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Ifng
Gene Detail
 Symbol
Name
ID
Ifng
interferon gamma
MGI:107656
STS D10Mit24
Synonyms Ifg, IFN-gamma
Feature Type protein coding gene
Genetic Map
Chromosome 10
66.75 cM
Detailed Genetic Map ± 1 cM


Mapping data(47)
Sequence Map
Chr10:118441047-118445892 bp, + strand
From NCBI annotation of GRCm38

  4846 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:55526  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 dog

Protein SuperFamily: interferon gamma
Gene Tree: Ifng

Human
homologs
Human Homolog IFNG, interferon, gamma
NCBI Gene ID 3458
neXtProt AC  NX_P01579
Human Synonyms  IFG, IFI
Human Chr (Location)  12q14; chr12:68154770-68159741 (-)  GRCh38
Disease Associations  (5) Diseases Associated with Human IFNG
Mutations,
alleles, and
phenotypes
All mutations/alleles(8) : Targeted(8)
Incidental mutations (data from Mutagenetix , APF )
 
Mutants show immune system abnormalities including decreased inflammatory response in one line, and uncontrolled splenocyte proliferation and susceptibility to intracellular pathogens in another.
 
Human Diseases Modeled Using Mouse Ifng (2)    Alleles Annotated to Human Diseases(1)   
Interactions
Ifng interacts with 137 markers (Mir9-1, Mir9-2, Mir9-3, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (81 annotations)
Process adaptive immune response, antigen processing and presentation, ...
Component cell, external side of plasma membrane, ...
Function cytokine activity, interferon-gamma receptor binding, ...
External Resources: FuncBase
Expression
Literature Summary: (16 records)
Data Summary: Results (106)    Tissues (64)    Images (5)
Theiler Stages: 16, 18, 20, 21, 22, 23, 24, 25, 26, 27, 28
Assay TypeResults
RNA in situ 24
Northern blot 3
RT-PCR 79
cDNA source data(14)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(21) cDNA(15) Primer pair(5) Other(1)
Microarray probesets(3)
Other database
links
Ensembl Gene ModelENSMUSG00000055170 (Evidence)
Entrez Gene15978 (Evidence)
UniGene240327
DFCITC1582456
DoTSDT.101210515
NIA Mouse Gene IndexU012054
Consensus CDS ProjectCCDS24200.1
International Mouse Knockout Project StatusIfng
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 15978 NCBI Gene Model | MGI Sequence Detail 4846 C57BL/6J ±  kb
transcript NM_008337 RefSeq | MGI Sequence Detail 1207 C57BL/6 
polypeptide P01580 UniProt | EBI | MGI Sequence Detail 155 Not Applicable 

For the selected sequences
All sequences(24) RefSeq(2) UniProt(5)
Polymorphisms All PCR and RFLP(9) : PCR(1) RFLP(8) SNPs within 2kb(30 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR012351 Four-helical cytokine, core
InterPro IPR009079 Four-helical cytokine-like, core
InterPro IPR002069 Interferon gamma
Protein Ontology PR:000000017 interferon gamma
Graphical View of Protein Domain Structure
References (Earliest) J:19935 Gray PW, et al., Cloning and expression of murine immune interferon cDNA. Proc Natl Acad Sci U S A. 1983 Oct;80(19):5842-6
(Latest) J:212198 Wang Q, et al., Identification of interferon-gamma as a new molecular target of liver X receptor. Biochem J. 2014 Apr 15;459(2):345-54
All references(1466)
Disease annotation references (2)
Other
accession IDs
MGD-MRK-11214, MGD-MRK-36231

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/26/2014
MGI 5.19
The Jackson Laboratory