inflammatory bowel disease Disease Ontology Browser

Disease Ontology Browser

inflammatory bowel disease (DOID:0050589)
Alliance: disease page
Alt IDs: EFO:0003767, KEGG:05321, MESH:D015212, NCI:C3138, OMIM:PS266600, UMLS_CUI:C0021390
Definition: An intestinal disease characterized by inflammation located in all parts of digestive tract.

Term Browser
Genes (76)
Models (37)

Disease References using Mouse Models (49)

Mouse Models

Human Disease Modeled: inflammatory bowel disease
Associated Mouse Gene: Il10

Allelic Composition	Genetic Background	Reference	Phenotypes
Il10tm1Cgn/Il10tm1Cgn Tg(MUC1)79.24Gend/0	B6.Cg-Il10^tm1Cgn Tg(MUC1)79.24Gend	J:149347	View
Il10tm1Cgn/Il10tm1Cgn	B6.129P2-Il10^tm1Cgn/J	J:124308, J:149347	View
Il10tm1Cgn/Il10tm1Cgn	involves: 129P2/OlaHsd * C57BL/6	J:15222, J:35020	View

Mouse Models

Human Disease Modeled: inflammatory bowel disease
Associated Mouse Gene: Cd40lg

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(Igh-V-CD40lg)#Tsub/0	involves: C57BL/6	J:89855	View

Mouse Models

Human Disease Modeled: inflammatory bowel disease
Associated Mouse Gene: Il2

Allelic Composition	Genetic Background	Reference	Phenotypes
Il2tm1Hor/Il2tm1Hor	involves: 129P2/OlaHsd * C57BL/6	J:15223	View
B2mtm1Unc/B2mtm1Unc Il2tm1Hor/Il2tm1Hor	involves: 129 * C57BL/6	J:51450	View

Mouse Models

Human Disease Modeled: inflammatory bowel disease
Associated Mouse Gene: Il2ra

Allelic Composition	Genetic Background	Reference	Phenotypes
Il2ratm1Dw/Il2ratm1Dw	involves: 129S4/SvJae * C57BL/6	J:64279	View

Mouse Models

Human Disease Modeled: inflammatory bowel disease
Associated Mouse Gene: Muc2

Allelic Composition	Genetic Background	Reference	Phenotypes
Muc2tm1Avel/Muc2tm1Avel	involves: 129P2/OlaHsd * C57BL/6	J:216831	View
Muc2wnn/Muc2wnn	C57BL/6-Muc2^wnn	J:194148	View
Muc2eey/Muc2eey	C57BL/6-Muc2^eey	J:194148	View

Mouse Models

Human Disease Modeled: inflammatory bowel disease
Associated Mouse Gene: Nfil3

Allelic Composition	Genetic Background	Reference	Phenotypes
Nfil3tm1Pbro/Nfil3tm1Pbro	B6.129S6-Nfil3^tm1Pbro	J:209365	View

Mouse Models

Human Disease Modeled: inflammatory bowel disease
Associated Mouse Gene: Runx3

Allelic Composition	Genetic Background	Reference	Phenotypes
Runx3tm1Yg/Runx3tm1Yg	either: (involves: 129S1/Sv * 129X1/SvJ * ICR) or (involves: 129S1/Sv * 129X1/SvJ * MF1)	J:93240	View

Mouse Models

Human Disease Modeled: inflammatory bowel disease
Associated Mouse Gene: Stat3

Allelic Composition	Genetic Background	Reference	Phenotypes
Stat3tm1Flv/Stat3tm1Flv Tg(Tek-cre)1Xyfu/0	involves: C57BL/6	J:86655	View
Stat3tm1Dlv/Stat3tm1Dlv Tg(Csf1r-icre)1Jwp/0	involves: 129P2/OlaHsd * C57BL/6 * FVB	J:156593	View
Stat3tm1Flv/Stat3tm1Flv Tg(Tek-cre)12Flv/0	involves: 129 * C3H * C57BL/6	J:81973	View

Mouse Models

Human Disease Modeled: inflammatory bowel disease
Associated Mouse Gene: Tnf

Allelic Composition	Genetic Background	Reference	Phenotypes
Tnftm2Gkl/Tnftm2Gkl	involves: 129S/SvEv * C57BL/6	J:54056	View
Tnftm2Gkl/Tnf+	involves: 129S/SvEv * C57BL/6	J:54056, J:136667, J:204922	View
Tnftm1Gkl/Tnftm2Gkl	involves: 129S/SvEv * C57BL/6	J:54056	View
Tnftm2.1Gkl/Tnftm2.1Gkl Tg(Fabp1-cre)1Jig/0	involves: 129S/SvEv * FVB/N	J:204557	View

Mouse Models

Human Disease Modeled: inflammatory bowel disease
Associated Mouse Gene: Xbp1

Allelic Composition	Genetic Background	Reference	Phenotypes
Xbp1tm2Glm/Xbp1tm2Glm Tg(Vil1-cre)997Gum/0	involves: 129S6/SvEvTac * C57BL/6J * FVB/N * SJL	J:188627	View

Mouse Models

Human Disease Modeled: inflammatory bowel disease

Allelic Composition	Genetic Background	Reference	Phenotypes
B2mtm1Unc/B2mtm1Unc Il2tm1Hor/Il2tm1Hor	involves: 129 * C57BL/6	J:51450	View

Mouse Models

Human Disease Modeled: inflammatory bowel disease
Associated Mouse Complex/Cluster/Region: Tcra

Allelic Composition	Genetic Background	Reference	Phenotypes
Tcratm1Mom/Tcratm1Mom	B6.129S2-Tcra^tm1Mom	J:135597	View
Tcratm1Mom/Tcratm1Mom	involves: 129S2/SvPas * C57BL/6	J:15221	View

Mouse Models

Human Disease Modeled: inflammatory bowel disease
Associated Mouse Transgene: Tg(Igh-V-CD40lg)#Tsub

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(Igh-V-CD40lg)#Tsub/0	involves: C57BL/6	J:89855	View

Mouse Models

Human Disease Modeled: inflammatory bowel disease

Allelic Composition	Genetic Background	Reference	Phenotypes
Gpx1tm1Ysh/Gpx1tm1Ysh Gpx2tm2Coh/Gpx2tm2Coh	involves: 129S1/Sv * 129X1/SvJ * C57BL/6J	J:71506	View

Mouse Models

Human Disease Modeled: inflammatory bowel disease

Allelic Composition	Genetic Background	Reference	Phenotypes
Gpx1tm1Ysh/Gpx1+ Gpx2tm2Coh/Gpx2tm2Coh	involves: 129S1/Sv * 129X1/SvJ * C57BL/6J	J:71506	View

Mouse Models

Human Disease Modeled: inflammatory bowel disease

Allelic Composition	Genetic Background	Reference	Phenotypes
Il10rbtm1Agt/Il10rbtm1Agt Tg(Cd4-TGFBR2)16Flv/?	involves: 129S2/SvPas * C3H * C57BL/6	J:134156	View

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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