Automated description from the Alliance of Genome Resources (Release 9.0.0)
Enables cytokine activity. Involved in several processes, including glial cell activation; regulation of gene expression; and regulation of generation of precursor metabolites and energy. Acts upstream of or within several processes, including CD8-positive, alpha-beta T cell differentiation involved in immune response; positive regulation of gene expression; and response to bacterium. Located in external side of plasma membrane and extracellular region. Is expressed in several structures, including adipose tissue; alimentary system; genitourinary system; hemolymphoid system; and nervous system. Used to study several diseases, including aplastic anemia; hepatitis; malaria; medulloblastoma; and type 1 diabetes mellitus. Human ortholog(s) of this gene implicated in several diseases, including Graves' disease; ataxia telangiectasia; leukemia (multiple); liver disease (multiple); and tuberculosis (multiple). Orthologous to human IFNG (interferon gamma).
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