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Gene Ontology Browser
Term Detail
GO term:dendritic cell differentiation
GO id:GO:0097028
Definition:The process in which a precursor cell type acquires the specialized features of a dendritic cell. A dendritic cell is a leukocyte of dendritic lineage specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation.
CommentsNote that immunologists typically use the word 'maturation' to refer to dendritic cells undergoing the process that GO describes as 'cell differentiation'.
Number of paths to term: 18

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acellular developmental process
                                        is-acell differentiation
                                                is-aleukocyte differentiation
                                                        is-adendritic cell differentiation [GO:0097028] (33 genes, 38 annotations)
                                                                is-amature dendritic cell differentiation
                                                                is-amyeloid dendritic cell differentiation +
                                                                negatively-regulatesnegative regulation of dendritic cell differentiation
                                                                is-aplasmacytoid dendritic cell differentiation +
                                                                positively-regulatespositive regulation of dendritic cell differentiation
                                                                regulatesregulation of dendritic cell differentiation +
                                                        is-alymphocyte differentiation +
                                                        is-amononuclear cell differentiation
                                                        is-amyeloid leukocyte differentiation +
                                                        negatively-regulatesnegative regulation of leukocyte differentiation +
                                                        positively-regulatespositive regulation of leukocyte differentiation +
                                                        regulatesregulation of leukocyte differentiation +


Gene_Ontology
        is-abiological_process
                is-adevelopmental process
                        is-aanatomical structure development
                                is-aorgan development
                                        is-ahematopoietic or lymphoid organ development
                                                is-ahemopoiesis
                                                        part-ofleukocyte differentiation
                                                                is-adendritic cell differentiation [GO:0097028] (33 genes, 38 annotations)
                                                                        is-amature dendritic cell differentiation
                                                                        is-amyeloid dendritic cell differentiation +
                                                                        negatively-regulatesnegative regulation of dendritic cell differentiation
                                                                        is-aplasmacytoid dendritic cell differentiation +
                                                                        positively-regulatespositive regulation of dendritic cell differentiation
                                                                        regulatesregulation of dendritic cell differentiation +
                                                                is-alymphocyte differentiation +
                                                                is-amononuclear cell differentiation
                                                                is-amyeloid leukocyte differentiation +
                                                                negatively-regulatesnegative regulation of leukocyte differentiation +
                                                                positively-regulatespositive regulation of leukocyte differentiation +
                                                                regulatesregulation of leukocyte differentiation +


Gene_Ontology
        is-abiological_process
                is-adevelopmental process
                        is-aanatomical structure development
                                is-asystem development
                                        is-aimmune system development
                                                part-ofhematopoietic or lymphoid organ development
                                                        is-ahemopoiesis
                                                                part-ofleukocyte differentiation
                                                                        is-adendritic cell differentiation [GO:0097028] (33 genes, 38 annotations)
                                                                                is-amature dendritic cell differentiation
                                                                                is-amyeloid dendritic cell differentiation +
                                                                                negatively-regulatesnegative regulation of dendritic cell differentiation
                                                                                is-aplasmacytoid dendritic cell differentiation +
                                                                                positively-regulatespositive regulation of dendritic cell differentiation
                                                                                regulatesregulation of dendritic cell differentiation +
                                                                        is-alymphocyte differentiation +
                                                                        is-amononuclear cell differentiation
                                                                        is-amyeloid leukocyte differentiation +
                                                                        negatively-regulatesnegative regulation of leukocyte differentiation +
                                                                        positively-regulatespositive regulation of leukocyte differentiation +
                                                                        regulatesregulation of leukocyte differentiation +


Gene_Ontology
        is-abiological_process
                is-adevelopmental process
                        is-aanatomical structure development
                                is-asystem development
                                        part-oforgan development
                                                is-ahematopoietic or lymphoid organ development
                                                        is-ahemopoiesis
                                                                part-ofleukocyte differentiation
                                                                        is-adendritic cell differentiation [GO:0097028] (33 genes, 38 annotations)
                                                                                is-amature dendritic cell differentiation
                                                                                is-amyeloid dendritic cell differentiation +
                                                                                negatively-regulatesnegative regulation of dendritic cell differentiation
                                                                                is-aplasmacytoid dendritic cell differentiation +
                                                                                positively-regulatespositive regulation of dendritic cell differentiation
                                                                                regulatesregulation of dendritic cell differentiation +
                                                                        is-alymphocyte differentiation +
                                                                        is-amononuclear cell differentiation
                                                                        is-amyeloid leukocyte differentiation +
                                                                        negatively-regulatesnegative regulation of leukocyte differentiation +
                                                                        positively-regulatespositive regulation of leukocyte differentiation +
                                                                        regulatesregulation of leukocyte differentiation +


Gene_Ontology
        is-abiological_process
                is-adevelopmental process
                        is-asingle-organism developmental process
                                is-acellular developmental process
                                        is-acell differentiation
                                                is-aleukocyte differentiation
                                                        is-adendritic cell differentiation [GO:0097028] (33 genes, 38 annotations)
                                                                is-amature dendritic cell differentiation
                                                                is-amyeloid dendritic cell differentiation +
                                                                negatively-regulatesnegative regulation of dendritic cell differentiation
                                                                is-aplasmacytoid dendritic cell differentiation +
                                                                positively-regulatespositive regulation of dendritic cell differentiation
                                                                regulatesregulation of dendritic cell differentiation +
                                                        is-alymphocyte differentiation +
                                                        is-amononuclear cell differentiation
                                                        is-amyeloid leukocyte differentiation +
                                                        negatively-regulatesnegative regulation of leukocyte differentiation +
                                                        positively-regulatespositive regulation of leukocyte differentiation +
                                                        regulatesregulation of leukocyte differentiation +


Gene_Ontology
        is-abiological_process
                is-adevelopmental process
                        is-asingle-organism developmental process
                                is-ahematopoietic or lymphoid organ development
                                        is-ahemopoiesis
                                                part-ofleukocyte differentiation
                                                        is-adendritic cell differentiation [GO:0097028] (33 genes, 38 annotations)
                                                                is-amature dendritic cell differentiation
                                                                is-amyeloid dendritic cell differentiation +
                                                                negatively-regulatesnegative regulation of dendritic cell differentiation
                                                                is-aplasmacytoid dendritic cell differentiation +
                                                                positively-regulatespositive regulation of dendritic cell differentiation
                                                                regulatesregulation of dendritic cell differentiation +
                                                        is-alymphocyte differentiation +
                                                        is-amononuclear cell differentiation
                                                        is-amyeloid leukocyte differentiation +
                                                        negatively-regulatesnegative regulation of leukocyte differentiation +
                                                        positively-regulatespositive regulation of leukocyte differentiation +
                                                        regulatesregulation of leukocyte differentiation +


Gene_Ontology
        is-abiological_process
                is-adevelopmental process
                        is-asingle-organism developmental process
                                is-amulticellular organismal development
                                        part-ofsystem development
                                                is-aimmune system development
                                                        part-ofhematopoietic or lymphoid organ development
                                                                is-ahemopoiesis
                                                                        part-ofleukocyte differentiation
                                                                                is-adendritic cell differentiation [GO:0097028] (33 genes, 38 annotations)
                                                                                        is-amature dendritic cell differentiation
                                                                                        is-amyeloid dendritic cell differentiation +
                                                                                        negatively-regulatesnegative regulation of dendritic cell differentiation
                                                                                        is-aplasmacytoid dendritic cell differentiation +
                                                                                        positively-regulatespositive regulation of dendritic cell differentiation
                                                                                        regulatesregulation of dendritic cell differentiation +
                                                                                is-alymphocyte differentiation +
                                                                                is-amononuclear cell differentiation
                                                                                is-amyeloid leukocyte differentiation +
                                                                                negatively-regulatesnegative regulation of leukocyte differentiation +
                                                                                positively-regulatespositive regulation of leukocyte differentiation +
                                                                                regulatesregulation of leukocyte differentiation +


Gene_Ontology
        is-abiological_process
                is-adevelopmental process
                        is-asingle-organism developmental process
                                is-amulticellular organismal development
                                        part-ofsystem development
                                                part-oforgan development
                                                        is-ahematopoietic or lymphoid organ development
                                                                is-ahemopoiesis
                                                                        part-ofleukocyte differentiation
                                                                                is-adendritic cell differentiation [GO:0097028] (33 genes, 38 annotations)
                                                                                        is-amature dendritic cell differentiation
                                                                                        is-amyeloid dendritic cell differentiation +
                                                                                        negatively-regulatesnegative regulation of dendritic cell differentiation
                                                                                        is-aplasmacytoid dendritic cell differentiation +
                                                                                        positively-regulatespositive regulation of dendritic cell differentiation
                                                                                        regulatesregulation of dendritic cell differentiation +
                                                                                is-alymphocyte differentiation +
                                                                                is-amononuclear cell differentiation
                                                                                is-amyeloid leukocyte differentiation +
                                                                                negatively-regulatesnegative regulation of leukocyte differentiation +
                                                                                positively-regulatespositive regulation of leukocyte differentiation +
                                                                                regulatesregulation of leukocyte differentiation +


Gene_Ontology
        is-abiological_process
                is-aimmune system process
                        is-aimmune system development
                                part-ofhematopoietic or lymphoid organ development
                                        is-ahemopoiesis
                                                part-ofleukocyte differentiation
                                                        is-adendritic cell differentiation [GO:0097028] (33 genes, 38 annotations)
                                                                is-amature dendritic cell differentiation
                                                                is-amyeloid dendritic cell differentiation +
                                                                negatively-regulatesnegative regulation of dendritic cell differentiation
                                                                is-aplasmacytoid dendritic cell differentiation +
                                                                positively-regulatespositive regulation of dendritic cell differentiation
                                                                regulatesregulation of dendritic cell differentiation +
                                                        is-alymphocyte differentiation +
                                                        is-amononuclear cell differentiation
                                                        is-amyeloid leukocyte differentiation +
                                                        negatively-regulatesnegative regulation of leukocyte differentiation +
                                                        positively-regulatespositive regulation of leukocyte differentiation +
                                                        regulatesregulation of leukocyte differentiation +


Gene_Ontology
        is-abiological_process
                is-amulticellular organismal process
                        is-asingle-multicellular organism process
                                is-amulticellular organismal development
                                        part-ofsystem development
                                                is-aimmune system development
                                                        part-ofhematopoietic or lymphoid organ development
                                                                is-ahemopoiesis
                                                                        part-ofleukocyte differentiation
                                                                                is-adendritic cell differentiation [GO:0097028] (33 genes, 38 annotations)
                                                                                        is-amature dendritic cell differentiation
                                                                                        is-amyeloid dendritic cell differentiation +
                                                                                        negatively-regulatesnegative regulation of dendritic cell differentiation
                                                                                        is-aplasmacytoid dendritic cell differentiation +
                                                                                        positively-regulatespositive regulation of dendritic cell differentiation
                                                                                        regulatesregulation of dendritic cell differentiation +
                                                                                is-alymphocyte differentiation +
                                                                                is-amononuclear cell differentiation
                                                                                is-amyeloid leukocyte differentiation +
                                                                                negatively-regulatesnegative regulation of leukocyte differentiation +
                                                                                positively-regulatespositive regulation of leukocyte differentiation +
                                                                                regulatesregulation of leukocyte differentiation +


Gene_Ontology
        is-abiological_process
                is-amulticellular organismal process
                        is-asingle-multicellular organism process
                                is-amulticellular organismal development
                                        part-ofsystem development
                                                part-oforgan development
                                                        is-ahematopoietic or lymphoid organ development
                                                                is-ahemopoiesis
                                                                        part-ofleukocyte differentiation
                                                                                is-adendritic cell differentiation [GO:0097028] (33 genes, 38 annotations)
                                                                                        is-amature dendritic cell differentiation
                                                                                        is-amyeloid dendritic cell differentiation +
                                                                                        negatively-regulatesnegative regulation of dendritic cell differentiation
                                                                                        is-aplasmacytoid dendritic cell differentiation +
                                                                                        positively-regulatespositive regulation of dendritic cell differentiation
                                                                                        regulatesregulation of dendritic cell differentiation +
                                                                                is-alymphocyte differentiation +
                                                                                is-amononuclear cell differentiation
                                                                                is-amyeloid leukocyte differentiation +
                                                                                negatively-regulatesnegative regulation of leukocyte differentiation +
                                                                                positively-regulatespositive regulation of leukocyte differentiation +
                                                                                regulatesregulation of leukocyte differentiation +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-multicellular organism process
                                is-amulticellular organismal development
                                        part-ofsystem development
                                                is-aimmune system development
                                                        part-ofhematopoietic or lymphoid organ development
                                                                is-ahemopoiesis
                                                                        part-ofleukocyte differentiation
                                                                                is-adendritic cell differentiation [GO:0097028] (33 genes, 38 annotations)
                                                                                        is-amature dendritic cell differentiation
                                                                                        is-amyeloid dendritic cell differentiation +
                                                                                        negatively-regulatesnegative regulation of dendritic cell differentiation
                                                                                        is-aplasmacytoid dendritic cell differentiation +
                                                                                        positively-regulatespositive regulation of dendritic cell differentiation
                                                                                        regulatesregulation of dendritic cell differentiation +
                                                                                is-alymphocyte differentiation +
                                                                                is-amononuclear cell differentiation
                                                                                is-amyeloid leukocyte differentiation +
                                                                                negatively-regulatesnegative regulation of leukocyte differentiation +
                                                                                positively-regulatespositive regulation of leukocyte differentiation +
                                                                                regulatesregulation of leukocyte differentiation +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-multicellular organism process
                                is-amulticellular organismal development
                                        part-ofsystem development
                                                part-oforgan development
                                                        is-ahematopoietic or lymphoid organ development
                                                                is-ahemopoiesis
                                                                        part-ofleukocyte differentiation
                                                                                is-adendritic cell differentiation [GO:0097028] (33 genes, 38 annotations)
                                                                                        is-amature dendritic cell differentiation
                                                                                        is-amyeloid dendritic cell differentiation +
                                                                                        negatively-regulatesnegative regulation of dendritic cell differentiation
                                                                                        is-aplasmacytoid dendritic cell differentiation +
                                                                                        positively-regulatespositive regulation of dendritic cell differentiation
                                                                                        regulatesregulation of dendritic cell differentiation +
                                                                                is-alymphocyte differentiation +
                                                                                is-amononuclear cell differentiation
                                                                                is-amyeloid leukocyte differentiation +
                                                                                negatively-regulatesnegative regulation of leukocyte differentiation +
                                                                                positively-regulatespositive regulation of leukocyte differentiation +
                                                                                regulatesregulation of leukocyte differentiation +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-acellular developmental process
                                        is-acell differentiation
                                                is-aleukocyte differentiation
                                                        is-adendritic cell differentiation [GO:0097028] (33 genes, 38 annotations)
                                                                is-amature dendritic cell differentiation
                                                                is-amyeloid dendritic cell differentiation +
                                                                negatively-regulatesnegative regulation of dendritic cell differentiation
                                                                is-aplasmacytoid dendritic cell differentiation +
                                                                positively-regulatespositive regulation of dendritic cell differentiation
                                                                regulatesregulation of dendritic cell differentiation +
                                                        is-alymphocyte differentiation +
                                                        is-amononuclear cell differentiation
                                                        is-amyeloid leukocyte differentiation +
                                                        negatively-regulatesnegative regulation of leukocyte differentiation +
                                                        positively-regulatespositive regulation of leukocyte differentiation +
                                                        regulatesregulation of leukocyte differentiation +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism developmental process
                                is-acellular developmental process
                                        is-acell differentiation
                                                is-aleukocyte differentiation
                                                        is-adendritic cell differentiation [GO:0097028] (33 genes, 38 annotations)
                                                                is-amature dendritic cell differentiation
                                                                is-amyeloid dendritic cell differentiation +
                                                                negatively-regulatesnegative regulation of dendritic cell differentiation
                                                                is-aplasmacytoid dendritic cell differentiation +
                                                                positively-regulatespositive regulation of dendritic cell differentiation
                                                                regulatesregulation of dendritic cell differentiation +
                                                        is-alymphocyte differentiation +
                                                        is-amononuclear cell differentiation
                                                        is-amyeloid leukocyte differentiation +
                                                        negatively-regulatesnegative regulation of leukocyte differentiation +
                                                        positively-regulatespositive regulation of leukocyte differentiation +
                                                        regulatesregulation of leukocyte differentiation +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism developmental process
                                is-ahematopoietic or lymphoid organ development
                                        is-ahemopoiesis
                                                part-ofleukocyte differentiation
                                                        is-adendritic cell differentiation [GO:0097028] (33 genes, 38 annotations)
                                                                is-amature dendritic cell differentiation
                                                                is-amyeloid dendritic cell differentiation +
                                                                negatively-regulatesnegative regulation of dendritic cell differentiation
                                                                is-aplasmacytoid dendritic cell differentiation +
                                                                positively-regulatespositive regulation of dendritic cell differentiation
                                                                regulatesregulation of dendritic cell differentiation +
                                                        is-alymphocyte differentiation +
                                                        is-amononuclear cell differentiation
                                                        is-amyeloid leukocyte differentiation +
                                                        negatively-regulatesnegative regulation of leukocyte differentiation +
                                                        positively-regulatespositive regulation of leukocyte differentiation +
                                                        regulatesregulation of leukocyte differentiation +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism developmental process
                                is-amulticellular organismal development
                                        part-ofsystem development
                                                is-aimmune system development
                                                        part-ofhematopoietic or lymphoid organ development
                                                                is-ahemopoiesis
                                                                        part-ofleukocyte differentiation
                                                                                is-adendritic cell differentiation [GO:0097028] (33 genes, 38 annotations)
                                                                                        is-amature dendritic cell differentiation
                                                                                        is-amyeloid dendritic cell differentiation +
                                                                                        negatively-regulatesnegative regulation of dendritic cell differentiation
                                                                                        is-aplasmacytoid dendritic cell differentiation +
                                                                                        positively-regulatespositive regulation of dendritic cell differentiation
                                                                                        regulatesregulation of dendritic cell differentiation +
                                                                                is-alymphocyte differentiation +
                                                                                is-amononuclear cell differentiation
                                                                                is-amyeloid leukocyte differentiation +
                                                                                negatively-regulatesnegative regulation of leukocyte differentiation +
                                                                                positively-regulatespositive regulation of leukocyte differentiation +
                                                                                regulatesregulation of leukocyte differentiation +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism developmental process
                                is-amulticellular organismal development
                                        part-ofsystem development
                                                part-oforgan development
                                                        is-ahematopoietic or lymphoid organ development
                                                                is-ahemopoiesis
                                                                        part-ofleukocyte differentiation
                                                                                is-adendritic cell differentiation [GO:0097028] (33 genes, 38 annotations)
                                                                                        is-amature dendritic cell differentiation
                                                                                        is-amyeloid dendritic cell differentiation +
                                                                                        negatively-regulatesnegative regulation of dendritic cell differentiation
                                                                                        is-aplasmacytoid dendritic cell differentiation +
                                                                                        positively-regulatespositive regulation of dendritic cell differentiation
                                                                                        regulatesregulation of dendritic cell differentiation +
                                                                                is-alymphocyte differentiation +
                                                                                is-amononuclear cell differentiation
                                                                                is-amyeloid leukocyte differentiation +
                                                                                negatively-regulatesnegative regulation of leukocyte differentiation +
                                                                                positively-regulatespositive regulation of leukocyte differentiation +
                                                                                regulatesregulation of leukocyte differentiation +


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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory