Excel File Text File All mouse models of high grade glioma with phenotypic similarity to the human disease
        Disease Term Allelic Composition Genetic Background Reference Phenotypes
      glioblastoma Trp53tm1Elee/Trp53tm1Tyj
Tg(GFAP-cre)25Mes/0
involves: 129S2/SvPas * 129S4/SvJae * FVB/N J:149662 View
glioblastoma Nf1tm1Fcr/Nf1tm1Fcr
Trp53tm1Elee/Trp53tm1Elee
Tg(GFAP-cre)25Mes/0
involves: 129S/SvEv * 129S4/SvJae * FVB/N J:149662 View
high grade glioma Tg(GFAP-Hras1)2Agu/Tg(GFAP-Hras1)2Agu involves: 129S1/Sv * 129X1/SvJ * ICR J:69129 View
malignant astrocytoma Tg(GFAP-Hras1)2Agu/Tg(GFAP-Hras1)2Agu involves: 129S1/Sv * 129X1/SvJ * ICR J:69129 View
      high grade glioma Cdkn2atm1Rdp/Cdkn2atm1Rdp
Col1a1tm1(CAG-EGFR)Char/Col1a1tm1(CAG-EGFR)Char
Ptentm1Hwu/Ptentm1Hwu
involves: 129/Sv * 129S4/SvJae * C57BL/6 * SJL J:146494 View
high grade glioma Cdkn2atm1Rdp/Cdkn2atm1Rdp
Col1a1tm1(CAG-EGFR)Char/Col1a1tm2(CAG-EGFR*)Char
Ptentm1Hwu/Ptentm1Hwu
involves: 129/Sv * 129S4/SvJae * C57BL/6 * SJL J:146494 View
high grade glioma Cdkn2atm1Rdp/Cdkn2atm1Rdp
Col1a1tm2(CAG-EGFR*)Char/Col1a1tm2(CAG-EGFR*)Char
Ptentm1Hwu/Ptentm1Hwu
involves: 129/Sv * 129S4/SvJae * C57BL/6 * SJL J:146494 View
high grade glioma Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sortm1Sor
Ptentm1Mro/Ptentm1Mro
Slc1a3tm1(cre/ERT2)Mgoe/Slc1a3+
Trp53tm1Brn/Trp53tm1Brn
involves: 129P2/OlaHsd * 129S2/SvPas * 129S4/SvJaeSor J:229481 View
high grade glioma Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sortm1Sor
Ptentm1Mro/Ptentm1Mro
Trp53tm1Brn/Trp53tm1Brn
involves: 129P2/OlaHsd * 129S4/SvJaeSor J:229481 View
high grade glioma Tg(S100b-v-erbB)4496Waw/0
Trp53tm1Brd/Trp53tm1Brd
involves: 129S7/SvEvBrd * C57BL/6J * DBA/2J J:137800 View
Transgenes and
Other Mutations
     malignant astrocytoma Ptentm2.1Ppp/Ptentm2.1Ppp
Tg(GFAP-TAg121)1Tvd/0
involves: 129S1/Sv * C57BL/6 * C57BL/6J * DBA/2 * FVB/N J:99385 View
malignant astrocytoma Tg(GFAP-SRC)1Aag/0 involves: C3H * C57BL/6 J:40335 View
malignant astrocytoma Tg(GFAP-SRC)2Aag/0 involves: C3H * C57BL/6 J:40335 View
malignant astrocytoma Tg(GFAP-TAg121)1Tvd/0 involves: C57BL/6 * DBA/2 * FVB/N J:77132 View
oligodendroglioma Cdkn2atm1Rdp/Cdkn2atm1Rdp
Tg(S100b-v-erbB)4496Waw/0
involves: 129/Sv * C57BL/6J * DBA/2J * FVB/N * SJL J:82649 View
oligodendroglioma Cdkn2atm1Rdp/Cdkn2a+
Tg(S100b-v-erbB)4496Waw/0
involves: 129/Sv * C57BL/6J * DBA/2J * FVB/N * SJL J:82649 View
oligodendroglioma Tg(S100b-v-erbB)4496Waw/0
Trp53tm1Brd/Trp53+
involves: 129S7/SvEvBrd * C57BL/6J * DBA/2J * FVB/N J:82649 View
oligodendroglioma Tg(S100b-v-erbB)4496Waw/0 involves: C57BL/6J * DBA/2J * FVB/N J:82649 View
Additional
Complex
Models
     glioblastoma proneural subtype Gt(ROSA)26Sortm2Thl/Gt(ROSA)26Sor+
Ptentm1Hwu/Ptentm1Hwu
Trp53tm1Thl/Trp53tm1Thl
Tyrc-Brd/Tyrc-Brd
involves: 129/Sv * 129S4/SvJae * C57BL/6 J:172585 View
glioblastoma proneural subtype Gt(ROSA)26Sortm2Thl/Gt(ROSA)26Sor+
Ptentm1Hwu/Ptentm1Hwu
Tyrc-Brd/Tyrc-Brd
involves: 129/Sv * 129S4/SvJae * C57BL/6 J:172585 View
malignant astrocytoma Nf1tm1Tyj/Nf1+
Trp53tm1Tyj/Trp53+
(C3H/HeJ x B6.129S2-Trp53tm1Tyj Nf1tm1Tyj/+ +)F1 J:64364 View
malignant astrocytoma Nf1tm1Tyj/Nf1+
Trp53tm1Tyj/Trp53+
(CAST/EiJ x B6.129S2-Trp53tm1Tyj Nf1tm1Tyj/+ +)F1 J:64364 View
malignant astrocytoma Nf1tm1Tyj/Nf1+
Trp53tm1Tyj/Trp53+
(CBA/J x B6.129S2-Trp53tm1Tyj Nf1tm1Tyj/+ +)F1 J:64364 View
malignant astrocytoma Nf1tm1Tyj/Nf1+
Trp53tm1Tyj/Trp53+
(SJL/J x B6.129S2-Trp53tm1Tyj Nf1tm1Tyj/+ +)F1 J:64364 View
malignant astrocytoma Nf1tm1Tyj/Nf1+
Trp53tm1Tyj/Trp53+
B6.129S2-Trp53tm1Tyj Nf1tm1Tyj/+ + J:64364 View
malignant astrocytoma Nf1tm1Par/Nf1+
Ptentm1Hwu/Pten+
Trp53tm1Tyj/Trp53+
Tg(GFAP-cre)25Mes/0
involves: 129S1/Sv * 129S2/SvPas * 129S4/SvJae * 129X1/SvJ * FVB/N J:134611 View
malignant astrocytoma Nf1tm1Par/Nf1+
Trp53tm1Tyj/Trp53+
Tg(GFAP-cre)25Mes/0
involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * FVB/N J:134611 View
malignant astrocytoma Nf1tm1Par/Nf1+
Trp53tm1Elee/Trp53+
Tg(GFAP-cre)25Mes/0
involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * FVB/N J:134611 View
oligodendroglioma Cdkn2atm1Rdp/Cdkn2atm1Rdp
Tg(NES-TVA)J12Ech/0
involves: 129/Sv * C57BL/6 * FVB/N * SJL J:153220 View