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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Pax7
paired box 7
MGI:97491
58 phenotypes from multigenic genotypes
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
\2310065F04Riktm1.1Boet/\2310065F04Riktm1.1Boet
\Ino80tm1.1Jland/\Ino80tm1.1Jland
\Pax7tm1(cre)Mrc/\Pax7+
involves: 129S1/Sv * 129X1/SvJ 		normal growth/size/body region phenotype J:306156
normal muscle phenotype J:306156
\2310065F04Riktm1.1Boet/\2310065F04Riktm1.1Boet
\Ino80tm1.1Jland/\Ino80tm1.1Jland
\Pax7tm1(cre/ERT2)Gaka/\Pax7+
involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6NCrl 		normal muscle phenotype J:306156
\Abcc6tm1c(EUCOMM)Wtsi/\Abcc6tm1c(EUCOMM)Wtsi
\Pax7tm1(cre)Mrc/?
B6.Cg-Pax7tm1(cre)Mrc Abcc6tm1c(EUCOMM)Wtsi 		normal integument phenotype J:252837
\Artm2Ska/\Artm2Ska
\Pax7tm2.1(cre/ERT2)Fan/\Pax7+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6NCrlj * CBA/JNCrl 		normal muscle phenotype J:316008
\Cdkn2atm1Cjs/\Cdkn2atm1Cjs
\Pax7tm1Pgr/\Pax7+
\Tg(CKMM-tTA)A3Rhvh/0
\Tg(tetO-Hgf,-EGFP)24Tcre/0
involves: 129S2/SvPas * 129X1/SvJ * FVB 		increased rhabdomyosarcoma incidence J:237183
increased sarcoma incidence J:237183
\Cdkn2atm1Cjs/\Cdkn2atm1Cjs
\Pax7tm1Pgr/\Pax7tm1Pgr
\Tg(CKMM-tTA)A3Rhvh/0
\Tg(tetO-Hgf,-EGFP)24Tcre/0
involves: 129S2/SvPas * 129X1/SvJ * FVB 		increased rhabdomyosarcoma incidence J:237183
increased sarcoma incidence J:237183
\Dbx1tm1(DTA)Apie/\Dbx1+
\Pax7tm1(cre)Mrc/\Pax7+
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6 		normal nervous system phenotype J:165285
\Gt(ROSA)26Sortm1(EYFP)Cos/\Gt(ROSA)26Sortm1(EYFP)Cos
\Pax7tm1(cre/ERT2)Gaka/\Pax7tm1(cre/ERT2)Gaka
\Paxbp1tm1.1Nju/\Paxbp1tm1.1Nju
involves: 129S6/SvEvTac * 129X1/SvJ * C57BL/6NCr 		abnormal mitochondrial ATP synthesis coupled electron transport J:304562
abnormal mitochondrial morphology J:304562
abnormal oxidative phosphorylation J:304562
abnormal respiratory electron transport chain J:304562
decreased mitochondrial fission J:304562
impaired skeletal muscle regeneration J:304562
\Gt(ROSA)26Sortm1.1(DUX4*)Plj/\Gt(ROSA)26Sor+
\Pax7tm1(cre/ERT2)Gaka/?
