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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Tcrd
T cell receptor delta chain
MGI:98611
56 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Atg16l1tm1c(EUCOMM)Wtsi/Atg16l1tm1c(EUCOMM)Wtsi
Tcrdtm1Mom/Tcrdtm1Mom
Tg(Vil1-cre)997Gum/0
involves: 129P2/OlaHsd * C57BL/6J * C57BL/6N * SJL 		abnormal cytokine level J:340266
abnormal Paneth cell morphology J:340266
decreased Paneth cell number J:340266
decreased small intestinal villus height J:340266
increased small intestinal crypt cell apoptosis J:340266
increased susceptibility to colitis induced morbidity/mortality J:340266
Gt(ROSA)26Sortm10(Lmp1)Rsky/Gt(ROSA)26Sor+
Tcrbtm1Mom/Tcrb+
Tcrdtm1Mom/Tcrdtm1Mom
Cd19tm1(cre)Cgn/Cd19+
involves: 129P2/OlaHsd * 129S2/SvPas * BALB/cJ 		enlarged spleen J:181546
increased B cell number J:181546
premature death J:181546
Gt(ROSA)26Sortm10(Lmp1)Rsky/Gt(ROSA)26Sor+
Tcrbtm1Mom/Tcrbtm1Mom
Tcrdtm1Mom/Tcrdtm1Mom
Cd19tm1(cre)Cgn/Cd19+
involves: 129P2/OlaHsd * 129S2/SvPas * BALB/cJ 		enlarged liver J:181546
enlarged spleen J:181546
increased B cell derived lymphoma incidence J:181546
increased B cell number J:181546
increased plasmacytoma incidence J:181546
premature death J:181546
Gt(ROSA)26Sortm11(Lmp1)Rsky/Gt(ROSA)26Sor+
Tcrbtm1Mom/Tcrb+
Tcrdtm1Mom/Tcrdtm1Mom
Cd19tm1(cre)Cgn/Cd19+
involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6 		enlarged spleen J:181546
increased B cell number J:181546
premature death J:181546
Gt(ROSA)26Sortm11(Lmp1)Rsky/Gt(ROSA)26Sor+
Tcrbtm1Mom/Tcrbtm1Mom
Tcrdtm1Mom/Tcrdtm1Mom
Cd19tm1(cre)Cgn/Cd19+
involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6 		enlarged liver J:181546
enlarged spleen J:181546
increased B cell derived lymphoma incidence J:181546
increased B cell number J:181546
increased plasmacytoma incidence J:181546
premature death J:181546
H2b/H2b
Tcra/Tcrdtm1.1(Tcra)Rsky/Tcra/Tcrdtm1.1(Tcra)Rsky
Tg(Tcrb)93Vbo/?
involves: 129P2/OlaHsd * C57BL/6J * DBA/2J 		abnormal negative T cell selection J:81564
abnormal T cell differentiation J:81564
Itktm1Ljb/Itktm1Ljb
Tcrdtm1Mom/Tcrdtm1Mom
involves: 129 * C57BL/6 * C57BL/10 		normal immune system phenotype J:148531
Pigrtm1Ohw/Pigrtm1Ohw
Tcrbtm1Mom/Tcrbtm1Mom
Tcrdtm1Mom/Tcrdtm1Mom
involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6J 		decreased lymphocyte cell number J:97824
normal immune system phenotype J:97824
increased IgA level J:97824
Rr149356tm1Che/Rr149356tm1Che
Tcrdtm1Mom/Tcrdtm1Mom
Trp53tm1Tyj/Trp53tm1Tyj
involves: 129P2/OlaHsd * 129S2/SvPas * 129S4/SvJae * C57BL/6 		abnormal double-negative T cell morphology J:106246
increased T cell derived lymphoma incidence J:106246
Tcratm1Mom/Tcra/Tcrdtm1.1(Tcra)Rsky
H2b/H2b
Tg(Tcrb)93Vbo/?
involves: 129P2/OlaHsd * C57BL/6J * DBA/2J 		abnormal double-negative T cell morphology J:131357
abnormal double-positive T cell morphology J:81564
abnormal negative T cell selection J:81564
abnormal T cell differentiation J:81564
decreased double-positive T cell number J:131357
decreased thymocyte number J:131357
Tcratm1Mom/Tcra/Tcrdtm1.1(Tcra)Rsky
H2d/H2d
Ptcratm1Vbo/Ptcratm1Vbo
Tg(Tcrb)93Vbo/?
involves: 129P2/OlaHsd * C57BL/6J * DBA/2J 		abnormal T cell differentiation J:131357
decreased thymocyte number J:131357
Tcrbtm1Mom/Tcrbtm1Mom
Tcrdtm1Mom/Tcrdtm1Mom
B6.129P2-Tcrbtm1Mom Tcrdtm1Mom/J 		abnormal respiratory system physiology J:125656
abnormal transitional stage B cell morphology J:187766
decreased autoantibody level J:187766
decreased IgE level J:125656
decreased IgG1 level J:125656
decreased IgG level J:125656, J:187766
decreased plasma cell number J:187766
decreased T cell number J:187766
increased B cell number J:187766
increased follicular B cell number J:187766
increased IgM level J:187766
increased immature B cell number J:187766
increased marginal zone B cell number J:187766
increased mature B cell number J:187766
increased transitional stage T2 B cell number J:187766
increased transitional stage T3 B cell number J:187766
renal glomerular immunoglobulin deposits J:187766
Tcrbtm1Mom/Tcrbtm1Mom
Tcrdtm1Mom/Tcrdtm1Mom
FVB.129P2-Tcrbtm1Mom Tcrdtm1Mom 		normal immune system phenotype J:75915
Tcrbtm1Mom/Tcrbtm1Mom
Tcrdtm1Mom/Tcrdtm1Mom
involves: 129 * BALB/c * C57BL/6 		absent CD4-positive, alpha-beta T cells J:3206
absent CD8-positive, alpha-beta T cells J:3206
arrested T cell differentiation J:3206
colitis J:15221
decreased double-positive T cell number J:3206
thymus hypoplasia J:3206
Tcrbtm1Mom/Tcrbtm1Mom
Tcrdtm1Mom/Tcrdtm1Mom
involves: 129P2/OlaHsd 		decreased IgA level J:97824
decreased lymphocyte cell number J:97824
normal immune system phenotype J:97824
increased T cell number J:97824
Tcrbtm1Mom/Tcrbtm1Mom
Tcrdtm1Mom/Tcrdtm1Mom
involves: 129P2/OlaHsd * C57BL/6 		abnormal respiratory system morphology J:119344
abnormal respiratory system physiology J:119344
abnormal response to infection J:119344
decreased IgG level J:119344
normal immune system phenotype J:126867
Tcrbtm1Mom/Tcrbtm1Mom
Tcrdtm1Mom/Tcrdtm1Mom
Igh-Jtm2(3H9-VDJ*)Mwg/Igh-J+
B6.129P2-Tcrbtm1Mom Igh-Jtm2(3H9-VDJ*)Mwg Tcrdtm1Mom 		increased anti-double stranded DNA antibody level J:142389
increased marginal zone B cell number J:142389
spleen hypoplasia J:142389
Tcrbtm1Mom/Tcrbtm1Mom
Tcrdtm1Mom/Tcrdtm1Mom
Traf3ip2tm1.1Lix/Traf3ip2tm1.1Lix
B6.129-Tcrbtm1Mom Traf3ip2tm1.1Lix Tcrdtm1Mom 		abnormal glomerular capillary morphology J:187766
abnormal transitional stage B cell morphology J:187766
decreased IgG level J:187766
decreased T cell number J:187766
normal immune system phenotype J:187766
increased anti-chromatin antibody level J:187766
increased anti-double stranded DNA antibody level J:187766
increased anti-histone antibody level J:187766
increased autoantibody level J:187766
increased IgM level J:187766
increased immature B cell number J:187766
increased marginal zone B cell number J:187766
increased mesangial cell number J:187766
renal glomerular immunoglobulin deposits J:187766
Tcrdtm1Mom/Tcrdtm1Mom
Tcrgtm2.1Dhr/Tcrgtm2.1Dhr
involves: 129 * C57BL/6 		abnormal T cell receptor gamma chain V-J recombination J:75624
Tcrdtm1Mom/Tcrdtm1Mom
Tnftm2Gkl/Tnf+
involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6J 		small intestinal inflammation J:108572
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory