: 129S2/SvPas * C57BL/6 * C57BL/6NTac * SJL	abnormal brain ventricle morphology	J:153606
	dilated lateral ventricle	J:153606
	dilated third ventricle	J:153606
	hydrocephaly	J:153606
	kidney cyst	J:153606
	kidney failure	J:153606
	postnatal lethality, complete penetrance	J:153606
Pkd1tm2Ggg/Pkd1+ Tg(Col1a1-cre)1Bek/0 involves: 129S4/SvJae * CD-1	decreased bone mineral density	J:191967
	decreased bone mineralization	J:191967
	decreased compact bone thickness	J:191967
	decreased trabecular bone volume	J:191967
	normal endocrine/exocrine gland phenotype	J:191967
	impaired osteoblast differentiation	J:191967
	increased osteoblast proliferation	J:191967
	normal renal/urinary system phenotype	J:191967
Pkd1tm2Ggg/Pkd1+ Tg(Pax8-rtTA2S*M2)1Koes/0 Tg(tetO-cre)1Jaw/0 involves: 129S4/SvJae * C57BL/6 * C57BL/6N * DBA * SJL	normal renal/urinary system phenotype	J:284006
Pkd1tm2Ggg/Pkd1tm2Ggg Gt(ROSA)26Sortm1(cre/ERT)Nat/Gt(ROSA)26Sor+ involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6	increased kidney weight	J:213263
Pkd1tm2Ggg/Pkd1tm2Ggg Tg(Col1a1-cre)1Bek/0 involves: 129S4/SvJae * CD-1	abnormal adipose tissue development	J:191967
	abnormal bone marrow morphology	J:191967
	abnormal circulating mineral level	J:191967
	abnormal exocrine pancreas morphology	J:191967
	abnormal osteoblast differentiation	J:191967
	decreased body size	J:191967
	decreased body weight	J:191967
	decreased bone mineral density	J:191967
	decreased bone mineralization	J:191967
	decreased compact bone thickness	J:191967
	decreased trabecular bone volume	J:191967
	increased blood urea nitrogen level	J:191967
	increased circulating parathyroid hormone level	J:191967
	increased osteoblast proliferation	J:191967
	pancreas cyst	J:191967
	polycystic kidney	J:191967
	postnatal lethality, incomplete penetrance	J:191967
	premature death	J:191967
	renal fibrosis	J:191967
	short femur	J:191967
Pkd1tm2Ggg/Pkd1tm2Ggg Tg(Hoxb7-cre)13Amc/0 involves: 129S4/SvJae * C57BL/6	increased blood urea nitrogen level	J:171619
	increased kidney apoptosis	J:171619
	increased kidney cell proliferation	J:171619
	polycystic kidney	J:171619
Pkd1tm2Ggg/Pkd1tm2Ggg Tg(MMTV-cre)4Mam/0 involves: 129S4/SvJae * FVB	kidney cyst	J:103719
	liver cyst	J:103719
Pkd1tm2Ggg/Pkd1tm2Ggg Tg(Nes-cre)Wme/0 involves: 129S4/SvJae * C57BL/6 * CBA	abnormal kidney morphology	J:185855
	enlarged kidney	J:185855
	increased blood urea nitrogen level	J:185855
	increased kidney apoptosis	J:185855
	increased kidney cell proliferation	J:185855
	kidney cyst	J:185855
	renal fibrosis	J:185855
Pkd1tm2Ggg/Pkd1tm2Ggg Tg(Pax8-rtTA2S*M2)1Koes/0 Tg(tetO-cre)1Jaw/0 involves: 129S4/SvJae * C57BL/6 * C57BL/6N * DBA * SJL	increased blood urea nitrogen level	J:284006
	increased kidney weight	J:284006
	polycystic kidney	J:284006
Pkd1tm2Jzh/Pkd1+ either: (involves: 129S4/SvJae * BALB/c) or (involves: 129S4/SvJae * C57BL/6)	kidney cyst	J:72627
	liver cyst	J:72627
	pancreas cyst	J:72627
Pkd1tm2Jzh/Pkd1tm2Jzh either: (involves: 129S4/SvJae * BALB/c) or (involves: 129S4/SvJae * C57BL/6)	abnormal bone marrow cavity morphology	J:72627
	abnormal bone mineralization	J:72627
	abnormal skeleton development	J:72627
	abnormal thyroid cartilage morphology	J:72627
	chondrodystrophy	J:72627
	decreased length of long bones	J:72627
	decreased width of hypertrophic chondrocyte zone	J:72627
	delayed endochondral bone ossification	J:72627
	delayed intramembranous bone ossification	J:72627
	disproportionate dwarf	J:72627
	hydrops fetalis	J:72627
	lethality throughout fetal growth and development, incomplete penetrance	J:72627
	pancreas cyst	J:72627
	perinatal lethality, complete penetrance	J:72627
	polycystic kidney	J:72627
	polyhydramnios	J:72627
	skin edema	J:72627
	spina bifida occulta	J:72627
Pkd1tm2Jzh/Pkd1tm2Jzh involves: 129S4/SvJae * C57BL/6	edema	J:140012
	lethality throughout fetal growth and development, incomplete penetrance	J:140012
	neonatal lethality, complete penetrance	J:140012
	polycystic kidney	J:140012
	polyhydramnios	J:140012
Pkd1tm2Pcha/Pkd1tm2Pcha involves: C57BL/6	lethality, complete penetrance	J:220561
Pkd1tm2Som/Pkd1tm2.1Som Tg(Cdh16-cre)91Igr/0 involves: C57BL/6 * ICR * SJL	abnormal kidney morphology	J:135301
	decreased circulating glucose level	J:135301
	increased blood urea nitrogen level	J:135301
	increased circulating cholesterol level	J:135301
	increased circulating phosphate level	J:135301
	increased kidney weight	J:135301
	kidney failure	J:135301
	polycystic kidney	J:135301
	postnatal lethality, complete penetrance	J:135301
Pkd1tm2Som/Pkd1tm2Som Tg(Cdh16-cre)91Igr/0 involves: 129S4/SvJae * C57BL/6 * ICR	increased circulating creatinine level	J:244067
	increased kidney cell proliferation	J:244067
	polycystic kidney	J:244067
	postnatal lethality, complete penetrance	J:244067
Pkd1tm2Som/Pkd1tm2Som Tg(Cdh16-cre)91Igr/0 involves: C57BL/6 * ICR * SJL	abnormal kidney morphology	J:135301
	decreased circulating glucose level	J:135301
	increased blood urea nitrogen level	J:135301
	increased circulating cholesterol level	J:135301
	increased circulating phosphate level	J:135301
	increased kidney weight	J:135301
	kidney failure	J:135301
	polycystic kidney	J:135301
	postnatal lethality, complete penetrance	J:135301
Pkd1tm2Som/Pkd1tm2Som Tg(Pkhd1-cre)1Igr/0 involves: C57BL/6 * SJL	abnormal kidney morphology	J:135301
	kidney cyst	J:135301
Pkd1tm3.1Bol/Pkd1tm3.1Bol involves: 129S2/SvPas * C57BL/6 * C57BL/6NTac	no abnormal phenotype detected	J:153606
Pkd1tm3.1Bol/Pkd1tm3.2Bol involves: 129S2/SvPas * C57BL/6 * C57BL/6NTac	no abnormal phenotype detected	J:153606
Pkd1tm3.1Jzh/Pkd1tm3.1Jzh involves: 129P2/OlaHsd * C57BL/6	edema	J:140012
	neonatal lethality, complete penetrance	J:140012
	polycystic kidney	J:140012
	polyhydramnios	J:140012
	prenatal lethality, incomplete penetrance	J:140012
Pkd1tm3.2Bol/Pkd1tm3.2Bol involves: 129S2/SvPas * C57BL/6 * C57BL/6NTac	abnormal brain vasculature morphology	J:153606
	dilated lateral ventricle	J:153606
	dilated third ventricle	J:153606
	edema	J:153606
	hemorrhage	J:153606
	hydrocephaly	J:153606
	kidney cyst	J:153606
	lethality throughout fetal growth and development, complete penetrance	J:153606
Pkd1tm3Jzh/Pkd1tm3Jzh involves: 129P2/OlaHsd * 129X1/SvJ	abnormal basicranium morphology	J:139970
	abnormal sphenoid bone morphology	J:139970
	abnormal sphenooccipital synchondrosis	J:139970
	decreased chondrocyte proliferation	J:139970
	delayed bone ossification	J:139970
	domed cranium	J:139970
	polycystic kidney	J:139970
	premature presphenoid synchondrosis closure	J:139970
	premature sphenooccipital synchondrosis closure	J:139970
	short presphenoid bone	J:139970
	slow postnatal weight gain	J:139970
Pkd1tm3Jzh/Pkd1tm3Jzh H2az2Tg(Wnt1-cre)11Rth/H2az2+ involves: 129P2/OlaHsd * C57BL/6 * CBA	abnormal craniofacial bone morphology	J:139970
	abnormal perichondrium morphology	J:139970
	abnormal presphenoid synchondrosis	J:139970
	abnormal sphenoid bone morphology	J:139970
	decreased chondrocyte proliferation	J:139970
	delayed intramembranous bone ossification	J:139970
	domed cranium	J:139970
	malocclusion	J:139970
	maxilla hypoplasia	J:139970
	nasal bone hypoplasia	J:139970
	premature presphenoid synchondrosis closure	J:139970
	short frontal bone	J:139970
	short mandible	J:139970
	short maxilla	J:139970
	short nasal bone	J:139970
	short premaxilla	J:139970
	short presphenoid bone	J:139970
	short snout	J:139970
Pkd1tm3Jzh/Pkd1tm3Jzh Tg(Col2a1-cre)10Amc/0 involves: 129P2/OlaHsd	abnormal compact bone morphology	J:140779
	delayed intramembranous bone ossification	J:140779
	polycystic kidney	J:140779
	postnatal lethality, complete penetrance	J:140779
	premature cranial synchondrosis closure	J:140779
Pkd1tm3Jzh/Pkd1tm3Jzh Tg(Ggt1-cre)M3Egn/0 involves: 129P2/OlaHsd * C57BL/6 * SJL	increased renal tubule apoptosis	J:140012
	polycystic kidney	J:140012
	premature death	J:140012
