Eng^tm2.1Hma
Targeted Allele Detail

Summary

• Symbol: Eng^tm2.1Hma
• Name: endoglin; targeted mutation 2.1, Helen M Arthur
• MGI ID: MGI:3712802
• Synonyms: Eng^2f
• Gene: Eng Location: Chr2:32536607-32572681 bp, + strand Genetic Position: Chr2, 22.09 cM
• Alliance: Eng^tm2.1Hma page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:121898
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: Exons 5 and 6 remained flanked by loxp sites following the removal of a floxed neo by cre mediated recombination. (J:121898)

Disease models

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Eng Mutation: 41 strains or lines available

References

• Original: J:121898 Allinson KR, et al., Generation of a floxed allele of the mouse endoglin gene. Genesis. 2007 Jun;45(6):391-5
• All: 18 reference(s)