involves: 129S6/SvEvTac * C57BL/6 * C57BL/6NCrl 		no abnormal phenotype detected J:256652
\Gt(ROSA)26Sortm1Sor/\Gt(ROSA)26Sor+
\Pax7tm1.1Fan/\Pax7tm2.1(cre/ERT2)Fan
involves: 129 * C57BL/6 * SJL 		abnormal muscle regeneration J:150962
abnormal myogenesis J:150962
normal muscle phenotype J:150962
\Gt(ROSA)26Sortm2(SS18)Mrc/\Gt(ROSA)26Sortm2(SS18)Mrc
\Pax7tm1(cre)Mrc/\Pax7tm1(cre)Mrc
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		lethality throughout fetal growth and development, complete penetrance J:120967
\Gt(ROSA)26Sortm3(SS18/EGFP)Mrc/\Gt(ROSA)26Sortm3(SS18/EGFP)Mrc
\Pax7tm1(cre)Mrc/\Pax7tm1(cre)Mrc
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		abnormal muscle development J:120967
lethality throughout fetal growth and development, complete penetrance J:120967
\Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/\Gt(ROSA)26Sor+
\Kdm6atm1.1Kaig/Y
\Pax7tm2.1(cre/ERT2)Fan/\Pax7+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		impaired skeletal muscle regeneration J:232700
\Gt(ROSA)26Sortm4(EWSR1/ATF1)Mrc/\Gt(ROSA)26Sor+
\Pax7tm1(cre)Mrc/\Pax7+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		abnormal craniofacial morphology J:194308
lethality throughout fetal growth and development, complete penetrance J:194308
\Gt(ROSA)26Sortm4(EWSR1/ATF1)Mrc/\Gt(ROSA)26Sor+
\Pax7tm1(cre/ERT2)Gaka/\Pax7+
involves: 129S6/SvEvTac * C57BL/6 		myopathy J:194308
normal neoplasm J:194308
\Ino80tm1.1Jland/\Ino80tm1.1Jland
\Pax7tm1(cre)Mrc/\Pax7+
involves: 129S1/Sv * 129X1/SvJ 		normal muscle phenotype J:306156
\Kdm6atm1.1Kaig/\Kdm6atm1.1Kaig
\Pax7tm2.1(cre/ERT2)Fan/\Pax7+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		abnormal muscle precursor cell morphology J:232700
impaired skeletal muscle regeneration J:232700
\Kdm6atm1.1Kaig/Y
\Pax7tm2.1(cre/ERT2)Fan/\Pax7+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		abnormal muscle precursor cell morphology J:232700
impaired skeletal muscle regeneration J:232700
\Krastm4Tyj/\Kras+
\Pax7tm2.1(cre/ERT2)Fan/\Pax7+
\Trp53tm1Brn/\Trp53tm1Brn
involves: 129/Sv * 129P2/OlaHsd * 129X1/SvJ * C57BL/6 		increased sarcoma incidence J:205518
increased tumor incidence J:205518
\Mamstrtm1.1Eno/\Mamstrtm1.1Eno
\Pax7tm2.1(cre/ERT2)Fan/\Pax7+
involves: 129 * C57BL/6 		impaired skeletal muscle regeneration J:179880
\Myf5tm1(cre)Mrc/\Myf5+
\Myod1tm1Jae/\Myod1tm1Jae
\Pax7tm1.1Thbr/\Pax7tm1.1Thbr
involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ 		decreased satellite cell number J:202693
\Myf5tm1Tajb/\Myf5tm1Tajb
\Pax7tm1.1Tajb/\Pax7tm1.1Tajb
involves: 129S2/SvPas 		abnormal extraocular muscle morphology J:150130
normal muscle phenotype J:150130
\Myh3tm1.2Sajm/\Myh3tm1.1Sajm
\Pax7tm1(cre)Mrc/\Pax7+
involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ * C57BL/6J 		abnormal muscle precursor cell morphology J:287755
normal cellular phenotype J:287755
\Pax3tm1.1Sjc/\Pax3tm1.1Sjc
\Pax7tm1.2Fan/\Pax7tm1.2Fan
\Tg(CAG-cre/Esr1*)5Amc/0
involves: 129 * C57BL/6 * CBA * SJL 		normal muscle phenotype J:150962
\Pax3tm1Buck/\Pax3tm1Buck
\Pax7tm2Pgr/\Pax7tm2Pgr
either: (involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ) or (involves: 129P2/OlaHsd * 129S2/SvPas) 		abnormal myotome development J:99365
prenatal lethality, complete penetrance J:99365
\Pax3tm1Mrc/\Pax3+
\Pax7tm1(cre)Mrc/\Pax7+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		abnormal nose morphology J:93443
abnormal premaxilla morphology J:93443
decreased body weight J:93443
decreased satellite cell number J:93443
decreased skeletal muscle fiber diameter J:93443
decreased skeletal muscle mass J:93443
increased skeletal muscle fiber density J:93443
lacrimal bone hypoplasia J:93443
maxilla hypoplasia J:93443
muscle hypoplasia J:93443
normal neoplasm J:93443
postnatal growth retardation J:93443
premature death J:93443
turbinate hypoplasia J:93443
\Pax7tm1(cre)Mrc/\Pax7+
\Styxl2tm1Nju/\Styxl2tm1Nju
involves: 129S1/Sv * 129X1/SvJ 		abnormal sarcomere morphology J:351096
abnormal skeletal muscle morphology J:351096
cyanosis J:351096
neonatal lethality, complete penetrance J:351096
primary atelectasis J:351096
\Pax7tm1(cre)Mrc/\Pax7tm1(cre)Mrc
\Paxbp1tm1.1Nju/\Paxbp1tm1.1Nju
involves: 129S1/Sv * 129X1/SvJ 		embryonic lethality, complete penetrance J:304562
\Pax7tm1(cre/ERT2)Gaka/\Pax7+
\Gt(ROSA)26Sortm1(DTA)Mrc/\Gt(ROSA)26Sor+
involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 		decreased satellite cell number J:174914
impaired skeletal muscle regeneration J:174914
skeletal muscle fibrosis J:174914
\Pax7tm1(cre/ERT2)Gaka/\Pax7tm1(cre/ERT2)Gaka
\Styxl2tm1Nju/\Styxl2tm1Nju
involves: 129S * C57BL/6 		abnormal sarcomere morphology J:351096
impaired skeletal muscle contractility J:351096
impaired skeletal muscle regeneration J:351096
\Pax7tm1(cre/ERT2)Gaka/0
\Snhg15tm1.1Nju/\Snhg15tm1.1Nju
involves: C57BL/6J * SJL/J 		delayed skeletal muscle regeneration J:291983
\Pax7tm1.1(HBEGF,-EYFP)Mal/\Pax7+
involves: C57BL/6 		decreased skeletal muscle mass J:180899
impaired skeletal muscle regeneration J:180899
normal muscle phenotype J:180899
myositis J:180899
\Pax7tm1.1(HBEGF,-EYFP)Mal/\Pax7+
\Tg(Pax7-EGFP)15Tajb/0
involves: C57BL/6 * SJL/J 		abnormal muscle regeneration J:180899
decreased satellite cell number J:180899
\Pax7tm1.1(HBEGF,-EYFP)Mal/\Pax7tm1.1(HBEGF,-EYFP)Mal
involves: C57BL/6 		decreased birth body size J:180899
premature death J:180899
\Pax7tm1.1(rtTA)Sjl/\Pax7tm1.1(rtTA)Sjl
\Tg(Myl1-FST)F66Sjl/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL 		abnormal skeletal muscle fiber size J:188599
increased skeletal muscle weight J:188599
\Prmt7tm1.1Rchd/\Prmt7tm1.1Rchd
\Pax7tm1(cre/ERT2)Gaka/\Pax7+
involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6NCrl 		abnormal muscle physiology J:271361
abnormal response to injury J:271361
early cellular replicative senescence J:271361
impaired skeletal muscle regeneration J:271361
\Ptch1tm1Cklr/\Ptch1+
\Trp53tm1Brn/?
\Pax7tm1(cre)Mrc/\Pax7+
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL 		increased medulloblastoma incidence J:159972
\Ptch1tm1Cklr/\Ptch1+
\Pax7tm1(cre)Mrc/\Pax7+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL 		ataxia J:159972
increased medulloblastoma incidence J:159972
\Six1tm2.1Mair/\Six1tm2.1Mair
\Pax7tm1(cre/ERT2)Gaka/\Pax7+
involves: 129S6/SvEvTac * C57BL/6 * C57BL/6Cr * C57BL/6NTac 		abnormal muscle physiology J:190460
abnormal muscle regeneration J:190460
normal muscle phenotype J:190460
skeletal muscle fibrosis J:190460
\Zfp422em1Mode/\Zfp422em1Mode
\Pax7tm1(cre/ERT2)Gaka/\Pax7+
involves: 129S6/SvEvTac * C57BL/6J * C57BL/6NCrl 		abnormal myoblast differentiation J:297035
impaired skeletal muscle regeneration J:297035
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory