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Human Disease and Mouse Model Detail
Human Disease Lung Cancer
OMIM ID: 211980
Human Phenotype Ontology associations
Synonyms Lung Cancer
View all models View ALL (47) mouse models for this human disease.
Genes and
mouse models
Mutations in human and/or mouse homologs are associated with this disease

      *Disease is associated/modeled with this Gene or a homolog. More...
      Human Homologs Mouse Homologs Mouse Models Homology Source
     KRAS* Kras* View 18 models HomoloGene and HGNC
     FGF9 Fgf9* View 1 model HomoloGene and HGNC
FOXM1 Foxm1* View 1 model HomoloGene and HGNC
ROBO1 Robo1* View 1 model HomoloGene and HGNC
XPC Xpc* View 2 models HomoloGene and HGNC
     BRAF* Braf   HomoloGene and HGNC
CASP8* Casp8   HomoloGene and HGNC
CYP2A6*, CYP2A7, CYP2A13 Cyp2a4, Cyp2a5   HomoloGene and HGNC
DLEC1* Dlec1   HomoloGene and HGNC
EGFR* Egfr View 4 models HomoloGene and HGNC
ERBB2* Erbb2   HomoloGene and HGNC
ERCC6* Ercc6   HomoloGene and HGNC
FASLG* Fasl   HomoloGene and HGNC
IRF1* Irf1   HomoloGene and HGNC
MAP3K8* Map3k8   HomoloGene and HGNC
PARK2* Park2   HomoloGene and HGNC
PIK3CA* Pik3ca View 1 model HomoloGene and HGNC
PPP2R1B* Ppp2r1b   HomoloGene and HGNC
RASSF1* Rassf1   HomoloGene and HGNC
SLC22A18* Slc22a18   HomoloGene and HGNC
Transgenes and
other genome features
Transgenes and other genome features developed in mice to model this disease.

     Transgenes and Other Genome Features Mouse Models
  Tg(Actb-KRAS*G12V,-luc)#Lche View 1 model
  Tg(SFTPC-CD74/ROS1)125Tno View 1 model
  Tg(SFTPC-EGFR*L858R)4-3Kkiu View 1 model
  Tg(SFTPC-EML4/ALK)502-4Hima View 1 model
  Tg(SFTPC-env)1Yhch View 1 model
  Tg(SFTPC-EZR/ROS1)AShiba View 1 model
  Tg(SFTPC-KIF5B/RET)1Tkoh View 1 model
  Tg(SFTPC-SDC4/ROS1)141Tno View 1 model
  Tg(tetO-EGFR*delta19)11Hev View 1 model
  Tg(tetO-EGFR*L858R)56Hev View 1 model
  Tg(tetO-EGFR*L858R)57Hev View 1 model
  Tg(tetO-EGFR*L858R)#Hev View 1 model
  Tg(tetO-EGFR*T790M)8Paow View 1 model
  Tg(tetO-EGFR*T790M*L858R)19Kkw View 1 model
  Tg(tetO-EGFR*T790M*L858R)51Paow View 1 model
  Tg(tetO-Fgf9,-EGFP)#Dor View 1 model
  Tg(tetO-PIK3CA*H1047R)13Lca View 1 model
  Tg(tetO-PTPN11*E76K)#Jiwu View 1 model
  Tg(Utg-TAg)7593Fjd View 1 model
  Tg(Utg-TAg)7736Fjd View 1 model
  Tg(Utg-TAg)#Fjd View 1 model
References Disease References using Mouse Models (64)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.07
The Jackson Laboratory