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Term Detail
GO term:regulation of ERK1 and ERK2 cascade
Synonym: regulation of ERK1/2 cascade
Synonym: regulation of ERK1 and ERK2 signaling pathway
Synonym: regulation of ERK1 and ERK2 signalling pathway
Synonym: regulation of ERK1 cascade
Synonym: regulation of ERK2 cascade
Synonym: regulation of ERK cascade
Synonym: regulation of MAPK1 cascade
Synonym: regulation of MAPK3 cascade
GO id:GO:0070372
Definition:Any process that modulates the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade.
Number of paths to term: 92

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-aregulation of cell communication
                                                is-aregulation of signal transduction
                                                        is-aregulation of intracellular signal transduction
                                                                is-aregulation of MAPK cascade
                                                                        is-aactivation of MAPKK activity +
                                                                        is-aactivation of MAPKKK activity +
                                                                        is-anegative regulation of MAPK cascade +
                                                                        is-apositive regulation of MAPK cascade +
                                                                        is-aregulation of ERK1 and ERK2 cascade [GO:0070372] (147 genes, 182 annotations)
                                                                                is-anegative regulation of ERK1 and ERK2 cascade
                                                                                is-apositive regulation of ERK1 and ERK2 cascade +
                                                                        is-aregulation of ERK5 cascade +
                                                                        is-aregulation of MAP kinase activity +
                                                                        is-aregulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-aregulation of cellular metabolic process
                                                is-aregulation of phosphorus metabolic process
                                                        is-aregulation of phosphate metabolic process
                                                                is-aregulation of phosphorylation
                                                                        is-aregulation of MAPK cascade
                                                                                is-aactivation of MAPKK activity +
                                                                                is-aactivation of MAPKKK activity +
                                                                                is-anegative regulation of MAPK cascade +
                                                                                is-apositive regulation of MAPK cascade +
                                                                                is-aregulation of ERK1 and ERK2 cascade [GO:0070372] (147 genes, 182 annotations)
                                                                                        is-anegative regulation of ERK1 and ERK2 cascade
                                                                                        is-apositive regulation of ERK1 and ERK2 cascade +
                                                                                is-aregulation of ERK5 cascade +
                                                                                is-aregulation of MAP kinase activity +
                                                                                is-aregulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-asignal transduction
                                                is-aintracellular signal transduction
                                                        is-aMAPK cascade
                                                                is-aERK1 and ERK2 cascade
                                                                        negatively-regulatesnegative regulation of ERK1 and ERK2 cascade
                                                                        positively-regulatespositive regulation of ERK1 and ERK2 cascade +
                                                                        regulatesregulation of ERK1 and ERK2 cascade [GO:0070372] (147 genes, 182 annotations)
                                                                                is-anegative regulation of ERK1 and ERK2 cascade
                                                                                is-apositive regulation of ERK1 and ERK2 cascade +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-asignal transduction
                                                is-aintracellular signal transduction
                                                        is-aMAPK cascade
                                                                regulatesregulation of MAPK cascade
                                                                        is-aactivation of MAPKK activity +
                                                                        is-aactivation of MAPKKK activity +
                                                                        is-anegative regulation of MAPK cascade +
                                                                        is-apositive regulation of MAPK cascade +
                                                                        is-aregulation of ERK1 and ERK2 cascade [GO:0070372] (147 genes, 182 annotations)
                                                                                is-anegative regulation of ERK1 and ERK2 cascade
                                                                                is-apositive regulation of ERK1 and ERK2 cascade +
                                                                        is-aregulation of ERK5 cascade +
                                                                        is-aregulation of MAP kinase activity +
                                                                        is-aregulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-asignal transduction
                                                is-aintracellular signal transduction
                                                        regulatesregulation of intracellular signal transduction
                                                                is-aregulation of MAPK cascade
                                                                        is-aactivation of MAPKK activity +
                                                                        is-aactivation of MAPKKK activity +
                                                                        is-anegative regulation of MAPK cascade +
                                                                        is-apositive regulation of MAPK cascade +
                                                                        is-aregulation of ERK1 and ERK2 cascade [GO:0070372] (147 genes, 182 annotations)
                                                                                is-anegative regulation of ERK1 and ERK2 cascade
                                                                                is-apositive regulation of ERK1 and ERK2 cascade +
                                                                        is-aregulation of ERK5 cascade +
                                                                        is-aregulation of MAP kinase activity +
                                                                        is-aregulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-asignal transduction
                                                regulatesregulation of signal transduction
                                                        is-aregulation of intracellular signal transduction
                                                                is-aregulation of MAPK cascade
                                                                        is-aactivation of MAPKK activity +
                                                                        is-aactivation of MAPKKK activity +
                                                                        is-anegative regulation of MAPK cascade +
                                                                        is-apositive regulation of MAPK cascade +
                                                                        is-aregulation of ERK1 and ERK2 cascade [GO:0070372] (147 genes, 182 annotations)
                                                                                is-anegative regulation of ERK1 and ERK2 cascade
                                                                                is-apositive regulation of ERK1 and ERK2 cascade +
                                                                        is-aregulation of ERK5 cascade +
                                                                        is-aregulation of MAP kinase activity +
                                                                        is-aregulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-asignal transduction
                                                is-asignal transduction by phosphorylation
                                                        is-aMAPK cascade
                                                                is-aERK1 and ERK2 cascade
                                                                        negatively-regulatesnegative regulation of ERK1 and ERK2 cascade
                                                                        positively-regulatespositive regulation of ERK1 and ERK2 cascade +
                                                                        regulatesregulation of ERK1 and ERK2 cascade [GO:0070372] (147 genes, 182 annotations)
                                                                                is-anegative regulation of ERK1 and ERK2 cascade
                                                                                is-apositive regulation of ERK1 and ERK2 cascade +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-asignal transduction
                                                is-asignal transduction by phosphorylation
                                                        is-aMAPK cascade
                                                                regulatesregulation of MAPK cascade
                                                                        is-aactivation of MAPKK activity +
                                                                        is-aactivation of MAPKKK activity +
                                                                        is-anegative regulation of MAPK cascade +
                                                                        is-apositive regulation of MAPK cascade +
                                                                        is-aregulation of ERK1 and ERK2 cascade [GO:0070372] (147 genes, 182 annotations)
                                                                                is-anegative regulation of ERK1 and ERK2 cascade
                                                                                is-apositive regulation of ERK1 and ERK2 cascade +
                                                                        is-aregulation of ERK5 cascade +
                                                                        is-aregulation of MAP kinase activity +
                                                                        is-aregulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of metabolic process
                                        is-aregulation of cellular metabolic process
                                                is-aregulation of phosphorus metabolic process
                                                        is-aregulation of phosphate metabolic process
                                                                is-aregulation of phosphorylation
                                                                        is-aregulation of MAPK cascade
                                                                                is-aactivation of MAPKK activity +
                                                                                is-aactivation of MAPKKK activity +
                                                                                is-anegative regulation of MAPK cascade +
                                                                                is-apositive regulation of MAPK cascade +
                                                                                is-aregulation of ERK1 and ERK2 cascade [GO:0070372] (147 genes, 182 annotations)
                                                                                        is-anegative regulation of ERK1 and ERK2 cascade
                                                                                        is-apositive regulation of ERK1 and ERK2 cascade +
                                                                                is-aregulation of ERK5 cascade +
                                                                                is-aregulation of MAP kinase activity +
                                                                                is-aregulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of response to stimulus
                                        is-aregulation of signal transduction
                                                is-aregulation of intracellular signal transduction
                                                        is-aregulation of MAPK cascade
                                                                is-aactivation of MAPKK activity +
                                                                is-aactivation of MAPKKK activity +
                                                                is-anegative regulation of MAPK cascade +
                                                                is-apositive regulation of MAPK cascade +
                                                                is-aregulation of ERK1 and ERK2 cascade [GO:0070372] (147 genes, 182 annotations)
                                                                        is-anegative regulation of ERK1 and ERK2 cascade
                                                                        is-apositive regulation of ERK1 and ERK2 cascade +
                                                                is-aregulation of ERK5 cascade +
                                                                is-aregulation of MAP kinase activity +
                                                                is-aregulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of signaling
                                        is-aregulation of signal transduction
                                                is-aregulation of intracellular signal transduction
                                                        is-aregulation of MAPK cascade
                                                                is-aactivation of MAPKK activity +
                                                                is-aactivation of MAPKKK activity +
                                                                is-anegative regulation of MAPK cascade +
                                                                is-apositive regulation of MAPK cascade +
                                                                is-aregulation of ERK1 and ERK2 cascade [GO:0070372] (147 genes, 182 annotations)
                                                                        is-anegative regulation of ERK1 and ERK2 cascade
                                                                        is-apositive regulation of ERK1 and ERK2 cascade +
                                                                is-aregulation of ERK5 cascade +
                                                                is-aregulation of MAP kinase activity +
                                                                is-aregulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-acellular metabolic process
                                is-aphosphorus metabolic process
                                        is-aphosphate-containing compound metabolic process
                                                is-aphosphorylation
                                                        regulatesregulation of phosphorylation
                                                                is-aregulation of MAPK cascade
                                                                        is-aactivation of MAPKK activity +
                                                                        is-aactivation of MAPKKK activity +
                                                                        is-anegative regulation of MAPK cascade +
                                                                        is-apositive regulation of MAPK cascade +
                                                                        is-aregulation of ERK1 and ERK2 cascade [GO:0070372] (147 genes, 182 annotations)
                                                                                is-anegative regulation of ERK1 and ERK2 cascade
                                                                                is-apositive regulation of ERK1 and ERK2 cascade +
                                                                        is-aregulation of ERK5 cascade +
                                                                        is-aregulation of MAP kinase activity +
                                                                        is-aregulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-acellular metabolic process
                                is-aphosphorus metabolic process
                                        is-aphosphate-containing compound metabolic process
                                                is-aphosphorylation
                                                        is-asignal transduction by phosphorylation
                                                                is-aMAPK cascade
                                                                        is-aERK1 and ERK2 cascade
                                                                                negatively-regulatesnegative regulation of ERK1 and ERK2 cascade
                                                                                positively-regulatespositive regulation of ERK1 and ERK2 cascade +
                                                                                regulatesregulation of ERK1 and ERK2 cascade [GO:0070372] (147 genes, 182 annotations)
                                                                                        is-anegative regulation of ERK1 and ERK2 cascade
                                                                                        is-apositive regulation of ERK1 and ERK2 cascade +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-acellular metabolic process
                                is-aphosphorus metabolic process
                                        is-aphosphate-containing compound metabolic process
                                                is-aphosphorylation
                                                        is-asignal transduction by phosphorylation
                                                                is-aMAPK cascade
                                                                        regulatesregulation of MAPK cascade
                                                                                is-aactivation of MAPKK activity +
                                                                                is-aactivation of MAPKKK activity +
                                                                                is-anegative regulation of MAPK cascade +
                                                                                is-apositive regulation of MAPK cascade +
                                                                                is-aregulation of ERK1 and ERK2 cascade [GO:0070372] (147 genes, 182 annotations)
                                                                                        is-anegative regulation of ERK1 and ERK2 cascade
                                                                                        is-apositive regulation of ERK1 and ERK2 cascade +
                                                                                is-aregulation of ERK5 cascade +
                                                                                is-aregulation of MAP kinase activity +
                                                                                is-aregulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-acellular metabolic process
                                is-aphosphorus metabolic process
                                        is-aphosphate-containing compound metabolic process
                                                regulatesregulation of phosphate metabolic process
                                                        is-aregulation of phosphorylation
                                                                is-aregulation of MAPK cascade
                                                                        is-aactivation of MAPKK activity +
                                                                        is-aactivation of MAPKKK activity +
                                                                        is-anegative regulation of MAPK cascade +
                                                                        is-apositive regulation of MAPK cascade +
                                                                        is-aregulation of ERK1 and ERK2 cascade [GO:0070372] (147 genes, 182 annotations)
                                                                                is-anegative regulation of ERK1 and ERK2 cascade
                                                                                is-apositive regulation of ERK1 and ERK2 cascade +
                                                                        is-aregulation of ERK5 cascade +
                                                                        is-aregulation of MAP kinase activity +
                                                                        is-aregulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-acellular metabolic process
                                is-aphosphorus metabolic process
                                        regulatesregulation of phosphorus metabolic process
                                                is-aregulation of phosphate metabolic process
                                                        is-aregulation of phosphorylation
                                                                is-aregulation of MAPK cascade
                                                                        is-aactivation of MAPKK activity +
                                                                        is-aactivation of MAPKKK activity +
                                                                        is-anegative regulation of MAPK cascade +
                                                                        is-apositive regulation of MAPK cascade +
                                                                        is-aregulation of ERK1 and ERK2 cascade [GO:0070372] (147 genes, 182 annotations)
                                                                                is-anegative regulation of ERK1 and ERK2 cascade
                                                                                is-apositive regulation of ERK1 and ERK2 cascade +
                                                                        is-aregulation of ERK5 cascade +
                                                                        is-aregulation of MAP kinase activity +
                                                                        is-aregulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-acellular metabolic process
                                regulatesregulation of cellular metabolic process
                                        is-aregulation of phosphorus metabolic process
                                                is-aregulation of phosphate metabolic process
                                                        is-aregulation of phosphorylation
                                                                is-aregulation of MAPK cascade
                                                                        is-aactivation of MAPKK activity +
                                                                        is-aactivation of MAPKKK activity +
                                                                        is-anegative regulation of MAPK cascade +
                                                                        is-apositive regulation of MAPK cascade +
                                                                        is-aregulation of ERK1 and ERK2 cascade [GO:0070372] (147 genes, 182 annotations)
                                                                                is-anegative regulation of ERK1 and ERK2 cascade
                                                                                is-apositive regulation of ERK1 and ERK2 cascade +
                                                                        is-aregulation of ERK5 cascade +
                                                                        is-aregulation of MAP kinase activity +
                                                                        is-aregulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-acellular response to stimulus
                                is-asignal transduction
                                        is-aintracellular signal transduction
                                                is-aMAPK cascade
                                                        is-aERK1 and ERK2 cascade
                                                                negatively-regulatesnegative regulation of ERK1 and ERK2 cascade
                                                                positively-regulatespositive regulation of ERK1 and ERK2 cascade +
                                                                regulatesregulation of ERK1 and ERK2 cascade [GO:0070372] (147 genes, 182 annotations)
                                                                        is-anegative regulation of ERK1 and ERK2 cascade
                                                                        is-apositive regulation of ERK1 and ERK2 cascade +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-acellular response to stimulus
                                is-asignal transduction
                                        is-aintracellular signal transduction
                                                is-aMAPK cascade
                                                        regulatesregulation of MAPK cascade
                                                                is-aactivation of MAPKK activity +
                                                                is-aactivation of MAPKKK activity +
                                                                is-anegative regulation of MAPK cascade +
                                                                is-apositive regulation of MAPK cascade +
                                                                is-aregulation of ERK1 and ERK2 cascade [GO:0070372] (147 genes, 182 annotations)
                                                                        is-anegative regulation of ERK1 and ERK2 cascade
                                                                        is-apositive regulation of ERK1 and ERK2 cascade +
                                                                is-aregulation of ERK5 cascade +
                                                                is-aregulation of MAP kinase activity +
                                                                is-aregulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-acellular response to stimulus
                                is-asignal transduction
                                        is-aintracellular signal transduction
                                                regulatesregulation of intracellular signal transduction
                                                        is-aregulation of MAPK cascade
                                                                is-aactivation of MAPKK activity +
                                                                is-aactivation of MAPKKK activity +
                                                                is-anegative regulation of MAPK cascade +
                                                                is-apositive regulation of MAPK cascade +
                                                                is-aregulation of ERK1 and ERK2 cascade [GO:0070372] (147 genes, 182 annotations)
                                                                        is-anegative regulation of ERK1 and ERK2 cascade
                                                                        is-apositive regulation of ERK1 and ERK2 cascade +
                                                                is-aregulation of ERK5 cascade +
                                                                is-aregulation of MAP kinase activity +
                                                                is-aregulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-acellular response to stimulus
                                is-asignal transduction
                                        regulatesregulation of signal transduction
                                                is-aregulation of intracellular signal transduction
                                                        is-aregulation of MAPK cascade
                                                                is-aactivation of MAPKK activity +
                                                                is-aactivation of MAPKKK activity +
                                                                is-anegative regulation of MAPK cascade +
                                                                is-apositive regulation of MAPK cascade +
                                                                is-aregulation of ERK1 and ERK2 cascade [GO:0070372] (147 genes, 182 annotations)
                                                                        is-anegative regulation of ERK1 and ERK2 cascade
                                                                        is-apositive regulation of ERK1 and ERK2 cascade +
                                                                is-aregulation of ERK5 cascade +
                                                                is-aregulation of MAP kinase activity +
                                                                is-aregulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-acellular response to stimulus
                                is-asignal transduction
                                        is-asignal transduction by phosphorylation
                                                is-aMAPK cascade
                                                        is-aERK1 and ERK2 cascade
                                                                negatively-regulatesnegative regulation of ERK1 and ERK2 cascade
                                                                positively-regulatespositive regulation of ERK1 and ERK2 cascade +
                                                                regulatesregulation of ERK1 and ERK2 cascade [GO:0070372] (147 genes, 182 annotations)
