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Phenotypes Associated with This Genotype
Genotype
MGI:3822321
Allelic
Composition		 Cdkn2atm1Rdp/Cdkn2a+
Tg(S100b-v-erbB)4496Waw/0
Genetic
Background		 involves: 129/Sv * C57BL/6J * DBA/2J * FVB/N * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cdkn2atm1Rdp mutation (6 available); any Cdkn2a mutation (62 available)
Tg(S100b-v-erbB)4496Waw mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
neoplasm
increased glioma incidence ( J:82649 )
• mice develop gliomas as in Cdkn2atm1Rdp/Cdkn2atm1Rdp Tg(S100b-v-erbB)4496Waw mice with loss of function of the wild-type Cdkn2a allele

nervous system
increased glioma incidence ( J:82649 )
• mice develop gliomas as in Cdkn2atm1Rdp/Cdkn2atm1Rdp Tg(S100b-v-erbB)4496Waw mice with loss of function of the wild-type Cdkn2a allele

Mouse Models of Human Disease
 DO ID OMIM ID(s) Ref(s)
oligodendroglioma DOID:3181 J:82649

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory