Slc2a1^tm1.1Stma
Targeted Allele Detail

Summary

• Symbol: Slc2a1^tm1.1Stma
• Name: solute carrier family 2 (facilitated glucose transporter), member 1; targeted mutation 1.1, Steven M Anderson
• MGI ID: MGI:5293720
• Synonyms: GLUT1^fl
• Gene: Slc2a1 Location: Chr4:118965942-118994527 bp, + strand
• Alliance: Slc2a1^tm1.1Stma page

Schematic representation of the Slc2a1 gene, the targeting vector and the recombinant allele Slc2a1^tm1.1Stma

Show the 1 phenotype image(s) involving this allele.

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:176530
• Parent Cell Line: W9.5/W95 (ES Cell)
• Strain of Origin: 129S1/Sv-Oca2⁺ Tyr⁺ Kitl⁺

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 3. An FRT-flanked neo cassette with a 3' loxP site was inserted downstream of exon 8. Flp-mediated recombination removed the neo cassette and left exons 3 through 8 floxed. (J:176530)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Slc2a1 Mutation: 60 strains or lines available

References

• Original: J:176530 Young CD, et al., Modulation of glucose transporter 1 (GLUT1) expression levels alters mouse mammary tumor cell growth in vitro and in vivo. PLoS One. 2011;6(8):e23205
• All: 30 reference(s)