Pax7^tm1.1Fan
Targeted Allele Detail

Summary

• Symbol: Pax7^tm1.1Fan
• Name: paired box 7; targeted mutation 1.1, Chen-Ming Fan
• MGI ID: MGI:4353118
• Synonyms: Pax7^f, Pax7^loxP-Le
• Gene: Pax7 Location: Chr4:139464373-139560839 bp, - strand Genetic Position: Chr4, 70.83 cM
• Alliance: Pax7^tm1.1Fan page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:150962
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 2 and an frt flanked neo cassette with a 3' loxP site was inserted downstream of exon 2. The neo cassette was removed by flp mediated recombination leaving exon 2 floxed. (J:150962)

Tumor Data

List all tumor models in MMHCdb carrying Pax7^tm1.1Fan

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Pax7 Mutation: 39 strains or lines available

References

• Original: J:150962 Lepper C, et al., Adult satellite cells and embryonic muscle progenitors have distinct genetic requirements. Nature. 2009 Jul 30;460(7255):627-31
• All: 10 reference(s)