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Phenotype Images associated with this Pseudogene
Symbol
Name
ID 		Speer6-ps1
spermatogenesis associated glutamate (E)-rich protein 6, pseudogene 1
MGI:1920516


28 phenotype image(s) for Speer6-ps1 alleles
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Caption: Analysis of livers in mice with heterozygous and homozygous Fbxw7tm1.1Iken mutations (details)
Represented Alleles:
Fbxw7tm1Iken, F-box and WD-40 domain protein 7; targeted mutation 1, Tsuneo Ikenoue
Speer6-ps1Tg(Alb-cre)21Mgn, spermatogenesis associated glutamate (E)-rich protein 6, pseudogene 1; transgene insertion 21, Mark A Magnuson
Copyright: This image is from Ikenoue T, Sci Rep 2018 Jan 31;8(1):2021, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:258194
Caption: Liver histology in mice with heterozygous and homozygous Fbxw7tm1.1Iken mutations in combination with an oncogenic KrasG12D mutation (details)
Represented Alleles:
Fbxw7tm1Iken, F-box and WD-40 domain protein 7; targeted mutation 1, Tsuneo Ikenoue
Krastm4Tyj, Kirsten rat sarcoma viral oncogene homolog; targeted mutation 4, Tyler Jacks
Speer6-ps1Tg(Alb-cre)21Mgn, spermatogenesis associated glutamate (E)-rich protein 6, pseudogene 1; transgene insertion 21, Mark A Magnuson
Copyright: This image is from Ikenoue T, Sci Rep 2018 Jan 31;8(1):2021, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:258194
Caption: RNA oxidation in Glultm1.1Geno/Glultm1.1Geno Speer6-ps1Tg(Alb-cre)21Mgn/0 mouse brain (details)
Represented Alleles:
Glultm1.1Geno, glutamate-ammonia ligase; targeted mutation 1.1, Genoway
Speer6-ps1Tg(Alb-cre)21Mgn, spermatogenesis associated glutamate (E)-rich protein 6, pseudogene 1; transgene insertion 21, Mark A Magnuson
Copyright: This image is from Qvartskhava N, Proc Natl Acad Sci U S A 2015 Apr 28;112(17):5521-6. Copyright 2015 National Academy of Sciences, U.S.A. J:221031
Caption: The leucine metabolite 2-ketoisocaproate induces liver steatosis in Hmgcltm2Gam/Hmgcltm2Gam Speer6-ps1Tg(Alb-cre)21Mgn/0 mice (details)
Represented Alleles:
Hmgcltm2Gam, 3-hydroxy-3-methylglutaryl-Coenzyme A lyase; targeted mutation 2, Grant A Mitchell
Speer6-ps1Tg(Alb-cre)21Mgn, spermatogenesis associated glutamate (E)-rich protein 6, pseudogene 1; transgene insertion 21, Mark A Magnuson
Copyright: This image is from Gauthier N, PLoS One 2013;8(7):e60581, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:204294
Caption: Abnormalities of mitochondrial ultrastructure in Hmgcltm2Gam/Hmgcltm2Gam Speer6-ps1Tg(Alb-cre)21Mgn/0 hepatocytes (details)
Represented Alleles:
Hmgcltm2Gam, 3-hydroxy-3-methylglutaryl-Coenzyme A lyase; targeted mutation 2, Grant A Mitchell
Speer6-ps1Tg(Alb-cre)21Mgn, spermatogenesis associated glutamate (E)-rich protein 6, pseudogene 1; transgene insertion 21, Mark A Magnuson
Copyright: This image is from Gauthier N, PLoS One 2013;8(7):e60581, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:204294
Caption: Hepatomegaly and tumor-like protrusions in the liver of Ei24tm1Hzha/Ei24tm1Hzha Speer6-ps1Tg(Alb-cre)21Mgn/0 mice (details)
Represented Alleles:
Ei24tm1Hzha, etoposide induced 2.4 mRNA; targeted mutation 1, Hong Zhang
Speer6-ps1Tg(Alb-cre)21Mgn, spermatogenesis associated glutamate (E)-rich protein 6, pseudogene 1; transgene insertion 21, Mark A Magnuson
Copyright: This image is from Zhao YG, J Biol Chem 2012 Dec 7;287(50):42053-63 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:193420
Caption: Enlarged spleen and swollen liver mitochondria in Ei24tm1Hzha/Ei24tm1Hzha Speer6-ps1Tg(Alb-cre)21Mgn/0 mice (details)
Represented Alleles:
Ei24tm1Hzha, etoposide induced 2.4 mRNA; targeted mutation 1, Hong Zhang
Speer6-ps1Tg(Alb-cre)21Mgn, spermatogenesis associated glutamate (E)-rich protein 6, pseudogene 1; transgene insertion 21, Mark A Magnuson
Copyright: This image is from Zhao YG, J Biol Chem 2012 Dec 7;287(50):42053-63 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:193420
Caption: Kinked spermatozoa in Selenoptm3.1Rfb/Selenoptm3.1Rfb Speer6-ps1Tg(Alb-cre)21Mgn/0 mice fed a selenium-deficient diet (details)
Represented Alleles:
Selenoptm3.1Rfb, selenoprotein P; targeted mutation 3.1, Raymond F Burk
Speer6-ps1Tg(Alb-cre)21Mgn, spermatogenesis associated glutamate (E)-rich protein 6, pseudogene 1; transgene insertion 21, Mark A Magnuson
Copyright: This image is from Hill KE, J Biol Chem 2012 Nov 23;287(48):40414-24 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:192636
Caption: Curling and splaying of hind limbs in Selenoptm3.1Rfb/Selenoptm3.1Rfb Speer6-ps1Tg(Alb-cre)21Mgn/0 mice fed a selenium-deficient diet (details)
Represented Alleles:
Selenoptm3.1Rfb, selenoprotein P; targeted mutation 3.1, Raymond F Burk
Speer6-ps1Tg(Alb-cre)21Mgn, spermatogenesis associated glutamate (E)-rich protein 6, pseudogene 1; transgene insertion 21, Mark A Magnuson
Copyright: This image is from Hill KE, J Biol Chem 2012 Nov 23;287(48):40414-24 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:192636
Caption: Abnormal liver structure in Mir122tm1.2Kgh/Mir122tm1.2Kgh Speer6-ps1Tg(Alb-cre)21Mgn/0 mice (details)
Represented Alleles:
Mir122tm1.2Kgh, microRNA 122; targeted mutation 1.2, Kalpana Ghoshal
Speer6-ps1Tg(Alb-cre)21Mgn, spermatogenesis associated glutamate (E)-rich protein 6, pseudogene 1; transgene insertion 21, Mark A Magnuson
Copyright: This image is from Hsu SH, J Clin Invest 2012 Aug 1;122(8):2871-83 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:190067
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/30/2024
MGI 6.23 		The Jackson Laboratory