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Gene Ontology Browser
Term Detail
GO term:negative regulation of MAP kinase activity
Synonym: down regulation of MAPK activity
Synonym: down-regulation of MAPK activity
Synonym: downregulation of MAPK activity
Synonym: inhibition of MAPK activity
Synonym: negative regulation of mitogen activated protein kinase activity
Synonym: negative regulation of mitogen-activated protein kinase activity
GO id:GO:0043407
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of MAP kinase activity.
Number of paths to term: 817

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-anegative regulation of biological process
                                        is-anegative regulation of cellular process
                                                is-anegative regulation of cell communication
                                                        is-anegative regulation of signal transduction
                                                                is-anegative regulation of intracellular signal transduction
                                                                        is-anegative regulation of MAPK cascade
                                                                                is-ainactivation of MAPKK activity
                                                                                is-ainactivation of MAPKKK activity
                                                                                is-anegative regulation of ERK1 and ERK2 cascade
                                                                                is-anegative regulation of ERK5 cascade
                                                                                is-anegative regulation of MAP kinase activity [GO:0043407] (60 genes, 79 annotations)
                                                                                        is-ainactivation of MAPK activity +
                                                                                        is-anegative regulation of JUN kinase activity
                                                                                is-anegative regulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-anegative regulation of biological process
                                        is-anegative regulation of cellular process
                                                is-anegative regulation of cellular metabolic process
                                                        is-anegative regulation of cellular protein metabolic process
                                                                is-anegative regulation of protein modification process
                                                                        is-anegative regulation of protein phosphorylation
                                                                                is-anegative regulation of protein kinase activity
                                                                                        is-anegative regulation of protein serine/threonine kinase activity
                                                                                                is-ainactivation of MAPKKK activity
                                                                                                is-anegative regulation of cAMP-dependent protein kinase activity
                                                                                                is-anegative regulation of cyclin-dependent protein serine/threonine kinase activity +
                                                                                                is-anegative regulation of MAP kinase activity [GO:0043407] (60 genes, 79 annotations)
                                                                                                        is-ainactivation of MAPK activity +
                                                                                                        is-anegative regulation of JUN kinase activity
                                                                                                is-anegative regulation of myosin light chain kinase activity
                                                                                                is-anegative regulation of Rho-dependent protein serine/threonine kinase activity


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-anegative regulation of biological process
                                        is-anegative regulation of cellular process
                                                is-anegative regulation of cellular metabolic process
                                                        is-anegative regulation of phosphorus metabolic process
                                                                is-anegative regulation of phosphate metabolic process
                                                                        is-anegative regulation of phosphorylation
                                                                                is-anegative regulation of MAPK cascade
                                                                                        is-ainactivation of MAPKK activity
                                                                                        is-ainactivation of MAPKKK activity
                                                                                        is-anegative regulation of ERK1 and ERK2 cascade
                                                                                        is-anegative regulation of ERK5 cascade
                                                                                        is-anegative regulation of MAP kinase activity [GO:0043407] (60 genes, 79 annotations)
                                                                                                is-ainactivation of MAPK activity +
                                                                                                is-anegative regulation of JUN kinase activity
                                                                                        is-anegative regulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-anegative regulation of biological process
                                        is-anegative regulation of cellular process
                                                is-anegative regulation of cellular metabolic process
                                                        is-anegative regulation of phosphorus metabolic process
                                                                is-anegative regulation of phosphate metabolic process
                                                                        is-anegative regulation of phosphorylation
                                                                                is-anegative regulation of protein phosphorylation
                                                                                        is-anegative regulation of protein kinase activity
                                                                                                is-anegative regulation of protein serine/threonine kinase activity
                                                                                                        is-ainactivation of MAPKKK activity
                                                                                                        is-anegative regulation of cAMP-dependent protein kinase activity
                                                                                                        is-anegative regulation of cyclin-dependent protein serine/threonine kinase activity +
                                                                                                        is-anegative regulation of MAP kinase activity [GO:0043407] (60 genes, 79 annotations)
                                                                                                                is-ainactivation of MAPK activity +
                                                                                                                is-anegative regulation of JUN kinase activity
                                                                                                        is-anegative regulation of myosin light chain kinase activity
                                                                                                        is-anegative regulation of Rho-dependent protein serine/threonine kinase activity


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-anegative regulation of biological process
                                        is-anegative regulation of metabolic process
                                                is-anegative regulation of cellular metabolic process
                                                        is-anegative regulation of cellular protein metabolic process
                                                                is-anegative regulation of protein modification process
                                                                        is-anegative regulation of protein phosphorylation
                                                                                is-anegative regulation of protein kinase activity
                                                                                        is-anegative regulation of protein serine/threonine kinase activity
                                                                                                is-ainactivation of MAPKKK activity
                                                                                                is-anegative regulation of cAMP-dependent protein kinase activity
                                                                                                is-anegative regulation of cyclin-dependent protein serine/threonine kinase activity +
                                                                                                is-anegative regulation of MAP kinase activity [GO:0043407] (60 genes, 79 annotations)
                                                                                                        is-ainactivation of MAPK activity +
                                                                                                        is-anegative regulation of JUN kinase activity
                                                                                                is-anegative regulation of myosin light chain kinase activity
                                                                                                is-anegative regulation of Rho-dependent protein serine/threonine kinase activity


