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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Jag1
jagged 1
MGI:1095416
121 phenotypes from 12 alleles in 21 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Jag1Gt(betageo)1Byg/Jag1+
involves: 129P2/OlaHsd * C57BL/6
no abnormal phenotype detected J:146621
Jag1Mhdahtu/Jag1+
C3HeB/FeJ-Jag1Mhdahtu
abnormal cochlear hair cell morphology J:72108
abnormal crista ampullaris morphology J:72108, J:149467
abnormal organ of Corti morphology J:72108
abnormal semicircular canal ampulla morphology J:72108
abnormal semicircular canal morphology J:72108
decreased cochlear outer hair cell number J:72108
head shaking J:72108
head tossing J:86685
normal hearing/vestibular/ear phenotype J:72108
increased cochlear inner hair cell number J:72108
Jag1Mhdahtu/Jag1Mhdahtu
C3HeB/FeJ-Jag1Mhdahtu
abnormal blood vessel morphology J:72108
abnormal vitelline vasculature morphology J:72108
embryonic growth retardation J:72108
embryonic lethality during organogenesis, complete penetrance J:72108
enlarged pericardium J:72108
hemorrhage J:72108
kinked neural tube J:72108
Jag1Mhdahtu/Jag1Slalom
involves: BALB/c * C3H * C3HeB/FeJ
abnormal vitelline vasculature morphology J:72108
embryo tissue necrosis J:72108
embryonic lethality during organogenesis J:72108
hemorrhage J:72108
Jag1Ndr/Jag1+
involves: C3H
head bobbing J:156172
impaired balance J:156172
Jag1Ndr/Jag1Ndr
involves: C3H
abnormal neuron differentiation J:156172
decreased neuronal precursor cell number J:156172
embryonic lethality during organogenesis, complete penetrance J:156172
increased neuron number J:156172
Jag1Ozz/Jag1+
involves: BALB/cOla * C3H
head bobbing J:83917
Jag1Ozz/Jag1Ozz
involves: BALB/cOla * C3H
head bobbing J:83917
Jag1Slalom/Jag1+
involves: BALB/c * C3H
abnormal cochlear sensory epithelium morphology J:67728
abnormal semicircular canal ampulla morphology J:67728
abnormal semicircular canal morphology J:67728
decreased cochlear outer hair cell number J:67728
head shaking J:67728
increased cochlear inner hair cell number J:67728
positive geotaxis J:67728
Jag1Slalom/Jag1Slalom
involves: BALB/c * C3H
abnormal neural tube morphology J:67728
abnormal vitelline vasculature morphology J:67728
embryonic lethality during organogenesis, complete penetrance J:67728
Jag1tm1.1Loo/Jag1tm1.1Loo
Tg(Alb1-cre)1Khk/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
no abnormal phenotype detected J:149131
Jag1tm1Frad/Jag1+
Tg(Six2-EGFP/cre)1Amc/0
involves: 129/Sv * C57BL/6 * CD-1
normal renal/urinary system phenotype J:198632
Jag1tm1Frad/Jag1tm1Frad
Tg(Cdh5-cre)7Mlia/0
B6.Cg-Jag1tm1Frad Tg(Cdh5-cre)7Mlia
abnormal aorta morphology J:189213
abnormal cardiac outflow tract development J:189213
abnormal coronary vessel morphology J:189213
abnormal heart morphology J:189213
abnormal heart valve morphology J:189213
abnormal pulmonary trunk morphology J:189213
calcified aortic valve J:189213
dilated heart J:189213
enlarged heart right atrium J:189213
heart right ventricle hypertrophy J:189213
increased heart right ventricle size J:189213
increased systemic arterial systolic blood pressure J:189213
normal liver/biliary system phenotype J:166890
normal mortality/aging J:166890
overriding aortic valve J:189213
pulmonary valve regurgitation J:189213
pulmonary valve stenosis J:189213
thick heart valve cusps J:189213
thick ventricular wall J:189213
ventricular septal defect J:189213
Jag1tm1Frad/Jag1tm1Frad
Tg(Mx1-cre)1Cgn/0
involves: 129 * C57BL/6 * CBA
normal hematopoietic system phenotype J:98129
Jag1tm1Frad/Jag1tm1Frad
Tg(Six2-EGFP/cre)1Amc/0
involves: 129/Sv * C57BL/6 * CD-1
decreased nephron number J:198632
Jag1tm1Frad/Jag1tm1Frad
Tg(Tagln-cre)1Her/0
B6.Cg-Jag1tm1Frad Tg(Tagln-cre)1Her
abnormal bile duct development J:166890
abnormal bile duct morphology J:166890
abnormal bile secretion J:166890
abnormal enzyme/coenzyme level J:166890
alopecia J:166890
cholestasis J:166890
decreased body weight J:166890
hepatic necrosis J:166890
increased circulating alanine transaminase level J:166890
increased circulating alkaline phosphatase level J:166890
increased circulating aspartate transaminase level J:166890
increased circulating bilirubin level J:166890
increased circulating cholesterol level J:166890
increased lactate dehydrogenase level J:166890
jaundice J:166890
lethargy J:166890
liver hemorrhage J:166890
neonatal lethality, incomplete penetrance J:166890
postnatal growth retardation J:166890
postnatal lethality, incomplete penetrance J:166890
Jag1tm1Grid/Jag1+
involves: 129S1/Sv * C57BL/6 * FVB
abnormal eye morphology J:54907
abnormal placement of pupils J:54907
corneal opacity J:54907
iris coloboma J:54907
irregularly shaped pupil J:54907
Jag1tm1Grid/Jag1tm1.1Loo
Tg(Alb1-cre)1Khk/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
abnormal bile secretion J:149131
bile duct proliferation J:149131
dilated bile duct J:149131
Jag1tm1Grid/Jag1tm1Grid
involves: 129S1/Sv * C57BL/6 * FVB
abnormal vascular development J:54907
abnormal vitelline vascular remodeling J:54907
embryonic lethality during organogenesis, complete penetrance J:54907
hemorrhage J:54907
pale yolk sac J:54907
Jag1tm1Grid/Jag1tm2Grid
Foxg1tm1(cre)Skm/Foxg1+
involves: 129P2/OlaHsd * 129S1/Sv
abnormal cochlea morphology J:115783
abnormal cochlear hair cell morphology J:115783
abnormal cochlear hair cell number J:115783
abnormal cochlear outer hair cell morphology J:115783
abnormal crista ampullaris morphology J:115783
abnormal lateral semicircular canal morphology J:115783
abnormal superior semicircular canal morphology J:115783
abnormal utricular macula morphology J:115783
abnormal vestibular saccule morphology J:115783
absent cochlear hair cells J:115783
absent semicircular canals J:115783
absent tunnel of Corti J:115783
decreased cochlear coiling J:115783
normal hearing/vestibular/ear phenotype J:115783
perinatal lethality, complete penetrance J:115783
small utricle J:115783
Jag1tm1Grid/Jag1tm2Grid
Tg(Tagln-cre)1Her/0
involves: 129S1/Sv * C57BL/6 * SJL
abnormal vascular smooth muscle morphology J:166769
cyanosis J:166769
patent ductus arteriosus J:166769
perinatal lethality, incomplete penetrance J:166769
postnatal lethality, complete penetrance J:166769
retroesophageal right subclavian artery J:166769
Jag1tm1Jlew/Jag1tm1Grid
Tg(Pdgfb-icre/ERT2)1Frut/0
involves: 129S1/Sv * C57BL/6 * CBA
abnormal angiogenesis J:157345
abnormal blood vessel morphology J:157345
abnormal retinal vasculature morphology J:157345
normal cardiovascular system phenotype J:157345
decreased angiogenesis J:157345
postnatal growth retardation J:157345
Jag1tm1Jlew/Jag1tm1Jlew
Foxg1tm1(cre)Skm/Foxg1+
involves: C57BL/6J
abnormal cochlear hair cell morphology J:107414
abnormal semicircular canal morphology J:107414
abnormal utricular macula morphology J:107414
absent cochlear outer hair cells J:107414
absent vestibular hair cells J:107414
increased cochlear inner hair cell number J:107414
Jag1tm1Jlew/Jag1tm1Jlew
Tg(Pdgfb-icre/ERT2)1Frut/0
involves: C57BL/6 * CBA
decreased angiogenesis J:157345
Jag1tm1Jlew/Jag1tm1Jlew
Tg(Tie1-cre)9Ref/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
abnormal vascular branching morphogenesis J:157345
fetal growth retardation J:157345
Jag1tm2.1Grid/Jag1tm2.1Grid
involves: 129S1/Sv * C57BL/6
abnormal vitelline vascular remodeling J:115783
distended pericardium J:115783
embryonic lethality during organogenesis, complete penetrance J:115783
intracranial hemorrhage J:115783
Jag1tm2Grid/Jag1tm2Grid
H2afvTg(Wnt1-cre)11Rth/0
involves: 129S1/Sv * C57BL/6 * CBA
abnormal blood vessel morphology J:181120
abnormal eating behavior J:181120
abnormal palate morphology J:181120
abnormal primary palate development J:181120
decreased body size J:181120
decreased palatal length J:181120
malocclusion J:181120
midface hypoplasia J:181120
premature death J:181120
short maxilla J:181120
Jag1tm2Grid/Jag1tm2Grid
Tg(Tek-cre)12Flv/0
involves: C3H * C57BL/6
abnormal vascular smooth muscle morphology J:166769
abnormal vitelline vascular remodeling J:166769
embryonic lethality during organogenesis, complete penetrance J:166769
hemorrhage J:166769
pericardial edema J:166769
Jag1Yo/Jag1+
C3HeB/FeJ-Jag1Yo
abnormal posterior semicircular canal morphology J:82809
abnormal superior semicircular canal morphology J:82809
decreased cochlear outer hair cell number J:82809
Jag1Yo/Jag1Yo
C3HeB/FeJ-Jag1Yo
embryonic lethality during organogenesis, complete penetrance J:82809

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last database update
07/10/2018
MGI 6.12
The Jackson Laboratory