Excel File Text File All mouse models of organ system benign neoplasm with phenotypic similarity to the human disease
        Disease Term Allelic Composition Genetic Background Reference Phenotypes
      arteriovenous malformations of the brain Engtm2.1Hma/Engtm2.1Hma involves: 129P2/OlaHsd J:196810 View
infantile myofibromatosis Pdgfrbb2b2903Clo/Pdgfrbb2b2903Clo C57BL/6J-Pdgfrbb2b2903Clo J:175213 View
pheochromocytoma Rettm2.1Cos/Rettm2.1Cos involves: 129S1/Sv * C57BL/6J * FVB/N J:60659 View
von Hippel-Lindau disease Vhltm1Lss/Vhltm1Lss
Tg(Gcg-cre)1Slib/0
either: (involves: 129X1/SvJ * A/J) or (involves: 129X1/SvJ * C57BL/6) J:148174 View
von Hippel-Lindau disease Vhltm1Lss/Vhltm1Lss
Tg(Ins2-cre)25Mgn/0
either: (involves: 129X1/SvJ * C57BL/6 * DBA) or (involves: 129X1/SvJ * A/J * C57BL/6 * DBA) J:148174 View
von Hippel-Lindau disease Hif1atm3Rsjo/Hif1atm3Rsjo
Hprttm1(Pck1-cre)Vhh/Y
Vhltm1Jae/Vhltm1Jae
involves: 129 * BALB/c * C57BL/6 J:97652, J:106705 View
von Hippel-Lindau disease Hif1atm3Rsjo/Hif1atm3Rsjo
Vhltm1Jae/Vhltm1Jae
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
involves: 129 * BALB/c * C57BL/6 * DBA J:97652 View
von Hippel-Lindau disease Hprttm1(Pck1-cre)Vhh/Y
Vhltm1Jae/Vhltm1Jae
involves: 129P2/OlaHsd * 129S4/SvJae * BALB/c * C57BL/6 J:97652, J:106705 View
von Hippel-Lindau disease Vhltm1.1Jae/Vhl+ involves: 129S4/SvJae * BALB/c J:67505 View
von Hippel-Lindau disease Vhltm1Jae/Vhltm1Jae
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
involves: 129S4/SvJae * BALB/c * C57BL/6 * DBA J:67505, J:97652 View
von Hippel-Lindau disease Ptentm1Hwu/Ptentm1Hwu
Vhltm1Jae/Vhltm1Jae
Tg(Cdh16-cre)91Igr/0
involves: 129S4/SvJae * BALB/c * C57BL/6J * ICR J:137073 View
von Hippel-Lindau disease Vhltm1Wml/Vhltm1Wml involves: 129S4/SvJae * C57BL/6 J:42846, J:88492 View
von Hippel-Lindau disease Vhltm1.1Wkr/Vhl+ involves: 129S4/SvJae * C57BL/6 J:157369 View
von Hippel-Lindau disease Ptentm1Hwu/Ptentm1Hwu
Vhltm1Jae/Vhltm1Jae
Tg(Cdh16-cre)91Igr/0
involves: 129S4/SvJae * ICR J:137442 View
von Hippel-Lindau disease Vhltm1Lss/Vhltm1.1Lss
Tg(ACTB-cre)1Tes/0
involves: 129X1/SvJ * C3H * C57BL/6 J:85513 View
von Hippel-Lindau disease Vhltm1Lss/Vhltm1.1Lss involves: 129X1/SvJ * C57BL/6 J:85513 View
von Hippel-Lindau disease Vhltm1Lss/Vhltm1Lss
Tg(Pdx1-cre)89.1Dam/0
involves: 129X1/SvJ * C57BL/6 * CBA J:148174 View
von Hippel-Lindau disease Vhltm1.1Lss/Vhl+ involves: A/J J:85513 View
von Hippel-Lindau disease Vhltm1.1Lss/Vhl+ involves: BALB/c J:85513 View
      arteriovenous malformations of the brain Acvrl1tm2.1Spo/Acvrl1tm2.1Spo involves: 129 J:196810 View
arteriovenous malformations of the brain Tg(Tek-tTA)1Rwng/0
Tg(tetO-Notch4*)1Rwng/0
involves: FVB/N J:139943 View
dermoid cyst of ovary Foxo3mommeR1/Foxo3mommeR1
Tg(HBA1-GFP)1Ew/Tg(HBA1-GFP)1Ew
FVB/NJ-Foxo3mommeR1 Tg(HBA1-Gfp)1Ew J:170710 View
epidermal appendage tumor Tg(Tff3-Tmem207)1Tamo/0 C57BL/6-Tg(Tff3-Tmem207)1Tamo J:217436 View
growth hormone secreting pituitary adenoma Men1tm1Zqw/Men1+ involves: 129/Sv * 129P2/OlaHsd J:85302 View
hepatocellular adenoma Ptpn11tm1Gsf/Ptpn11tm1Gsf
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA J:172422 View
prolactinoma Men1tm1Zqw/Men1+ involves: 129/Sv * 129P2/OlaHsd J:85302 View
uterine fibroid Tsc2tm1.1Mjg/Tsc2tm1.1Mjg
Pgrtm2(cre)Lyd/Pgr+
involves: 129S1/Sv * 129X1/SvJ J:221228 View
      pheochromocytoma Ptentm1Mro/Ptentm1Mro
Sdhbtm1.1Ics/Sdhb+
Tg(KLK3-cre)D4Trp/0
involves: 129S2/SvPas * FVB J:236514 View
Transgenes and
Other Mutations
     ACTH-secreting pituitary adenoma Tg(PyLT)1Vb/0 Not Specified J:55528 View
choroid plexus papilloma Smarcb1tm1Sho/Smarcb1+
Tg(LPV-TAg121)2Tvd/0
involves: 129S6/SvEvTac * C57BL/6J * DBA/2J J:120820 View
choroid plexus papilloma Tg(LPV-TAg121)2Tvd/0 involves: 129S6/SvEvTac * C57BL/6J * DBA/2J J:120820 View
dermoid cyst of ovary Tg(Amh-SMAD2*)#Jebu/0 FVB/N-Tg(Amh-SMAD2*)#Jebu J:200783 View
insulinoma Tg(RIP1-Tag)2Dh/0 involves: C57BL/6J * DBA/2J J:205389 View
lung benign neoplasm Tg(Scgb1a1-rtTA)1Jaw/0
Tg(tetO/CMV-KRAS*G12C)9.1Msmi/0
involves: FVB/N J:102839 View
lung benign neoplasm Tg(SFTPC-rtTA)5Jaw/0
Tg(tetO/CMV-KRAS*G12C)9.1Msmi/0
involves: FVB/N J:102839 View
prolactinoma Tg(Prl-EGFR)#Sme/0 Not Specified J:219654 View
von Hippel-Lindau disease Tg(Ggt1-Hif1a*)43Log/0 involves: C57BL/6 J:177381 View
Additional
Complex
Models
     pancreatic mucinous cystadenoma Apctm2Rak/Apc+
Trp53tm1Brn/Trp53tm1Brn
Tg(Pdx1-cre)6Tuv/0
involves: 129/Sv * 129P2/OlaHsd * C57BL/6J * FVB/N * SJL J:234310 View
seborrheic keratosis Psen1tm1Bdes/Psen1+
Psen2tm1Bdes/Psen2tm1Bdes
involves: 129P2/OlaHsd J:91235 View


       
No similarity to the expected human disease phenotype was found.
        Disease Term Allelic Composition Genetic Background Reference Phenotypes
NOT Models      paraganglioma Sdhdtm1Jpb/Sdhd+ either: 129P2/OlaHsd-Sdhdtm1Jpb or (involves: 129P2/OlaHsd * C57BL/6J) J:155380 View
paraganglioma Sdhctm1c(EUCOMM)Wtsi/Sdhctm1c(EUCOMM)Wtsi
Gt(ROSA)26Sortm1.1(rtTA,tetO-cre)Bkmn/Gt(ROSA)26Sor+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6N J:284745 View
paraganglioma Sdhdtm1Jlob/Sdhdtm1Jlob involves: 129X1/SvJ J:95252 View
paraganglioma Sdhdtm1Jlob/Sdhd+ involves: 129X1/SvJ J:95252 View
pheochromocytoma Rettm1Cos/Rettm2.1Cos involves: 129S/SvEv * 129S1/Sv * C57BL/6J * FVB/N * MF1 J:60659 View