| GO term: | transforming growth factor beta-activated receptor activity |
| Synonym: | TGFbeta-activated receptor activity |
| Synonym: | TGFbetaR |
| Synonym: | TGF-beta receptor activity |
| Synonym: | TGFbeta receptor activity |
| Synonym: | transforming growth factor beta receptor activity |
| GO id: | GO:0005024 |
| Definition: | Combining with a transforming growth factor beta (TGFbeta) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate. |
| Comments | Note that this term represents an activity and not a gene product, and should only be used when the receptor binds the ligand TGFbeta. For binding to other growth factors, consider annotating to terms under 'transmembrane signaling receptor activity ; GO:0004888. |
| Number of paths to term: | 6 |
denotes an 'is-a' relationship
denotes a 'part-of' relationship
denotes a 'regulates' relationship
denotes a 'positively-regulates' relationship
denotes a 'negatively-regulates' relationship
molecular_functioncatalytic activitytransferase activitytransferase activity, transferring phosphorus-containing groupskinase activityprotein kinase activityprotein serine/threonine kinase activitytransmembrane receptor protein serine/threonine kinase activityactivin-activated receptor activity +transforming growth factor beta-activated receptor activity [GO:0005024] (14 genes, 28 annotations)transforming growth factor beta receptor activity, type Itransforming growth factor beta receptor activity, type IItransforming growth factor beta receptor activity, type IIImolecular_functioncatalytic activitytransferase activitytransferase activity, transferring phosphorus-containing groupskinase activityprotein kinase activitytransmembrane receptor protein kinase activitytransmembrane receptor protein serine/threonine kinase activityactivin-activated receptor activity +transforming growth factor beta-activated receptor activity [GO:0005024] (14 genes, 28 annotations)transforming growth factor beta receptor activity, type Itransforming growth factor beta receptor activity, type IItransforming growth factor beta receptor activity, type IIImolecular_functioncatalytic activitytransferase activitytransferase activity, transferring phosphorus-containing groupsphosphotransferase activity, alcohol group as acceptorprotein kinase activityprotein serine/threonine kinase activitytransmembrane receptor protein serine/threonine kinase activityactivin-activated receptor activity +transforming growth factor beta-activated receptor activity [GO:0005024] (14 genes, 28 annotations)transforming growth factor beta receptor activity, type Itransforming growth factor beta receptor activity, type IItransforming growth factor beta receptor activity, type IIImolecular_functioncatalytic activitytransferase activitytransferase activity, transferring phosphorus-containing groupsphosphotransferase activity, alcohol group as acceptorprotein kinase activitytransmembrane receptor protein kinase activitytransmembrane receptor protein serine/threonine kinase activityactivin-activated receptor activity +transforming growth factor beta-activated receptor activity [GO:0005024] (14 genes, 28 annotations)transforming growth factor beta receptor activity, type Itransforming growth factor beta receptor activity, type IItransforming growth factor beta receptor activity, type IIImolecular_functionmolecular transducer activitysignal transducer activitysignaling receptor activitytransmembrane signaling receptor activitytransmembrane receptor protein kinase activitytransmembrane receptor protein serine/threonine kinase activityactivin-activated receptor activity +transforming growth factor beta-activated receptor activity [GO:0005024] (14 genes, 28 annotations)transforming growth factor beta receptor activity, type Itransforming growth factor beta receptor activity, type IItransforming growth factor beta receptor activity, type IIImolecular_functionreceptor activitysignaling receptor activitytransmembrane signaling receptor activitytransmembrane receptor protein kinase activitytransmembrane receptor protein serine/threonine kinase activityactivin-activated receptor activity +transforming growth factor beta-activated receptor activity [GO:0005024] (14 genes, 28 annotations)transforming growth factor beta receptor activity, type Itransforming growth factor beta receptor activity, type IItransforming growth factor beta receptor activity, type IIIMouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc |
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last database update 05/08/2013 MGI 5.13 |
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