Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Lyn

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes LYN
- Mouse genes Lyn
- Rat genes Lyn
- Zfish genes lyn
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Lyn

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019899	enzyme binding	Lyn	IPI	RGD:620224	Rat	PMID:14529711\|RGD:2303716
Molecular Function	GO:0019899	enzyme binding	Lyn	IPI	RGD:620521	Rat	PMID:18579528\|RGD:2303650
Molecular Function	GO:0019899	enzyme binding	Lyn	IPI	RGD:3796	Rat	PMID:8190127\|RGD:2303717
Molecular Function	GO:0019899	enzyme binding	Lyn	IPI	RGD:71096	Rat	PMID:8757630\|RGD:2303645
Molecular Function	GO:0019899	enzyme binding	Lyn	IPI	RGD:67383	Rat	PMID:9692543\|RGD:2303718
Molecular Function	GO:0004857	enzyme inhibitor activity	LYN	IDA		Human	PMID:32958780
Molecular Function	GO:0046875	ephrin receptor binding	LYN	IPI	UniProtKB:P54764	Human	PMID:24217950
Molecular Function	GO:0043015	gamma-tubulin binding	Lyn	IDA		Rat	PMID:10545487\|RGD:8693601
Molecular Function	GO:0043208	glycosphingolipid binding	Lyn	IPI	PubChem_Compound:6450237	Rat	PMID:8106508\|RGD:2303724
Molecular Function	GO:0005178	integrin binding	Lyn	IDA		Rat	PMID:15504915\|RGD:2303714
Molecular Function	GO:0004715	non-membrane spanning protein tyrosine kinase activity	LYN	IMP		Human	PMID:23555801
Molecular Function	GO:0004715	non-membrane spanning protein tyrosine kinase activity	Lyn	IMP		Mouse	MGI:MGI:5913054\|PMID:28098138
Molecular Function	GO:0051219	phosphoprotein binding	Lyn	IPI	RGD:2598	Rat	PMID:8910399\|RGD:1599952
Molecular Function	GO:0140031	phosphorylation-dependent protein binding	LYN	IPI	UniProtKB:Q8NDB2	Human	PMID:11782428
Molecular Function	GO:0005161	platelet-derived growth factor receptor binding	Lyn	IPI	RGD:3284	Rat	PMID:15504915\|RGD:2303714
Molecular Function	GO:0005515	protein binding	LYN	IPI	UniProtKB:P27815	Human	PMID:11306681
Molecular Function	GO:0005515	protein binding	LYN	IPI	UniProtKB:O75807	Human	PMID:11517336
Molecular Function	GO:0005515	protein binding	LYN	IPI	UniProtKB:Q8NDB2	Human	PMID:11782428
Molecular Function	GO:0005515	protein binding	LYN	IPI	UniProtKB:O92972	Human	PMID:14993658
Molecular Function	GO:0005515	protein binding	LYN	IPI	UniProtKB:P27958	Human	PMID:14993658
Molecular Function	GO:0005515	protein binding	LYN	IPI	UniProtKB:Q9WMX2	Human	PMID:14993658
Molecular Function	GO:0005515	protein binding	LYN	IPI	UniProtKB:Q8R5G7	Human	PMID:15546919
Molecular Function	GO:0005515	protein binding	LYN	IPI	UniProtKB:O92972	Human	PMID:15784897
Molecular Function	GO:0005515	protein binding	LYN	IPI	UniProtKB:P27958	Human	PMID:15784897
Molecular Function	GO:0005515	protein binding	LYN	IPI	UniProtKB:Q9WMX2	Human	PMID:15784897
Molecular Function	GO:0005515	protein binding	LYN	IPI	UniProtKB:P22575	Human	PMID:16155203
Molecular Function	GO:0005515	protein binding	LYN	IPI	UniProtKB:Q13444	Human	PMID:16374509
Molecular Function	GO:0005515	protein binding	LYN	IPI	UniProtKB:P00533	Human	PMID:16799092
Molecular Function	GO:0005515	protein binding	LYN	IPI	UniProtKB:Q9HCN6	Human	PMID:1715582
Molecular Function	GO:0005515	protein binding	LYN	IPI	UniProtKB:P46527	Human	PMID:17254966
Molecular Function	GO:0005515	protein binding	LYN	IPI	UniProtKB:O60711	Human	PMID:17640867
Molecular Function	GO:0005515	protein binding	LYN	IPI	UniProtKB:P12931	Human	PMID:18070987