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-anegative regulation of biological process
                                        is-anegative regulation of metabolic process
                                                is-anegative regulation of cellular metabolic process
                                                        is-anegative regulation of phosphorus metabolic process
                                                                is-anegative regulation of phosphate metabolic process
                                                                        is-anegative regulation of phosphorylation
                                                                                is-anegative regulation of MAPK cascade
                                                                                        is-ainactivation of MAPKK activity
                                                                                        is-ainactivation of MAPKKK activity
                                                                                        is-anegative regulation of ERK1 and ERK2 cascade
                                                                                        is-anegative regulation of ERK5 cascade
                                                                                        is-anegative regulation of MAP kinase activity [GO:0043407] (60 genes, 79 annotations)
                                                                                                is-ainactivation of MAPK activity +
                                                                                                is-anegative regulation of JUN kinase activity
                                                                                        is-anegative regulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-anegative regulation of biological process
                                        is-anegative regulation of metabolic process
                                                is-anegative regulation of cellular metabolic process
                                                        is-anegative regulation of phosphorus metabolic process
                                                                is-anegative regulation of phosphate metabolic process
                                                                        is-anegative regulation of phosphorylation
                                                                                is-anegative regulation of protein phosphorylation
                                                                                        is-anegative regulation of protein kinase activity
                                                                                                is-anegative regulation of protein serine/threonine kinase activity
                                                                                                        is-ainactivation of MAPKKK activity
                                                                                                        is-anegative regulation of cAMP-dependent protein kinase activity
                                                                                                        is-anegative regulation of cyclin-dependent protein serine/threonine kinase activity +
                                                                                                        is-anegative regulation of MAP kinase activity [GO:0043407] (60 genes, 79 annotations)
                                                                                                                is-ainactivation of MAPK activity +
                                                                                                                is-anegative regulation of JUN kinase activity
                                                                                                        is-anegative regulation of myosin light chain kinase activity
                                                                                                        is-anegative regulation of Rho-dependent protein serine/threonine kinase activity


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-anegative regulation of biological process
                                        is-anegative regulation of metabolic process
                                                is-anegative regulation of macromolecule metabolic process
                                                        is-anegative regulation of protein metabolic process
                                                                is-anegative regulation of cellular protein metabolic process
                                                                        is-anegative regulation of protein modification process
                                                                                is-anegative regulation of protein phosphorylation
                                                                                        is-anegative regulation of protein kinase activity
                                                                                                is-anegative regulation of protein serine/threonine kinase activity
                                                                                                        is-ainactivation of MAPKKK activity
                                                                                                        is-anegative regulation of cAMP-dependent protein kinase activity
                                                                                                        is-anegative regulation of cyclin-dependent protein serine/threonine kinase activity +
                                                                                                        is-anegative regulation of MAP kinase activity [GO:0043407] (60 genes, 79 annotations)
                                                                                                                is-ainactivation of MAPK activity +
                                                                                                                is-anegative regulation of JUN kinase activity
                                                                                                        is-anegative regulation of myosin light chain kinase activity
                                                                                                        is-anegative regulation of Rho-dependent protein serine/threonine kinase activity


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-anegative regulation of biological process
                                        is-anegative regulation of response to stimulus
                                                is-anegative regulation of signal transduction
                                                        is-anegative regulation of intracellular signal transduction
                                                                is-anegative regulation of MAPK cascade
                                                                        is-ainactivation of MAPKK activity
                                                                        is-ainactivation of MAPKKK activity
                                                                        is-anegative regulation of ERK1 and ERK2 cascade
                                                                        is-anegative regulation of ERK5 cascade
                                                                        is-anegative regulation of MAP kinase activity [GO:0043407] (60 genes, 79 annotations)
                                                                                is-ainactivation of MAPK activity +
                                                                                is-anegative regulation of JUN kinase activity
                                                                        is-anegative regulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-anegative regulation of biological process
                                        is-anegative regulation of signaling
                                                is-anegative regulation of signal transduction
                                                        is-anegative regulation of intracellular signal transduction
                                                                is-anegative regulation of MAPK cascade
                                                                        is-ainactivation of MAPKK activity
                                                                        is-ainactivation of MAPKKK activity
                                                                        is-anegative regulation of ERK1 and ERK2 cascade
                                                                        is-anegative regulation of ERK5 cascade
                                                                        is-anegative regulation of MAP kinase activity [GO:0043407] (60 genes, 79 annotations)
                                                                                is-ainactivation of MAPK activity +
                                                                                is-anegative regulation of JUN kinase activity
                                                                        is-anegative regulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-anegative regulation of cellular process
                                                is-anegative regulation of cell communication
                                                        is-anegative regulation of signal transduction
                                                                is-anegative regulation of intracellular signal transduction
                                                                        is-anegative regulation of MAPK cascade
                                                                                is-ainactivation of MAPKK activity
                                                                                is-ainactivation of MAPKKK activity
                                                                                is-anegative regulation of ERK1 and ERK2 cascade
                                                                                is-anegative regulation of ERK5 cascade
                                                                                is-anegative regulation of MAP kinase activity [GO:0043407] (60 genes, 79 annotations)
                                                                                        is-ainactivation of MAPK activity +
                                                                                        is-anegative regulation of JUN kinase activity
                                                                                is-anegative regulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-anegative regulation of cellular process
                                                is-anegative regulation of cellular metabolic process
                                                        is-anegative regulation of cellular protein metabolic process
                                                                is-anegative regulation of protein modification process
                                                                        is-anegative regulation of protein phosphorylation
                                                                                is-anegative regulation of protein kinase activity
                                                                                        is-anegative regulation of protein serine/threonine kinase activity
                                                                                                is-ainactivation of MAPKKK activity
                                                                                                is-anegative regulation of cAMP-dependent protein kinase activity
                                                                                                is-anegative regulation of cyclin-dependent protein serine/threonine kinase activity +
                                                                                                is-anegative regulation of MAP kinase activity [GO:0043407] (60 genes, 79 annotations)
                                                                                                        is-ainactivation of MAPK activity +
                                                                                                        is-anegative regulation of JUN kinase activity
                                                                                                is-anegative regulation of myosin light chain kinase activity
                                                                                                is-anegative regulation of Rho-dependent protein serine/threonine kinase activity


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-anegative regulation of cellular process
                                                is-anegative regulation of cellular metabolic process
                                                        is-anegative regulation of phosphorus metabolic process
                                                                is-anegative regulation of phosphate metabolic process
                                                                        is-anegative regulation of phosphorylation
                                                                                is-anegative regulation of MAPK cascade
                                                                                        is-ainactivation of MAPKK activity
                                                                                        is-ainactivation of MAPKKK activity
                                                                                        is-anegative regulation of ERK1 and ERK2 cascade
                                                                                        is-anegative regulation of ERK5 cascade
                                                                                        is-anegative regulation of MAP kinase activity [GO:0043407] (60 genes, 79 annotations)
                                                                                                is-ainactivation of MAPK activity +
                                                                                                is-anegative regulation of JUN kinase activity
                                                                                        is-anegative regulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-anegative regulation of cellular process
                                                is-anegative regulation of cellular metabolic process
                                                        is-anegative regulation of phosphorus metabolic process
                                                                is-anegative regulation of phosphate metabolic process
                                                                        is-anegative regulation of phosphorylation
                                                                                is-anegative regulation of protein phosphorylation
                                                                                        is-anegative regulation of protein kinase activity
                                                                                                is-anegative regulation of protein serine/threonine kinase activity
                                                                                                        is-ainactivation of MAPKKK activity
                                                                                                        is-anegative regulation of cAMP-dependent protein kinase activity
                                                                                                        is-anegative regulation of cyclin-dependent protein serine/threonine kinase activity +
                                                                                                        is-anegative regulation of MAP kinase activity [GO:0043407] (60 genes, 79 annotations)
                                                                                                                is-ainactivation of MAPK activity +
                                                                                                                is-anegative regulation of JUN kinase activity
                                                                                                        is-anegative regulation of myosin light chain kinase activity
                                                                                                        is-anegative regulation of Rho-dependent protein serine/threonine kinase activity


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-aregulation of cell communication
                                                is-anegative regulation of cell communication
                                                        is-anegative regulation of signal transduction
                                                                is-anegative regulation of intracellular signal transduction
                                                                        is-anegative regulation of MAPK cascade
                                                                                is-ainactivation of MAPKK activity
                                                                                is-ainactivation of MAPKKK activity
                                                                                is-anegative regulation of ERK1 and ERK2 cascade
                                                                                is-anegative regulation of ERK5 cascade
                                                                                is-anegative regulation of MAP kinase activity [GO:0043407] (60 genes, 79 annotations)
                                                                                        is-ainactivation of MAPK activity +
                                                                                        is-anegative regulation of JUN kinase activity
                                                                                is-anegative regulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-aregulation of cell communication
                                                is-aregulation of signal transduction
                                                        is-anegative regulation of signal transduction
                                                                is-anegative regulation of intracellular signal transduction
                                                                        is-anegative regulation of MAPK cascade
                                                                                is-ainactivation of MAPKK activity
                                                                                is-ainactivation of MAPKKK activity
                                                                                is-anegative regulation of ERK1 and ERK2 cascade
                                                                                is-anegative regulation of ERK5 cascade
                                                                                is-anegative regulation of MAP kinase activity [GO:0043407] (60 genes, 79 annotations)
                                                                                        is-ainactivation of MAPK activity +
                                                                                        is-anegative regulation of JUN kinase activity
                                                                                is-anegative regulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-aregulation of cell communication
                                                is-aregulation of signal transduction
                                                        is-aregulation of intracellular signal transduction
                                                                is-anegative regulation of intracellular signal transduction
                                                                        is-anegative regulation of MAPK cascade
                                                                                is-ainactivation of MAPKK activity
                                                                                is-ainactivation of MAPKKK activity
                                                                                is-anegative regulation of ERK1 and ERK2 cascade
                                                                                is-anegative regulation of ERK5 cascade
                                                                                is-anegative regulation of MAP kinase activity [GO:0043407] (60 genes, 79 annotations)
                                                                                        is-ainactivation of MAPK activity +
                                                                                        is-anegative regulation of JUN kinase activity
                                                                                is-anegative regulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-aregulation of cell communication
                                                is-aregulation of signal transduction
                                                        is-aregulation of intracellular signal transduction
                                                                is-aregulation of MAPK cascade
                                                                        is-anegative regulation of MAPK cascade
                                                                                is-ainactivation of MAPKK activity
                                                                                is-ainactivation of MAPKKK activity
                                                                                is-anegative regulation of ERK1 and ERK2 cascade
                                                                                is-anegative regulation of ERK5 cascade
                                                                                is-anegative regulation of MAP kinase activity [GO:0043407] (60 genes, 79 annotations)
                                                                                        is-ainactivation of MAPK activity +
                                                                                        is-anegative regulation of JUN kinase activity
                                                                                is-anegative regulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-aregulation of cell communication
                                                is-aregulation of signal transduction
                                                        is-aregulation of intracellular signal transduction
                                                                is-aregulation of MAPK cascade
                                                                        is-aregulation of MAP kinase activity
                                                                                is-anegative regulation of MAP kinase activity [GO:0043407] (60 genes, 79 annotations)
                                                                                        is-ainactivation of MAPK activity +
                                                                                        is-anegative regulation of JUN kinase activity
                                                                                is-apositive regulation of MAP kinase activity +
                                                                                is-aregulation of JUN kinase activity +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-aregulation of cellular metabolic process
                                                is-anegative regulation of cellular metabolic process
                                                        is-anegative regulation of cellular protein metabolic process
                                                                is-anegative regulation of protein modification process
                                                                        is-anegative regulation of protein phosphorylation
                                                                                is-anegative regulation of protein kinase activity
                                                                                        is-anegative regulation of protein serine/threonine kinase activity
                                                                                                is-ainactivation of MAPKKK activity
                                                                                                is-anegative regulation of cAMP-dependent protein kinase activity
                                                                                                is-anegative regulation of cyclin-dependent protein serine/threonine kinase activity +
                                                                                                is-anegative regulation of MAP kinase activity [GO:0043407] (60 genes, 79 annotations)
                                                                                                        is-ainactivation of MAPK activity +
                                                                                                        is-anegative regulation of JUN kinase activity
                                                                                                is-anegative regulation of myosin light chain kinase activity
                                                                                                is-anegative regulation of Rho-dependent protein serine/threonine kinase activity


