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Gene Ontology Browser
Term Detail
GO term:intracellular signal transduction
Synonym: intracellular protein kinase cascade
Synonym: intracellular signaling cascade
Synonym: intracellular signaling chain
Synonym: intracellular signaling pathway
Synonym: intracellular signal transduction pathway
Synonym: protein kinase cascade
Synonym: signal transduction via intracellular signaling cascade
Synonym: signal transmission via intracellular cascade
GO id:GO:0035556
Definition:The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell.
Number of paths to term: 9

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-asignal transduction
                                                is-aapoptotic signaling pathway +
                                                is-abile acid signaling pathway +
                                                is-acarbohydrate mediated signaling +
                                                is-acell surface receptor signaling pathway +
                                                is-achloroplast-nucleus signaling pathway
                                                is-adefense response signaling pathway, resistance gene-dependent
                                                is-adefense response signaling pathway, resistance gene-independent
                                                is-aER-nucleus signaling pathway +
                                                is-ahormone-mediated signaling pathway +
                                                is-ahydrogen peroxide mediated signaling pathway +
                                                is-ahypoxia-inducible factor-1alpha signaling pathway +
                                                is-aimmune response-regulating signaling pathway +
                                                is-aintracellular receptor signaling pathway +
                                                is-aintracellular signal transduction [GO:0035556] (1993 genes, 3833 annotations)
                                                        is-acytoplasmic pattern recognition receptor signaling pathway +
                                                        is-aendosomal signal transduction
                                                        is-ahippo signaling +
                                                        is-aI-kappaB kinase/NF-kappaB signaling +
                                                        is-ainositol lipid-mediated signaling +
                                                        is-aintrinsic apoptotic signaling pathway +
                                                        is-aJAK-STAT cascade +
                                                        is-aMAPK cascade +
                                                        is-aMAPK import into nucleus involved in innate immune response
                                                        negatively-regulatesnegative regulation of intracellular signal transduction +
                                                        is-aNIK/NF-kappaB signaling +
                                                        is-aPKR signal transduction
                                                        positively-regulatespositive regulation of intracellular signal transduction +
                                                        is-aprotein kinase A signaling +
                                                        is-aprotein kinase B signaling +
                                                        is-aprotein kinase C signaling +
                                                        regulatesregulation of intracellular signal transduction +
                                                        is-asecond-messenger-mediated signaling +
                                                        is-asignal transduction by p53 class mediator +
                                                        is-asignal transduction downstream of smoothened +
                                                        is-asignal transduction in response to DNA damage +
                                                        is-asignal transduction involved in cell cycle checkpoint +
                                                        is-asmall GTPase mediated signal transduction +
                                                        is-astress-activated protein kinase signaling cascade +
                                                        is-aTOR signaling +
                                                        is-aTRAF-mediated signal transduction
                                                is-alipoprotein particle mediated signaling +
                                                is-amitochondria-nucleus signaling pathway
                                                is-anecroptotic signaling pathway
                                                negatively-regulatesnegative regulation of signal transduction +
                                                is-aneuronal signal transduction +
                                                is-aosmosensory signaling pathway +
                                                is-aphosphorelay signal transduction system +
                                                is-aphototransduction +
                                                positively-regulatespositive regulation of signal transduction +
                                                is-ared or far-red light signaling pathway +
                                                is-aregulation of blood pressure by chemoreceptor signaling pathway +
                                                is-aregulation of floral organ abscission by signal transduction +
                                                regulatesregulation of signal transduction +
                                                is-asalicylic acid mediated signaling pathway +
                                                is-asignal transduction by conformational transition
                                                is-asignal transduction by phosphorylation +
                                                is-asignal transduction in absence of ligand +
                                                is-asignal transduction involved in conjugation with cellular fusion +
                                                is-asignal transduction involved in Dma1-dependent checkpoint
                                                is-asignal transduction involved in filamentous growth
                                                is-asignal transduction involved in regulation of gene expression
                                                is-aSMAD protein signal transduction
                                                is-asphingolipid mediated signaling pathway +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-acellular response to stimulus
                                is-asignal transduction
                                        is-aapoptotic signaling pathway +
                                        is-abile acid signaling pathway +
                                        is-acarbohydrate mediated signaling +
                                        is-acell surface receptor signaling pathway +
                                        is-achloroplast-nucleus signaling pathway
                                        is-adefense response signaling pathway, resistance gene-dependent
                                        is-adefense response signaling pathway, resistance gene-independent
                                        is-aER-nucleus signaling pathway +
                                        is-ahormone-mediated signaling pathway +
                                        is-ahydrogen peroxide mediated signaling pathway +
                                        is-ahypoxia-inducible factor-1alpha signaling pathway +
                                        is-aimmune response-regulating signaling pathway +
                                        is-aintracellular receptor signaling pathway +
                                        is-aintracellular signal transduction [GO:0035556] (1993 genes, 3833 annotations)
                                                is-acytoplasmic pattern recognition receptor signaling pathway +
                                                is-aendosomal signal transduction
                                                is-ahippo signaling +
                                                is-aI-kappaB kinase/NF-kappaB signaling +
                                                is-ainositol lipid-mediated signaling +
                                                is-aintrinsic apoptotic signaling pathway +
                                                is-aJAK-STAT cascade +
                                                is-aMAPK cascade +
                                                is-aMAPK import into nucleus involved in innate immune response
                                                negatively-regulatesnegative regulation of intracellular signal transduction +
                                                is-aNIK/NF-kappaB signaling +
                                                is-aPKR signal transduction
                                                positively-regulatespositive regulation of intracellular signal transduction +
                                                is-aprotein kinase A signaling +
                                                is-aprotein kinase B signaling +
                                                is-aprotein kinase C signaling +
                                                regulatesregulation of intracellular signal transduction +
                                                is-asecond-messenger-mediated signaling +
                                                is-asignal transduction by p53 class mediator +
                                                is-asignal transduction downstream of smoothened +
                                                is-asignal transduction in response to DNA damage +
                                                is-asignal transduction involved in cell cycle checkpoint +
                                                is-asmall GTPase mediated signal transduction +
                                                is-astress-activated protein kinase signaling cascade +
                                                is-aTOR signaling +
                                                is-aTRAF-mediated signal transduction
                                        is-alipoprotein particle mediated signaling +
                                        is-amitochondria-nucleus signaling pathway
                                        is-anecroptotic signaling pathway
                                        negatively-regulatesnegative regulation of signal transduction +
                                        is-aneuronal signal transduction +
                                        is-aosmosensory signaling pathway +
                                        is-aphosphorelay signal transduction system +
                                        is-aphototransduction +
                                        positively-regulatespositive regulation of signal transduction +
                                        is-ared or far-red light signaling pathway +
                                        is-aregulation of blood pressure by chemoreceptor signaling pathway +
                                        is-aregulation of floral organ abscission by signal transduction +
                                        regulatesregulation of signal transduction +
                                        is-asalicylic acid mediated signaling pathway +
                                        is-asignal transduction by conformational transition
                                        is-asignal transduction by phosphorylation +
                                        is-asignal transduction in absence of ligand +
                                        is-asignal transduction involved in conjugation with cellular fusion +
                                        is-asignal transduction involved in Dma1-dependent checkpoint
                                        is-asignal transduction involved in filamentous growth
                                        is-asignal transduction involved in regulation of gene expression
                                        is-aSMAD protein signal transduction
                                        is-asphingolipid mediated signaling pathway +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        regulatesregulation of cellular process
                                is-asignal transduction
                                        is-aapoptotic signaling pathway +
                                        is-abile acid signaling pathway +
                                        is-acarbohydrate mediated signaling +
                                        is-acell surface receptor signaling pathway +
                                        is-achloroplast-nucleus signaling pathway
                                        is-adefense response signaling pathway, resistance gene-dependent
                                        is-adefense response signaling pathway, resistance gene-independent
                                        is-aER-nucleus signaling pathway +
                                        is-ahormone-mediated signaling pathway +
                                        is-ahydrogen peroxide mediated signaling pathway +
                                        is-ahypoxia-inducible factor-1alpha signaling pathway +
                                        is-aimmune response-regulating signaling pathway +
                                        is-aintracellular receptor signaling pathway +
                                        is-aintracellular signal transduction [GO:0035556] (1993 genes, 3833 annotations)
                                                is-acytoplasmic pattern recognition receptor signaling pathway +
                                                is-aendosomal signal transduction
                                                is-ahippo signaling +
                                                is-aI-kappaB kinase/NF-kappaB signaling +
                                                is-ainositol lipid-mediated signaling +
                                                is-aintrinsic apoptotic signaling pathway +
                                                is-aJAK-STAT cascade +
                                                is-aMAPK cascade +
                                                is-aMAPK import into nucleus involved in innate immune response
                                                negatively-regulatesnegative regulation of intracellular signal transduction +
                                                is-aNIK/NF-kappaB signaling +
                                                is-aPKR signal transduction
                                                positively-regulatespositive regulation of intracellular signal transduction +
                                                is-aprotein kinase A signaling +
                                                is-aprotein kinase B signaling +
                                                is-aprotein kinase C signaling +
                                                regulatesregulation of intracellular signal transduction +
                                                is-asecond-messenger-mediated signaling +
                                                is-asignal transduction by p53 class mediator +
                                                is-asignal transduction downstream of smoothened +
                                                is-asignal transduction in response to DNA damage +
                                                is-asignal transduction involved in cell cycle checkpoint +
                                                is-asmall GTPase mediated signal transduction +
                                                is-astress-activated protein kinase signaling cascade +
                                                is-aTOR signaling +
                                                is-aTRAF-mediated signal transduction
                                        is-alipoprotein particle mediated signaling +
                                        is-amitochondria-nucleus signaling pathway
                                        is-anecroptotic signaling pathway
                                        negatively-regulatesnegative regulation of signal transduction +
                                        is-aneuronal signal transduction +
                                        is-aosmosensory signaling pathway +
                                        is-aphosphorelay signal transduction system +
                                        is-aphototransduction +
                                        positively-regulatespositive regulation of signal transduction +
                                        is-ared or far-red light signaling pathway +
                                        is-aregulation of blood pressure by chemoreceptor signaling pathway +
                                        is-aregulation of floral organ abscission by signal transduction +
                                        regulatesregulation of signal transduction +
                                        is-asalicylic acid mediated signaling pathway +
                                        is-asignal transduction by conformational transition
                                        is-asignal transduction by phosphorylation +
                                        is-asignal transduction in absence of ligand +
                                        is-asignal transduction involved in conjugation with cellular fusion +
                                        is-asignal transduction involved in Dma1-dependent checkpoint
                                        is-asignal transduction involved in filamentous growth
                                        is-asignal transduction involved in regulation of gene expression
                                        is-aSMAD protein signal transduction
                                        is-asphingolipid mediated signaling pathway +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acell communication
                                        part-ofsignal transduction
                                                is-aapoptotic signaling pathway +
                                                is-abile acid signaling pathway +
                                                is-acarbohydrate mediated signaling +
                                                is-acell surface receptor signaling pathway +
                                                is-achloroplast-nucleus signaling pathway
                                                is-adefense response signaling pathway, resistance gene-dependent
                                                is-adefense response signaling pathway, resistance gene-independent
                                                is-aER-nucleus signaling pathway +
                                                is-ahormone-mediated signaling pathway +
                                                is-ahydrogen peroxide mediated signaling pathway +
                                                is-ahypoxia-inducible factor-1alpha signaling pathway +
                                                is-aimmune response-regulating signaling pathway +
                                                is-aintracellular receptor signaling pathway +
                                                is-aintracellular signal transduction [GO:0035556] (1993 genes, 3833 annotations)
                                                        is-acytoplasmic pattern recognition receptor signaling pathway +
                                                        is-aendosomal signal transduction
                                                        is-ahippo signaling +
                                                        is-aI-kappaB kinase/NF-kappaB signaling +
                                                        is-ainositol lipid-mediated signaling +
                                                        is-aintrinsic apoptotic signaling pathway +
                                                        is-aJAK-STAT cascade +
                                                        is-aMAPK cascade +
                                                        is-aMAPK import into nucleus involved in innate immune response
                                                        negatively-regulatesnegative regulation of intracellular signal transduction +
                                                        is-aNIK/NF-kappaB signaling +
                                                        is-aPKR signal transduction
                                                        positively-regulatespositive regulation of intracellular signal transduction +
                                                        is-aprotein kinase A signaling +
                                                        is-aprotein kinase B signaling +
                                                        is-aprotein kinase C signaling +
                                                        regulatesregulation of intracellular signal transduction +
                                                        is-asecond-messenger-mediated signaling +
                                                        is-asignal transduction by p53 class mediator +
                                                        is-asignal transduction downstream of smoothened +
                                                        is-asignal transduction in response to DNA damage +
                                                        is-asignal transduction involved in cell cycle checkpoint +
                                                        is-asmall GTPase mediated signal transduction +
                                                        is-astress-activated protein kinase signaling cascade +
                                                        is-aTOR signaling +
                                                        is-aTRAF-mediated signal transduction
                                                is-alipoprotein particle mediated signaling +
                                                is-amitochondria-nucleus signaling pathway
                                                is-anecroptotic signaling pathway
                                                negatively-regulatesnegative regulation of signal transduction +
                                                is-aneuronal signal transduction +
                                                is-aosmosensory signaling pathway +
                                                is-aphosphorelay signal transduction system +
                                                is-aphototransduction +
                                                positively-regulatespositive regulation of signal transduction +
                                                is-ared or far-red light signaling pathway +
                                                is-aregulation of blood pressure by chemoreceptor signaling pathway +
                                                is-aregulation of floral organ abscission by signal transduction +
                                                regulatesregulation of signal transduction +
                                                is-asalicylic acid mediated signaling pathway +
                                                is-asignal transduction by conformational transition
                                                is-asignal transduction by phosphorylation +
                                                is-asignal transduction in absence of ligand +
                                                is-asignal transduction involved in conjugation with cellular fusion +
                                                is-asignal transduction involved in Dma1-dependent checkpoint
                                                is-asignal transduction involved in filamentous growth
                                                is-asignal transduction involved in regulation of gene expression
                                                is-aSMAD protein signal transduction
                                                is-asphingolipid mediated signaling pathway +


Gene_Ontology
        is-abiological_process
                regulatesregulation of biological process
                        is-aregulation of cellular process
                                is-asignal transduction
                                        is-aapoptotic signaling pathway +
                                        is-abile acid signaling pathway +
                                        is-acarbohydrate mediated signaling +
                                        is-acell surface receptor signaling pathway +
                                        is-achloroplast-nucleus signaling pathway
                                        is-adefense response signaling pathway, resistance gene-dependent
                                        is-adefense response signaling pathway, resistance gene-independent
                                        is-aER-nucleus signaling pathway +
                                        is-ahormone-mediated signaling pathway +
                                        is-ahydrogen peroxide mediated signaling pathway +
                                        is-ahypoxia-inducible factor-1alpha signaling pathway +
                                        is-aimmune response-regulating signaling pathway +
                                        is-aintracellular receptor signaling pathway +
                                        is-aintracellular signal transduction [GO:0035556] (1993 genes, 3833 annotations)
                                                is-acytoplasmic pattern recognition receptor signaling pathway +
                                                is-aendosomal signal transduction
                                                is-ahippo signaling +
                                                is-aI-kappaB kinase/NF-kappaB signaling +
                                                is-ainositol lipid-mediated signaling +
                                                is-aintrinsic apoptotic signaling pathway +
                                                is-aJAK-STAT cascade +
                                                is-aMAPK cascade +
                                                is-aMAPK import into nucleus involved in innate immune response
                                                negatively-regulatesnegative regulation of intracellular signal transduction +
                                                is-aNIK/NF-kappaB signaling +
                                                is-aPKR signal transduction
                                                positively-regulatespositive regulation of intracellular signal transduction +
                                                is-aprotein kinase A signaling +
                                                is-aprotein kinase B signaling +
                                                is-aprotein kinase C signaling +
                                                regulatesregulation of intracellular signal transduction +
                                                is-asecond-messenger-mediated signaling +
                                                is-asignal transduction by p53 class mediator +
                                                is-asignal transduction downstream of smoothened +
                                                is-asignal transduction in response to DNA damage +
                                                is-asignal transduction involved in cell cycle checkpoint +
                                                is-asmall GTPase mediated signal transduction +
                                                is-astress-activated protein kinase signaling cascade +
                                                is-aTOR signaling +
                                                is-aTRAF-mediated signal transduction
                                        is-alipoprotein particle mediated signaling +
                                        is-amitochondria-nucleus signaling pathway
                                        is-anecroptotic signaling pathway
                                        negatively-regulatesnegative regulation of signal transduction +
                                        is-aneuronal signal transduction +
                                        is-aosmosensory signaling pathway +
                                        is-aphosphorelay signal transduction system +
                                        is-aphototransduction +
                                        positively-regulatespositive regulation of signal transduction +
                                        is-ared or far-red light signaling pathway +
                                        is-aregulation of blood pressure by chemoreceptor signaling pathway +
                                        is-aregulation of floral organ abscission by signal transduction +
                                        regulatesregulation of signal transduction +
                                        is-asalicylic acid mediated signaling pathway +
                                        is-asignal transduction by conformational transition
                                        is-asignal transduction by phosphorylation +
                                        is-asignal transduction in absence of ligand +
                                        is-asignal transduction involved in conjugation with cellular fusion +
                                        is-asignal transduction involved in Dma1-dependent checkpoint
                                        is-asignal transduction involved in filamentous growth
                                        is-asignal transduction involved in regulation of gene expression
                                        is-aSMAD protein signal transduction
                                        is-asphingolipid mediated signaling pathway +


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-acellular response to stimulus
                                is-asignal transduction
                                        is-aapoptotic signaling pathway +
                                        is-abile acid signaling pathway +
                                        is-acarbohydrate mediated signaling +
                                        is-acell surface receptor signaling pathway +
                                        is-achloroplast-nucleus signaling pathway
                                        is-adefense response signaling pathway, resistance gene-dependent
                                        is-adefense response signaling pathway, resistance gene-independent
                                        is-aER-nucleus signaling pathway +
                                        is-ahormone-mediated signaling pathway +
                                        is-ahydrogen peroxide mediated signaling pathway +
                                        is-ahypoxia-inducible factor-1alpha signaling pathway +
                                        is-aimmune response-regulating signaling pathway +
                                        is-aintracellular receptor signaling pathway +
                                        is-aintracellular signal transduction [GO:0035556] (1993 genes, 3833 annotations)
                                                is-acytoplasmic pattern recognition receptor signaling pathway +
                                                is-aendosomal signal transduction
                                                is-ahippo signaling +
                                                is-aI-kappaB kinase/NF-kappaB signaling +
                                                is-ainositol lipid-mediated signaling +
                                                is-aintrinsic apoptotic signaling pathway +
                                                is-aJAK-STAT cascade +
                                                is-aMAPK cascade +
                                                is-aMAPK import into nucleus involved in innate immune response
                                                negatively-regulatesnegative regulation of intracellular signal transduction +
                                                is-aNIK/NF-kappaB signaling +
                                                is-aPKR signal transduction
                                                positively-regulatespositive regulation of intracellular signal transduction +
                                                is-aprotein kinase A signaling +
                                                is-aprotein kinase B signaling +
                                                is-aprotein kinase C signaling +
                                                regulatesregulation of intracellular signal transduction +
                                                is-asecond-messenger-mediated signaling +
                                                is-asignal transduction by p53 class mediator +
                                                is-asignal transduction downstream of smoothened +
                                                is-asignal transduction in response to DNA damage +
                                                is-asignal transduction involved in cell cycle checkpoint +
                                                is-asmall GTPase mediated signal transduction +
                                                is-astress-activated protein kinase signaling cascade +
                                                is-aTOR signaling +
                                                is-aTRAF-mediated signal transduction
                                        is-alipoprotein particle mediated signaling +
                                        is-amitochondria-nucleus signaling pathway
                                        is-anecroptotic signaling pathway
                                        negatively-regulatesnegative regulation of signal transduction +
                                        is-aneuronal signal transduction +
                                        is-aosmosensory signaling pathway +
                                        is-aphosphorelay signal transduction system +
                                        is-aphototransduction +
                                        positively-regulatespositive regulation of signal transduction +
                                        is-ared or far-red light signaling pathway +
                                        is-aregulation of blood pressure by chemoreceptor signaling pathway +
                                        is-aregulation of floral organ abscission by signal transduction +
                                        regulatesregulation of signal transduction +
                                        is-asalicylic acid mediated signaling pathway +
                                        is-asignal transduction by conformational transition
                                        is-asignal transduction by phosphorylation +
                                        is-asignal transduction in absence of ligand +
                                        is-asignal transduction involved in conjugation with cellular fusion +
                                        is-asignal transduction involved in Dma1-dependent checkpoint
                                        is-asignal transduction involved in filamentous growth
                                        is-asignal transduction involved in regulation of gene expression
                                        is-aSMAD protein signal transduction
                                        is-asphingolipid mediated signaling pathway +


Gene_Ontology
        is-abiological_process
                is-asignaling
                        is-asingle organism signaling
                                part-ofsignal transduction
                                        is-aapoptotic signaling pathway +
                                        is-abile acid signaling pathway +
                                        is-acarbohydrate mediated signaling +
                                        is-acell surface receptor signaling pathway +
                                        is-achloroplast-nucleus signaling pathway
                                        is-adefense response signaling pathway, resistance gene-dependent
                                        is-adefense response signaling pathway, resistance gene-independent
                                        is-aER-nucleus signaling pathway +
                                        is-ahormone-mediated signaling pathway +
                                        is-ahydrogen peroxide mediated signaling pathway +
                                        is-ahypoxia-inducible factor-1alpha signaling pathway +
                                        is-aimmune response-regulating signaling pathway +
                                        is-aintracellular receptor signaling pathway +
                                        is-aintracellular signal transduction [GO:0035556] (1993 genes, 3833 annotations)
                                                is-acytoplasmic pattern recognition receptor signaling pathway +
                                                is-aendosomal signal transduction
                                                is-ahippo signaling +
                                                is-aI-kappaB kinase/NF-kappaB signaling +
                                                is-ainositol lipid-mediated signaling +
                                                is-aintrinsic apoptotic signaling pathway +
                                                is-aJAK-STAT cascade +
                                                is-aMAPK cascade +
                                                is-aMAPK import into nucleus involved in innate immune response
                                                negatively-regulatesnegative regulation of intracellular signal transduction +
                                                is-aNIK/NF-kappaB signaling +
                                                is-aPKR signal transduction
                                                positively-regulatespositive regulation of intracellular signal transduction +
                                                is-aprotein kinase A signaling +
                                                is-aprotein kinase B signaling +
                                                is-aprotein kinase C signaling +
                                                regulatesregulation of intracellular signal transduction +
                                                is-asecond-messenger-mediated signaling +
                                                is-asignal transduction by p53 class mediator +
                                                is-asignal transduction downstream of smoothened +
                                                is-asignal transduction in response to DNA damage +
                                                is-asignal transduction involved in cell cycle checkpoint +
                                                is-asmall GTPase mediated signal transduction +
                                                is-astress-activated protein kinase signaling cascade +
                                                is-aTOR signaling +
                                                is-aTRAF-mediated signal transduction
                                        is-alipoprotein particle mediated signaling +
                                        is-amitochondria-nucleus signaling pathway
                                        is-anecroptotic signaling pathway
                                        negatively-regulatesnegative regulation of signal transduction +
                                        is-aneuronal signal transduction +
                                        is-aosmosensory signaling pathway +
                                        is-aphosphorelay signal transduction system +
                                        is-aphototransduction +
                                        positively-regulatespositive regulation of signal transduction +
                                        is-ared or far-red light signaling pathway +
                                        is-aregulation of blood pressure by chemoreceptor signaling pathway +
                                        is-aregulation of floral organ abscission by signal transduction +
                                        regulatesregulation of signal transduction +
                                        is-asalicylic acid mediated signaling pathway +
                                        is-asignal transduction by conformational transition
                                        is-asignal transduction by phosphorylation +
                                        is-asignal transduction in absence of ligand +
                                        is-asignal transduction involved in conjugation with cellular fusion +
                                        is-asignal transduction involved in Dma1-dependent checkpoint
                                        is-asignal transduction involved in filamentous growth
                                        is-asignal transduction involved in regulation of gene expression
                                        is-aSMAD protein signal transduction
                                        is-asphingolipid mediated signaling pathway +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle organism signaling
                                part-ofsignal transduction
                                        is-aapoptotic signaling pathway +
                                        is-abile acid signaling pathway +
                                        is-acarbohydrate mediated signaling +
                                        is-acell surface receptor signaling pathway +
                                        is-achloroplast-nucleus signaling pathway
                                        is-adefense response signaling pathway, resistance gene-dependent
                                        is-adefense response signaling pathway, resistance gene-independent
                                        is-aER-nucleus signaling pathway +
                                        is-ahormone-mediated signaling pathway +
                                        is-ahydrogen peroxide mediated signaling pathway +
                                        is-ahypoxia-inducible factor-1alpha signaling pathway +
                                        is-aimmune response-regulating signaling pathway +
                                        is-aintracellular receptor signaling pathway +
                                        is-aintracellular signal transduction [GO:0035556] (1993 genes, 3833 annotations)
                                                is-acytoplasmic pattern recognition receptor signaling pathway +
                                                is-aendosomal signal transduction
                                                is-ahippo signaling +
                                                is-aI-kappaB kinase/NF-kappaB signaling +
                                                is-ainositol lipid-mediated signaling +
                                                is-aintrinsic apoptotic signaling pathway +
                                                is-aJAK-STAT cascade +
                                                is-aMAPK cascade +
                                                is-aMAPK import into nucleus involved in innate immune response
                                                negatively-regulatesnegative regulation of intracellular signal transduction +
                                                is-aNIK/NF-kappaB signaling +
                                                is-aPKR signal transduction
                                                positively-regulatespositive regulation of intracellular signal transduction +
                                                is-aprotein kinase A signaling +
                                                is-aprotein kinase B signaling +
                                                is-aprotein kinase C signaling +
                                                regulatesregulation of intracellular signal transduction +
                                                is-asecond-messenger-mediated signaling +
                                                is-asignal transduction by p53 class mediator +
                                                is-asignal transduction downstream of smoothened +
                                                is-asignal transduction in response to DNA damage +
                                                is-asignal transduction involved in cell cycle checkpoint +
                                                is-asmall GTPase mediated signal transduction +
                                                is-astress-activated protein kinase signaling cascade +
                                                is-aTOR signaling +
                                                is-aTRAF-mediated signal transduction
                                        is-alipoprotein particle mediated signaling +
                                        is-amitochondria-nucleus signaling pathway
                                        is-anecroptotic signaling pathway
                                        negatively-regulatesnegative regulation of signal transduction +
                                        is-aneuronal signal transduction +
                                        is-aosmosensory signaling pathway +
                                        is-aphosphorelay signal transduction system +
                                        is-aphototransduction +
                                        positively-regulatespositive regulation of signal transduction +
                                        is-ared or far-red light signaling pathway +
                                        is-aregulation of blood pressure by chemoreceptor signaling pathway +
                                        is-aregulation of floral organ abscission by signal transduction +
                                        regulatesregulation of signal transduction +
                                        is-asalicylic acid mediated signaling pathway +
                                        is-asignal transduction by conformational transition
                                        is-asignal transduction by phosphorylation +
                                        is-asignal transduction in absence of ligand +
                                        is-asignal transduction involved in conjugation with cellular fusion +