Molecular Function	GO:0005515	protein binding	LYN	IPI	UniProtKB:Q9NWQ8	Human	PMID:18070987
Molecular Function	GO:0005515	protein binding	LYN	IPI	UniProtKB:Q9HCN6	Human	PMID:19940238
Molecular Function	GO:0005515	protein binding	LYN	IPI	UniProtKB:Q9HCN6-1	Human	PMID:19940238
Molecular Function	GO:0005515	protein binding	LYN	IPI	UniProtKB:P16671	Human	PMID:20037584
Molecular Function	GO:0005515	protein binding	LYN	IPI	UniProtKB:Q08857	Human	PMID:20037584
Molecular Function	GO:0005515	protein binding	LYN	IPI	UniProtKB:P05556	Human	PMID:20159608
Molecular Function	GO:0005515	protein binding	LYN	IPI	UniProtKB:Q6UWF3	Human	PMID:21930792
Molecular Function	GO:0005515	protein binding	LYN	IPI	UniProtKB:P12931	Human	PMID:22581261
Molecular Function	GO:0005515	protein binding	LYN	IPI	UniProtKB:P11049	Human	PMID:22624718
Molecular Function	GO:0005515	protein binding	LYN	IPI	UniProtKB:P25063	Human	PMID:22731636
Molecular Function	GO:0005515	protein binding	LYN	IPI	UniProtKB:P08238	Human	PMID:22939624
Molecular Function	GO:0005515	protein binding	LYN	IPI	UniProtKB:P14317	Human	PMID:23001182
Molecular Function	GO:0005515	protein binding	LYN	IPI	UniProtKB:P00533	Human	PMID:23764002
Molecular Function	GO:0005515	protein binding	LYN	IPI	UniProtKB:P33993	Human	PMID:23764002
Molecular Function	GO:0005515	protein binding	LYN	IPI	UniProtKB:P00533	Human	PMID:23866081
Molecular Function	GO:0005515	protein binding	LYN	IPI	UniProtKB:P63244	Human	PMID:23866081
Molecular Function	GO:0005515	protein binding	LYN	IPI	UniProtKB:Q9NWQ8	Human	PMID:23866081
Molecular Function	GO:0005515	protein binding	LYN	IPI	UniProtKB:P00533	Human	PMID:24658140
Molecular Function	GO:0005515	protein binding	LYN	IPI	UniProtKB:P08581	Human	PMID:24728074
Molecular Function	GO:0005515	protein binding	LYN	IPI	UniProtKB:P10275	Human	PMID:24728074
Molecular Function	GO:0005515	protein binding	LYN	IPI	UniProtKB:P10721	Human	PMID:24728074
Molecular Function	GO:0005515	protein binding	LYN	IPI	UniProtKB:Q13480	Human	PMID:24728074
Molecular Function	GO:0005515	protein binding	LYN	IPI	UniProtKB:O43184	Human	PMID:25825872
Molecular Function	GO:0005515	protein binding	LYN	IPI	UniProtKB:Q13444	Human	PMID:25825872
Molecular Function	GO:0005515	protein binding	LYN	IPI	UniProtKB:P00533	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	LYN	IPI	UniProtKB:P08238	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	LYN	IPI	UniProtKB:P12931	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	LYN	IPI	UniProtKB:P01023	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LYN	IPI	UniProtKB:P05067	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LYN	IPI	UniProtKB:P07602	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LYN	IPI	UniProtKB:P27986-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LYN	IPI	UniProtKB:P37840	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LYN	IPI	UniProtKB:P50570-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LYN	IPI	UniProtKB:P51608	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LYN	IPI	UniProtKB:Q7Z699	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LYN	IPI	UniProtKB:Q96GW7	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LYN	IPI	UniProtKB:Q96L34	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LYN	IPI	UniProtKB:Q9BS26	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LYN	IPI	UniProtKB:P03406	Human	PMID:7859737
Molecular Function	GO:0005515	protein binding	LYN	IPI	UniProtKB:P20273	Human	PMID:8647200
Molecular Function	GO:0005515	protein binding	LYN	IPI	UniProtKB:P25063	Human	PMID:8753773
Molecular Function	GO:0005515	protein binding	LYN	IPI	UniProtKB:P56945	Human	PMID:9020138
Molecular Function	GO:0005515	protein binding	LYN	IPI	UniProtKB:Q6P5Z4	Human	PMID:9020138
Molecular Function	GO:0005515	protein binding	Lyn	IPI	UniProtKB:Q8CIH5	Mouse	MGI:MGI:5508323\|PMID:8395016
Molecular Function	GO:0005515	protein binding	Lyn	IPI	UniProtKB:Q9Z1S8	Mouse	MGI:MGI:3837242\|PMID:19171907
Molecular Function	GO:0005515	protein binding	Lyn	IPI	UniProtKB:P49710	Mouse	MGI:MGI:3694161\|PMID:10713104
Molecular Function	GO:0005515	protein binding	Lyn	IPI	UniProtKB:P31809\|UniProtKB:P48025	Mouse	MGI:MGI:5478702\|PMID:22496641
Molecular Function	GO:0005515	protein binding	Lyn	IPI	UniProtKB:Q60631,UniProtKB:Q8CIH5,UniProtKB:Q91YX0	Mouse	MGI:MGI:5775861\|PMID:24907343
Molecular Function	GO:0005515	protein binding	Lyn	IPI	UniProtKB:Q99N69	Mouse	MGI:MGI:3722965\|PMID:17640867
Molecular Function	GO:0005515	protein binding	Lyn	IPI	UniProtKB:Q3UU41	Mouse	MGI:MGI:5913054\|PMID:28098138
Molecular Function	GO:0005515	protein binding	Lyn	IPI	UniProtKB:O35601,UniProtKB:Q4V7G1,UniProtKB:Q9QZE2	Mouse	MGI:MGI:2654969\|PMID:12681493
Molecular Function	GO:0005515	protein binding	Lyn	IPI	PR:Q8BSM5	Mouse	PMID:11739737
Molecular Function	GO:0005515	protein binding	Lyn	IPI	PR:Q9EQR5	Mouse	PMID:16249387
Molecular Function	GO:0005515	protein binding	Lyn	IPI	PR:Q68SN8	Mouse	PMID:23509253
Molecular Function	GO:0005515	protein binding	Lyn	IPI	RGD:3821	Rat	PMID:10944523\|RGD:2303649
Molecular Function	GO:0005515	protein binding	Lyn	IPI	RGD:621367	Rat	PMID:11971018\|RGD:2303648
Molecular Function	GO:0005515	protein binding	Lyn	IPI	RGD:1562417	Rat	PMID:12681493\|RGD:1299442
Molecular Function	GO:0005515	protein binding	Lyn	IPI	RGD:2280	Rat	PMID:15710354\|RGD:2303713
Molecular Function	GO:0005515	protein binding	Lyn	IPI	RGD:628758\|RGD:3443	Rat	PMID:16713446\|RGD:1642616
Molecular Function	GO:0005515	protein binding	Lyn	IPI	RGD:70991	Rat	PMID:16785509\|RGD:2303712
Molecular Function	GO:0005515	protein binding	Lyn	IPI	UniProtKB:P58195	Rat	PMID:18579528\|RGD:2303650
Molecular Function	GO:0004672	protein kinase activity	Lyn	IDA		Mouse	PMID:9000133
Molecular Function	GO:0004713	protein tyrosine kinase activity	LYN	IDA		Human	PMID:10748115
Molecular Function	GO:0004713	protein tyrosine kinase activity	LYN	EXP		Human	PMID:10861086
Molecular Function	GO:0004713	protein tyrosine kinase activity	LYN	EXP		Human	PMID:11110698
Molecular Function	GO:0004713	protein tyrosine kinase activity	LYN	EXP		Human	PMID:11358993
Molecular Function	GO:0004713	protein tyrosine kinase activity	LYN	EXP		Human	PMID:11448999
Molecular Function	GO:0004713	protein tyrosine kinase activity	LYN	IDA		Human	PMID:11823534
Molecular Function	GO:0004713	protein tyrosine kinase activity	LYN	EXP		Human	PMID:12670955
Molecular Function	GO:0004713	protein tyrosine kinase activity	LYN	EXP		Human	PMID:12923167
Molecular Function	GO:0004713	protein tyrosine kinase activity	LYN	EXP		Human	PMID:1381360
Molecular Function	GO:0004713	protein tyrosine kinase activity	LYN	EXP		Human	PMID:16921024
Molecular Function	GO:0004713	protein tyrosine kinase activity	LYN	EXP		Human	PMID:18697750
Molecular Function	GO:0004713	protein tyrosine kinase activity	LYN	IDA		Human	PMID:32958780
Molecular Function	GO:0004713	protein tyrosine kinase activity	LYN	EXP		Human	PMID:7526393
Molecular Function	GO:0004713	protein tyrosine kinase activity	LYN	IDA		Human	PMID:7682714
Molecular Function	GO:0004713	protein tyrosine kinase activity	LYN	EXP		Human	PMID:9799234
Molecular Function	GO:0004713	protein tyrosine kinase activity	Lyn	IDA		Mouse	MGI:MGI:2152233\|PMID:11672542
Molecular Function	GO:0004713	protein tyrosine kinase activity	Lyn	IDA		Mouse	MGI:MGI:2654969\|PMID:12681493
Molecular Function	GO:0004713	protein tyrosine kinase activity	Lyn	EXP		Mouse	MGI:MGI:6217991\|PMID:12504103
Molecular Function	GO:0004713	protein tyrosine kinase activity	Lyn	EXP		Mouse	MGI:MGI:6216164\|PMID:8629002
Molecular Function	GO:0004713	protein tyrosine kinase activity	Lyn	IDA		Mouse	PMID:10872802
Molecular Function	GO:0004713	protein tyrosine kinase activity	Lyn	IDA		Mouse	PMID:7499277
Molecular Function	GO:0004713	protein tyrosine kinase activity	Lyn	IDA		Rat	PMID:12007793\|RGD:625575
Molecular Function	GO:0044877	protein-containing complex binding	Lyn	IPI	PR:P62196	Mouse	PMID:19064729
Molecular Function	GO:0044877	protein-containing complex binding	Lyn	IPI	PR:P49710	Mouse	PMID:19064729
Molecular Function	GO:0044877	protein-containing complex binding	Lyn	IPI	MGI:MGI:2444209	Mouse	PMID:19064729
Molecular Function	GO:0044877	protein-containing complex binding	Lyn	IPI	PR:Q8BZI0	Mouse	PMID:19064729
Molecular Function	GO:0044877	protein-containing complex binding	Lyn	IPI	RGD:1557394\|RGD:1563421\|RGD:708436	Rat	PMID:12681493\|RGD:1299442
Molecular Function	GO:0044877	protein-containing complex binding	Lyn	IDA		Rat	PMID:17579026\|RGD:2303709
Molecular Function	GO:0044877	protein-containing complex binding	Lyn	IDA		Rat	PMID:18234883\|RGD:2303705
Molecular Function	GO:0097110	scaffold protein binding	LYN	IPI	UniProtKB:Q8NDB2	Human	PMID:23555801
Molecular Function	GO:0017124	SH3 domain binding	Lyn	IPI	UniProtKB:A7YB12	Mouse	PMID:19064729
Molecular Function	GO:0005102	signaling receptor binding	Lyn	IPI	RGD:2599	Rat	PMID:11591756\|RGD:2303646
Molecular Function	GO:0005102	signaling receptor binding	Lyn	IPI	RGD:61978	Rat	PMID:11714805\|RGD:633160
Molecular Function	GO:0005102	signaling receptor binding	Lyn	IPI	RGD:2598	Rat	PMID:16177098\|RGD:1578516
Molecular Function	GO:0005102	signaling receptor binding	Lyn	IPI	RGD:3860	Rat	PMID:8870703\|RGD:2303644
Molecular Function	GO:0044325	transmembrane transporter binding	LYN	IPI	UniProtKB:Q9EPK8	Human	PMID:12538589
Molecular Function	GO:0044325	transmembrane transporter binding	LYN	IPI	UniProtKB:Q9HBA0	Human	PMID:12538589
Molecular Function	GO:0031625	ubiquitin protein ligase binding	Lyn	IPI	RGD:620535	Rat	PMID:14531861\|RGD:2306284
Cellular Component	GO:0005912	adherens junction	Lyn	IDA		Rat	PMID:1709169\|RGD:8693602
Cellular Component	GO:0009986	cell surface	LYN	IDA		Human	PMID:32958780
Cellular Component	GO:0005737	cytoplasm	Lyn	IDA		Mouse	MGI:MGI:3694161\|PMID:10713104
Cellular Component	GO:0009898	cytoplasmic side of plasma membrane	LYN	IDA		Human	PMID:11823534
Cellular Component	GO:0070062	extracellular exosome	LYN	HDA		Human	PMID:23533145
Cellular Component	GO:0098978	glutamatergic synapse	Lyn	IDA		Rat	PMID:14529711\|RGD:2303716
Cellular Component	GO:0005794	Golgi apparatus	LYN	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005794	Golgi apparatus	LYN	IDA		Human	PMID:15173188
Cellular Component	GO:0005794	Golgi apparatus	LYN	IDA		Human	PMID:20605918
Cellular Component	GO:0034666	integrin alpha2-beta1 complex	Lyn	IDA		Rat	PMID:18234883\|RGD:2303705
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	LYN	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016020	membrane	Lyn	IDA		Rat	PMID:16177098\|RGD:1578516
Cellular Component	GO:0045121	membrane raft	LYN	IDA		Human	PMID:11313396
Cellular Component	GO:0045121	membrane raft	Lyn	IDA		Mouse	MGI:MGI:2158591\|PMID:11826099
Cellular Component	GO:0045121	membrane raft	Lyn	IDA		Rat	PMID:18326662\|RGD:2303651
Cellular Component	GO:0030061	mitochondrial crista	Lyn	IDA		Rat	PMID:12007793\|RGD:625575
Cellular Component	GO:0005758	mitochondrial intermembrane space	Lyn	IDA		Rat	PMID:12007793\|RGD:625575
Cellular Component	GO:0031966	mitochondrial membrane	Lyn	IDA		Rat	PMID:12007793\|RGD:625575
Cellular Component	GO:0005634	nucleus	LYN	IDA		Human	PMID:18817770
Cellular Component	GO:0005634	nucleus	Lyn	IDA		Mouse	MGI:MGI:3694161\|PMID:10713104
Cellular Component	GO:0048471	perinuclear region of cytoplasm	LYN	IDA		Human	PMID:20605918
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Lyn	IDA		Rat	PMID:10545487\|RGD:8693601
Cellular Component	GO:0005886	plasma membrane	LYN	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	LYN	IDA		Human	PMID:15173188
Cellular Component	GO:0005886	plasma membrane	LYN	IDA		Human	PMID:20605918
Cellular Component	GO:0005886	plasma membrane	Lyn	IDA		Mouse	PMID:19064729
Cellular Component	GO:0005886	plasma membrane	Lyn	IDA		Rat	PMID:18579528\|RGD:2303650
Cellular Component	GO:0014069	postsynaptic density	Lyn	IDA		Rat	PMID:14529711\|RGD:2303716
Cellular Component	GO:0099091	postsynaptic specialization, intracellular component	Lyn	IDA		Rat	PMID:14529711\|RGD:2303716
Cellular Component	GO:0032991	protein-containing complex	Lyn	IDA		Mouse	MGI:MGI:2654969\|PMID:12681493
Biological Process	GO:0001782	B cell homeostasis	Lyn	IMP		Mouse	MGI:MGI:894972\|PMID:9252121
Biological Process	GO:0050853	B cell receptor signaling pathway	Lyn	IDA		Mouse	PMID:7499277
Biological Process	GO:0050853	B cell receptor signaling pathway	Lyn	IGI	MGI:MGI:3053558	Mouse	PMID:23509253
Biological Process	GO:0038159	C-X-C chemokine receptor CXCR4 signaling pathway	LYN	IMP		Human	PMID:16467205
Biological Process	GO:0031668	cellular response to extracellular stimulus	Lyn	IEP		Rat	PMID:17845203\|RGD:2303708
Biological Process	GO:0034605	cellular response to heat	Lyn	IEP		Rat	PMID:12372808\|RGD:2303719
Biological Process	GO:0071300	cellular response to retinoic acid	LYN	IMP		Human	PMID:17910947
Biological Process	GO:0097028	dendritic cell differentiation	Lyn	IMP		Mouse	MGI:MGI:3620486\|PMID:16034130
Biological Process	GO:0006974	DNA damage response	LYN	IDA		Human	PMID:10891478
Biological Process	GO:0006974	DNA damage response	LYN	IDA		Human	PMID:11517336
Biological Process	GO:0030222	eosinophil differentiation	LYN	IDA		Human	PMID:11823534
Biological Process	GO:0030218	erythrocyte differentiation	Lyn	IMP		Mouse	MGI:MGI:3694161\|PMID:10713104
Biological Process	GO:0002774	Fc receptor mediated inhibitory signaling pathway	Lyn	IMP		Mouse	MGI:MGI:3703139\|PMID:16272347
Biological Process	GO:0002431	Fc receptor mediated stimulatory signaling pathway	Lyn	IMP		Mouse	MGI:MGI:3703139\|PMID:16272347
Biological Process	GO:0002244	hematopoietic progenitor cell differentiation	LYN	IMP		Human	PMID:16467205
Biological Process	GO:0030097	hemopoiesis	Lyn	IMP		Mouse	MGI:MGI:2152233\|PMID:11672542
Biological Process	GO:0002553	histamine secretion by mast cell	Lyn	IMP		Rat	PMID:16177098\|RGD:1578516
Biological Process	GO:0002768	immune response-regulating cell surface receptor signaling pathway	Lyn	IMP		Mouse	MGI:MGI:894972\|PMID:9252121
Biological Process	GO:0038043	interleukin-5-mediated signaling pathway	LYN	IDA		Human	PMID:11823534
Biological Process	GO:0035556	intracellular signal transduction	Lyn	IDA		Mouse	PMID:9000133
Biological Process	GO:0031663	lipopolysaccharide-mediated signaling pathway	Lyn	IMP		Mouse	MGI:MGI:4456928\|PMID:20385881
Biological Process	GO:0030889	negative regulation of B cell proliferation	Lyn	IMP		Mouse	MGI:MGI:894972\|PMID:9252121
Biological Process	GO:0008285	negative regulation of cell population proliferation	LYN	IMP		Human	PMID:14726379
Biological Process	GO:0008285	negative regulation of cell population proliferation	Lyn	IMP		Mouse	MGI:MGI:3044099\|PMID:14726379
Biological Process	GO:0008285	negative regulation of cell population proliferation	Lyn	IMP		Mouse	MGI:MGI:3664842\|PMID:16116174
Biological Process	GO:0070373	negative regulation of ERK1 and ERK2 cascade	Lyn	IMP		Mouse	MGI:MGI:3044099\|PMID:14726379
Biological Process	GO:0070373	negative regulation of ERK1 and ERK2 cascade	Lyn	IMP		Mouse	MGI:MGI:2687173\|PMID:14525964
Biological Process	GO:1902532	negative regulation of intracellular signal transduction	Lyn	IMP		Mouse	MGI:MGI:2687173\|PMID:14525964
Biological Process	GO:0043407	negative regulation of MAP kinase activity	Lyn	IMP		Mouse	MGI:MGI:894972\|PMID:9252121
Biological Process	GO:0070667	negative regulation of mast cell proliferation	Lyn	IMP		Mouse	MGI:MGI:2687173\|PMID:14525964
Biological Process	GO:0002762	negative regulation of myeloid leukocyte differentiation	Lyn	IMP		Mouse	MGI:MGI:2152233\|PMID:11672542
Biological Process	GO:0001933	negative regulation of protein phosphorylation	Lyn	IMP		Mouse	MGI:MGI:2687173\|PMID:14525964
Biological Process	GO:0034136	negative regulation of toll-like receptor 2 signaling pathway	Lyn	IMP		Mouse	MGI:MGI:4456928\|PMID:20385881
Biological Process	GO:0034144	negative regulation of toll-like receptor 4 signaling pathway	Lyn	IMP		Mouse	MGI:MGI:4456928\|PMID:20385881
Biological Process	GO:0031175	neuron projection development	Lyn	IMP		Mouse	PMID:19118221
Biological Process	GO:0030593	neutrophil chemotaxis	lyn	IMP	ZFIN:ZDB-MRPHLNO-120118-1	Zfish	PMID:25582859
Biological Process	GO:0030593	neutrophil chemotaxis	lyn	IGI	ZFIN:ZDB-GENE-101026-3	Zfish	PMID:25582859
Biological Process	GO:0014003	oligodendrocyte development	Lyn	IEP		Rat	PMID:15504915\|RGD:2303714
Biological Process	GO:0018108	peptidyl-tyrosine phosphorylation	LYN	IDA		Human	PMID:11782428
Biological Process	GO:0018108	peptidyl-tyrosine phosphorylation	LYN	IDA		Human	PMID:7682714
Biological Process	GO:0018108	peptidyl-tyrosine phosphorylation	Lyn	IDA		Mouse	MGI:MGI:2152233\|PMID:11672542
Biological Process	GO:0018108	peptidyl-tyrosine phosphorylation	Lyn	IDA		Mouse	MGI:MGI:2654969\|PMID:12681493
Biological Process	GO:0018108	peptidyl-tyrosine phosphorylation	Lyn	IMP		Mouse	MGI:MGI:5913054\|PMID:28098138
Biological Process	GO:0018108	peptidyl-tyrosine phosphorylation	Lyn	IDA		Mouse	PMID:16249387
Biological Process	GO:0018108	peptidyl-tyrosine phosphorylation	Lyn	IDA		Mouse	PMID:10872802
Biological Process	GO:0018108	peptidyl-tyrosine phosphorylation	Lyn	IDA		Mouse	PMID:7499277
Biological Process	GO:0002576	platelet degranulation	Lyn	IMP		Mouse	MGI:MGI:5298337\|PMID:20189992
Biological Process	GO:1902961	positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process	LYN	IMP		Human	PMID:24217950
Biological Process	GO:0030335	positive regulation of cell migration	Lyn	IMP		Mouse	MGI:MGI:2137179\|PMID:11435302
Biological Process	GO:0008284	positive regulation of cell population proliferation	Lyn	IMP		Mouse	MGI:MGI:3694161\|PMID:10713104
Biological Process	GO:0008284	positive regulation of cell population proliferation	Lyn	IMP		Mouse	MGI:MGI:2137179\|PMID:11435302
Biological Process	GO:2000670	positive regulation of dendritic cell apoptotic process	Lyn	IMP		Mouse	MGI:MGI:3664842\|PMID:16116174
Biological Process	GO:0060369	positive regulation of Fc receptor mediated stimulatory signaling pathway	Lyn	IMP		Rat	PMID:16177098\|RGD:1578516
Biological Process	GO:0060252	positive regulation of glial cell proliferation	Lyn	IDA		Rat	PMID:15504915\|RGD:2303714
Biological Process	GO:0070668	positive regulation of mast cell proliferation	LYN	IMP		Human	PMID:11435302
Biological Process	GO:0010976	positive regulation of neuron projection development	LYN	IMP		Human	PMID:17910947
Biological Process	GO:0070447	positive regulation of oligodendrocyte progenitor proliferation	Lyn	IMP		Rat	PMID:15504915\|RGD:2303714
Biological Process	GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity	Lyn	IMP		Mouse	MGI:MGI:5297796\|PMID:8128248
Biological Process	GO:0042327	positive regulation of phosphorylation	Lyn	IMP		Rat	PMID:16177098\|RGD:1578516
Biological Process	GO:0001934	positive regulation of protein phosphorylation	LYN	IGI	UniProtKB:P20827	Human	PMID:24217950
Biological Process	GO:0070304	positive regulation of stress-activated protein kinase signaling cascade	LYN	IDA		Human	PMID:10891478
Biological Process	GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein	Lyn	IMP		Mouse	MGI:MGI:3694161\|PMID:10713104
Biological Process	GO:0046777	protein autophosphorylation	LYN	IDA		Human	PMID:7682714
Biological Process	GO:0046777	protein autophosphorylation	Lyn	IDA		Mouse	MGI:MGI:2152233\|PMID:11672542
Biological Process	GO:0046777	protein autophosphorylation	Lyn	IDA		Mouse	PMID:7499277
Biological Process	GO:0046777	protein autophosphorylation	Lyn	IDA		Mouse	PMID:9000133
Biological Process	GO:0006468	protein phosphorylation	LYN	IDA		Human	PMID:11517336
Biological Process	GO:0002902	regulation of B cell apoptotic process	Lyn	IMP		Mouse	MGI:MGI:82730\|PMID:9064343
Biological Process	GO:0050855	regulation of B cell receptor signaling pathway	Lyn	IMP		Mouse	MGI:MGI:2152233\|PMID:11672542
Biological Process	GO:0033628	regulation of cell adhesion mediated by integrin	LYN	IMP		Human	PMID:18802065
Biological Process	GO:0001817	regulation of cytokine production	Lyn	IMP		Mouse	MGI:MGI:3703139\|PMID:16272347
Biological Process	GO:0001817	regulation of cytokine production	Lyn	IMP		Mouse	MGI:MGI:4456928\|PMID:20385881
Biological Process	GO:0070372	regulation of ERK1 and ERK2 cascade	Lyn	IMP		Mouse	MGI:MGI:894972\|PMID:9252121
Biological Process	GO:0045646	regulation of erythrocyte differentiation	Lyn	IMP		Mouse	MGI:MGI:5297794\|PMID:10594694
Biological Process	GO:0050727	regulation of inflammatory response	Lyn	IMP		Mouse	MGI:MGI:3620486\|PMID:16034130
Biological Process	GO:0033003	regulation of mast cell activation	Lyn	IMP		Mouse	MGI:MGI:3703139\|PMID:16272347
Biological Process	GO:0043304	regulation of mast cell degranulation	Lyn	IMP		Mouse	MGI:MGI:3703139\|PMID:16272347
Biological Process	GO:0090025	regulation of monocyte chemotaxis	LYN	IMP		Human	PMID:18802065
Biological Process	GO:0090022	regulation of neutrophil chemotaxis	lyn	IMP	ZFIN:ZDB-MRPHLNO-120118-1	Zfish	PMID:22101434
Biological Process	GO:0090022	regulation of neutrophil chemotaxis	lyn	IMP	ZFIN:ZDB-MRPHLNO-120118-2	Zfish	PMID:22101434
Biological Process	GO:0090330	regulation of platelet aggregation	Lyn	IMP		Mouse	MGI:MGI:5298337\|PMID:20189992
Biological Process	GO:0051279	regulation of release of sequestered calcium ion into cytosol	Lyn	IGI	MGI:MGI:3053558	Mouse	PMID:23509253
Biological Process	GO:0051279	regulation of release of sequestered calcium ion into cytosol	Lyn	IMP		Rat	PMID:16177098\|RGD:1578516
Biological Process	GO:0043200	response to amino acid	Lyn	IEP		Rat	PMID:16529858\|RGD:1581410
Biological Process	GO:0048678	response to axon injury	Lyn	IEP		Rat	PMID:17918263\|RGD:2303707
Biological Process	GO:0009743	response to carbohydrate	Lyn	IEP		Rat	PMID:10330413\|RGD:2303706
Biological Process	GO:0009725	response to hormone	Lyn	IDA		Mouse	MGI:MGI:3694161\|PMID:10713104
Biological Process	GO:0032868	response to insulin	Lyn	IEP		Rat	PMID:12089355\|RGD:1299203
Biological Process	GO:0014070	response to organic cyclic compound	Lyn	IEP		Rat	PMID:15287886\|RGD:2303715
Biological Process	GO:0014070	response to organic cyclic compound	Lyn	IEP		Rat	PMID:17265464\|RGD:2303710
Biological Process	GO:0043434	response to peptide hormone	Lyn	IEP		Rat	PMID:16713446\|RGD:1642616
Biological Process	GO:0006991	response to sterol depletion	Lyn	IEP		Rat	PMID:10330413\|RGD:2303706
Biological Process	GO:0009636	response to toxic substance	Lyn	IEP		Rat	PMID:16529858\|RGD:1581410
Biological Process	GO:0009611	response to wounding	lyn	IMP	ZFIN:ZDB-MRPHLNO-120118-1	Zfish	PMID:22101434
Biological Process	GO:0009611	response to wounding	lyn	IMP	ZFIN:ZDB-MRPHLNO-120118-2	Zfish	PMID:22101434
Biological Process	GO:0009410	response to xenobiotic stimulus	Lyn	IEP		Rat	PMID:17039281\|RGD:2303711
Biological Process	GO:0002513	tolerance induction to self antigen	Lyn	IMP		Mouse	MGI:MGI:894972\|PMID:9252121
Biological Process	GO:0034142	toll-like receptor 4 signaling pathway	Lyn	IMP		Mouse	MGI:MGI:5913054\|PMID:28098138
Biological Process	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway	LYN	IMP		Human	PMID:14726379

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 05/14/2024 MGI 6.23

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.