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-aregulation of cellular metabolic process
                                                is-anegative regulation of cellular metabolic process
                                                        is-anegative regulation of phosphorus metabolic process
                                                                is-anegative regulation of phosphate metabolic process
                                                                        is-anegative regulation of phosphorylation
                                                                                is-anegative regulation of MAPK cascade
                                                                                        is-ainactivation of MAPKK activity
                                                                                        is-ainactivation of MAPKKK activity
                                                                                        is-anegative regulation of ERK1 and ERK2 cascade
                                                                                        is-anegative regulation of ERK5 cascade
                                                                                        is-anegative regulation of MAP kinase activity [GO:0043407] (60 genes, 79 annotations)
                                                                                                is-ainactivation of MAPK activity +
                                                                                                is-anegative regulation of JUN kinase activity
                                                                                        is-anegative regulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-aregulation of cellular metabolic process
                                                is-anegative regulation of cellular metabolic process
                                                        is-anegative regulation of phosphorus metabolic process
                                                                is-anegative regulation of phosphate metabolic process
                                                                        is-anegative regulation of phosphorylation
                                                                                is-anegative regulation of protein phosphorylation
                                                                                        is-anegative regulation of protein kinase activity
                                                                                                is-anegative regulation of protein serine/threonine kinase activity
                                                                                                        is-ainactivation of MAPKKK activity
                                                                                                        is-anegative regulation of cAMP-dependent protein kinase activity
                                                                                                        is-anegative regulation of cyclin-dependent protein serine/threonine kinase activity +
                                                                                                        is-anegative regulation of MAP kinase activity [GO:0043407] (60 genes, 79 annotations)
                                                                                                                is-ainactivation of MAPK activity +
                                                                                                                is-anegative regulation of JUN kinase activity
                                                                                                        is-anegative regulation of myosin light chain kinase activity
                                                                                                        is-anegative regulation of Rho-dependent protein serine/threonine kinase activity


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-aregulation of cellular metabolic process
                                                is-aregulation of cellular protein metabolic process
                                                        is-anegative regulation of cellular protein metabolic process
                                                                is-anegative regulation of protein modification process
                                                                        is-anegative regulation of protein phosphorylation
                                                                                is-anegative regulation of protein kinase activity
                                                                                        is-anegative regulation of protein serine/threonine kinase activity
                                                                                                is-ainactivation of MAPKKK activity
                                                                                                is-anegative regulation of cAMP-dependent protein kinase activity
                                                                                                is-anegative regulation of cyclin-dependent protein serine/threonine kinase activity +
                                                                                                is-anegative regulation of MAP kinase activity [GO:0043407] (60 genes, 79 annotations)
                                                                                                        is-ainactivation of MAPK activity +
                                                                                                        is-anegative regulation of JUN kinase activity
                                                                                                is-anegative regulation of myosin light chain kinase activity
                                                                                                is-anegative regulation of Rho-dependent protein serine/threonine kinase activity


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-aregulation of cellular metabolic process
                                                is-aregulation of cellular protein metabolic process
                                                        is-aregulation of protein modification process
                                                                is-anegative regulation of protein modification process
                                                                        is-anegative regulation of protein phosphorylation
                                                                                is-anegative regulation of protein kinase activity
                                                                                        is-anegative regulation of protein serine/threonine kinase activity
                                                                                                is-ainactivation of MAPKKK activity
                                                                                                is-anegative regulation of cAMP-dependent protein kinase activity
                                                                                                is-anegative regulation of cyclin-dependent protein serine/threonine kinase activity +
                                                                                                is-anegative regulation of MAP kinase activity [GO:0043407] (60 genes, 79 annotations)
                                                                                                        is-ainactivation of MAPK activity +
                                                                                                        is-anegative regulation of JUN kinase activity
                                                                                                is-anegative regulation of myosin light chain kinase activity
                                                                                                is-anegative regulation of Rho-dependent protein serine/threonine kinase activity


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-aregulation of cellular metabolic process
                                                is-aregulation of cellular protein metabolic process
                                                        is-aregulation of protein modification process
                                                                is-aregulation of protein phosphorylation
                                                                        is-anegative regulation of protein phosphorylation
                                                                                is-anegative regulation of protein kinase activity
                                                                                        is-anegative regulation of protein serine/threonine kinase activity
                                                                                                is-ainactivation of MAPKKK activity
                                                                                                is-anegative regulation of cAMP-dependent protein kinase activity
                                                                                                is-anegative regulation of cyclin-dependent protein serine/threonine kinase activity +
                                                                                                is-anegative regulation of MAP kinase activity [GO:0043407] (60 genes, 79 annotations)
                                                                                                        is-ainactivation of MAPK activity +
                                                                                                        is-anegative regulation of JUN kinase activity
                                                                                                is-anegative regulation of myosin light chain kinase activity
                                                                                                is-anegative regulation of Rho-dependent protein serine/threonine kinase activity


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-aregulation of cellular metabolic process
                                                is-aregulation of cellular protein metabolic process
                                                        is-aregulation of protein modification process
                                                                is-aregulation of protein phosphorylation
                                                                        is-aregulation of protein kinase activity
                                                                                is-anegative regulation of protein kinase activity
                                                                                        is-anegative regulation of protein serine/threonine kinase activity
                                                                                                is-ainactivation of MAPKKK activity
                                                                                                is-anegative regulation of cAMP-dependent protein kinase activity
                                                                                                is-anegative regulation of cyclin-dependent protein serine/threonine kinase activity +
                                                                                                is-anegative regulation of MAP kinase activity [GO:0043407] (60 genes, 79 annotations)
                                                                                                        is-ainactivation of MAPK activity +
                                                                                                        is-anegative regulation of JUN kinase activity
                                                                                                is-anegative regulation of myosin light chain kinase activity
                                                                                                is-anegative regulation of Rho-dependent protein serine/threonine kinase activity


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-aregulation of cellular metabolic process
                                                is-aregulation of cellular protein metabolic process
                                                        is-aregulation of protein modification process
                                                                is-aregulation of protein phosphorylation
                                                                        is-aregulation of protein kinase activity
                                                                                is-aregulation of protein serine/threonine kinase activity
                                                                                        is-anegative regulation of protein serine/threonine kinase activity
                                                                                                is-ainactivation of MAPKKK activity
                                                                                                is-anegative regulation of cAMP-dependent protein kinase activity
                                                                                                is-anegative regulation of cyclin-dependent protein serine/threonine kinase activity +
                                                                                                is-anegative regulation of MAP kinase activity [GO:0043407] (60 genes, 79 annotations)
                                                                                                        is-ainactivation of MAPK activity +
                                                                                                        is-anegative regulation of JUN kinase activity
                                                                                                is-anegative regulation of myosin light chain kinase activity
                                                                                                is-anegative regulation of Rho-dependent protein serine/threonine kinase activity


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-aregulation of cellular metabolic process
                                                is-aregulation of cellular protein metabolic process
                                                        is-aregulation of protein modification process
                                                                is-aregulation of protein phosphorylation
                                                                        is-aregulation of protein kinase activity
                                                                                is-aregulation of protein serine/threonine kinase activity
                                                                                        is-aregulation of MAP kinase activity
                                                                                                is-anegative regulation of MAP kinase activity [GO:0043407] (60 genes, 79 annotations)
                                                                                                        is-ainactivation of MAPK activity +
                                                                                                        is-anegative regulation of JUN kinase activity
                                                                                                is-apositive regulation of MAP kinase activity +
                                                                                                is-aregulation of JUN kinase activity +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-aregulation of cellular metabolic process
                                                is-aregulation of phosphorus metabolic process
                                                        is-anegative regulation of phosphorus metabolic process
                                                                is-anegative regulation of phosphate metabolic process
                                                                        is-anegative regulation of phosphorylation
                                                                                is-anegative regulation of MAPK cascade
                                                                                        is-ainactivation of MAPKK activity
                                                                                        is-ainactivation of MAPKKK activity
                                                                                        is-anegative regulation of ERK1 and ERK2 cascade
                                                                                        is-anegative regulation of ERK5 cascade
                                                                                        is-anegative regulation of MAP kinase activity [GO:0043407] (60 genes, 79 annotations)
                                                                                                is-ainactivation of MAPK activity +
                                                                                                is-anegative regulation of JUN kinase activity
                                                                                        is-anegative regulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-aregulation of cellular metabolic process
                                                is-aregulation of phosphorus metabolic process
                                                        is-anegative regulation of phosphorus metabolic process
                                                                is-anegative regulation of phosphate metabolic process
                                                                        is-anegative regulation of phosphorylation
                                                                                is-anegative regulation of protein phosphorylation
                                                                                        is-anegative regulation of protein kinase activity
                                                                                                is-anegative regulation of protein serine/threonine kinase activity
                                                                                                        is-ainactivation of MAPKKK activity
                                                                                                        is-anegative regulation of cAMP-dependent protein kinase activity
                                                                                                        is-anegative regulation of cyclin-dependent protein serine/threonine kinase activity +
                                                                                                        is-anegative regulation of MAP kinase activity [GO:0043407] (60 genes, 79 annotations)
                                                                                                                is-ainactivation of MAPK activity +
                                                                                                                is-anegative regulation of JUN kinase activity
                                                                                                        is-anegative regulation of myosin light chain kinase activity
                                                                                                        is-anegative regulation of Rho-dependent protein serine/threonine kinase activity


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-aregulation of cellular metabolic process
                                                is-aregulation of phosphorus metabolic process
                                                        is-aregulation of phosphate metabolic process
                                                                is-anegative regulation of phosphate metabolic process
                                                                        is-anegative regulation of phosphorylation
                                                                                is-anegative regulation of MAPK cascade
                                                                                        is-ainactivation of MAPKK activity
                                                                                        is-ainactivation of MAPKKK activity
                                                                                        is-anegative regulation of ERK1 and ERK2 cascade
                                                                                        is-anegative regulation of ERK5 cascade
                                                                                        is-anegative regulation of MAP kinase activity [GO:0043407] (60 genes, 79 annotations)
                                                                                                is-ainactivation of MAPK activity +
                                                                                                is-anegative regulation of JUN kinase activity
                                                                                        is-anegative regulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-aregulation of cellular metabolic process
                                                is-aregulation of phosphorus metabolic process
                                                        is-aregulation of phosphate metabolic process
                                                                is-anegative regulation of phosphate metabolic process
                                                                        is-anegative regulation of phosphorylation
                                                                                is-anegative regulation of protein phosphorylation
                                                                                        is-anegative regulation of protein kinase activity
                                                                                                is-anegative regulation of protein serine/threonine kinase activity
                                                                                                        is-ainactivation of MAPKKK activity
                                                                                                        is-anegative regulation of cAMP-dependent protein kinase activity
                                                                                                        is-anegative regulation of cyclin-dependent protein serine/threonine kinase activity +
                                                                                                        is-anegative regulation of MAP kinase activity [GO:0043407] (60 genes, 79 annotations)
                                                                                                                is-ainactivation of MAPK activity +
                                                                                                                is-anegative regulation of JUN kinase activity
                                                                                                        is-anegative regulation of myosin light chain kinase activity
                                                                                                        is-anegative regulation of Rho-dependent protein serine/threonine kinase activity


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-aregulation of cellular metabolic process
                                                is-aregulation of phosphorus metabolic process
                                                        is-aregulation of phosphate metabolic process
                                                                is-aregulation of phosphorylation
                                                                        is-anegative regulation of phosphorylation
                                                                                is-anegative regulation of MAPK cascade
                                                                                        is-ainactivation of MAPKK activity
                                                                                        is-ainactivation of MAPKKK activity
                                                                                        is-anegative regulation of ERK1 and ERK2 cascade
                                                                                        is-anegative regulation of ERK5 cascade
                                                                                        is-anegative regulation of MAP kinase activity [GO:0043407] (60 genes, 79 annotations)
                                                                                                is-ainactivation of MAPK activity +
                                                                                                is-anegative regulation of JUN kinase activity
                                                                                        is-anegative regulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-aregulation of cellular metabolic process
                                                is-aregulation of phosphorus metabolic process
                                                        is-aregulation of phosphate metabolic process
                                                                is-aregulation of phosphorylation
                                                                        is-anegative regulation of phosphorylation
                                                                                is-anegative regulation of protein phosphorylation
                                                                                        is-anegative regulation of protein kinase activity
                                                                                                is-anegative regulation of protein serine/threonine kinase activity
                                                                                                        is-ainactivation of MAPKKK activity
                                                                                                        is-anegative regulation of cAMP-dependent protein kinase activity
                                                                                                        is-anegative regulation of cyclin-dependent protein serine/threonine kinase activity +
                                                                                                        is-anegative regulation of MAP kinase activity [GO:0043407] (60 genes, 79 annotations)
                                                                                                                is-ainactivation of MAPK activity +
                                                                                                                is-anegative regulation of JUN kinase activity
                                                                                                        is-anegative regulation of myosin light chain kinase activity
                                                                                                        is-anegative regulation of Rho-dependent protein serine/threonine kinase activity


