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Tsc22d4 Gene Detail
Summary
  • Symbol
    Tsc22d4
  • Name
    Tsc22 domain family, member 4
  • Synonyms
    0610009M14Rik, 1700023B23Rik, Spacdr, Thg-1pit, Tsc22d4
  • Feature Type
    protein coding gene
  • IDs
    MGI:1926079
    NCBI Gene: 78829
  • Alliance
    gene page
  • Transcription Start Sites
    21 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:137744274-137758011 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 76.64 cM, cytoband G1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    6 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1926079
 protein coding gene Chr5:137743992-137766712 (+)
129S1/SvImJ MGP_129S1SvImJ_G0030242
 protein coding gene Chr5:142536207-142559967 (+)
A/J MGP_AJ_G0030210
 protein coding gene Chr5:136318627-136344370 (+)
AKR/J MGP_AKRJ_G0030143
 protein coding gene Chr5:140748935-140771476 (+)
BALB/cJ MGP_BALBcJ_G0030220
 protein coding gene Chr5:137706010-137728098 (+)
C3H/HeJ MGP_C3HHeJ_G0029936
 protein coding gene Chr5:141410815-141433805 (+)
C57BL/6NJ MGP_C57BL6NJ_G0030672
 protein coding gene Chr5:147803156-147826709 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0027890
 protein coding gene Chr5:130551218-130572422 (+)
CAST/EiJ MGP_CASTEiJ_G0029346
 protein coding gene Chr5:140801776-140828916 (+)
CBA/J MGP_CBAJ_G0029906
 protein coding gene Chr5:153689239-153711604 (+)
DBA/2J MGP_DBA2J_G0030057
 protein coding gene Chr5:136217920-136240438 (+)
FVB/NJ MGP_FVBNJ_G0030012
 protein coding gene Chr5:135421408-135445726 (+)
LP/J MGP_LPJ_G0030146
 protein coding gene Chr5:143015203-143040951 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0030044
 protein coding gene Chr5:156486738-156511138 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0030713
 protein coding gene Chr5:140604525-140628380 (+)
PWK/PhJ MGP_PWKPhJ_G0029059
 protein coding gene Chr5:135309103-135331536 (+)
SPRET/EiJ MGP_SPRETEiJ_G0028895
 protein coding gene Chr5:138171246-138192660 (+)
WSB/EiJ MGP_WSBEiJ_G0029419
 protein coding gene Chr5:141333138-141358595 (+)



Homology
more
  • Human Ortholog
    SPACDR, sperm acrosome developmental regulator
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SPACDR, sperm acrosome developmental regulator
  • Synonyms
    C7orf61
  • Links
    NCBI Gene ID: 402573
    neXtProt AC: NX_Q8IZ16
    UniProt: Q8IZ16

  • Chr Location
    7q22.1; chr7:100456620-100464260 (-)  GRCh38
  • Human Ortholog
    TSC22D4, TSC22 domain family member 4
  • Synonyms
    SPACDR, THG1, THG-1, TILZ2
  • Links
    NCBI Gene ID: 81628
    neXtProt AC: NX_Q9Y3Q8
    UniProt: Q9Y3Q8

  • Chr Location
    7q22.1; chr7:100463359-100479232 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    14
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    842
  • Tissues
    103
  • cDNA Data
    27
  • Literature Summary
    8
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 78829 NCBI Gene Model | MGI Sequence Detail 13738 C57BL/6J ±  kb
transcript NM_023910 RefSeq | MGI Sequence Detail 2308 C57BL/6  
polypeptide NP_076399 RefSeq | MGI Sequence Detail 387 C57BL/6  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 32
    cDNA 30
    Primer pair 2

    Microarray probesets 3
Other
Accession IDs
less
MGI:1924190, MGI:2140863
References
more
  • Summaries
    All 43
    Developmental Gene Expression 8
    Gene Ontology 9
    Phenotypes 3
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:345088 Demir S, et al., TSC22D4 interacts with Akt1 to regulate glucose metabolism. Sci Adv. 2022 Oct 21;8(42):eabo5555
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory