Glultm1.1Geno
Targeted Allele Detail
|
Symbol: |
Glultm1.1Geno |
Name: |
glutamate-ammonia ligase; targeted mutation 1.1, Genoway |
MGI ID: |
MGI:5750936 |
Synonyms: |
Glulfl |
Gene: |
Glul Location: Chr1:153775692-153785469 bp, + strand Genetic Position: Chr1, 65.43 cM, cytoband G2
|
Alliance: |
Glultm1.1Geno page
|
|
RNA oxidation in Glultm1.1Geno/Glultm1.1Geno Speer6-ps1Tg(Alb-cre)21Mgn/0 mouse brain
Show the 1 phenotype image(s) involving this allele.
|
|
|
Germline Transmission: |
Earliest citation of germline transmission:
J:221031
|
Parent Cell Line: |
Not Specified (ES Cell)
|
Strain of Origin: |
Not Specified
|
|
Allele Type: |
|
Targeted (Conditional ready) |
Mutation: |
|
Insertion
|
|
|
Mutation details: A loxP site was inserted downstream of exon 1a and an FRT flanked selection cassette and loxP site were inserted downstream of exon 2 via homologous recombination. Flp mediated recombination removed the neo cassette.
(J:221031)
|
|
Generation of the Glultm1.1Geno allele |
|
|
View phenotypes and curated references for all genotypes (concatenated display).
|
|
Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
|
Carrying any Glul Mutation: |
33 strains or lines available
|
|
Original: |
J:221031 Qvartskhava N, et al., Hyperammonemia in gene-targeted mice lacking functional hepatic glutamine synthetase. Proc Natl Acad Sci U S A. 2015 Apr 28;112(17):5521-6 |
All: |
4 reference(s) |
|