                                                                        is-anegative regulation of ERK1 and ERK2 cascade
                                                                        is-apositive regulation of ERK1 and ERK2 cascade +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-acellular response to stimulus
                                is-asignal transduction
                                        is-asignal transduction by phosphorylation
                                                is-aMAPK cascade
                                                        regulatesregulation of MAPK cascade
                                                                is-aactivation of MAPKK activity +
                                                                is-aactivation of MAPKKK activity +
                                                                is-anegative regulation of MAPK cascade +
                                                                is-apositive regulation of MAPK cascade +
                                                                is-aregulation of ERK1 and ERK2 cascade [GO:0070372] (147 genes, 182 annotations)
                                                                        is-anegative regulation of ERK1 and ERK2 cascade
                                                                        is-apositive regulation of ERK1 and ERK2 cascade +
                                                                is-aregulation of ERK5 cascade +
                                                                is-aregulation of MAP kinase activity +
                                                                is-aregulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        regulatesregulation of cellular process
                                is-aregulation of cell communication
                                        is-aregulation of signal transduction
                                                is-aregulation of intracellular signal transduction
                                                        is-aregulation of MAPK cascade
                                                                is-aactivation of MAPKK activity +
                                                                is-aactivation of MAPKKK activity +
                                                                is-anegative regulation of MAPK cascade +
                                                                is-apositive regulation of MAPK cascade +
                                                                is-aregulation of ERK1 and ERK2 cascade [GO:0070372] (147 genes, 182 annotations)
                                                                        is-anegative regulation of ERK1 and ERK2 cascade
                                                                        is-apositive regulation of ERK1 and ERK2 cascade +
                                                                is-aregulation of ERK5 cascade +
                                                                is-aregulation of MAP kinase activity +
                                                                is-aregulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        regulatesregulation of cellular process
                                is-aregulation of cellular metabolic process
                                        is-aregulation of phosphorus metabolic process
                                                is-aregulation of phosphate metabolic process
                                                        is-aregulation of phosphorylation
                                                                is-aregulation of MAPK cascade
                                                                        is-aactivation of MAPKK activity +
                                                                        is-aactivation of MAPKKK activity +
                                                                        is-anegative regulation of MAPK cascade +
                                                                        is-apositive regulation of MAPK cascade +
                                                                        is-aregulation of ERK1 and ERK2 cascade [GO:0070372] (147 genes, 182 annotations)
                                                                                is-anegative regulation of ERK1 and ERK2 cascade
                                                                                is-apositive regulation of ERK1 and ERK2 cascade +
                                                                        is-aregulation of ERK5 cascade +
                                                                        is-aregulation of MAP kinase activity +
                                                                        is-aregulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        regulatesregulation of cellular process
                                is-asignal transduction
                                        is-aintracellular signal transduction
                                                is-aMAPK cascade
                                                        is-aERK1 and ERK2 cascade
                                                                negatively-regulatesnegative regulation of ERK1 and ERK2 cascade
                                                                positively-regulatespositive regulation of ERK1 and ERK2 cascade +
                                                                regulatesregulation of ERK1 and ERK2 cascade [GO:0070372] (147 genes, 182 annotations)
                                                                        is-anegative regulation of ERK1 and ERK2 cascade
                                                                        is-apositive regulation of ERK1 and ERK2 cascade +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        regulatesregulation of cellular process
                                is-asignal transduction
                                        is-aintracellular signal transduction
                                                is-aMAPK cascade
                                                        regulatesregulation of MAPK cascade
                                                                is-aactivation of MAPKK activity +
                                                                is-aactivation of MAPKKK activity +
                                                                is-anegative regulation of MAPK cascade +
                                                                is-apositive regulation of MAPK cascade +
                                                                is-aregulation of ERK1 and ERK2 cascade [GO:0070372] (147 genes, 182 annotations)
                                                                        is-anegative regulation of ERK1 and ERK2 cascade
                                                                        is-apositive regulation of ERK1 and ERK2 cascade +
                                                                is-aregulation of ERK5 cascade +
                                                                is-aregulation of MAP kinase activity +
                                                                is-aregulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        regulatesregulation of cellular process
                                is-asignal transduction
                                        is-aintracellular signal transduction
                                                regulatesregulation of intracellular signal transduction
                                                        is-aregulation of MAPK cascade
                                                                is-aactivation of MAPKK activity +
                                                                is-aactivation of MAPKKK activity +
                                                                is-anegative regulation of MAPK cascade +
                                                                is-apositive regulation of MAPK cascade +
                                                                is-aregulation of ERK1 and ERK2 cascade [GO:0070372] (147 genes, 182 annotations)
                                                                        is-anegative regulation of ERK1 and ERK2 cascade
                                                                        is-apositive regulation of ERK1 and ERK2 cascade +
                                                                is-aregulation of ERK5 cascade +
                                                                is-aregulation of MAP kinase activity +
                                                                is-aregulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        regulatesregulation of cellular process
                                is-asignal transduction
                                        regulatesregulation of signal transduction
                                                is-aregulation of intracellular signal transduction
                                                        is-aregulation of MAPK cascade
                                                                is-aactivation of MAPKK activity +
                                                                is-aactivation of MAPKKK activity +
                                                                is-anegative regulation of MAPK cascade +
                                                                is-apositive regulation of MAPK cascade +
                                                                is-aregulation of ERK1 and ERK2 cascade [GO:0070372] (147 genes, 182 annotations)
                                                                        is-anegative regulation of ERK1 and ERK2 cascade
                                                                        is-apositive regulation of ERK1 and ERK2 cascade +
                                                                is-aregulation of ERK5 cascade +
                                                                is-aregulation of MAP kinase activity +
                                                                is-aregulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        regulatesregulation of cellular process
                                is-asignal transduction
                                        is-asignal transduction by phosphorylation
                                                is-aMAPK cascade
                                                        is-aERK1 and ERK2 cascade
                                                                negatively-regulatesnegative regulation of ERK1 and ERK2 cascade
                                                                positively-regulatespositive regulation of ERK1 and ERK2 cascade +
                                                                regulatesregulation of ERK1 and ERK2 cascade [GO:0070372] (147 genes, 182 annotations)
                                                                        is-anegative regulation of ERK1 and ERK2 cascade
                                                                        is-apositive regulation of ERK1 and ERK2 cascade +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        regulatesregulation of cellular process
                                is-asignal transduction
                                        is-asignal transduction by phosphorylation
                                                is-aMAPK cascade
                                                        regulatesregulation of MAPK cascade
                                                                is-aactivation of MAPKK activity +
                                                                is-aactivation of MAPKKK activity +
                                                                is-anegative regulation of MAPK cascade +
                                                                is-apositive regulation of MAPK cascade +
                                                                is-aregulation of ERK1 and ERK2 cascade [GO:0070372] (147 genes, 182 annotations)
                                                                        is-anegative regulation of ERK1 and ERK2 cascade
                                                                        is-apositive regulation of ERK1 and ERK2 cascade +
                                                                is-aregulation of ERK5 cascade +
                                                                is-aregulation of MAP kinase activity +
                                                                is-aregulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acell communication
                                        regulatesregulation of cell communication
                                                is-aregulation of signal transduction
                                                        is-aregulation of intracellular signal transduction
                                                                is-aregulation of MAPK cascade
                                                                        is-aactivation of MAPKK activity +
                                                                        is-aactivation of MAPKKK activity +
                                                                        is-anegative regulation of MAPK cascade +
                                                                        is-apositive regulation of MAPK cascade +
                                                                        is-aregulation of ERK1 and ERK2 cascade [GO:0070372] (147 genes, 182 annotations)
                                                                                is-anegative regulation of ERK1 and ERK2 cascade
                                                                                is-apositive regulation of ERK1 and ERK2 cascade +
                                                                        is-aregulation of ERK5 cascade +
                                                                        is-aregulation of MAP kinase activity +
                                                                        is-aregulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acell communication
                                        part-ofsignal transduction
                                                is-aintracellular signal transduction
                                                        is-aMAPK cascade
                                                                is-aERK1 and ERK2 cascade
                                                                        negatively-regulatesnegative regulation of ERK1 and ERK2 cascade
                                                                        positively-regulatespositive regulation of ERK1 and ERK2 cascade +
                                                                        regulatesregulation of ERK1 and ERK2 cascade [GO:0070372] (147 genes, 182 annotations)
                                                                                is-anegative regulation of ERK1 and ERK2 cascade
                                                                                is-apositive regulation of ERK1 and ERK2 cascade +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acell communication
                                        part-ofsignal transduction
                                                is-aintracellular signal transduction
                                                        is-aMAPK cascade
                                                                regulatesregulation of MAPK cascade
                                                                        is-aactivation of MAPKK activity +
                                                                        is-aactivation of MAPKKK activity +
                                                                        is-anegative regulation of MAPK cascade +
                                                                        is-apositive regulation of MAPK cascade +
                                                                        is-aregulation of ERK1 and ERK2 cascade [GO:0070372] (147 genes, 182 annotations)
                                                                                is-anegative regulation of ERK1 and ERK2 cascade
                                                                                is-apositive regulation of ERK1 and ERK2 cascade +
                                                                        is-aregulation of ERK5 cascade +
                                                                        is-aregulation of MAP kinase activity +
                                                                        is-aregulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acell communication
                                        part-ofsignal transduction
                                                is-aintracellular signal transduction
                                                        regulatesregulation of intracellular signal transduction
                                                                is-aregulation of MAPK cascade
                                                                        is-aactivation of MAPKK activity +
                                                                        is-aactivation of MAPKKK activity +
                                                                        is-anegative regulation of MAPK cascade +
                                                                        is-apositive regulation of MAPK cascade +
                                                                        is-aregulation of ERK1 and ERK2 cascade [GO:0070372] (147 genes, 182 annotations)
                                                                                is-anegative regulation of ERK1 and ERK2 cascade
                                                                                is-apositive regulation of ERK1 and ERK2 cascade +
                                                                        is-aregulation of ERK5 cascade +
                                                                        is-aregulation of MAP kinase activity +
                                                                        is-aregulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acell communication
                                        part-ofsignal transduction
                                                regulatesregulation of signal transduction
                                                        is-aregulation of intracellular signal transduction
                                                                is-aregulation of MAPK cascade
                                                                        is-aactivation of MAPKK activity +
                                                                        is-aactivation of MAPKKK activity +
                                                                        is-anegative regulation of MAPK cascade +
                                                                        is-apositive regulation of MAPK cascade +
                                                                        is-aregulation of ERK1 and ERK2 cascade [GO:0070372] (147 genes, 182 annotations)
                                                                                is-anegative regulation of ERK1 and ERK2 cascade
                                                                                is-apositive regulation of ERK1 and ERK2 cascade +
                                                                        is-aregulation of ERK5 cascade +
                                                                        is-aregulation of MAP kinase activity +
                                                                        is-aregulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acell communication
                                        part-ofsignal transduction
                                                is-asignal transduction by phosphorylation
                                                        is-aMAPK cascade
                                                                is-aERK1 and ERK2 cascade
                                                                        negatively-regulatesnegative regulation of ERK1 and ERK2 cascade
                                                                        positively-regulatespositive regulation of ERK1 and ERK2 cascade +
                                                                        regulatesregulation of ERK1 and ERK2 cascade [GO:0070372] (147 genes, 182 annotations)
                                                                                is-anegative regulation of ERK1 and ERK2 cascade
                                                                                is-apositive regulation of ERK1 and ERK2 cascade +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acell communication
                                        part-ofsignal transduction
                                                is-asignal transduction by phosphorylation
                                                        is-aMAPK cascade
                                                                regulatesregulation of MAPK cascade
                                                                        is-aactivation of MAPKK activity +
                                                                        is-aactivation of MAPKKK activity +
                                                                        is-anegative regulation of MAPK cascade +
                                                                        is-apositive regulation of MAPK cascade +
                                                                        is-aregulation of ERK1 and ERK2 cascade [GO:0070372] (147 genes, 182 annotations)
                                                                                is-anegative regulation of ERK1 and ERK2 cascade
                                                                                is-apositive regulation of ERK1 and ERK2 cascade +
                                                                        is-aregulation of ERK5 cascade +
                                                                        is-aregulation of MAP kinase activity +
                                                                        is-aregulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-asignal transduction by phosphorylation
                                        is-aMAPK cascade
                                                is-aERK1 and ERK2 cascade
                                                        negatively-regulatesnegative regulation of ERK1 and ERK2 cascade
                                                        positively-regulatespositive regulation of ERK1 and ERK2 cascade +
                                                        regulatesregulation of ERK1 and ERK2 cascade [GO:0070372] (147 genes, 182 annotations)
                                                                is-anegative regulation of ERK1 and ERK2 cascade
                                                                is-apositive regulation of ERK1 and ERK2 cascade +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-asignal transduction by phosphorylation
                                        is-aMAPK cascade
                                                regulatesregulation of MAPK cascade
                                                        is-aactivation of MAPKK activity +
                                                        is-aactivation of MAPKKK activity +
                                                        is-anegative regulation of MAPK cascade +
                                                        is-apositive regulation of MAPK cascade +
                                                        is-aregulation of ERK1 and ERK2 cascade [GO:0070372] (147 genes, 182 annotations)
                                                                is-anegative regulation of ERK1 and ERK2 cascade
                                                                is-apositive regulation of ERK1 and ERK2 cascade +
                                                        is-aregulation of ERK5 cascade +
                                                        is-aregulation of MAP kinase activity +
                                                        is-aregulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-acellular metabolic process
                                is-aphosphorus metabolic process
                                        is-aphosphate-containing compound metabolic process
                                                is-aphosphorylation
                                                        regulatesregulation of phosphorylation
                                                                is-aregulation of MAPK cascade
                                                                        is-aactivation of MAPKK activity +
                                                                        is-aactivation of MAPKKK activity +
                                                                        is-anegative regulation of MAPK cascade +
                                                                        is-apositive regulation of MAPK cascade +
                                                                        is-aregulation of ERK1 and ERK2 cascade [GO:0070372] (147 genes, 182 annotations)
                                                                                is-anegative regulation of ERK1 and ERK2 cascade
                                                                                is-apositive regulation of ERK1 and ERK2 cascade +
                                                                        is-aregulation of ERK5 cascade +
                                                                        is-aregulation of MAP kinase activity +
                                                                        is-aregulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-acellular metabolic process
                                is-aphosphorus metabolic process
                                        is-aphosphate-containing compound metabolic process
                                                is-aphosphorylation
                                                        is-asignal transduction by phosphorylation
                                                                is-aMAPK cascade
                                                                        is-aERK1 and ERK2 cascade
                                                                                negatively-regulatesnegative regulation of ERK1 and ERK2 cascade
                                                                                positively-regulatespositive regulation of ERK1 and ERK2 cascade +
                                                                                regulatesregulation of ERK1 and ERK2 cascade [GO:0070372] (147 genes, 182 annotations)
                                                                                        is-anegative regulation of ERK1 and ERK2 cascade
                                                                                        is-apositive regulation of ERK1 and ERK2 cascade +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-acellular metabolic process
                                is-aphosphorus metabolic process
                                        is-aphosphate-containing compound metabolic process
                                                is-aphosphorylation
                                                        is-asignal transduction by phosphorylation
                                                                is-aMAPK cascade
                                                                        regulatesregulation of MAPK cascade
                                                                                is-aactivation of MAPKK activity +
                                                                                is-aactivation of MAPKKK activity +
                                                                                is-anegative regulation of MAPK cascade +
                                                                                is-apositive regulation of MAPK cascade +
                                                                                is-aregulation of ERK1 and ERK2 cascade [GO:0070372] (147 genes, 182 annotations)
                                                                                        is-anegative regulation of ERK1 and ERK2 cascade
                                                                                        is-apositive regulation of ERK1 and ERK2 cascade +
                                                                                is-aregulation of ERK5 cascade +
                                                                                is-aregulation of MAP kinase activity +
                                                                                is-aregulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-acellular metabolic process
                                is-aphosphorus metabolic process
                                        is-aphosphate-containing compound metabolic process
                                                regulatesregulation of phosphate metabolic process
                                                        is-aregulation of phosphorylation
                                                                is-aregulation of MAPK cascade
                                                                        is-aactivation of MAPKK activity +
                                                                        is-aactivation of MAPKKK activity +
                                                                        is-anegative regulation of MAPK cascade +
                                                                        is-apositive regulation of MAPK cascade +
                                                                        is-aregulation of ERK1 and ERK2 cascade [GO:0070372] (147 genes, 182 annotations)
                                                                                is-anegative regulation of ERK1 and ERK2 cascade
                                                                                is-apositive regulation of ERK1 and ERK2 cascade +
                                                                        is-aregulation of ERK5 cascade +
                                                                        is-aregulation of MAP kinase activity +
                                                                        is-aregulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-acellular metabolic process
                                is-aphosphorus metabolic process
                                        regulatesregulation of phosphorus metabolic process
                                                is-aregulation of phosphate metabolic process
                                                        is-aregulation of phosphorylation
                                                                is-aregulation of MAPK cascade
                                                                        is-aactivation of MAPKK activity +
                                                                        is-aactivation of MAPKKK activity +
                                                                        is-anegative regulation of MAPK cascade +
                                                                        is-apositive regulation of MAPK cascade +
                                                                        is-aregulation of ERK1 and ERK2 cascade [GO:0070372] (147 genes, 182 annotations)
                                                                                is-anegative regulation of ERK1 and ERK2 cascade
                                                                                is-apositive regulation of ERK1 and ERK2 cascade +
                                                                        is-aregulation of ERK5 cascade +
                                                                        is-aregulation of MAP kinase activity +
                                                                        is-aregulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-acellular metabolic process
                                regulatesregulation of cellular metabolic process
                                        is-aregulation of phosphorus metabolic process
                                                is-aregulation of phosphate metabolic process
                                                        is-aregulation of phosphorylation
                                                                is-aregulation of MAPK cascade
                                                                        is-aactivation of MAPKK activity +
                                                                        is-aactivation of MAPKKK activity +
                                                                        is-anegative regulation of MAPK cascade +
                                                                        is-apositive regulation of MAPK cascade +
                                                                        is-aregulation of ERK1 and ERK2 cascade [GO:0070372] (147 genes, 182 annotations)
                                                                                is-anegative regulation of ERK1 and ERK2 cascade
                                                                                is-apositive regulation of ERK1 and ERK2 cascade +
                                                                        is-aregulation of ERK5 cascade +
                                                                        is-aregulation of MAP kinase activity +
                                                                        is-aregulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        regulatesregulation of metabolic process
                                is-aregulation of cellular metabolic process
                                        is-aregulation of phosphorus metabolic process
                                                is-aregulation of phosphate metabolic process
                                                        is-aregulation of phosphorylation
                                                                is-aregulation of MAPK cascade
                                                                        is-aactivation of MAPKK activity +
                                                                        is-aactivation of MAPKKK activity +
                                                                        is-anegative regulation of MAPK cascade +
                                                                        is-apositive regulation of MAPK cascade +
                                                                        is-aregulation of ERK1 and ERK2 cascade [GO:0070372] (147 genes, 182 annotations)
                                                                                is-anegative regulation of ERK1 and ERK2 cascade
                                                                                is-apositive regulation of ERK1 and ERK2 cascade +
                                                                        is-aregulation of ERK5 cascade +
                                                                        is-aregulation of MAP kinase activity +
                                                                        is-aregulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-asingle-organism metabolic process
                                is-asignal transduction by phosphorylation
                                        is-aMAPK cascade
                                                is-aERK1 and ERK2 cascade
                                                        negatively-regulatesnegative regulation of ERK1 and ERK2 cascade
                                                        positively-regulatespositive regulation of ERK1 and ERK2 cascade +
                                                        regulatesregulation of ERK1 and ERK2 cascade [GO:0070372] (147 genes, 182 annotations)
                                                                is-anegative regulation of ERK1 and ERK2 cascade
                                                                is-apositive regulation of ERK1 and ERK2 cascade +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-asingle-organism metabolic process
                                is-asignal transduction by phosphorylation
                                        is-aMAPK cascade
                                                regulatesregulation of MAPK cascade
                                                        is-aactivation of MAPKK activity +
                                                        is-aactivation of MAPKKK activity +
                                                        is-anegative regulation of MAPK cascade +
                                                        is-apositive regulation of MAPK cascade +
                                                        is-aregulation of ERK1 and ERK2 cascade [GO:0070372] (147 genes, 182 annotations)
                                                                is-anegative regulation of ERK1 and ERK2 cascade
                                                                is-apositive regulation of ERK1 and ERK2 cascade +
                                                        is-aregulation of ERK5 cascade +
                                                        is-aregulation of MAP kinase activity +
                                                        is-aregulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                regulatesregulation of biological process
                        is-aregulation of cellular process
                                is-aregulation of cell communication
                                        is-aregulation of signal transduction
                                                is-aregulation of intracellular signal transduction
                                                        is-aregulation of MAPK cascade
                                                                is-aactivation of MAPKK activity +
                                                                is-aactivation of MAPKKK activity +
                                                                is-anegative regulation of MAPK cascade +
                                                                is-apositive regulation of MAPK cascade +
                                                                is-aregulation of ERK1 and ERK2 cascade [GO:0070372] (147 genes, 182 annotations)
                                                                        is-anegative regulation of ERK1 and ERK2 cascade
                                                                        is-apositive regulation of ERK1 and ERK2 cascade +
                                                                is-aregulation of ERK5 cascade +
                                                                is-aregulation of MAP kinase activity +
                                                                is-aregulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                regulatesregulation of biological process
                        is-aregulation of cellular process
                                is-aregulation of cellular metabolic process
                                        is-aregulation of phosphorus metabolic process
                                                is-aregulation of phosphate metabolic process
                                                        is-aregulation of phosphorylation
                                                                is-aregulation of MAPK cascade
                                                                        is-aactivation of MAPKK activity +
                                                                        is-aactivation of MAPKKK activity +
                                                                        is-anegative regulation of MAPK cascade +
                                                                        is-apositive regulation of MAPK cascade +
                                                                        is-aregulation of ERK1 and ERK2 cascade [GO:0070372] (147 genes, 182 annotations)
                                                                                is-anegative regulation of ERK1 and ERK2 cascade
                                                                                is-apositive regulation of ERK1 and ERK2 cascade +
                                                                        is-aregulation of ERK5 cascade +
                                                                        is-aregulation of MAP kinase activity +
                                                                        is-aregulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                regulatesregulation of biological process
                        is-aregulation of cellular process
                                is-asignal transduction
                                        is-aintracellular signal transduction
                                                is-aMAPK cascade
                                                        is-aERK1 and ERK2 cascade
                                                                negatively-regulatesnegative regulation of ERK1 and ERK2 cascade
                                                                positively-regulatespositive regulation of ERK1 and ERK2 cascade +
                                                                regulatesregulation of ERK1 and ERK2 cascade [GO:0070372] (147 genes, 182 annotations)
                                                                        is-anegative regulation of ERK1 and ERK2 cascade
                                                                        is-apositive regulation of ERK1 and ERK2 cascade +


Gene_Ontology
        is-abiological_process
                regulatesregulation of biological process
                        is-aregulation of cellular process
                                is-asignal transduction
                                        is-aintracellular signal transduction
                                                is-aMAPK cascade
                                                        regulatesregulation of MAPK cascade
                                                                is-aactivation of MAPKK activity +
                                                                is-aactivation of MAPKKK activity +
                                                                is-anegative regulation of MAPK cascade +
                                                                is-apositive regulation of MAPK cascade +
                                                                is-aregulation of ERK1 and ERK2 cascade [GO:0070372] (147 genes, 182 annotations)
                                                                        is-anegative regulation of ERK1 and ERK2 cascade
                                                                        is-apositive regulation of ERK1 and ERK2 cascade +
                                                                is-aregulation of ERK5 cascade +
                                                                is-aregulation of MAP kinase activity +
                                                                is-aregulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                regulatesregulation of biological process
                        is-aregulation of cellular process
                                is-asignal transduction
                                        is-aintracellular signal transduction
                                                regulatesregulation of intracellular signal transduction
                                                        is-aregulation of MAPK cascade
                                                                is-aactivation of MAPKK activity +
                                                                is-aactivation of MAPKKK activity +
                                                                is-anegative regulation of MAPK cascade +
                                                                is-apositive regulation of MAPK cascade +
                                                                is-aregulation of ERK1 and ERK2 cascade [GO:0070372] (147 genes, 182 annotations)
                                                                        is-anegative regulation of ERK1 and ERK2 cascade
                                                                        is-apositive regulation of ERK1 and ERK2 cascade +
                                                                is-aregulation of ERK5 cascade +
                                                                is-aregulation of MAP kinase activity +
                                                                is-aregulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                regulatesregulation of biological process
                        is-aregulation of cellular process
                                is-asignal transduction
                                        regulatesregulation of signal transduction
                                                is-aregulation of intracellular signal transduction
                                                        is-aregulation of MAPK cascade
                                                                is-aactivation of MAPKK activity +
                                                                is-aactivation of MAPKKK activity +
                                                                is-anegative regulation of MAPK cascade +
                                                                is-apositive regulation of MAPK cascade +
                                                                is-aregulation of ERK1 and ERK2 cascade [GO:0070372] (147 genes, 182 annotations)
                                                                        is-anegative regulation of ERK1 and ERK2 cascade
                                                                        is-apositive regulation of ERK1 and ERK2 cascade +
                                                                is-aregulation of ERK5 cascade +
                                                                is-aregulation of MAP kinase activity +
                                                                is-aregulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                regulatesregulation of biological process
                        is-aregulation of cellular process
                                is-asignal transduction
                                        is-asignal transduction by phosphorylation
                                                is-aMAPK cascade
                                                        is-aERK1 and ERK2 cascade
                                                                negatively-regulatesnegative regulation of ERK1 and ERK2 cascade
                                                                positively-regulatespositive regulation of ERK1 and ERK2 cascade +
                                                                regulatesregulation of ERK1 and ERK2 cascade [GO:0070372] (147 genes, 182 annotations)
                                                                        is-anegative regulation of ERK1 and ERK2 cascade
                                                                        is-apositive regulation of ERK1 and ERK2 cascade +


Gene_Ontology
        is-abiological_process
                regulatesregulation of biological process
                        is-aregulation of cellular process
                                is-asignal transduction
                                        is-asignal transduction by phosphorylation
                                                is-aMAPK cascade
                                                        regulatesregulation of MAPK cascade
                                                                is-aactivation of MAPKK activity +
                                                                is-aactivation of MAPKKK activity +
                                                                is-anegative regulation of MAPK cascade +
                                                                is-apositive regulation of MAPK cascade +
                                                                is-aregulation of ERK1 and ERK2 cascade [GO:0070372] (147 genes, 182 annotations)
                                                                        is-anegative regulation of ERK1 and ERK2 cascade
                                                                        is-apositive regulation of ERK1 and ERK2 cascade +
                                                                is-aregulation of ERK5 cascade +
                                                                is-aregulation of MAP kinase activity +
                                                                is-aregulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                regulatesregulation of biological process
                        is-aregulation of metabolic process
                                is-aregulation of cellular metabolic process
                                        is-aregulation of phosphorus metabolic process
                                                is-aregulation of phosphate metabolic process
                                                        is-aregulation of phosphorylation
                                                                is-aregulation of MAPK cascade
                                                                        is-aactivation of MAPKK activity +
                                                                        is-aactivation of MAPKKK activity +
                                                                        is-anegative regulation of MAPK cascade +
                                                                        is-apositive regulation of MAPK cascade +
                                                                        is-aregulation of ERK1 and ERK2 cascade [GO:0070372] (147 genes, 182 annotations)
                                                                                is-anegative regulation of ERK1 and ERK2 cascade
                                                                                is-apositive regulation of ERK1 and ERK2 cascade +
                                                                        is-aregulation of ERK5 cascade +
                                                                        is-aregulation of MAP kinase activity +
                                                                        is-aregulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                regulatesregulation of biological process
                        is-aregulation of response to stimulus
                                is-aregulation of signal transduction
                                        is-aregulation of intracellular signal transduction
                                                is-aregulation of MAPK cascade
                                                        is-aactivation of MAPKK activity +
                                                        is-aactivation of MAPKKK activity +
                                                        is-anegative regulation of MAPK cascade +
                                                        is-apositive regulation of MAPK cascade +
                                                        is-aregulation of ERK1 and ERK2 cascade [GO:0070372] (147 genes, 182 annotations)
                                                                is-anegative regulation of ERK1 and ERK2 cascade
                                                                is-apositive regulation of ERK1 and ERK2 cascade +
                                                        is-aregulation of ERK5 cascade +
                                                        is-aregulation of MAP kinase activity +
                                                        is-aregulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                regulatesregulation of biological process
                        is-aregulation of signaling
                                is-aregulation of signal transduction
                                        is-aregulation of intracellular signal transduction
                                                is-aregulation of MAPK cascade
                                                        is-aactivation of MAPKK activity +
                                                        is-aactivation of MAPKKK activity +
                                                        is-anegative regulation of MAPK cascade +
                                                        is-apositive regulation of MAPK cascade +
                                                        is-aregulation of ERK1 and ERK2 cascade [GO:0070372] (147 genes, 182 annotations)
                                                                is-anegative regulation of ERK1 and ERK2 cascade
                                                                is-apositive regulation of ERK1 and ERK2 cascade +
                                                        is-aregulation of ERK5 cascade +
                                                        is-aregulation of MAP kinase activity +
                                                        is-aregulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-acellular response to stimulus
                                is-asignal transduction
                                        is-aintracellular signal transduction
                                                is-aMAPK cascade
                                                        is-aERK1 and ERK2 cascade
                                                                negatively-regulatesnegative regulation of ERK1 and ERK2 cascade
                                                                positively-regulatespositive regulation of ERK1 and ERK2 cascade +
                                                                regulatesregulation of ERK1 and ERK2 cascade [GO:0070372] (147 genes, 182 annotations)
                                                                        is-anegative regulation of ERK1 and ERK2 cascade
                                                                        is-apositive regulation of ERK1 and ERK2 cascade +


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-acellular response to stimulus
                                is-asignal transduction
                                        is-aintracellular signal transduction
                                                is-aMAPK cascade
                                                        regulatesregulation of MAPK cascade
                                                                is-aactivation of MAPKK activity +
                                                                is-aactivation of MAPKKK activity +
                                                                is-anegative regulation of MAPK cascade +
                                                                is-apositive regulation of MAPK cascade +
                                                                is-aregulation of ERK1 and ERK2 cascade [GO:0070372] (147 genes, 182 annotations)
                                                                        is-anegative regulation of ERK1 and ERK2 cascade
                                                                        is-apositive regulation of ERK1 and ERK2 cascade +
                                                                is-aregulation of ERK5 cascade +
                                                                is-aregulation of MAP kinase activity +
                                                                is-aregulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-acellular response to stimulus
                                is-asignal transduction
                                        is-aintracellular signal transduction
                                                regulatesregulation of intracellular signal transduction
                                                        is-aregulation of MAPK cascade
                                                                is-aactivation of MAPKK activity +
                                                                is-aactivation of MAPKKK activity +
                                                                is-anegative regulation of MAPK cascade +
                                                                is-apositive regulation of MAPK cascade +
                                                                is-aregulation of ERK1 and ERK2 cascade [GO:0070372] (147 genes, 182 annotations)
                                                                        is-anegative regulation of ERK1 and ERK2 cascade
                                                                        is-apositive regulation of ERK1 and ERK2 cascade +
                                                                is-aregulation of ERK5 cascade +
                                                                is-aregulation of MAP kinase activity +
                                                                is-aregulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-acellular response to stimulus
                                is-asignal transduction
                                        regulatesregulation of signal transduction
                                                is-aregulation of intracellular signal transduction
                                                        is-aregulation of MAPK cascade
                                                                is-aactivation of MAPKK activity +
                                                                is-aactivation of MAPKKK activity +
                                                                is-anegative regulation of MAPK cascade +
                                                                is-apositive regulation of MAPK cascade +
                                                                is-aregulation of ERK1 and ERK2 cascade [GO:0070372] (147 genes, 182 annotations)
                                                                        is-anegative regulation of ERK1 and ERK2 cascade
                                                                        is-apositive regulation of ERK1 and ERK2 cascade +
                                                                is-aregulation of ERK5 cascade +
                                                                is-aregulation of MAP kinase activity +
                                                                is-aregulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-acellular response to stimulus
                                is-asignal transduction
                                        is-asignal transduction by phosphorylation
                                                is-aMAPK cascade
                                                        is-aERK1 and ERK2 cascade
                                                                negatively-regulatesnegative regulation of ERK1 and ERK2 cascade
                                                                positively-regulatespositive regulation of ERK1 and ERK2 cascade +
                                                                regulatesregulation of ERK1 and ERK2 cascade [GO:0070372] (147 genes, 182 annotations)
                                                                        is-anegative regulation of ERK1 and ERK2 cascade
                                                                        is-apositive regulation of ERK1 and ERK2 cascade +


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-acellular response to stimulus
                                is-asignal transduction
                                        is-asignal transduction by phosphorylation
                                                is-aMAPK cascade
                                                        regulatesregulation of MAPK cascade
                                                                is-aactivation of MAPKK activity +
                                                                is-aactivation of MAPKKK activity +
                                                                is-anegative regulation of MAPK cascade +
                                                                is-apositive regulation of MAPK cascade +
                                                                is-aregulation of ERK1 and ERK2 cascade [GO:0070372] (147 genes, 182 annotations)
                                                                        is-anegative regulation of ERK1 and ERK2 cascade
                                                                        is-apositive regulation of ERK1 and ERK2 cascade +
                                                                is-aregulation of ERK5 cascade +
                                                                is-aregulation of MAP kinase activity +
                                                                is-aregulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        regulatesregulation of response to stimulus
                                is-aregulation of signal transduction
                                        is-aregulation of intracellular signal transduction
                                                is-aregulation of MAPK cascade
                                                        is-aactivation of MAPKK activity +
                                                        is-aactivation of MAPKKK activity +
                                                        is-anegative regulation of MAPK cascade +
                                                        is-apositive regulation of MAPK cascade +
                                                        is-aregulation of ERK1 and ERK2 cascade [GO:0070372] (147 genes, 182 annotations)
                                                                is-anegative regulation of ERK1 and ERK2 cascade
                                                                is-apositive regulation of ERK1 and ERK2 cascade +
                                                        is-aregulation of ERK5 cascade +
                                                        is-aregulation of MAP kinase activity +
                                                        is-aregulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                is-asignaling
                        is-asingle organism signaling
                                regulatesregulation of signaling
                                        is-aregulation of signal transduction
                                                is-aregulation of intracellular signal transduction
                                                        is-aregulation of MAPK cascade
                                                                is-aactivation of MAPKK activity +
                                                                is-aactivation of MAPKKK activity +
                                                                is-anegative regulation of MAPK cascade +
                                                                is-apositive regulation of MAPK cascade +
                                                                is-aregulation of ERK1 and ERK2 cascade [GO:0070372] (147 genes, 182 annotations)
                                                                        is-anegative regulation of ERK1 and ERK2 cascade
                                                                        is-apositive regulation of ERK1 and ERK2 cascade +
                                                                is-aregulation of ERK5 cascade +
                                                                is-aregulation of MAP kinase activity +
                                                                is-aregulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                is-asignaling
                        is-asingle organism signaling
                                part-ofsignal transduction
                                        is-aintracellular signal transduction
                                                is-aMAPK cascade
                                                        is-aERK1 and ERK2 cascade
                                                                negatively-regulatesnegative regulation of ERK1 and ERK2 cascade
                                                                positively-regulatespositive regulation of ERK1 and ERK2 cascade +
                                                                regulatesregulation of ERK1 and ERK2 cascade [GO:0070372] (147 genes, 182 annotations)
                                                                        is-anegative regulation of ERK1 and ERK2 cascade
                                                                        is-apositive regulation of ERK1 and ERK2 cascade +


Gene_Ontology
        is-abiological_process
                is-asignaling
                        is-asingle organism signaling
                                part-ofsignal transduction
                                        is-aintracellular signal transduction
                                                is-aMAPK cascade
                                                        regulatesregulation of MAPK cascade
                                                                is-aactivation of MAPKK activity +
                                                                is-aactivation of MAPKKK activity +
                                                                is-anegative regulation of MAPK cascade +
                                                                is-apositive regulation of MAPK cascade +
                                                                is-aregulation of ERK1 and ERK2 cascade [GO:0070372] (147 genes, 182 annotations)
                                                                        is-anegative regulation of ERK1 and ERK2 cascade
                                                                        is-apositive regulation of ERK1 and ERK2 cascade +
                                                                is-aregulation of ERK5 cascade +
                                                                is-aregulation of MAP kinase activity +
                                                                is-aregulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                is-asignaling
                        is-asingle organism signaling
                                part-ofsignal transduction
                                        is-aintracellular signal transduction
                                                regulatesregulation of intracellular signal transduction
                                                        is-aregulation of MAPK cascade
                                                                is-aactivation of MAPKK activity +
                                                                is-aactivation of MAPKKK activity +
                                                                is-anegative regulation of MAPK cascade +
                                                                is-apositive regulation of MAPK cascade +
                                                                is-aregulation of ERK1 and ERK2 cascade [GO:0070372] (147 genes, 182 annotations)
                                                                        is-anegative regulation of ERK1 and ERK2 cascade
                                                                        is-apositive regulation of ERK1 and ERK2 cascade +
                                                                is-aregulation of ERK5 cascade +
                                                                is-aregulation of MAP kinase activity +
                                                                is-aregulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                is-asignaling
                        is-asingle organism signaling
                                part-ofsignal transduction
                                        regulatesregulation of signal transduction
                                                is-aregulation of intracellular signal transduction
                                                        is-aregulation of MAPK cascade
                                                                is-aactivation of MAPKK activity +
                                                                is-aactivation of MAPKKK activity +
                                                                is-anegative regulation of MAPK cascade +
                                                                is-apositive regulation of MAPK cascade +
                                                                is-aregulation of ERK1 and ERK2 cascade [GO:0070372] (147 genes, 182 annotations)
                                                                        is-anegative regulation of ERK1 and ERK2 cascade
                                                                        is-apositive regulation of ERK1 and ERK2 cascade +
                                                                is-aregulation of ERK5 cascade +
                                                                is-aregulation of MAP kinase activity +
                                                                is-aregulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                is-asignaling
                        is-asingle organism signaling
                                part-ofsignal transduction
                                        is-asignal transduction by phosphorylation
                                                is-aMAPK cascade
                                                        is-aERK1 and ERK2 cascade
                                                                negatively-regulatesnegative regulation of ERK1 and ERK2 cascade
                                                                positively-regulatespositive regulation of ERK1 and ERK2 cascade +
                                                                regulatesregulation of ERK1 and ERK2 cascade [GO:0070372] (147 genes, 182 annotations)
                                                                        is-anegative regulation of ERK1 and ERK2 cascade
                                                                        is-apositive regulation of ERK1 and ERK2 cascade +


Gene_Ontology
        is-abiological_process
                is-asignaling
                        is-asingle organism signaling
                                part-ofsignal transduction
                                        is-asignal transduction by phosphorylation
                                                is-aMAPK cascade
                                                        regulatesregulation of MAPK cascade
                                                                is-aactivation of MAPKK activity +
                                                                is-aactivation of MAPKKK activity +
                                                                is-anegative regulation of MAPK cascade +
                                                                is-apositive regulation of MAPK cascade +
                                                                is-aregulation of ERK1 and ERK2 cascade [GO:0070372] (147 genes, 182 annotations)
                                                                        is-anegative regulation of ERK1 and ERK2 cascade
                                                                        is-apositive regulation of ERK1 and ERK2 cascade +
                                                                is-aregulation of ERK5 cascade +
                                                                is-aregulation of MAP kinase activity +
                                                                is-aregulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle organism signaling
                                regulatesregulation of signaling
                                        is-aregulation of signal transduction
                                                is-aregulation of intracellular signal transduction
                                                        is-aregulation of MAPK cascade
                                                                is-aactivation of MAPKK activity +
                                                                is-aactivation of MAPKKK activity +
                                                                is-anegative regulation of MAPK cascade +
                                                                is-apositive regulation of MAPK cascade +
                                                                is-aregulation of ERK1 and ERK2 cascade [GO:0070372] (147 genes, 182 annotations)
                                                                        is-anegative regulation of ERK1 and ERK2 cascade
                                                                        is-apositive regulation of ERK1 and ERK2 cascade +
                                                                is-aregulation of ERK5 cascade +
                                                                is-aregulation of MAP kinase activity +
                                                                is-aregulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle organism signaling
                                part-ofsignal transduction
                                        is-aintracellular signal transduction
                                                is-aMAPK cascade
                                                        is-aERK1 and ERK2 cascade
                                                                negatively-regulatesnegative regulation of ERK1 and ERK2 cascade
                                                                positively-regulatespositive regulation of ERK1 and ERK2 cascade +
                                                                regulatesregulation of ERK1 and ERK2 cascade [GO:0070372] (147 genes, 182 annotations)
                                                                        is-anegative regulation of ERK1 and ERK2 cascade
                                                                        is-apositive regulation of ERK1 and ERK2 cascade +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle organism signaling
                                part-ofsignal transduction
                                        is-aintracellular signal transduction
                                                is-aMAPK cascade
                                                        regulatesregulation of MAPK cascade
                                                                is-aactivation of MAPKK activity +
                                                                is-aactivation of MAPKKK activity +
                                                                is-anegative regulation of MAPK cascade +
                                                                is-apositive regulation of MAPK cascade +
                                                                is-aregulation of ERK1 and ERK2 cascade [GO:0070372] (147 genes, 182 annotations)
                                                                        is-anegative regulation of ERK1 and ERK2 cascade
                                                                        is-apositive regulation of ERK1 and ERK2 cascade +
                                                                is-aregulation of ERK5 cascade +
                                                                is-aregulation of MAP kinase activity +
                                                                is-aregulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle organism signaling
                                part-ofsignal transduction
                                        is-aintracellular signal transduction
                                                regulatesregulation of intracellular signal transduction
                                                        is-aregulation of MAPK cascade
                                                                is-aactivation of MAPKK activity +
                                                                is-aactivation of MAPKKK activity +
                                                                is-anegative regulation of MAPK cascade +
                                                                is-apositive regulation of MAPK cascade +
                                                                is-aregulation of ERK1 and ERK2 cascade [GO:0070372] (147 genes, 182 annotations)
                                                                        is-anegative regulation of ERK1 and ERK2 cascade
                                                                        is-apositive regulation of ERK1 and ERK2 cascade +
                                                                is-aregulation of ERK5 cascade +
                                                                is-aregulation of MAP kinase activity +
                                                                is-aregulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle organism signaling
                                part-ofsignal transduction
                                        regulatesregulation of signal transduction
                                                is-aregulation of intracellular signal transduction
                                                        is-aregulation of MAPK cascade
                                                                is-aactivation of MAPKK activity +
                                                                is-aactivation of MAPKKK activity +
                                                                is-anegative regulation of MAPK cascade +
                                                                is-apositive regulation of MAPK cascade +
                                                                is-aregulation of ERK1 and ERK2 cascade [GO:0070372] (147 genes, 182 annotations)
                                                                        is-anegative regulation of ERK1 and ERK2 cascade
                                                                        is-apositive regulation of ERK1 and ERK2 cascade +
                                                                is-aregulation of ERK5 cascade +
                                                                is-aregulation of MAP kinase activity +
                                                                is-aregulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle organism signaling
                                part-ofsignal transduction
                                        is-asignal transduction by phosphorylation
                                                is-aMAPK cascade
                                                        is-aERK1 and ERK2 cascade
                                                                negatively-regulatesnegative regulation of ERK1 and ERK2 cascade
                                                                positively-regulatespositive regulation of ERK1 and ERK2 cascade +
                                                                regulatesregulation of ERK1 and ERK2 cascade [GO:0070372] (147 genes, 182 annotations)
                                                                        is-anegative regulation of ERK1 and ERK2 cascade
                                                                        is-apositive regulation of ERK1 and ERK2 cascade +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle organism signaling
                                part-ofsignal transduction
                                        is-asignal transduction by phosphorylation
                                                is-aMAPK cascade
                                                        regulatesregulation of MAPK cascade
                                                                is-aactivation of MAPKK activity +
                                                                is-aactivation of MAPKKK activity +
                                                                is-anegative regulation of MAPK cascade +
                                                                is-apositive regulation of MAPK cascade +
                                                                is-aregulation of ERK1 and ERK2 cascade [GO:0070372] (147 genes, 182 annotations)
                                                                        is-anegative regulation of ERK1 and ERK2 cascade
                                                                        is-apositive regulation of ERK1 and ERK2 cascade +
                                                                is-aregulation of ERK5 cascade +
                                                                is-aregulation of MAP kinase activity +
                                                                is-aregulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-acell communication
                                        regulatesregulation of cell communication
                                                is-aregulation of signal transduction
                                                        is-aregulation of intracellular signal transduction
                                                                is-aregulation of MAPK cascade
                                                                        is-aactivation of MAPKK activity +
                                                                        is-aactivation of MAPKKK activity +
                                                                        is-anegative regulation of MAPK cascade +
                                                                        is-apositive regulation of MAPK cascade +
                                                                        is-aregulation of ERK1 and ERK2 cascade [GO:0070372] (147 genes, 182 annotations)
                                                                                is-anegative regulation of ERK1 and ERK2 cascade
                                                                                is-apositive regulation of ERK1 and ERK2 cascade +
                                                                        is-aregulation of ERK5 cascade +
                                                                        is-aregulation of MAP kinase activity +
                                                                        is-aregulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-acell communication
                                        part-ofsignal transduction
                                                is-aintracellular signal transduction
                                                        is-aMAPK cascade
                                                                is-aERK1 and ERK2 cascade
                                                                        negatively-regulatesnegative regulation of ERK1 and ERK2 cascade
                                                                        positively-regulatespositive regulation of ERK1 and ERK2 cascade +
                                                                        regulatesregulation of ERK1 and ERK2 cascade [GO:0070372] (147 genes, 182 annotations)
                                                                                is-anegative regulation of ERK1 and ERK2 cascade
                                                                                is-apositive regulation of ERK1 and ERK2 cascade +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-acell communication
                                        part-ofsignal transduction
                                                is-aintracellular signal transduction
                                                        is-aMAPK cascade
                                                                regulatesregulation of MAPK cascade
                                                                        is-aactivation of MAPKK activity +
                                                                        is-aactivation of MAPKKK activity +
                                                                        is-anegative regulation of MAPK cascade +
                                                                        is-apositive regulation of MAPK cascade +
                                                                        is-aregulation of ERK1 and ERK2 cascade [GO:0070372] (147 genes, 182 annotations)
                                                                                is-anegative regulation of ERK1 and ERK2 cascade
                                                                                is-apositive regulation of ERK1 and ERK2 cascade +
                                                                        is-aregulation of ERK5 cascade +
                                                                        is-aregulation of MAP kinase activity +
                                                                        is-aregulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-acell communication
                                        part-ofsignal transduction
                                                is-aintracellular signal transduction
                                                        regulatesregulation of intracellular signal transduction
                                                                is-aregulation of MAPK cascade
                                                                        is-aactivation of MAPKK activity +
                                                                        is-aactivation of MAPKKK activity +
                                                                        is-anegative regulation of MAPK cascade +
                                                                        is-apositive regulation of MAPK cascade +
                                                                        is-aregulation of ERK1 and ERK2 cascade [GO:0070372] (147 genes, 182 annotations)
                                                                                is-anegative regulation of ERK1 and ERK2 cascade
                                                                                is-apositive regulation of ERK1 and ERK2 cascade +
                                                                        is-aregulation of ERK5 cascade +
                                                                        is-aregulation of MAP kinase activity +
                                                                        is-aregulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-acell communication
                                        part-ofsignal transduction
                                                regulatesregulation of signal transduction
                                                        is-aregulation of intracellular signal transduction
                                                                is-aregulation of MAPK cascade
                                                                        is-aactivation of MAPKK activity +
                                                                        is-aactivation of MAPKKK activity +
                                                                        is-anegative regulation of MAPK cascade +
                                                                        is-apositive regulation of MAPK cascade +
                                                                        is-aregulation of ERK1 and ERK2 cascade [GO:0070372] (147 genes, 182 annotations)
                                                                                is-anegative regulation of ERK1 and ERK2 cascade
                                                                                is-apositive regulation of ERK1 and ERK2 cascade +
                                                                        is-aregulation of ERK5 cascade +
                                                                        is-aregulation of MAP kinase activity +
                                                                        is-aregulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-acell communication
                                        part-ofsignal transduction
                                                is-asignal transduction by phosphorylation
                                                        is-aMAPK cascade
                                                                is-aERK1 and ERK2 cascade
                                                                        negatively-regulatesnegative regulation of ERK1 and ERK2 cascade
                                                                        positively-regulatespositive regulation of ERK1 and ERK2 cascade +
                                                                        regulatesregulation of ERK1 and ERK2 cascade [GO:0070372] (147 genes, 182 annotations)
                                                                                is-anegative regulation of ERK1 and ERK2 cascade
                                                                                is-apositive regulation of ERK1 and ERK2 cascade +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-acell communication
                                        part-ofsignal transduction
                                                is-asignal transduction by phosphorylation
                                                        is-aMAPK cascade
                                                                regulatesregulation of MAPK cascade
                                                                        is-aactivation of MAPKK activity +
                                                                        is-aactivation of MAPKKK activity +
                                                                        is-anegative regulation of MAPK cascade +
                                                                        is-apositive regulation of MAPK cascade +
                                                                        is-aregulation of ERK1 and ERK2 cascade [GO:0070372] (147 genes, 182 annotations)
                                                                                is-anegative regulation of ERK1 and ERK2 cascade
                                                                                is-apositive regulation of ERK1 and ERK2 cascade +
                                                                        is-aregulation of ERK5 cascade +
                                                                        is-aregulation of MAP kinase activity +
                                                                        is-aregulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-asignal transduction by phosphorylation
                                        is-aMAPK cascade
                                                is-aERK1 and ERK2 cascade
                                                        negatively-regulatesnegative regulation of ERK1 and ERK2 cascade
                                                        positively-regulatespositive regulation of ERK1 and ERK2 cascade +
                                                        regulatesregulation of ERK1 and ERK2 cascade [GO:0070372] (147 genes, 182 annotations)
                                                                is-anegative regulation of ERK1 and ERK2 cascade
                                                                is-apositive regulation of ERK1 and ERK2 cascade +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-asignal transduction by phosphorylation
                                        is-aMAPK cascade
                                                regulatesregulation of MAPK cascade
                                                        is-aactivation of MAPKK activity +
                                                        is-aactivation of MAPKKK activity +
                                                        is-anegative regulation of MAPK cascade +
                                                        is-apositive regulation of MAPK cascade +
                                                        is-aregulation of ERK1 and ERK2 cascade [GO:0070372] (147 genes, 182 annotations)
                                                                is-anegative regulation of ERK1 and ERK2 cascade
                                                                is-apositive regulation of ERK1 and ERK2 cascade +
                                                        is-aregulation of ERK5 cascade +
                                                        is-aregulation of MAP kinase activity +
                                                        is-aregulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism metabolic process
                                is-asignal transduction by phosphorylation
                                        is-aMAPK cascade
                                                is-aERK1 and ERK2 cascade
                                                        negatively-regulatesnegative regulation of ERK1 and ERK2 cascade
                                                        positively-regulatespositive regulation of ERK1 and ERK2 cascade +
                                                        regulatesregulation of ERK1 and ERK2 cascade [GO:0070372] (147 genes, 182 annotations)
                                                                is-anegative regulation of ERK1 and ERK2 cascade
                                                                is-apositive regulation of ERK1 and ERK2 cascade +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism metabolic process
                                is-asignal transduction by phosphorylation
                                        is-aMAPK cascade
                                                regulatesregulation of MAPK cascade
                                                        is-aactivation of MAPKK activity +
                                                        is-aactivation of MAPKKK activity +
                                                        is-anegative regulation of MAPK cascade +
                                                        is-apositive regulation of MAPK cascade +
                                                        is-aregulation of ERK1 and ERK2 cascade [GO:0070372] (147 genes, 182 annotations)
                                                                is-anegative regulation of ERK1 and ERK2 cascade
                                                                is-apositive regulation of ERK1 and ERK2 cascade +
                                                        is-aregulation of ERK5 cascade +
                                                        is-aregulation of MAP kinase activity +
                                                        is-aregulation of stress-activated MAPK cascade +


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory