79 phenotypes from 4 alleles in 15 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Myf5tm3(cre)Sor/Myf5+ Stat5btm1Mam/Stat5btm1Mam involves: 129S4/SvJaeSor * 129S6/SvEvTac	decreased body length	J:119237
	decreased body weight	J:119237
	decreased circulating insulin-like growth factor I level	J:119237
	decreased lean body mass	J:119237
	impaired glucose tolerance	J:119237
	increased circulating triglyceride level	J:119237
	increased total body fat amount	J:119237
Myf5tm3(cre)Sor/Myf5+ Stat5btm1Mam/Stat5btm1Mam Tg(Alb1-cre)1Dlr/0 involves: 129S4/SvJaeSor * 129S6/SvEvTac * FVB/N	decreased body length	J:119237
	decreased body weight	J:119237
	decreased circulating insulin-like growth factor I level	J:119237
	decreased lean body mass	J:119237
	increased total body fat amount	J:119237
Stat5btm1Hwd/Stat5btm1Hwd involves: 129 * BALB/c	abnormal hair growth	J:41784
	abnormal liver physiology	J:41784
	abnormal mammary gland development	J:41784
	decreased body weight	J:41784
	decreased circulating insulin-like growth factor I level	J:41784
	decreased total body fat amount	J:41784
	decreased urine major urinary protein level	J:41784
	enlarged liver	J:41784
	hypolactation	J:41784
	increased circulating growth hormone level	J:41784
	increased miscarriage rate	J:41784
	obese	J:41784
	pale liver	J:41784
	sparse hair	J:41784
Stat5btm1Hwd/Stat5btm1Hwd involves: C57BL/6	abnormal double-negative T cell morphology	J:112035
	abnormal lymphocyte cell number	J:112035
	abnormal lymphocyte morphology	J:112035
	decreased CD8-positive, alpha-beta T cell number	J:112035
	decreased NK cell number	J:112035
	decreased splenocyte number	J:112035
	decreased T cell proliferation	J:112035
	decreased thymocyte number	J:112035
	impaired natural killer cell mediated cytotoxicity	J:112035
Stat5btm1Jni/Stat5btm1Jni either: (involves: 129P2/OlaHsd) or (involves: 129X1/SvJ)	abnormal fat pad morphology	J:77412
	abnormal liver physiology	J:77412
	abnormal mammary gland physiology	J:77412
	decreased body weight	J:77412
Stat5btm1Mam/Stat5btm1Mam involves: 129S6/SvEvTac * Black Swiss	no abnormal phenotype detected	J:92770
Stat5btm1Mam/Stat5btm1Mam Tg(Alb1-cre)7Gsc/0 involves: 129S6/SvEvTac * FVB/N	decreased body weight	J:121556
Stat5btm1Mam/Stat5btm1Mam Tg(Cd4-cre)1Cwi/0 involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * DBA/2	increased circulating interleukin-17 level	J:120176
	increased interleukin-17 secretion	J:120176
Stat5btm1Mam/Stat5btm1Mam Tg(Ins2-cre)25Mgn/0 involves: 129S6/SvEvTac * C57BL/6 * DBA	decreased insulin secretion	J:127051
	disorganized pancreatic islets	J:127051
	impaired glucose tolerance	J:127051
	increased circulating free fatty acids level	J:127051
	increased circulating glucose level	J:127051
	increased circulating leptin level	J:127051
	increased total body fat amount	J:127051
	obese	J:127051
Stat5btm1Mam/Stat5btm1Mam Tg(Lck-cre)I57Jxm/0 involves: 129 * 129S6/SvEvTac * C57BL/6 * ICR	abnormal acute inflammation	J:122463
	abnormal T cell subpopulation ratio	J:122463
	decreased CD8-positive, alpha-beta T cell number	J:122463
	enlarged spleen	J:122463
Stat5btm1Mam/Stat5btm1Mam Tg(MMTV-cre)1Mam/0 involves: 129S6/SvEvTac * FVB/N	abnormal mammary gland alveolus morphology	J:153755
	abnormal mammary gland growth during lactation	J:153755
	lactation failure	J:153755
Stat5btm1Mam/Stat5btm1Mam Tg(MMTV-cre)4Mam/0 involves: 129S6/SvEvTac * Black Swiss * FVB	abnormal branching of the mammary ductal tree	J:92770
	abnormal milk ejection	J:92770
Stat5btm1Mam/Stat5btm1Mam Tg(Mx1-cre)1Cgn/0 involves: 129S6/SvEvTac * C57BL/6 * CBA	abnormal leukopoiesis	J:155489
	abnormal neutrophil differentiation	J:155489
	abnormal neutrophil physiology	J:155489
	anemia	J:155489
	decreased cell proliferation	J:155489
	decreased erythrocyte cell number	J:155489
	decreased hematocrit	J:155489
	decreased hemoglobin content	J:155489
	decreased leukocyte cell number	J:155489
	decreased lymphocyte cell number	J:155489
	decreased monocyte cell number	J:155489
	decreased neutrophil cell number	J:155489
	increased apoptosis	J:155489
Stat5btm1Mam/Stat5btm1Mam Tg(Nes-cre)1Kln/0 involves: 129 * 129S6/SvEvTac * C57BL/6 * SJL	abnormal fat pad morphology	J:132806
	decreased oxygen consumption	J:132806
	impaired adaptive thermogenesis	J:132806
	impaired glucose tolerance	J:132806
	increased circulating free fatty acids level	J:132806
	increased circulating insulin level	J:132806
	increased circulating leptin level	J:132806
	increased circulating triglyceride level	J:132806
	increased lean body mass	J:132806
	increased percent body fat/body weight	J:132806
	increased total body fat amount	J:132806
	increased total fat pad weight	J:132806
	insulin resistance	J:132806
	obese	J:132806
	polyphagia	J:132806
Stat5btm1Mam/Stat5btm1Mam Tg(Pdx1-cre)89.1Dam/0 involves: 129S6/SvEvTac * C57BL/6 * CBA	disorganized pancreatic islets	J:127051
	impaired glucose tolerance	J:127051
Stat5btm1Mam/Stat5btm1Mam Tg(Tek-cre)1Ywa/0 involves: 129S6/SvEvTac * C57BL/6 * SJL	abnormal proerythroblast morphology	J:138904
	anisocytosis	J:138904
	decreased erythrocyte cell number	J:138904
	decreased erythroid progenitor cell number	J:138904
	decreased hematocrit	J:138904
	decreased mean corpuscular hemoglobin	J:138904
	hypochromic microcytic anemia	J:138904
	increased apoptosis	J:138904
	increased circulating iron level	J:138904
	increased liver iron level	J:138904
	increased red blood cell distribution width	J:138904
	microcytosis	J:138904
	poikilocytosis	J:138904
	reticulocytosis	J:138904
Stat5btm1Mam/Stat5btm1Mam Tg(Wap-cre)11738Mam/0 involves: 129S6/SvEvTac * Black Swiss	abnormal mammary gland alveolus morphology	J:92770
	increased mammary gland apoptosis	J:92770
Stat5btm2.1Wjl/Stat5btm2.1Wjl involves: 129S6/SvEvTac * C57BL/6J * FVB/N	no abnormal phenotype detected	J:187325