                                        is-asignal transduction involved in Dma1-dependent checkpoint
                                        is-asignal transduction involved in filamentous growth
                                        is-asignal transduction involved in regulation of gene expression
                                        is-aSMAD protein signal transduction
                                        is-asphingolipid mediated signaling pathway +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-acell communication
                                        part-ofsignal transduction
                                                is-aapoptotic signaling pathway +
                                                is-abile acid signaling pathway +
                                                is-acarbohydrate mediated signaling +
                                                is-acell surface receptor signaling pathway +
                                                is-achloroplast-nucleus signaling pathway
                                                is-adefense response signaling pathway, resistance gene-dependent
                                                is-adefense response signaling pathway, resistance gene-independent
                                                is-aER-nucleus signaling pathway +
                                                is-ahormone-mediated signaling pathway +
                                                is-ahydrogen peroxide mediated signaling pathway +
                                                is-ahypoxia-inducible factor-1alpha signaling pathway +
                                                is-aimmune response-regulating signaling pathway +
                                                is-aintracellular receptor signaling pathway +
                                                is-aintracellular signal transduction [GO:0035556] (1993 genes, 3833 annotations)
                                                        is-acytoplasmic pattern recognition receptor signaling pathway +
                                                        is-aendosomal signal transduction
                                                        is-ahippo signaling +
                                                        is-aI-kappaB kinase/NF-kappaB signaling +
                                                        is-ainositol lipid-mediated signaling +
                                                        is-aintrinsic apoptotic signaling pathway +
                                                        is-aJAK-STAT cascade +
                                                        is-aMAPK cascade +
                                                        is-aMAPK import into nucleus involved in innate immune response
                                                        negatively-regulatesnegative regulation of intracellular signal transduction +
                                                        is-aNIK/NF-kappaB signaling +
                                                        is-aPKR signal transduction
                                                        positively-regulatespositive regulation of intracellular signal transduction +
                                                        is-aprotein kinase A signaling +
                                                        is-aprotein kinase B signaling +
                                                        is-aprotein kinase C signaling +
                                                        regulatesregulation of intracellular signal transduction +
                                                        is-asecond-messenger-mediated signaling +
                                                        is-asignal transduction by p53 class mediator +
                                                        is-asignal transduction downstream of smoothened +
                                                        is-asignal transduction in response to DNA damage +
                                                        is-asignal transduction involved in cell cycle checkpoint +
                                                        is-asmall GTPase mediated signal transduction +
                                                        is-astress-activated protein kinase signaling cascade +
                                                        is-aTOR signaling +
                                                        is-aTRAF-mediated signal transduction
                                                is-alipoprotein particle mediated signaling +
                                                is-amitochondria-nucleus signaling pathway
                                                is-anecroptotic signaling pathway
                                                negatively-regulatesnegative regulation of signal transduction +
                                                is-aneuronal signal transduction +
                                                is-aosmosensory signaling pathway +
                                                is-aphosphorelay signal transduction system +
                                                is-aphototransduction +
                                                positively-regulatespositive regulation of signal transduction +
                                                is-ared or far-red light signaling pathway +
                                                is-aregulation of blood pressure by chemoreceptor signaling pathway +
                                                is-aregulation of floral organ abscission by signal transduction +
                                                regulatesregulation of signal transduction +
                                                is-asalicylic acid mediated signaling pathway +
                                                is-asignal transduction by conformational transition
                                                is-asignal transduction by phosphorylation +
                                                is-asignal transduction in absence of ligand +
                                                is-asignal transduction involved in conjugation with cellular fusion +
                                                is-asignal transduction involved in Dma1-dependent checkpoint
                                                is-asignal transduction involved in filamentous growth
                                                is-asignal transduction involved in regulation of gene expression
                                                is-aSMAD protein signal transduction
                                                is-asphingolipid mediated signaling pathway +


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory