Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Tgfbr3

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes TGFBR3
- Mouse genes Tgfbr3
- Rat genes Tgfbr3
- Zfish genes tgfbr3
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tgfbr3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0048185	activin binding	Tgfbr3	IDA		Rat	PMID:12385827\|RGD:1579945
Molecular Function	GO:0015026	coreceptor activity	TGFBR3	IDA		Human	PMID:10746731
Molecular Function	GO:0017134	fibroblast growth factor binding	Tgfbr3	IDA		Rat	PMID:1556106\|RGD:1579950
Molecular Function	GO:0005539	glycosaminoglycan binding	Tgfbr3	IDA		Mouse	MGI:MGI:2663364\|PMID:12773577
Molecular Function	GO:0008201	heparin binding	Tgfbr3	IDA		Rat	PMID:8106553\|RGD:1579949
Molecular Function	GO:0030165	PDZ domain binding	Tgfbr3	IPI	UniProtKB:Q9Z0G0	Mouse	MGI:MGI:3807767\|PMID:11546783
Molecular Function	GO:0005515	protein binding	TGFBR3	IPI	UniProtKB:P05111	Human	PMID:10746731
Molecular Function	GO:0005515	protein binding	TGFBR3	IPI	UniProtKB:P01137	Human	PMID:10746731
Molecular Function	GO:0005515	protein binding	TGFBR3	IPI	UniProtKB:P61812	Human	PMID:11157754
Molecular Function	GO:0005515	protein binding	TGFBR3	IPI	UniProtKB:O14908	Human	PMID:11546783
Molecular Function	GO:0005515	protein binding	TGFBR3	IPI	UniProtKB:P32121	Human	PMID:12958365
Molecular Function	GO:0005515	protein binding	TGFBR3	IPI	UniProtKB:P12643	Human	PMID:18184661
Molecular Function	GO:0005515	protein binding	TGFBR3	IPI	UniProtKB:P18075	Human	PMID:18184661
Molecular Function	GO:0005515	protein binding	TGFBR3	IPI	UniProtKB:P01137	Human	PMID:20856203
Molecular Function	GO:0005515	protein binding	Tgfbr3	IPI	UniProtKB:P04202	Mouse	MGI:MGI:2663364\|PMID:12773577
Molecular Function	GO:0005515	protein binding	Tgfbr3	IPI	RGD:736727	Rat	PMID:16522726\|RGD:1579944
Molecular Function	GO:0005515	protein binding	Tgfbr3	IPI	UniProtKB:P61812	Rat	PMID:7852346\|RGD:8553463
Molecular Function	GO:0005515	protein binding	Tgfbr3	IPI	UniProtKB:P38438	Rat	PMID:8106553\|RGD:1579949
Molecular Function	GO:0046332	SMAD binding	TGFBR3	IMP		Human	PMID:11157754
Molecular Function	GO:0046332	SMAD binding	Tgfbr3	IMP		Mouse	MGI:MGI:3699491\|PMID:17295310
Molecular Function	GO:0050431	transforming growth factor beta binding	TGFBR3	IPI	UniProtKB:P61812	Human	PMID:11157754
Molecular Function	GO:0050431	transforming growth factor beta binding	TGFBR3	IDA		Human	PMID:11157754
Molecular Function	GO:0050431	transforming growth factor beta binding	TGFBR3	IDA		Human	PMID:12958365
Molecular Function	GO:0050431	transforming growth factor beta binding	Tgfbr3	IDA		Mouse	MGI:MGI:3699491\|PMID:17295310
Molecular Function	GO:0050431	transforming growth factor beta binding	Tgfbr3	IPI	UniProtKB:P61812	Rat	PMID:7852346\|RGD:8553463
Molecular Function	GO:0050431	transforming growth factor beta binding	Tgfbr3	IDA		Rat	PMID:1657407\|RGD:729942
Molecular Function	GO:0050431	transforming growth factor beta binding	Tgfbr3	IDA		Rat	PMID:1744125\|RGD:2302518
Molecular Function	GO:0050431	transforming growth factor beta binding	Tgfbr3	IDA		Rat	PMID:8106553\|RGD:1579949
Molecular Function	GO:0005024	transforming growth factor beta receptor activity	TGFBR3	IDA		Human	PMID:12958365
Molecular Function	GO:0005024	transforming growth factor beta receptor activity	Tgfbr3	IDA		Mouse	PMID:9659379
Molecular Function	GO:0005024	transforming growth factor beta receptor activity	Tgfbr3	IMP		Mouse	PMID:17823118
Molecular Function	GO:0070123	transforming growth factor beta receptor activity, type III	TGFBR3	IDA		Human	PMID:10746731
Molecular Function	GO:0070123	transforming growth factor beta receptor activity, type III	TGFBR3	IDA		Human	PMID:11157754
Molecular Function	GO:0070123	transforming growth factor beta receptor activity, type III	Tgfbr3	IDA		Rat	PMID:8106553\|RGD:1579949
Molecular Function	GO:0005160	transforming growth factor beta receptor binding	Tgfbr3	IDA		Rat	PMID:8106553\|RGD:1579949
Molecular Function	GO:0005114	type II transforming growth factor beta receptor binding	TGFBR3	IDA		Human	PMID:11157754
Cellular Component	GO:0009986	cell surface	Tgfbr3	IDA		Mouse	MGI:MGI:3807767\|PMID:11546783
Cellular Component	GO:0005737	cytoplasm	Tgfbr3	IDA		Mouse	PMID:18236212
Cellular Component	GO:0005737	cytoplasm	Tgfbr3	IDA		Mouse	PMID:9921650
Cellular Component	GO:0005737	cytoplasm	Tgfbr3	IDA		Rat	PMID:10207840\|RGD:1579948
Cellular Component	GO:0005783	endoplasmic reticulum	Tgfbr3	IDA		Mouse	PMID:9921650
Cellular Component	GO:0009897	external side of plasma membrane	TGFBR3	IDA		Human	PMID:12958365
Cellular Component	GO:0070062	extracellular exosome	TGFBR3	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	TGFBR3	HDA		Human	PMID:19199708
Cellular Component	GO:0031012	extracellular matrix	Tgfbr3	IDA		Rat	PMID:10207840\|RGD:1579948
Cellular Component	GO:0005615	extracellular space	TGFBR3	HDA		Human	PMID:16502470
Cellular Component	GO:0005615	extracellular space	Tgfbr3	IDA		Rat	PMID:2592419\|RGD:1579952
Cellular Component	GO:0034673	inhibin-betaglycan-ActRII complex	TGFBR3	IDA		Human	PMID:10746731
Cellular Component	GO:0016020	membrane	Tgfbr3	IDA		Rat	PMID:8106553\|RGD:1579949
Cellular Component	GO:0005886	plasma membrane	Tgfbr3	IDA		Rat	PMID:10207840\|RGD:1579948
Cellular Component	GO:0043235	receptor complex	TGFBR3	IDA		Human	PMID:11157754
Cellular Component	GO:0043235	receptor complex	Tgfbr3	IDA		Rat	PMID:7852346\|RGD:8553463
Biological Process	GO:0031100	animal organ regeneration	Tgfbr3	IEP		Rat	PMID:9699514\|RGD:2302035
Biological Process	GO:0060561	apoptotic process involved in morphogenesis	Tgfbr3	IMP		Mouse	PMID:25382630
Biological Process	GO:0001824	blastocyst development	Tgfbr3	IDA		Mouse	PMID:9921650
Biological Process	GO:0001568	blood vessel development	Tgfbr3	IMP	MGI:MGI:3818438	Mouse	PMID:17704211
Biological Process	GO:0001974	blood vessel remodeling	Tgfbr3	IMP		Mouse	PMID:25382630
Biological Process	GO:0030509	BMP signaling pathway	TGFBR3	IDA		Human	PMID:18184661
Biological Process	GO:0030509	BMP signaling pathway	Tgfbr3	IMP		Mouse	PMID:25382630
Biological Process	GO:0060317	cardiac epithelial to mesenchymal transition	TGFBR3	IDA		Human	PMID:18184661
Biological Process	GO:0060038	cardiac muscle cell proliferation	Tgfbr3	IMP		Mouse	MGI:MGI:2663364\|PMID:12773577
Biological Process	GO:0008283	cell population proliferation	Tgfbr3	IMP		Mouse	PMID:25382630
Biological Process	GO:0032963	collagen metabolic process	Tgfbr3	IGI	RNAcentral:URS000039ED8D_10090	Mouse	MGI:MGI:5688831\|PMID:22960625
Biological Process	GO:0060318	definitive erythrocyte differentiation	Tgfbr3	IMP		Mouse	MGI:MGI:2663364\|PMID:12773577
Biological Process	GO:0060216	definitive hemopoiesis	Tgfbr3	IMP		Mouse	MGI:MGI:2663364\|PMID:12773577
Biological Process	GO:0060939	epicardium-derived cardiac fibroblast cell development	Tgfbr3	IMP		Mouse	MGI:MGI:3818140\|PMID:17704211
Biological Process	GO:0001837	epithelial to mesenchymal transition	TGFBR3	IDA		Human	PMID:18184661
Biological Process	GO:0060347	heart trabecula formation	Tgfbr3	IMP		Mouse	MGI:MGI:2663364\|PMID:12773577
Biological Process	GO:0061384	heart trabecula morphogenesis	Tgfbr3	IMP		Mouse	MGI:MGI:2663364\|PMID:12773577
Biological Process	GO:0006955	immune response	TGFBR3	IMP		Human	PMID:16886151
Biological Process	GO:0001701	in utero embryonic development	Tgfbr3	IMP	MGI:MGI:3818438	Mouse	PMID:17704211
Biological Process	GO:0035556	intracellular signal transduction	TGFBR3	IMP		Human	PMID:14557487
Biological Process	GO:0001889	liver development	Tgfbr3	IMP		Mouse	MGI:MGI:2663364\|PMID:12773577
Biological Process	GO:0003150	muscular septum morphogenesis	Tgfbr3	IMP		Mouse	MGI:MGI:2663364\|PMID:12773577
Biological Process	GO:1902338	negative regulation of apoptotic process involved in morphogenesis	Tgfbr3	IMP		Mouse	PMID:25382630
Biological Process	GO:0010633	negative regulation of epithelial cell migration	Tgfbr3	IMP		Mouse	PMID:17823118
Biological Process	GO:0050680	negative regulation of epithelial cell proliferation	Tgfbr3	IMP		Mouse	MGI:MGI:3699491\|PMID:17295310
Biological Process	GO:0010719	negative regulation of epithelial to mesenchymal transition	Tgfbr3	IMP		Mouse	PMID:17823118
Biological Process	GO:0010629	negative regulation of gene expression	Tgfbr3	IDA		Mouse	MGI:MGI:5688831\|PMID:22960625
Biological Process	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway	Tgfbr3	IDA		Rat	PMID:10746731\|RGD:1579946
Biological Process	GO:0001649	osteoblast differentiation	Tgfbr3	IMP		Mouse	PMID:25382630
Biological Process	GO:0003151	outflow tract morphogenesis	Tgfbr3	IMP		Mouse	MGI:MGI:3818140\|PMID:17704211
Biological Process	GO:0060389	pathway-restricted SMAD protein phosphorylation	TGFBR3	IMP		Human	PMID:11157754
Biological Process	GO:0060389	pathway-restricted SMAD protein phosphorylation	Tgfbr3	IMP		Mouse	MGI:MGI:3699491\|PMID:17295310
Biological Process	GO:0030513	positive regulation of BMP signaling pathway	Tgfbr3	IMP		Mouse	PMID:25382630
Biological Process	GO:0060045	positive regulation of cardiac muscle cell proliferation	Tgfbr3	IMP		Mouse	MGI:MGI:2663364\|PMID:12773577
Biological Process	GO:0008284	positive regulation of cell population proliferation	Tgfbr3	IMP		Mouse	PMID:25382630
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	Tgfbr3	IMP		Mouse	PMID:17823118
Biological Process	GO:0030511	positive regulation of transforming growth factor beta receptor signaling pathway	Tgfbr3	IMP		Mouse	PMID:25382630
Biological Process	GO:0030511	positive regulation of transforming growth factor beta receptor signaling pathway	Tgfbr3	IMP		Rat	PMID:8106553\|RGD:1579949
Biological Process	GO:0065003	protein-containing complex assembly	Tgfbr3	IDA		Rat	PMID:12385827\|RGD:1579945
Biological Process	GO:0043393	regulation of protein binding	Tgfbr3	IDA		Rat	PMID:12385827\|RGD:1579945
Biological Process	GO:0032354	response to follicle-stimulating hormone	TGFBR3	IDA		Human	PMID:14557487
Biological Process	GO:0001666	response to hypoxia	Tgfbr3	IEP		Rat	PMID:12183510\|RGD:727411
Biological Process	GO:0034699	response to luteinizing hormone	TGFBR3	IDA		Human	PMID:14557487
Biological Process	GO:0034695	response to prostaglandin E	TGFBR3	IDA		Human	PMID:14557487
Biological Process	GO:0060021	roof of mouth development	Tgfbr3	IMP		Mouse	PMID:25382630
Biological Process	GO:0062009	secondary palate development	Tgfbr3	IMP		Mouse	MGI:MGI:3699491\|PMID:17295310
Biological Process	GO:0061053	somite development	tgfbr3	IMP	ZFIN:ZDB-MRPHLNO-160902-3	Zfish	PMID:26174808
Biological Process	GO:0002040	sprouting angiogenesis	tgfbr3	IMP	ZFIN:ZDB-MRPHLNO-160902-3	Zfish	PMID:26174808
Biological Process	GO:0007181	transforming growth factor beta receptor complex assembly	Tgfbr3	IMP		Rat	PMID:8106553\|RGD:1579949
Biological Process	GO:0007179	transforming growth factor beta receptor signaling pathway	TGFBR3	IMP		Human	PMID:11157754
Biological Process	GO:0007179	transforming growth factor beta receptor signaling pathway	TGFBR3	IDA		Human	PMID:12958365
Biological Process	GO:0007179	transforming growth factor beta receptor signaling pathway	Tgfbr3	IGI	UniProtKB:P27090	Mouse	MGI:MGI:2663364\|PMID:12773577
Biological Process	GO:0007179	transforming growth factor beta receptor signaling pathway	Tgfbr3	IDA		Mouse	MGI:MGI:3699491\|PMID:17295310
Biological Process	GO:0007179	transforming growth factor beta receptor signaling pathway	Tgfbr3	IDA		Mouse	MGI:MGI:3807767\|PMID:11546783
Biological Process	GO:0007179	transforming growth factor beta receptor signaling pathway	Tgfbr3	IMP		Mouse	PMID:25382630
Biological Process	GO:0001570	vasculogenesis	Tgfbr3	IMP		Mouse	PMID:25382630
Biological Process	GO:0060979	vasculogenesis involved in coronary vascular morphogenesis	Tgfbr3	IMP		Mouse	MGI:MGI:3818140\|PMID:17704211
Biological Process	GO:0055010	ventricular cardiac muscle tissue morphogenesis	Tgfbr3	IMP		Mouse	MGI:MGI:2663364\|PMID:12773577
Biological Process	GO:0003223	ventricular compact myocardium morphogenesis	Tgfbr3	IMP		Mouse	MGI:MGI:3818140\|PMID:17704211
Biological Process	GO:0003223	ventricular compact myocardium morphogenesis	Tgfbr3	IMP		Mouse	MGI:MGI:2663364\|PMID:12773577
Biological Process	GO:0060412	ventricular septum morphogenesis	Tgfbr3	IMP		Mouse	MGI:MGI:3818140\|PMID:17704211

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 05/21/2024 MGI 6.23

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.