| GO term: | negative regulation of ERK1 and ERK2 cascade |
| Synonym: | down regulation of ERK1 and ERK2 cascade |
| Synonym: | down-regulation of ERK1 and ERK2 cascade |
| Synonym: | downregulation of ERK1 and ERK2 cascade |
| Synonym: | inhibition of ERK1 and ERK2 cascade |
| Synonym: | negative regulation of ERK1/2 cascade |
| Synonym: | negative regulation of ERK1 and ERK2 signaling pathway |
| Synonym: | negative regulation of ERK1 and ERK2 signalling pathway |
| Synonym: | negative regulation of ERK1 cascade |
| Synonym: | negative regulation of ERK2 cascade |
| Synonym: | negative regulation of ERK cascade |
| Synonym: | negative regulation of MAPK1 cascade |
| Synonym: | negative regulation of MAPK3 cascade |
| GO id: | GO:0070373 |
| Definition: | Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade. |
| Number of paths to term: | 218 |
denotes an 'is-a' relationship
denotes a 'part-of' relationship
denotes a 'regulates' relationship
denotes a 'positively-regulates' relationship
denotes a 'negatively-regulates' relationship
biological_processbiological regulationregulation of biological processnegative regulation of biological processnegative regulation of cellular processnegative regulation of cell communicationnegative regulation of signal transductionnegative regulation of intracellular protein kinase cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processbiological regulationregulation of biological processnegative regulation of biological processnegative regulation of response to stimulusnegative regulation of signal transductionnegative regulation of intracellular protein kinase cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processbiological regulationregulation of biological processnegative regulation of biological processnegative regulation of signalingnegative regulation of signal transductionnegative regulation of intracellular protein kinase cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processbiological regulationregulation of biological processregulation of cellular processnegative regulation of cellular processnegative regulation of cell communicationnegative regulation of signal transductionnegative regulation of intracellular protein kinase cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processbiological regulationregulation of biological processregulation of cellular processregulation of cell communicationnegative regulation of cell communicationnegative regulation of signal transductionnegative regulation of intracellular protein kinase cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processbiological regulationregulation of biological processregulation of cellular processregulation of cell communicationregulation of signal transductionnegative regulation of signal transductionnegative regulation of intracellular protein kinase cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processbiological regulationregulation of biological processregulation of cellular processregulation of cell communicationregulation of signal transductionregulation of intracellular protein kinase cascadenegative regulation of intracellular protein kinase cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processbiological regulationregulation of biological processregulation of cellular processregulation of cell communicationregulation of signal transductionregulation of intracellular protein kinase cascaderegulation of MAPK cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processbiological regulationregulation of biological processregulation of cellular processregulation of cell communicationregulation of signal transductionregulation of intracellular protein kinase cascaderegulation of MAPK cascaderegulation of ERK1 and ERK2 cascadenegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)positive regulation of ERK1 and ERK2 cascade +biological_processbiological regulationregulation of biological processregulation of cellular processsignal transductionintracellular signal transductionintracellular protein kinase cascadeMAPK cascadeERK1 and ERK2 cascadenegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)positive regulation of ERK1 and ERK2 cascade +regulation of ERK1 and ERK2 cascade +biological_processbiological regulationregulation of biological processregulation of cellular processsignal transductionintracellular signal transductionintracellular protein kinase cascadeMAPK cascadeERK1 and ERK2 cascaderegulation of ERK1 and ERK2 cascadenegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)positive regulation of ERK1 and ERK2 cascade +biological_processbiological regulationregulation of biological processregulation of cellular processsignal transductionintracellular signal transductionintracellular protein kinase cascadeMAPK cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processbiological regulationregulation of biological processregulation of cellular processsignal transductionintracellular signal transductionintracellular protein kinase cascadeMAPK cascaderegulation of MAPK cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processbiological regulationregulation of biological processregulation of cellular processsignal transductionintracellular signal transductionintracellular protein kinase cascadeMAPK cascaderegulation of MAPK cascaderegulation of ERK1 and ERK2 cascadenegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)positive regulation of ERK1 and ERK2 cascade +biological_processbiological regulationregulation of biological processregulation of cellular processsignal transductionintracellular signal transductionintracellular protein kinase cascadenegative regulation of intracellular protein kinase cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processbiological regulationregulation of biological processregulation of cellular processsignal transductionintracellular signal transductionintracellular protein kinase cascaderegulation of intracellular protein kinase cascadenegative regulation of intracellular protein kinase cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processbiological regulationregulation of biological processregulation of cellular processsignal transductionintracellular signal transductionintracellular protein kinase cascaderegulation of intracellular protein kinase cascaderegulation of MAPK cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processbiological regulationregulation of biological processregulation of cellular processsignal transductionintracellular signal transductionintracellular protein kinase cascaderegulation of intracellular protein kinase cascaderegulation of MAPK cascaderegulation of ERK1 and ERK2 cascadenegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)positive regulation of ERK1 and ERK2 cascade +biological_processbiological regulationregulation of biological processregulation of cellular processsignal transductionnegative regulation of signal transductionnegative regulation of intracellular protein kinase cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processbiological regulationregulation of biological processregulation of cellular processsignal transductionregulation of signal transductionnegative regulation of signal transductionnegative regulation of intracellular protein kinase cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processbiological regulationregulation of biological processregulation of cellular processsignal transductionregulation of signal transductionregulation of intracellular protein kinase cascadenegative regulation of intracellular protein kinase cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processbiological regulationregulation of biological processregulation of cellular processsignal transductionregulation of signal transductionregulation of intracellular protein kinase cascaderegulation of MAPK cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processbiological regulationregulation of biological processregulation of cellular processsignal transductionregulation of signal transductionregulation of intracellular protein kinase cascaderegulation of MAPK cascaderegulation of ERK1 and ERK2 cascadenegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)positive regulation of ERK1 and ERK2 cascade +biological_processbiological regulationregulation of biological processregulation of response to stimulusnegative regulation of response to stimulusnegative regulation of signal transductionnegative regulation of intracellular protein kinase cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processbiological regulationregulation of biological processregulation of response to stimulusregulation of signal transductionnegative regulation of signal transductionnegative regulation of intracellular protein kinase cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processbiological regulationregulation of biological processregulation of response to stimulusregulation of signal transductionregulation of intracellular protein kinase cascadenegative regulation of intracellular protein kinase cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processbiological regulationregulation of biological processregulation of response to stimulusregulation of signal transductionregulation of intracellular protein kinase cascaderegulation of MAPK cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processbiological regulationregulation of biological processregulation of response to stimulusregulation of signal transductionregulation of intracellular protein kinase cascaderegulation of MAPK cascaderegulation of ERK1 and ERK2 cascadenegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)positive regulation of ERK1 and ERK2 cascade +biological_processbiological regulationregulation of biological processregulation of signalingnegative regulation of signalingnegative regulation of signal transductionnegative regulation of intracellular protein kinase cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processbiological regulationregulation of biological processregulation of signalingregulation of signal transductionnegative regulation of signal transductionnegative regulation of intracellular protein kinase cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processbiological regulationregulation of biological processregulation of signalingregulation of signal transductionregulation of intracellular protein kinase cascadenegative regulation of intracellular protein kinase cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processbiological regulationregulation of biological processregulation of signalingregulation of signal transductionregulation of intracellular protein kinase cascaderegulation of MAPK cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processbiological regulationregulation of biological processregulation of signalingregulation of signal transductionregulation of intracellular protein kinase cascaderegulation of MAPK cascaderegulation of ERK1 and ERK2 cascadenegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)positive regulation of ERK1 and ERK2 cascade +biological_processcellular processnegative regulation of cellular processnegative regulation of cell communicationnegative regulation of signal transductionnegative regulation of intracellular protein kinase cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processcellular processregulation of cellular processnegative regulation of cellular processnegative regulation of cell communicationnegative regulation of signal transductionnegative regulation of intracellular protein kinase cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processcellular processregulation of cellular processregulation of cell communicationnegative regulation of cell communicationnegative regulation of signal transductionnegative regulation of intracellular protein kinase cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processcellular processregulation of cellular processregulation of cell communicationregulation of signal transductionnegative regulation of signal transductionnegative regulation of intracellular protein kinase cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processcellular processregulation of cellular processregulation of cell communicationregulation of signal transductionregulation of intracellular protein kinase cascadenegative regulation of intracellular protein kinase cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processcellular processregulation of cellular processregulation of cell communicationregulation of signal transductionregulation of intracellular protein kinase cascaderegulation of MAPK cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processcellular processregulation of cellular processregulation of cell communicationregulation of signal transductionregulation of intracellular protein kinase cascaderegulation of MAPK cascaderegulation of ERK1 and ERK2 cascadenegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)positive regulation of ERK1 and ERK2 cascade +biological_processcellular processregulation of cellular processsignal transductionintracellular signal transductionintracellular protein kinase cascadeMAPK cascadeERK1 and ERK2 cascadenegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)positive regulation of ERK1 and ERK2 cascade +regulation of ERK1 and ERK2 cascade +biological_processcellular processregulation of cellular processsignal transductionintracellular signal transductionintracellular protein kinase cascadeMAPK cascadeERK1 and ERK2 cascaderegulation of ERK1 and ERK2 cascadenegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)positive regulation of ERK1 and ERK2 cascade +biological_processcellular processregulation of cellular processsignal transductionintracellular signal transductionintracellular protein kinase cascadeMAPK cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processcellular processregulation of cellular processsignal transductionintracellular signal transductionintracellular protein kinase cascadeMAPK cascaderegulation of MAPK cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processcellular processregulation of cellular processsignal transductionintracellular signal transductionintracellular protein kinase cascadeMAPK cascaderegulation of MAPK cascaderegulation of ERK1 and ERK2 cascadenegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)positive regulation of ERK1 and ERK2 cascade +biological_processcellular processregulation of cellular processsignal transductionintracellular signal transductionintracellular protein kinase cascadenegative regulation of intracellular protein kinase cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processcellular processregulation of cellular processsignal transductionintracellular signal transductionintracellular protein kinase cascaderegulation of intracellular protein kinase cascadenegative regulation of intracellular protein kinase cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processcellular processregulation of cellular processsignal transductionintracellular signal transductionintracellular protein kinase cascaderegulation of intracellular protein kinase cascaderegulation of MAPK cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processcellular processregulation of cellular processsignal transductionintracellular signal transductionintracellular protein kinase cascaderegulation of intracellular protein kinase cascaderegulation of MAPK cascaderegulation of ERK1 and ERK2 cascadenegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)positive regulation of ERK1 and ERK2 cascade +biological_processcellular processregulation of cellular processsignal transductionnegative regulation of signal transductionnegative regulation of intracellular protein kinase cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processcellular processregulation of cellular processsignal transductionregulation of signal transductionnegative regulation of signal transductionnegative regulation of intracellular protein kinase cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processcellular processregulation of cellular processsignal transductionregulation of signal transductionregulation of intracellular protein kinase cascadenegative regulation of intracellular protein kinase cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processcellular processregulation of cellular processsignal transductionregulation of signal transductionregulation of intracellular protein kinase cascaderegulation of MAPK cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processcellular processregulation of cellular processsignal transductionregulation of signal transductionregulation of intracellular protein kinase cascaderegulation of MAPK cascaderegulation of ERK1 and ERK2 cascadenegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)positive regulation of ERK1 and ERK2 cascade +biological_processcellular processsingle-organism cellular processcell communicationnegative regulation of cell communicationnegative regulation of signal transductionnegative regulation of intracellular protein kinase cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processcellular processsingle-organism cellular processcell communicationregulation of cell communicationnegative regulation of cell communicationnegative regulation of signal transductionnegative regulation of intracellular protein kinase cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processcellular processsingle-organism cellular processcell communicationregulation of cell communicationregulation of signal transductionnegative regulation of signal transductionnegative regulation of intracellular protein kinase cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processcellular processsingle-organism cellular processcell communicationregulation of cell communicationregulation of signal transductionregulation of intracellular protein kinase cascadenegative regulation of intracellular protein kinase cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processcellular processsingle-organism cellular processcell communicationregulation of cell communicationregulation of signal transductionregulation of intracellular protein kinase cascaderegulation of MAPK cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processcellular processsingle-organism cellular processcell communicationregulation of cell communicationregulation of signal transductionregulation of intracellular protein kinase cascaderegulation of MAPK cascaderegulation of ERK1 and ERK2 cascadenegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)positive regulation of ERK1 and ERK2 cascade +biological_processcellular processsingle-organism cellular processcell communicationsignal transductionintracellular signal transductionintracellular protein kinase cascadeMAPK cascadeERK1 and ERK2 cascadenegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)positive regulation of ERK1 and ERK2 cascade +regulation of ERK1 and ERK2 cascade +biological_processcellular processsingle-organism cellular processcell communicationsignal transductionintracellular signal transductionintracellular protein kinase cascadeMAPK cascadeERK1 and ERK2 cascaderegulation of ERK1 and ERK2 cascadenegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)positive regulation of ERK1 and ERK2 cascade +biological_processcellular processsingle-organism cellular processcell communicationsignal transductionintracellular signal transductionintracellular protein kinase cascadeMAPK cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processcellular processsingle-organism cellular processcell communicationsignal transductionintracellular signal transductionintracellular protein kinase cascadeMAPK cascaderegulation of MAPK cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processcellular processsingle-organism cellular processcell communicationsignal transductionintracellular signal transductionintracellular protein kinase cascadeMAPK cascaderegulation of MAPK cascaderegulation of ERK1 and ERK2 cascadenegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)positive regulation of ERK1 and ERK2 cascade +biological_processcellular processsingle-organism cellular processcell communicationsignal transductionintracellular signal transductionintracellular protein kinase cascadenegative regulation of intracellular protein kinase cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processcellular processsingle-organism cellular processcell communicationsignal transductionintracellular signal transductionintracellular protein kinase cascaderegulation of intracellular protein kinase cascadenegative regulation of intracellular protein kinase cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processcellular processsingle-organism cellular processcell communicationsignal transductionintracellular signal transductionintracellular protein kinase cascaderegulation of intracellular protein kinase cascaderegulation of MAPK cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processcellular processsingle-organism cellular processcell communicationsignal transductionintracellular signal transductionintracellular protein kinase cascaderegulation of intracellular protein kinase cascaderegulation of MAPK cascaderegulation of ERK1 and ERK2 cascadenegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)positive regulation of ERK1 and ERK2 cascade +biological_processcellular processsingle-organism cellular processcell communicationsignal transductionnegative regulation of signal transductionnegative regulation of intracellular protein kinase cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processcellular processsingle-organism cellular processcell communicationsignal transductionregulation of signal transductionnegative regulation of signal transductionnegative regulation of intracellular protein kinase cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processcellular processsingle-organism cellular processcell communicationsignal transductionregulation of signal transductionregulation of intracellular protein kinase cascadenegative regulation of intracellular protein kinase cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processcellular processsingle-organism cellular processcell communicationsignal transductionregulation of signal transductionregulation of intracellular protein kinase cascaderegulation of MAPK cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processcellular processsingle-organism cellular processcell communicationsignal transductionregulation of signal transductionregulation of intracellular protein kinase cascaderegulation of MAPK cascaderegulation of ERK1 and ERK2 cascadenegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)positive regulation of ERK1 and ERK2 cascade +biological_processcellular processsingle-organism cellular processcellular response to stimulussignal transductionintracellular signal transductionintracellular protein kinase cascadeMAPK cascadeERK1 and ERK2 cascadenegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)positive regulation of ERK1 and ERK2 cascade +regulation of ERK1 and ERK2 cascade +biological_processcellular processsingle-organism cellular processcellular response to stimulussignal transductionintracellular signal transductionintracellular protein kinase cascadeMAPK cascadeERK1 and ERK2 cascaderegulation of ERK1 and ERK2 cascadenegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)positive regulation of ERK1 and ERK2 cascade +biological_processcellular processsingle-organism cellular processcellular response to stimulussignal transductionintracellular signal transductionintracellular protein kinase cascadeMAPK cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processcellular processsingle-organism cellular processcellular response to stimulussignal transductionintracellular signal transductionintracellular protein kinase cascadeMAPK cascaderegulation of MAPK cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processcellular processsingle-organism cellular processcellular response to stimulussignal transductionintracellular signal transductionintracellular protein kinase cascadeMAPK cascaderegulation of MAPK cascaderegulation of ERK1 and ERK2 cascadenegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)positive regulation of ERK1 and ERK2 cascade +biological_processcellular processsingle-organism cellular processcellular response to stimulussignal transductionintracellular signal transductionintracellular protein kinase cascadenegative regulation of intracellular protein kinase cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processcellular processsingle-organism cellular processcellular response to stimulussignal transductionintracellular signal transductionintracellular protein kinase cascaderegulation of intracellular protein kinase cascadenegative regulation of intracellular protein kinase cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processcellular processsingle-organism cellular processcellular response to stimulussignal transductionintracellular signal transductionintracellular protein kinase cascaderegulation of intracellular protein kinase cascaderegulation of MAPK cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processcellular processsingle-organism cellular processcellular response to stimulussignal transductionintracellular signal transductionintracellular protein kinase cascaderegulation of intracellular protein kinase cascaderegulation of MAPK cascaderegulation of ERK1 and ERK2 cascadenegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)positive regulation of ERK1 and ERK2 cascade +biological_processcellular processsingle-organism cellular processcellular response to stimulussignal transductionnegative regulation of signal transductionnegative regulation of intracellular protein kinase cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processcellular processsingle-organism cellular processcellular response to stimulussignal transductionregulation of signal transductionnegative regulation of signal transductionnegative regulation of intracellular protein kinase cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processcellular processsingle-organism cellular processcellular response to stimulussignal transductionregulation of signal transductionregulation of intracellular protein kinase cascadenegative regulation of intracellular protein kinase cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processcellular processsingle-organism cellular processcellular response to stimulussignal transductionregulation of signal transductionregulation of intracellular protein kinase cascaderegulation of MAPK cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processcellular processsingle-organism cellular processcellular response to stimulussignal transductionregulation of signal transductionregulation of intracellular protein kinase cascaderegulation of MAPK cascaderegulation of ERK1 and ERK2 cascadenegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)positive regulation of ERK1 and ERK2 cascade +biological_processnegative regulation of biological processnegative regulation of cellular processnegative regulation of cell communicationnegative regulation of signal transductionnegative regulation of intracellular protein kinase cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processnegative regulation of biological processnegative regulation of response to stimulusnegative regulation of signal transductionnegative regulation of intracellular protein kinase cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processnegative regulation of biological processnegative regulation of signalingnegative regulation of signal transductionnegative regulation of intracellular protein kinase cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processregulation of biological processnegative regulation of biological processnegative regulation of cellular processnegative regulation of cell communicationnegative regulation of signal transductionnegative regulation of intracellular protein kinase cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processregulation of biological processnegative regulation of biological processnegative regulation of response to stimulusnegative regulation of signal transductionnegative regulation of intracellular protein kinase cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processregulation of biological processnegative regulation of biological processnegative regulation of signalingnegative regulation of signal transductionnegative regulation of intracellular protein kinase cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processregulation of biological processregulation of cellular processnegative regulation of cellular processnegative regulation of cell communicationnegative regulation of signal transductionnegative regulation of intracellular protein kinase cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processregulation of biological processregulation of cellular processregulation of cell communicationnegative regulation of cell communicationnegative regulation of signal transductionnegative regulation of intracellular protein kinase cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processregulation of biological processregulation of cellular processregulation of cell communicationregulation of signal transductionnegative regulation of signal transductionnegative regulation of intracellular protein kinase cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processregulation of biological processregulation of cellular processregulation of cell communicationregulation of signal transductionregulation of intracellular protein kinase cascadenegative regulation of intracellular protein kinase cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processregulation of biological processregulation of cellular processregulation of cell communicationregulation of signal transductionregulation of intracellular protein kinase cascaderegulation of MAPK cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processregulation of biological processregulation of cellular processregulation of cell communicationregulation of signal transductionregulation of intracellular protein kinase cascaderegulation of MAPK cascaderegulation of ERK1 and ERK2 cascadenegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)positive regulation of ERK1 and ERK2 cascade +biological_processregulation of biological processregulation of cellular processsignal transductionintracellular signal transductionintracellular protein kinase cascadeMAPK cascadeERK1 and ERK2 cascadenegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)positive regulation of ERK1 and ERK2 cascade +regulation of ERK1 and ERK2 cascade +biological_processregulation of biological processregulation of cellular processsignal transductionintracellular signal transductionintracellular protein kinase cascadeMAPK cascadeERK1 and ERK2 cascaderegulation of ERK1 and ERK2 cascadenegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)positive regulation of ERK1 and ERK2 cascade +biological_processregulation of biological processregulation of cellular processsignal transductionintracellular signal transductionintracellular protein kinase cascadeMAPK cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processregulation of biological processregulation of cellular processsignal transductionintracellular signal transductionintracellular protein kinase cascadeMAPK cascaderegulation of MAPK cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processregulation of biological processregulation of cellular processsignal transductionintracellular signal transductionintracellular protein kinase cascadeMAPK cascaderegulation of MAPK cascaderegulation of ERK1 and ERK2 cascadenegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)positive regulation of ERK1 and ERK2 cascade +biological_processregulation of biological processregulation of cellular processsignal transductionintracellular signal transductionintracellular protein kinase cascadenegative regulation of intracellular protein kinase cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processregulation of biological processregulation of cellular processsignal transductionintracellular signal transductionintracellular protein kinase cascaderegulation of intracellular protein kinase cascadenegative regulation of intracellular protein kinase cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processregulation of biological processregulation of cellular processsignal transductionintracellular signal transductionintracellular protein kinase cascaderegulation of intracellular protein kinase cascaderegulation of MAPK cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processregulation of biological processregulation of cellular processsignal transductionintracellular signal transductionintracellular protein kinase cascaderegulation of intracellular protein kinase cascaderegulation of MAPK cascaderegulation of ERK1 and ERK2 cascadenegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)positive regulation of ERK1 and ERK2 cascade +biological_processregulation of biological processregulation of cellular processsignal transductionnegative regulation of signal transductionnegative regulation of intracellular protein kinase cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processregulation of biological processregulation of cellular processsignal transductionregulation of signal transductionnegative regulation of signal transductionnegative regulation of intracellular protein kinase cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processregulation of biological processregulation of cellular processsignal transductionregulation of signal transductionregulation of intracellular protein kinase cascadenegative regulation of intracellular protein kinase cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processregulation of biological processregulation of cellular processsignal transductionregulation of signal transductionregulation of intracellular protein kinase cascaderegulation of MAPK cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processregulation of biological processregulation of cellular processsignal transductionregulation of signal transductionregulation of intracellular protein kinase cascaderegulation of MAPK cascaderegulation of ERK1 and ERK2 cascadenegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)positive regulation of ERK1 and ERK2 cascade +biological_processregulation of biological processregulation of response to stimulusnegative regulation of response to stimulusnegative regulation of signal transductionnegative regulation of intracellular protein kinase cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processregulation of biological processregulation of response to stimulusregulation of signal transductionnegative regulation of signal transductionnegative regulation of intracellular protein kinase cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processregulation of biological processregulation of response to stimulusregulation of signal transductionregulation of intracellular protein kinase cascadenegative regulation of intracellular protein kinase cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processregulation of biological processregulation of response to stimulusregulation of signal transductionregulation of intracellular protein kinase cascaderegulation of MAPK cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processregulation of biological processregulation of response to stimulusregulation of signal transductionregulation of intracellular protein kinase cascaderegulation of MAPK cascaderegulation of ERK1 and ERK2 cascadenegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)positive regulation of ERK1 and ERK2 cascade +biological_processregulation of biological processregulation of signalingnegative regulation of signalingnegative regulation of signal transductionnegative regulation of intracellular protein kinase cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processregulation of biological processregulation of signalingregulation of signal transductionnegative regulation of signal transductionnegative regulation of intracellular protein kinase cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processregulation of biological processregulation of signalingregulation of signal transductionregulation of intracellular protein kinase cascadenegative regulation of intracellular protein kinase cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processregulation of biological processregulation of signalingregulation of signal transductionregulation of intracellular protein kinase cascaderegulation of MAPK cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processregulation of biological processregulation of signalingregulation of signal transductionregulation of intracellular protein kinase cascaderegulation of MAPK cascaderegulation of ERK1 and ERK2 cascadenegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)positive regulation of ERK1 and ERK2 cascade +biological_processresponse to stimuluscellular response to stimulussignal transductionintracellular signal transductionintracellular protein kinase cascadeMAPK cascadeERK1 and ERK2 cascadenegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)positive regulation of ERK1 and ERK2 cascade +regulation of ERK1 and ERK2 cascade +biological_processresponse to stimuluscellular response to stimulussignal transductionintracellular signal transductionintracellular protein kinase cascadeMAPK cascadeERK1 and ERK2 cascaderegulation of ERK1 and ERK2 cascadenegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)positive regulation of ERK1 and ERK2 cascade +biological_processresponse to stimuluscellular response to stimulussignal transductionintracellular signal transductionintracellular protein kinase cascadeMAPK cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processresponse to stimuluscellular response to stimulussignal transductionintracellular signal transductionintracellular protein kinase cascadeMAPK cascaderegulation of MAPK cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processresponse to stimuluscellular response to stimulussignal transductionintracellular signal transductionintracellular protein kinase cascadeMAPK cascaderegulation of MAPK cascaderegulation of ERK1 and ERK2 cascadenegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)positive regulation of ERK1 and ERK2 cascade +biological_processresponse to stimuluscellular response to stimulussignal transductionintracellular signal transductionintracellular protein kinase cascadenegative regulation of intracellular protein kinase cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processresponse to stimuluscellular response to stimulussignal transductionintracellular signal transductionintracellular protein kinase cascaderegulation of intracellular protein kinase cascadenegative regulation of intracellular protein kinase cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processresponse to stimuluscellular response to stimulussignal transductionintracellular signal transductionintracellular protein kinase cascaderegulation of intracellular protein kinase cascaderegulation of MAPK cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processresponse to stimuluscellular response to stimulussignal transductionintracellular signal transductionintracellular protein kinase cascaderegulation of intracellular protein kinase cascaderegulation of MAPK cascaderegulation of ERK1 and ERK2 cascadenegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)positive regulation of ERK1 and ERK2 cascade +biological_processresponse to stimuluscellular response to stimulussignal transductionnegative regulation of signal transductionnegative regulation of intracellular protein kinase cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processresponse to stimuluscellular response to stimulussignal transductionregulation of signal transductionnegative regulation of signal transductionnegative regulation of intracellular protein kinase cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processresponse to stimuluscellular response to stimulussignal transductionregulation of signal transductionregulation of intracellular protein kinase cascadenegative regulation of intracellular protein kinase cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processresponse to stimuluscellular response to stimulussignal transductionregulation of signal transductionregulation of intracellular protein kinase cascaderegulation of MAPK cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processresponse to stimuluscellular response to stimulussignal transductionregulation of signal transductionregulation of intracellular protein kinase cascaderegulation of MAPK cascaderegulation of ERK1 and ERK2 cascadenegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)positive regulation of ERK1 and ERK2 cascade +biological_processresponse to stimulusnegative regulation of response to stimulusnegative regulation of signal transductionnegative regulation of intracellular protein kinase cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processresponse to stimulusregulation of response to stimulusnegative regulation of response to stimulusnegative regulation of signal transductionnegative regulation of intracellular protein kinase cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processresponse to stimulusregulation of response to stimulusregulation of signal transductionnegative regulation of signal transductionnegative regulation of intracellular protein kinase cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processresponse to stimulusregulation of response to stimulusregulation of signal transductionregulation of intracellular protein kinase cascadenegative regulation of intracellular protein kinase cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processresponse to stimulusregulation of response to stimulusregulation of signal transductionregulation of intracellular protein kinase cascaderegulation of MAPK cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processresponse to stimulusregulation of response to stimulusregulation of signal transductionregulation of intracellular protein kinase cascaderegulation of MAPK cascaderegulation of ERK1 and ERK2 cascadenegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)positive regulation of ERK1 and ERK2 cascade +biological_processsignalingsingle organism signalingnegative regulation of signalingnegative regulation of signal transductionnegative regulation of intracellular protein kinase cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processsignalingsingle organism signalingregulation of signalingnegative regulation of signalingnegative regulation of signal transductionnegative regulation of intracellular protein kinase cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processsignalingsingle organism signalingregulation of signalingregulation of signal transductionnegative regulation of signal transductionnegative regulation of intracellular protein kinase cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processsignalingsingle organism signalingregulation of signalingregulation of signal transductionregulation of intracellular protein kinase cascadenegative regulation of intracellular protein kinase cascadenegative regulation of MAPK cascadeinactivation of MAPKK activityinactivation of MAPKKK activitynegative regulation of ERK1 and ERK2 cascade [GO:0070373] (28 genes, 30 annotations)negative regulation of ERK5 cascadenegative regulation of MAP kinase activity +negative regulation of stress-activated MAPK cascade +biological_processsignalingsingle organism signaling
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