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Hbb-bs Gene Detail
Summary
  • Symbol
    Hbb-bs
  • Name
    hemoglobin, beta adult s chain
  • Synonyms
    beta s
  • Feature Type
    protein coding gene
  • IDs
    MGI:5474852
    NCBI Gene: 100503605
  • Member of
    Hbb cluster
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:103475730-103477135 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, Syntenic
Strain
Comparison
more
  • SNPs within 2kb
    97 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_5474852
 protein coding gene Chr7:103475730-103477303 (-)
129S1/SvImJ MGP_129S1SvImJ_G0032683
 protein coding gene Chr7:107036977-107038541 (-)
A/J MGP_AJ_G0032656
 protein coding gene Chr7:104251438-104253002 (-)
AKR/J MGP_AKRJ_G0032589
 protein coding gene Chr7:106755957-106757210 (-)
BALB/cJ MGP_BALBcJ_G0032666
 protein coding gene Chr7:103978483-103980047 (-)
C3H/HeJ MGP_C3HHeJ_G0032377
 protein coding gene Chr7:107112587-107114151 (-)
C57BL/6NJ MGP_C57BL6NJ_G0033162
 protein coding gene Chr7:111026181-111026730 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0030158
 protein coding gene Chr7:106328803-106344316 (-)
CAST/EiJ MGP_CASTEiJ_G0031708
 protein coding gene Chr7:98645166-98666248 (-)
CBA/J MGP_CBAJ_G0032345
 protein coding gene Chr7:114948770-114951877 (-)
DBA/2J MGP_DBA2J_G0032499
 protein coding gene Chr7:102567071-102572337 (-)
FVB/NJ MGP_FVBNJ_G0032452
 protein coding gene Chr7:102292060-102293473 (-)
LP/J MGP_LPJ_G0032592
 protein coding gene Chr7:108350151-108351715 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0032488
 protein coding gene Chr7:116264254-116277570 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0033189
 protein coding gene Chr7:105957129-105960355 (-)
PWK/PhJ MGP_PWKPhJ_G0031422
 protein coding gene Chr7:95542935-95556878 (-)
SPRET/EiJ MGP_SPRETEiJ_G0031266
 protein coding gene Chr7:93226737-93237236 (-)
WSB/EiJ MGP_WSBEiJ_G0031822
 protein coding gene Chr7:106671576-106689325 (-)



Homology
more
  • Human Ortholog
    HBB, hemoglobin subunit beta
  • Vertebrate Orthologs
    6
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    HBB, hemoglobin subunit beta
  • Synonyms
    beta-globin, CD113t-C, ECYT6
  • Links
    NCBI Gene ID: 3043
    UniProt: P68871

  • Chr Location
    11p15.4; chr11:5225464-5229395 (-)  GRCh38
  • Human Ortholog
    HBD, hemoglobin subunit delta
  • Synonyms
    HBK
  • Links
    NCBI Gene ID: 3045
    UniProt: P02042

  • Chr Location
    11p15.4; chr11:5232678-5243657 (-)  GRCh38
Human Diseases
more
  • Diseases
    14 with human HBB associations

Human Disease Mouse Models
      
IDs
IDs
IDs
IDs
 View 17 models
IDs
IDs
IDs
IDs
IDs
IDs
IDs
IDs
IDs
 View 7 models
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    13 phenotype references
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    795
  • Tissues
    33
  • cDNA Data
    38
  • Literature Summary
    3
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 100503605 NCBI Gene Model | MGI Sequence Detail 1406 C57BL/6J ±  kb
transcript NM_001201391 RefSeq | MGI Sequence Detail 639 ZRU/MplStud  
polypeptide NP_001188320 RefSeq | MGI Sequence Detail 147 ZRU/MplStud  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
Molecular
Reagents
less
  • All nucleic 40
    cDNA 38
    Primer pair 2
References
more
  • Summaries
    All 26
    Developmental Gene Expression 3
    Phenotypes 13
  • Earliest
    J:32353 Weaver S, et al., The adult beta-globin genes of the single type mouse C57BL. Cell. 1981 May;24(2):403-11
  • Latest
    J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
03/24/2026
MGI 6.24 		The Jackson Laboratory