Phenotypes for Ret MGI:3583336 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Ret^tm1Cos/Ret^tm2.1Cos
Genetic Background	involves: 129S/SvEv * 129S1/Sv * C57BL/6J * FVB/N * MF1

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ret^tm1Cos mutation (2 available); any Ret mutation (52 available)
Ret^tm2.1Cos mutation (1 available); any Ret mutation (52 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

endocrine/exocrine glands

endocrine/exocrine gland phenotype ( J:60659 )

N	• do not exhibit ganglioneuromas, nodular chromaffin cell hyperplasia or pheochromocytomas

reproductive system

reproductive system phenotype ( J:60659 )

N	• males are fertile

neoplasm

neoplasm ( J:60659 )

N	• do not exhibit ganglioneuromas or pheochromocytomas

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
NOT	multiple endocrine neoplasia type 2B	DOID:10016	OMIM:162300	J:60659
NOT	pheochromocytoma	DOID:0050771	OMIM:171300	J:60659

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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