Rhox Complex/Cluster/Region Detail

Summary

• Symbol
  Rhox
• Name
  reproductive homeobox cluster

• Feature Type
  complex/cluster/region
• IDs
  MGI:5763243
• Cluster Members
  Rhox1, Rhox2a, Rhox3a ... (41 members)

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome X, Syntenic

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  4 phenotypes from 1 allele in 1 genetic background
  4 phenotypes from multigenic genotypes
  3 phenotype references
  

• All Mutations and Alleles
  2
• Targeted
  2
• Find Mice (IMSR)
  1 strains or lines available

Mice homozygous for a knock-out allele of the cluster exhibit a modest impact on testes size, male germ cell numbers and seminiferous tubule diameter.

References

• Summaries
  All 4

  Phenotypes 3
• Earliest
  J:229199 Song HW, et al., shRNA off-target effects in vivo: impaired endogenous siRNA expression and spermatogenic defects. PLoS One. 2015;10(3):e0118549
• Latest
  J:306454 Tan K, et al., The Rhox gene cluster suppresses germline LINE1 transposition. Proc Natl Acad Sci U S A. 2021 Jun 8;118(23):e2024785118

Rhox Cluster contains:

More Data for these features

Member	Feature Type	Location
Rhox1, reproductive homeobox 1	protein coding gene	ChrX:36477457-36485911 (-)
Rhox2a, reproductive homeobox 2A	protein coding gene	ChrX:36508645-36513343 (+)
Rhox3a, reproductive homeobox 3A	protein coding gene	ChrX:36513572-36522631 (+)
Rhox4a, reproductive homeobox 4A	protein coding gene	ChrX:36528991-36533785 (+)
Rhox3a2, reproductive homeobox 3A2	protein coding gene	ChrX:36562036-36566141 (+)
Rhox4a2, reproductive homeobox 4A2	protein coding gene	ChrX:36572513-36577274 (+)
Rhox2b, reproductive homeobox 2B	protein coding gene	ChrX:36593720-36598459 (+)
Rhox3b-ps, reproductive homeobox 3B, pseudogene	pseudogene	ChrX:36598665-36607616 (+)
Rhox4b, reproductive homeobox 4B	protein coding gene	ChrX:36614147-36618931 (+)
Rhox2c, reproductive homeobox 2C	protein coding gene	ChrX:36635133-36640049 (+)
Rhox3c, reproductive homeobox 3C	protein coding gene	ChrX:36651521-36655614 (+)
Rhox4c, reproductive homeobox 4C	protein coding gene	ChrX:36661990-36666777 (+)
Rhox2d, reproductive homeobox 2D	protein coding gene	ChrX:36675081-36679276 (+)
Rhox3d-ps, reproductive homeobox 3D, pseudogene	pseudogene	ChrX:36685497-36689459 (+)
Rhox4d, reproductive homeobox 4D	protein coding gene	ChrX:36696038-36700829 (+)
Rhox2e, reproductive homeobox 2E	protein coding gene	ChrX:36712105-36723466 (+)
Rhox3e, reproductive homeobox 3E	protein coding gene	ChrX:36728628-36732550 (+)
Rhox4e, reproductive homeobox 4E	protein coding gene	ChrX:36739065-36743935 (+)
Rhox2f, reproductive homeobox 2F	protein coding gene	ChrX:36753074-36757812 (+)
Rhox3f, reproductive homeobox 3F	protein coding gene	ChrX:36763005-36767149 (+)
Rhox4f, reproductive homeobox 4F	protein coding gene	ChrX:36784548-36789339 (-)
Rhox3g, reproductive homeobox 3G	protein coding gene	ChrX:36805084-36809792 (-)
Rhox2g, reproductive homeobox 2G	protein coding gene	ChrX:36820768-36825123 (-)
Rhox4g, reproductive homeobox 4G	protein coding gene	ChrX:36828154-36832980 (-)
Rhox3h, reproductive homeobox 3H	protein coding gene	ChrX:36839341-36850417 (-)
Rhox2h, reproductive homeobox 2H	protein coding gene	ChrX:36850650-36854930 (-)
Rhox7-ps2, reproductive homeobox 7, pseudogene 2	pseudogene	ChrX:36858023-36861200 (-)
Rhox2-ps, reproductive homeobox 2, pseudogene	pseudogene	ChrX:36864574-36865084 (-)
Rhox5, reproductive homeobox 5	protein coding gene	ChrX:36891657-36897305 (+)
Rhox6, reproductive homeobox 6	protein coding gene	ChrX:36915932-36918734 (+)
Rhox7a, reproductive homeobox 7A	protein coding gene	ChrX:36920563-36930048 (+)
Rhox8, reproductive homeobox 8	protein coding gene	ChrX:36963655-36967821 (-)
Rhox7b, reproductive homeobox 7B	protein coding gene	ChrX:36975424-36986109 (-)
Rhox9, reproductive homeobox 9	protein coding gene	ChrX:36987974-36990647 (-)
Rhox11-ps1, reproductive homeobox 11, pseudogene 1	pseudogene	ChrX:37021351-37022360 (-)
Rhox11-ps2, reproductive homeobox 11, pseudogene 2	pseudogene	ChrX:37029693-37034479 (-)
Rhox10, reproductive homeobox 10	protein coding gene	ChrX:37155352-37160565 (+)
Rhox11, reproductive homeobox 11	protein coding gene	ChrX:37165475-37174016 (-)
Rhox11-ps3, reproductive homeobox 11, pseudogene 3	pseudogene	ChrX:37178719-37178951 (+)
Rhox12, reproductive homeobox 12	protein coding gene	ChrX:37192954-37199784 (-)
Rhox13, reproductive homeobox 13	protein coding gene	ChrX:37210096-37218844 (+)