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Gene Ontology Browser
Term Detail
GO term:definitive hemopoiesis
Synonym: definitive haematopoiesis
Synonym: definitive haemopoiesis
Synonym: definitive hematopoiesis
GO id:GO:0060216
Definition:A second wave of blood cell production that, in vertebrates, generates long-term hemopoietic stem cells that continously provide erythroid, myeloid and lymphoid lineages throughout adulthood.
Number of paths to term: 14

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-abiological_process
                is-adevelopmental process
                        is-aanatomical structure development
                                is-aorgan development
                                        is-ahematopoietic or lymphoid organ development
                                                is-ahemopoiesis
                                                        is-adefinitive hemopoiesis [GO:0060216] (20 genes, 23 annotations)
                                                                part-ofdefinitive erythrocyte differentiation +
                                                        is-aembryonic hemopoiesis +
                                                        part-offibroblast growth factor receptor signaling pathway involved in hemopoiesis
                                                        part-ofhematopoietic progenitor cell differentiation +
                                                        part-ofhematopoietic stem cell differentiation +
                                                        part-ofhematopoietic stem cell proliferation +
                                                        part-ofleukocyte differentiation +
                                                        part-ofmyeloid cell differentiation +
                                                        is-apost-embryonic hemopoiesis +


Gene_Ontology
        is-abiological_process
                is-adevelopmental process
                        is-aanatomical structure development
                                is-asystem development
                                        is-aimmune system development
                                                part-ofhematopoietic or lymphoid organ development
                                                        is-ahemopoiesis
                                                                is-adefinitive hemopoiesis [GO:0060216] (20 genes, 23 annotations)
                                                                        part-ofdefinitive erythrocyte differentiation +
                                                                is-aembryonic hemopoiesis +
                                                                part-offibroblast growth factor receptor signaling pathway involved in hemopoiesis
                                                                part-ofhematopoietic progenitor cell differentiation +
                                                                part-ofhematopoietic stem cell differentiation +
                                                                part-ofhematopoietic stem cell proliferation +
                                                                part-ofleukocyte differentiation +
                                                                part-ofmyeloid cell differentiation +
                                                                is-apost-embryonic hemopoiesis +


Gene_Ontology
        is-abiological_process
                is-adevelopmental process
                        is-aanatomical structure development
                                is-asystem development
                                        part-oforgan development
                                                is-ahematopoietic or lymphoid organ development
                                                        is-ahemopoiesis
                                                                is-adefinitive hemopoiesis [GO:0060216] (20 genes, 23 annotations)
                                                                        part-ofdefinitive erythrocyte differentiation +
                                                                is-aembryonic hemopoiesis +
                                                                part-offibroblast growth factor receptor signaling pathway involved in hemopoiesis
                                                                part-ofhematopoietic progenitor cell differentiation +
                                                                part-ofhematopoietic stem cell differentiation +
                                                                part-ofhematopoietic stem cell proliferation +
                                                                part-ofleukocyte differentiation +
                                                                part-ofmyeloid cell differentiation +
                                                                is-apost-embryonic hemopoiesis +


Gene_Ontology
        is-abiological_process
                is-adevelopmental process
                        is-asingle-organism developmental process
                                is-ahematopoietic or lymphoid organ development
                                        is-ahemopoiesis
                                                is-adefinitive hemopoiesis [GO:0060216] (20 genes, 23 annotations)
                                                        part-ofdefinitive erythrocyte differentiation +
                                                is-aembryonic hemopoiesis +
                                                part-offibroblast growth factor receptor signaling pathway involved in hemopoiesis
                                                part-ofhematopoietic progenitor cell differentiation +
                                                part-ofhematopoietic stem cell differentiation +
                                                part-ofhematopoietic stem cell proliferation +
                                                part-ofleukocyte differentiation +
                                                part-ofmyeloid cell differentiation +
                                                is-apost-embryonic hemopoiesis +


Gene_Ontology
        is-abiological_process
                is-adevelopmental process
                        is-asingle-organism developmental process
                                is-amulticellular organismal development
                                        part-ofsystem development
                                                is-aimmune system development
                                                        part-ofhematopoietic or lymphoid organ development
                                                                is-ahemopoiesis
                                                                        is-adefinitive hemopoiesis [GO:0060216] (20 genes, 23 annotations)
                                                                                part-ofdefinitive erythrocyte differentiation +
                                                                        is-aembryonic hemopoiesis +
                                                                        part-offibroblast growth factor receptor signaling pathway involved in hemopoiesis
                                                                        part-ofhematopoietic progenitor cell differentiation +
                                                                        part-ofhematopoietic stem cell differentiation +
                                                                        part-ofhematopoietic stem cell proliferation +
                                                                        part-ofleukocyte differentiation +
                                                                        part-ofmyeloid cell differentiation +
                                                                        is-apost-embryonic hemopoiesis +


Gene_Ontology
        is-abiological_process
                is-adevelopmental process
                        is-asingle-organism developmental process
                                is-amulticellular organismal development
                                        part-ofsystem development
                                                part-oforgan development
                                                        is-ahematopoietic or lymphoid organ development
                                                                is-ahemopoiesis
                                                                        is-adefinitive hemopoiesis [GO:0060216] (20 genes, 23 annotations)
                                                                                part-ofdefinitive erythrocyte differentiation +
                                                                        is-aembryonic hemopoiesis +
                                                                        part-offibroblast growth factor receptor signaling pathway involved in hemopoiesis
                                                                        part-ofhematopoietic progenitor cell differentiation +
                                                                        part-ofhematopoietic stem cell differentiation +
                                                                        part-ofhematopoietic stem cell proliferation +
                                                                        part-ofleukocyte differentiation +
                                                                        part-ofmyeloid cell differentiation +
                                                                        is-apost-embryonic hemopoiesis +


Gene_Ontology
        is-abiological_process
                is-aimmune system process
                        is-aimmune system development
                                part-ofhematopoietic or lymphoid organ development
                                        is-ahemopoiesis
                                                is-adefinitive hemopoiesis [GO:0060216] (20 genes, 23 annotations)
                                                        part-ofdefinitive erythrocyte differentiation +
                                                is-aembryonic hemopoiesis +
                                                part-offibroblast growth factor receptor signaling pathway involved in hemopoiesis
                                                part-ofhematopoietic progenitor cell differentiation +
                                                part-ofhematopoietic stem cell differentiation +
                                                part-ofhematopoietic stem cell proliferation +
                                                part-ofleukocyte differentiation +
                                                part-ofmyeloid cell differentiation +
                                                is-apost-embryonic hemopoiesis +


Gene_Ontology
        is-abiological_process
                is-amulticellular organismal process
                        is-asingle-multicellular organism process
                                is-amulticellular organismal development
                                        part-ofsystem development
                                                is-aimmune system development
                                                        part-ofhematopoietic or lymphoid organ development
                                                                is-ahemopoiesis
                                                                        is-adefinitive hemopoiesis [GO:0060216] (20 genes, 23 annotations)
                                                                                part-ofdefinitive erythrocyte differentiation +
                                                                        is-aembryonic hemopoiesis +
                                                                        part-offibroblast growth factor receptor signaling pathway involved in hemopoiesis
                                                                        part-ofhematopoietic progenitor cell differentiation +
                                                                        part-ofhematopoietic stem cell differentiation +
                                                                        part-ofhematopoietic stem cell proliferation +
                                                                        part-ofleukocyte differentiation +
                                                                        part-ofmyeloid cell differentiation +
                                                                        is-apost-embryonic hemopoiesis +


Gene_Ontology
        is-abiological_process
                is-amulticellular organismal process
                        is-asingle-multicellular organism process
                                is-amulticellular organismal development
                                        part-ofsystem development
                                                part-oforgan development
                                                        is-ahematopoietic or lymphoid organ development
                                                                is-ahemopoiesis
                                                                        is-adefinitive hemopoiesis [GO:0060216] (20 genes, 23 annotations)
                                                                                part-ofdefinitive erythrocyte differentiation +
                                                                        is-aembryonic hemopoiesis +
                                                                        part-offibroblast growth factor receptor signaling pathway involved in hemopoiesis
                                                                        part-ofhematopoietic progenitor cell differentiation +
                                                                        part-ofhematopoietic stem cell differentiation +
                                                                        part-ofhematopoietic stem cell proliferation +
                                                                        part-ofleukocyte differentiation +
                                                                        part-ofmyeloid cell differentiation +
                                                                        is-apost-embryonic hemopoiesis +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-multicellular organism process
                                is-amulticellular organismal development
                                        part-ofsystem development
                                                is-aimmune system development
                                                        part-ofhematopoietic or lymphoid organ development
                                                                is-ahemopoiesis
                                                                        is-adefinitive hemopoiesis [GO:0060216] (20 genes, 23 annotations)
                                                                                part-ofdefinitive erythrocyte differentiation +
                                                                        is-aembryonic hemopoiesis +
                                                                        part-offibroblast growth factor receptor signaling pathway involved in hemopoiesis
                                                                        part-ofhematopoietic progenitor cell differentiation +
                                                                        part-ofhematopoietic stem cell differentiation +
                                                                        part-ofhematopoietic stem cell proliferation +
                                                                        part-ofleukocyte differentiation +
                                                                        part-ofmyeloid cell differentiation +
                                                                        is-apost-embryonic hemopoiesis +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-multicellular organism process
                                is-amulticellular organismal development
                                        part-ofsystem development
                                                part-oforgan development
                                                        is-ahematopoietic or lymphoid organ development
                                                                is-ahemopoiesis
                                                                        is-adefinitive hemopoiesis [GO:0060216] (20 genes, 23 annotations)
                                                                                part-ofdefinitive erythrocyte differentiation +
                                                                        is-aembryonic hemopoiesis +
                                                                        part-offibroblast growth factor receptor signaling pathway involved in hemopoiesis
                                                                        part-ofhematopoietic progenitor cell differentiation +
                                                                        part-ofhematopoietic stem cell differentiation +
                                                                        part-ofhematopoietic stem cell proliferation +
                                                                        part-ofleukocyte differentiation +
                                                                        part-ofmyeloid cell differentiation +
                                                                        is-apost-embryonic hemopoiesis +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism developmental process
                                is-ahematopoietic or lymphoid organ development
                                        is-ahemopoiesis
                                                is-adefinitive hemopoiesis [GO:0060216] (20 genes, 23 annotations)
                                                        part-ofdefinitive erythrocyte differentiation +
                                                is-aembryonic hemopoiesis +
                                                part-offibroblast growth factor receptor signaling pathway involved in hemopoiesis
                                                part-ofhematopoietic progenitor cell differentiation +
                                                part-ofhematopoietic stem cell differentiation +
                                                part-ofhematopoietic stem cell proliferation +
                                                part-ofleukocyte differentiation +
                                                part-ofmyeloid cell differentiation +
                                                is-apost-embryonic hemopoiesis +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism developmental process
                                is-amulticellular organismal development
                                        part-ofsystem development
                                                is-aimmune system development
                                                        part-ofhematopoietic or lymphoid organ development
                                                                is-ahemopoiesis
                                                                        is-adefinitive hemopoiesis [GO:0060216] (20 genes, 23 annotations)
                                                                                part-ofdefinitive erythrocyte differentiation +
                                                                        is-aembryonic hemopoiesis +
                                                                        part-offibroblast growth factor receptor signaling pathway involved in hemopoiesis
                                                                        part-ofhematopoietic progenitor cell differentiation +
                                                                        part-ofhematopoietic stem cell differentiation +
                                                                        part-ofhematopoietic stem cell proliferation +
                                                                        part-ofleukocyte differentiation +
                                                                        part-ofmyeloid cell differentiation +
                                                                        is-apost-embryonic hemopoiesis +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism developmental process
                                is-amulticellular organismal development
                                        part-ofsystem development
                                                part-oforgan development
                                                        is-ahematopoietic or lymphoid organ development
                                                                is-ahemopoiesis
                                                                        is-adefinitive hemopoiesis [GO:0060216] (20 genes, 23 annotations)
                                                                                part-ofdefinitive erythrocyte differentiation +
                                                                        is-aembryonic hemopoiesis +
                                                                        part-offibroblast growth factor receptor signaling pathway involved in hemopoiesis
                                                                        part-ofhematopoietic progenitor cell differentiation +
                                                                        part-ofhematopoietic stem cell differentiation +
                                                                        part-ofhematopoietic stem cell proliferation +
                                                                        part-ofleukocyte differentiation +
                                                                        part-ofmyeloid cell differentiation +
                                                                        is-apost-embryonic hemopoiesis +


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last database update
11/18/2014
MGI 5.20
The Jackson Laboratory