Phenotypes Associated with This Genotype

Genotype
MGI:3822319

• Allelic Composition: Tg(S100b-v-erbB)4496Waw/0
• Genetic Background: involves: C57BL/6J * DBA/2J * FVB/N

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

premature death ( J:82649 )

• within 6 months, 50% of mice die or are euthanized due to glioma development

• after 1 year, 24 of 38 mice (63%) die due to glioma development with the exception of 4 mice that die of unknown causes

neoplasm

increased oligodendroglioma incidence ( J:82649 )

• mice develop oligodendroglioma

• within 6 months, 50% of mice die or are euthanized due to glioma development

• after 1 year, 24 of 38 mice die due to glioma development with the exception of 4 mice that die of unknown causes

nervous system

increased oligodendroglioma incidence ( J:82649 )

• mice develop oligodendroglioma

• within 6 months, 50% of mice die or are euthanized due to glioma development

• after 1 year, 24 of 38 mice die due to glioma development with the exception of 4 mice that die of unknown causes

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
oligodendroglioma		DOID:3181		J:82649