About   Help   FAQ
Phenotype Images associated with this Transgene
Nomenclature
Symbol: Tg(Nes-cre)1Kln
Name: transgene insertion 1, Rudiger Klein
MGI ID: MGI:2176173
Synonyms: n-Cre+, Nestin:Cre, nestin-Cre, NesCre, Nes11Cre, Tg(Nes-cre), nestin/Cre
Images for
Allele
Click images for details
Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Ndfip1tm1Sest/Ndfip1tm1Sest Tg(Nes-cre)1Kln/0 mice show increased infract size after hypoxia-ischemiaNdfip1tm1Sest/Ndfip1tm1Sest
Tg(Nes-cre)1Kln/0		involves: C57BL/6 * SJL
Ndfip1tm1Sest/Ndfip1tm1Sest Tg(Nes-cre)1Kln/0 mice show increased neuron death after hypoxia-ischemiaNdfip1tm1Sest/Ndfip1tm1Sest
Tg(Nes-cre)1Kln/0		involves: C57BL/6 * SJL
Cerebellar ataxia in Smad2tm1.1Nomu/Smad2tm1.1Nomu Tg(Nes-cre)1Kln/0 miceSmad2tm1.1Nomu/Smad2tm1.1Nomu
Tg(Nes-cre)1Kln/0		involves: C57BL/6 * SJL
Cerebellar development abnormalities in Smad2tm1.1Nomu/Smad2tm1.1Nomu Tg(Nes-cre)1Kln/0 miceSmad2tm1.1Nomu/Smad2tm1.1Nomu
Tg(Nes-cre)1Kln/0		involves: C57BL/6 * SJL
Increased apoptotic cell death in Smad2tm1.1Nomu/Smad2tm1.1Nomu Tg(Nes-cre)1Kln/0 cerebellaSmad2tm1.1Nomu/Smad2tm1.1Nomu
Tg(Nes-cre)1Kln/0		involves: C57BL/6 * SJL
Impaired cerebellar granule cell maturation and migration in Smad2tm1.1Nomu/Smad2tm1.1Nomu Tg(Nes-cre)1Kln/0 miceSmad2tm1.1Nomu/Smad2tm1.1Nomu
Tg(Nes-cre)1Kln/0		involves: C57BL/6 * SJL
Purkinje cell defects in Smad2tm1.1Nomu/Smad2tm1.1Nomu Tg(Nes-cre)1Kln/0 miceSmad2tm1.1Nomu/Smad2tm1.1Nomu
Tg(Nes-cre)1Kln/0		involves: C57BL/6 * SJL
Reduced synaptic density in Smad2tm1.1Nomu/Smad2tm1.1Nomu Tg(Nes-cre)1Kln/0 miceSmad2tm1.1Nomu/Smad2tm1.1Nomu
Tg(Nes-cre)1Kln/0		involves: C57BL/6 * SJL
Gbatm1Karl/Gbatm1Karl Tg(Nes-cre)1Kln/? mice exhibit a more profound activation and proliferation of microglial cells than Gbatm2Karl/Gbatm2Karl Tg(KRT14-cre)8Brn/? miceGbatm2Karl/Gbatm2Karl
Tg(KRT14-cre)8Brn/?		involves: 129S1/Sv * 129X1/SvJ * FVB/N
Gbatm1Karl/Gbatm1Karl
Tg(Nes-cre)1Kln/?		involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
Neural-specific STAT3 deletion results in severe obesity in Stat3tm1Flv/Stat3tm1Flv Tg(Nes-cre)1Kln/0 mice similar to that seen in Leprdb/Leprdb miceLeprdb/Leprdbinvolves: C57BLKS/J
Stat3tm1Flv/Stat3tm1Flv
Tg(Nes-cre)1Kln/0		involves: C57BL/6 * SJL
Hyperphagia and fatty livers in Stat3tm1Flv/Stat3tm1Flv Tg(Nes-cre)1Kln/0 miceStat3tm1Flv/Stat3tm1Flv
Tg(Nes-cre)1Kln/0		involves: C57BL/6 * SJL
Stat3tm1Flv/Stat3tm1Flv Tg(Nes-cre)1Kln/0 mice are infertile, hypogonadal and shortStat3tm1Flv/Stat3tm1Flv
Tg(Nes-cre)1Kln/0		involves: C57BL/6 * SJL
Adipose tissue is altered in Stat3tm1Flv/Stat3tm1Flv Tg(Nes-cre)1Kln/0 miceStat3tm1Flv/Stat3tm1Flv
Tg(Nes-cre)1Kln/0		involves: C57BL/6 * SJL
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support. 		last database update
05/08/2013
MGI 5.13 		The Jackson Laboratory