Pkd1tm3Jzh/Pkd1tm3Jzh Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/? involves: 129P2/OlaHsd * CD-1	delayed intramembranous bone ossification	J:139970
Tg(Pkd1)6Mtru/0 involves: C57BL/6J * CBA/J	abnormal aortic valve cusp morphology	J:157952
	abnormal renal tubule epithelium morphology	J:157952
	cardiac hypertrophy	J:157952
	decreased hematocrit	J:157952
	decreased urine creatinine level	J:157952
	decreased urine urea nitrogen level	J:157952
	dilated heart	J:157952
	dilated renal tubule	J:157952
	glomerulosclerosis	J:157952
	heart left ventricle hypertrophy	J:157952
	hematuria	J:157952
	increased blood osmolality	J:157952
	increased cardiac muscle contractility	J:157952
	increased circulating sodium level	J:157952
	increased heart weight	J:157952
	increased hepatocyte proliferation	J:157952
	increased kidney cell proliferation	J:157952
	increased urine osmolality	J:157952
	increased urine protein level	J:157952
	kidney cortex cyst	J:157952
	kidney cyst	J:157952
	kidney epithelium hyperplasia	J:157952
	kidney medulla cyst	J:157952
	liver cyst	J:157952
	liver fibrosis	J:157952
	nephrocalcinosis	J:157952
	nephrolithiasis	J:157952
	pale kidney	J:157952
	polyuria	J:157952
	premature death	J:157952
	renal cast	J:157952
	renal interstitial fibrosis	J:157952
	thick interventricular septum	J:157952
	thick ventricular wall	J:157952
Tg(Pkd1)18Mtru/0 involves: C57BL/6J * CBA/J	cardiac fibrosis	J:157952
	decreased hematocrit	J:157952
	glomerulosclerosis	J:157952
	hypertension	J:157952
	increased urine protein level	J:157952
	kidney cortex cyst	J:157952
	kidney cyst	J:157952
	kidney medulla cyst	J:157952
	nephrocalcinosis	J:157952
	nephrolithiasis	J:157952
	pale kidney	J:157952
	premature death	J:157952
Tg(Pkd1)26Mtru/0 involves: C57BL/6J * CBA/J	abnormal aortic valve cusp morphology	J:157952
	abnormal cerebellum development	J:157952
	abnormal myocardium layer morphology	J:157952
	abnormal renal tubule epithelium morphology	J:157952
	abnormal sagittal suture morphology	J:157952
	aneurysm	J:157952
	aortic valve stenosis	J:157952
	calcified aortic valve	J:157952
	cardiac fibrosis	J:157952
	cardiac hypertrophy	J:157952
	decreased hematocrit	J:157952
	decreased urine protein level	J:157952
	dilated brain ventricle	J:157952
	dilated heart	J:157952
	dilated renal tubule	J:157952
	dystrophic cardiac calcinosis	J:157952
	glomerulosclerosis	J:157952
	heart left ventricle hypertrophy	J:157952
	hematuria	J:157952
	hydrocephaly	J:157952
	hypertension	J:157952
	increased blood osmolality	J:157952
	increased cardiac output	J:157952
	increased cardiac stroke volume	J:157952
	increased circulating phosphate level	J:157952
	increased circulating sodium level	J:157952
	increased heart weight	J:157952
	increased hepatocyte proliferation	J:157952
	increased kidney cell proliferation	J:157952
	increased urine protein level	J:157952
	kidney cortex cyst	J:157952
	kidney cyst	J:157952
	kidney epithelium hyperplasia	J:157952
	kidney medulla cyst	J:157952
	liver cyst	J:157952
	liver fibrosis	J:157952
	nephrocalcinosis	J:157952
	nephrolithiasis	J:157952
	pale kidney	J:157952
	polyuria	J:157952
	premature death	J:157952
	renal cast	J:157952
	renal interstitial fibrosis	J:157952
	small cerebellum	J:157952
	subarachnoid hemorrhage	J:157952
	thick interventricular septum	J:157952
	thick ventricular wall	J:157952
Tg(Pkd1*)39Mtru/0 involves: C57BL/6J * CBA/J	abnormal ion homeostasis	J:198147
	abnormal renal glomerulus morphology	J:198147
	decreased hematocrit	J:198147
	decreased urine creatinine level	J:198147
	decreased urine osmolality	J:198147
	decreased urine urea nitrogen level	J:198147
	dilated renal tubule	J:198147
	increased blood urea nitrogen level	J:198147
	increased circulating creatinine level	J:198147
	increased urine protein level	J:198147
	kidney failure	J:198147
	pale kidney	J:198147
	polycystic kidney	J:198147
	polyuria	J:198147
	premature death	J:198147
	renal glomerulus cyst	J:198147
	renal interstitial fibrosis	J:198147
	renal tubule atrophy	J:198147