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-aregulation of cellular metabolic process
                                                is-aregulation of phosphorus metabolic process
                                                        is-aregulation of phosphate metabolic process
                                                                is-aregulation of phosphorylation
                                                                        is-aregulation of kinase activity
                                                                                is-anegative regulation of kinase activity
                                                                                        is-anegative regulation of protein kinase activity
                                                                                                is-anegative regulation of protein serine/threonine kinase activity
                                                                                                        is-ainactivation of MAPKKK activity
                                                                                                        is-anegative regulation of cAMP-dependent protein kinase activity
                                                                                                        is-anegative regulation of cyclin-dependent protein serine/threonine kinase activity +
                                                                                                        is-anegative regulation of MAP kinase activity [GO:0043407] (60 genes, 79 annotations)
                                                                                                                is-ainactivation of MAPK activity +
                                                                                                                is-anegative regulation of JUN kinase activity
                                                                                                        is-anegative regulation of myosin light chain kinase activity
                                                                                                        is-anegative regulation of Rho-dependent protein serine/threonine kinase activity


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-aregulation of cellular metabolic process
                                                is-aregulation of phosphorus metabolic process
                                                        is-aregulation of phosphate metabolic process
                                                                is-aregulation of phosphorylation
                                                                        is-aregulation of kinase activity
                                                                                is-aregulation of protein kinase activity
                                                                                        is-anegative regulation of protein kinase activity
                                                                                                is-anegative regulation of protein serine/threonine kinase activity
                                                                                                        is-ainactivation of MAPKKK activity
                                                                                                        is-anegative regulation of cAMP-dependent protein kinase activity
                                                                                                        is-anegative regulation of cyclin-dependent protein serine/threonine kinase activity +
                                                                                                        is-anegative regulation of MAP kinase activity [GO:0043407] (60 genes, 79 annotations)
                                                                                                                is-ainactivation of MAPK activity +
                                                                                                                is-anegative regulation of JUN kinase activity
                                                                                                        is-anegative regulation of myosin light chain kinase activity
                                                                                                        is-anegative regulation of Rho-dependent protein serine/threonine kinase activity


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-aregulation of cellular metabolic process
                                                is-aregulation of phosphorus metabolic process
                                                        is-aregulation of phosphate metabolic process
                                                                is-aregulation of phosphorylation
                                                                        is-aregulation of kinase activity
                                                                                is-aregulation of protein kinase activity
                                                                                        is-aregulation of protein serine/threonine kinase activity
                                                                                                is-anegative regulation of protein serine/threonine kinase activity
                                                                                                        is-ainactivation of MAPKKK activity
                                                                                                        is-anegative regulation of cAMP-dependent protein kinase activity
                                                                                                        is-anegative regulation of cyclin-dependent protein serine/threonine kinase activity +
                                                                                                        is-anegative regulation of MAP kinase activity [GO:0043407] (60 genes, 79 annotations)
                                                                                                                is-ainactivation of MAPK activity +
                                                                                                                is-anegative regulation of JUN kinase activity
                                                                                                        is-anegative regulation of myosin light chain kinase activity
                                                                                                        is-anegative regulation of Rho-dependent protein serine/threonine kinase activity


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-aregulation of cellular metabolic process
                                                is-aregulation of phosphorus metabolic process
                                                        is-aregulation of phosphate metabolic process
                                                                is-aregulation of phosphorylation
                                                                        is-aregulation of kinase activity
                                                                                is-aregulation of protein kinase activity
                                                                                        is-aregulation of protein serine/threonine kinase activity
                                                                                                is-aregulation of MAP kinase activity
                                                                                                        is-anegative regulation of MAP kinase activity [GO:0043407] (60 genes, 79 annotations)
                                                                                                                is-ainactivation of MAPK activity +
                                                                                                                is-anegative regulation of JUN kinase activity
                                                                                                        is-apositive regulation of MAP kinase activity +
                                                                                                        is-aregulation of JUN kinase activity +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-aregulation of cellular metabolic process
                                                is-aregulation of phosphorus metabolic process
                                                        is-aregulation of phosphate metabolic process
                                                                is-aregulation of phosphorylation
                                                                        is-aregulation of MAPK cascade
                                                                                is-anegative regulation of MAPK cascade
                                                                                        is-ainactivation of MAPKK activity
                                                                                        is-ainactivation of MAPKKK activity
                                                                                        is-anegative regulation of ERK1 and ERK2 cascade
                                                                                        is-anegative regulation of ERK5 cascade
                                                                                        is-anegative regulation of MAP kinase activity [GO:0043407] (60 genes, 79 annotations)
                                                                                                is-ainactivation of MAPK activity +
                                                                                                is-anegative regulation of JUN kinase activity
                                                                                        is-anegative regulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-aregulation of cellular metabolic process
                                                is-aregulation of phosphorus metabolic process
                                                        is-aregulation of phosphate metabolic process
                                                                is-aregulation of phosphorylation
                                                                        is-aregulation of MAPK cascade
                                                                                is-aregulation of MAP kinase activity
                                                                                        is-anegative regulation of MAP kinase activity [GO:0043407] (60 genes, 79 annotations)
                                                                                                is-ainactivation of MAPK activity +
                                                                                                is-anegative regulation of JUN kinase activity
                                                                                        is-apositive regulation of MAP kinase activity +
                                                                                        is-aregulation of JUN kinase activity +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-aregulation of cellular metabolic process
                                                is-aregulation of phosphorus metabolic process
                                                        is-aregulation of phosphate metabolic process
                                                                is-aregulation of phosphorylation
                                                                        is-aregulation of protein phosphorylation
                                                                                is-anegative regulation of protein phosphorylation
                                                                                        is-anegative regulation of protein kinase activity
                                                                                                is-anegative regulation of protein serine/threonine kinase activity
                                                                                                        is-ainactivation of MAPKKK activity
                                                                                                        is-anegative regulation of cAMP-dependent protein kinase activity
                                                                                                        is-anegative regulation of cyclin-dependent protein serine/threonine kinase activity +
                                                                                                        is-anegative regulation of MAP kinase activity [GO:0043407] (60 genes, 79 annotations)
                                                                                                                is-ainactivation of MAPK activity +
                                                                                                                is-anegative regulation of JUN kinase activity
                                                                                                        is-anegative regulation of myosin light chain kinase activity
                                                                                                        is-anegative regulation of Rho-dependent protein serine/threonine kinase activity


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-aregulation of cellular metabolic process
                                                is-aregulation of phosphorus metabolic process
                                                        is-aregulation of phosphate metabolic process
                                                                is-aregulation of phosphorylation
                                                                        is-aregulation of protein phosphorylation
                                                                                is-aregulation of protein kinase activity
                                                                                        is-anegative regulation of protein kinase activity
                                                                                                is-anegative regulation of protein serine/threonine kinase activity
                                                                                                        is-ainactivation of MAPKKK activity
                                                                                                        is-anegative regulation of cAMP-dependent protein kinase activity
                                                                                                        is-anegative regulation of cyclin-dependent protein serine/threonine kinase activity +
                                                                                                        is-anegative regulation of MAP kinase activity [GO:0043407] (60 genes, 79 annotations)
                                                                                                                is-ainactivation of MAPK activity +
                                                                                                                is-anegative regulation of JUN kinase activity
                                                                                                        is-anegative regulation of myosin light chain kinase activity
                                                                                                        is-anegative regulation of Rho-dependent protein serine/threonine kinase activity


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-aregulation of cellular metabolic process
                                                is-aregulation of phosphorus metabolic process
                                                        is-aregulation of phosphate metabolic process
                                                                is-aregulation of phosphorylation
                                                                        is-aregulation of protein phosphorylation
                                                                                is-aregulation of protein kinase activity
                                                                                        is-aregulation of protein serine/threonine kinase activity
                                                                                                is-anegative regulation of protein serine/threonine kinase activity
                                                                                                        is-ainactivation of MAPKKK activity
                                                                                                        is-anegative regulation of cAMP-dependent protein kinase activity
                                                                                                        is-anegative regulation of cyclin-dependent protein serine/threonine kinase activity +
                                                                                                        is-anegative regulation of MAP kinase activity [GO:0043407] (60 genes, 79 annotations)
                                                                                                                is-ainactivation of MAPK activity +
                                                                                                                is-anegative regulation of JUN kinase activity
                                                                                                        is-anegative regulation of myosin light chain kinase activity
                                                                                                        is-anegative regulation of Rho-dependent protein serine/threonine kinase activity


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-aregulation of cellular metabolic process
                                                is-aregulation of phosphorus metabolic process
                                                        is-aregulation of phosphate metabolic process
                                                                is-aregulation of phosphorylation
                                                                        is-aregulation of protein phosphorylation
                                                                                is-aregulation of protein kinase activity
                                                                                        is-aregulation of protein serine/threonine kinase activity
                                                                                                is-aregulation of MAP kinase activity
                                                                                                        is-anegative regulation of MAP kinase activity [GO:0043407] (60 genes, 79 annotations)
                                                                                                                is-ainactivation of MAPK activity +
                                                                                                                is-anegative regulation of JUN kinase activity
                                                                                                        is-apositive regulation of MAP kinase activity +
                                                                                                        is-aregulation of JUN kinase activity +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-asignal transduction
                                                is-aintracellular signal transduction
                                                        is-aMAPK cascade
                                                                negatively-regulatesnegative regulation of MAPK cascade
                                                                        is-ainactivation of MAPKK activity
                                                                        is-ainactivation of MAPKKK activity
                                                                        is-anegative regulation of ERK1 and ERK2 cascade
                                                                        is-anegative regulation of ERK5 cascade
                                                                        is-anegative regulation of MAP kinase activity [GO:0043407] (60 genes, 79 annotations)
                                                                                is-ainactivation of MAPK activity +
                                                                                is-anegative regulation of JUN kinase activity
                                                                        is-anegative regulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-asignal transduction
                                                is-aintracellular signal transduction
                                                        is-aMAPK cascade
                                                                regulatesregulation of MAPK cascade
                                                                        is-anegative regulation of MAPK cascade
                                                                                is-ainactivation of MAPKK activity
                                                                                is-ainactivation of MAPKKK activity
                                                                                is-anegative regulation of ERK1 and ERK2 cascade
                                                                                is-anegative regulation of ERK5 cascade
                                                                                is-anegative regulation of MAP kinase activity [GO:0043407] (60 genes, 79 annotations)
                                                                                        is-ainactivation of MAPK activity +
                                                                                        is-anegative regulation of JUN kinase activity
                                                                                is-anegative regulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-asignal transduction
                                                is-aintracellular signal transduction
                                                        is-aMAPK cascade
                                                                regulatesregulation of MAPK cascade
                                                                        is-aregulation of MAP kinase activity
                                                                                is-anegative regulation of MAP kinase activity [GO:0043407] (60 genes, 79 annotations)
                                                                                        is-ainactivation of MAPK activity +
                                                                                        is-anegative regulation of JUN kinase activity
                                                                                is-apositive regulation of MAP kinase activity +
                                                                                is-aregulation of JUN kinase activity +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-asignal transduction
                                                is-aintracellular signal transduction
                                                        negatively-regulatesnegative regulation of intracellular signal transduction
                                                                is-anegative regulation of MAPK cascade
                                                                        is-ainactivation of MAPKK activity
                                                                        is-ainactivation of MAPKKK activity
                                                                        is-anegative regulation of ERK1 and ERK2 cascade
                                                                        is-anegative regulation of ERK5 cascade
                                                                        is-anegative regulation of MAP kinase activity [GO:0043407] (60 genes, 79 annotations)
                                                                                is-ainactivation of MAPK activity +
                                                                                is-anegative regulation of JUN kinase activity
                                                                        is-anegative regulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-asignal transduction
                                                is-aintracellular signal transduction
                                                        regulatesregulation of intracellular signal transduction
                                                                is-anegative regulation of intracellular signal transduction
                                                                        is-anegative regulation of MAPK cascade
                                                                                is-ainactivation of MAPKK activity
                                                                                is-ainactivation of MAPKKK activity
                                                                                is-anegative regulation of ERK1 and ERK2 cascade
                                                                                is-anegative regulation of ERK5 cascade
                                                                                is-anegative regulation of MAP kinase activity [GO:0043407] (60 genes, 79 annotations)
                                                                                        is-ainactivation of MAPK activity +
                                                                                        is-anegative regulation of JUN kinase activity
                                                                                is-anegative regulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-asignal transduction
                                                is-aintracellular signal transduction
                                                        regulatesregulation of intracellular signal transduction
                                                                is-aregulation of MAPK cascade
                                                                        is-anegative regulation of MAPK cascade
                                                                                is-ainactivation of MAPKK activity
                                                                                is-ainactivation of MAPKKK activity
                                                                                is-anegative regulation of ERK1 and ERK2 cascade
                                                                                is-anegative regulation of ERK5 cascade
                                                                                is-anegative regulation of MAP kinase activity [GO:0043407] (60 genes, 79 annotations)
                                                                                        is-ainactivation of MAPK activity +
                                                                                        is-anegative regulation of JUN kinase activity
                                                                                is-anegative regulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-asignal transduction
                                                is-aintracellular signal transduction
                                                        regulatesregulation of intracellular signal transduction
                                                                is-aregulation of MAPK cascade
                                                                        is-aregulation of MAP kinase activity
                                                                                is-anegative regulation of MAP kinase activity [GO:0043407] (60 genes, 79 annotations)
                                                                                        is-ainactivation of MAPK activity +
                                                                                        is-anegative regulation of JUN kinase activity
                                                                                is-apositive regulation of MAP kinase activity +
                                                                                is-aregulation of JUN kinase activity +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-asignal transduction
                                                negatively-regulatesnegative regulation of signal transduction
                                                        is-anegative regulation of intracellular signal transduction
                                                                is-anegative regulation of MAPK cascade
                                                                        is-ainactivation of MAPKK activity
                                                                        is-ainactivation of MAPKKK activity
                                                                        is-anegative regulation of ERK1 and ERK2 cascade
                                                                        is-anegative regulation of ERK5 cascade
                                                                        is-anegative regulation of MAP kinase activity [GO:0043407] (60 genes, 79 annotations)
                                                                                is-ainactivation of MAPK activity +
                                                                                is-anegative regulation of JUN kinase activity
                                                                        is-anegative regulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-asignal transduction
                                                regulatesregulation of signal transduction
                                                        is-anegative regulation of signal transduction
                                                                is-anegative regulation of intracellular signal transduction
                                                                        is-anegative regulation of MAPK cascade
                                                                                is-ainactivation of MAPKK activity
                                                                                is-ainactivation of MAPKKK activity
                                                                                is-anegative regulation of ERK1 and ERK2 cascade
                                                                                is-anegative regulation of ERK5 cascade
                                                                                is-anegative regulation of MAP kinase activity [GO:0043407] (60 genes, 79 annotations)
                                                                                        is-ainactivation of MAPK activity +
                                                                                        is-anegative regulation of JUN kinase activity
                                                                                is-anegative regulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-asignal transduction
                                                regulatesregulation of signal transduction
                                                        is-aregulation of intracellular signal transduction
                                                                is-anegative regulation of intracellular signal transduction
                                                                        is-anegative regulation of MAPK cascade
                                                                                is-ainactivation of MAPKK activity
                                                                                is-ainactivation of MAPKKK activity
                                                                                is-anegative regulation of ERK1 and ERK2 cascade
                                                                                is-anegative regulation of ERK5 cascade
                                                                                is-anegative regulation of MAP kinase activity [GO:0043407] (60 genes, 79 annotations)
                                                                                        is-ainactivation of MAPK activity +
                                                                                        is-anegative regulation of JUN kinase activity
                                                                                is-anegative regulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-asignal transduction
                                                regulatesregulation of signal transduction
                                                        is-aregulation of intracellular signal transduction
                                                                is-aregulation of MAPK cascade
                                                                        is-anegative regulation of MAPK cascade
                                                                                is-ainactivation of MAPKK activity
                                                                                is-ainactivation of MAPKKK activity
                                                                                is-anegative regulation of ERK1 and ERK2 cascade
                                                                                is-anegative regulation of ERK5 cascade
                                                                                is-anegative regulation of MAP kinase activity [GO:0043407] (60 genes, 79 annotations)
                                                                                        is-ainactivation of MAPK activity +
                                                                                        is-anegative regulation of JUN kinase activity
                                                                                is-anegative regulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-asignal transduction
                                                regulatesregulation of signal transduction
                                                        is-aregulation of intracellular signal transduction
                                                                is-aregulation of MAPK cascade
                                                                        is-aregulation of MAP kinase activity
                                                                                is-anegative regulation of MAP kinase activity [GO:0043407] (60 genes, 79 annotations)
                                                                                        is-ainactivation of MAPK activity +
                                                                                        is-anegative regulation of JUN kinase activity
                                                                                is-apositive regulation of MAP kinase activity +
                                                                                is-aregulation of JUN kinase activity +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-asignal transduction
                                                is-asignal transduction by phosphorylation
                                                        is-aMAPK cascade
                                                                negatively-regulatesnegative regulation of MAPK cascade
                                                                        is-ainactivation of MAPKK activity
                                                                        is-ainactivation of MAPKKK activity
                                                                        is-anegative regulation of ERK1 and ERK2 cascade
                                                                        is-anegative regulation of ERK5 cascade
                                                                        is-anegative regulation of MAP kinase activity [GO:0043407] (60 genes, 79 annotations)
                                                                                is-ainactivation of MAPK activity +
                                                                                is-anegative regulation of JUN kinase activity
                                                                        is-anegative regulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-asignal transduction
                                                is-asignal transduction by phosphorylation
                                                        is-aMAPK cascade
                                                                regulatesregulation of MAPK cascade
                                                                        is-anegative regulation of MAPK cascade
                                                                                is-ainactivation of MAPKK activity
                                                                                is-ainactivation of MAPKKK activity
                                                                                is-anegative regulation of ERK1 and ERK2 cascade
                                                                                is-anegative regulation of ERK5 cascade
                                                                                is-anegative regulation of MAP kinase activity [GO:0043407] (60 genes, 79 annotations)
                                                                                        is-ainactivation of MAPK activity +
                                                                                        is-anegative regulation of JUN kinase activity
                                                                                is-anegative regulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-asignal transduction
                                                is-asignal transduction by phosphorylation
                                                        is-aMAPK cascade
                                                                regulatesregulation of MAPK cascade
                                                                        is-aregulation of MAP kinase activity
                                                                                is-anegative regulation of MAP kinase activity [GO:0043407] (60 genes, 79 annotations)
                                                                                        is-ainactivation of MAPK activity +
                                                                                        is-anegative regulation of JUN kinase activity
                                                                                is-apositive regulation of MAP kinase activity +
                                                                                is-aregulation of JUN kinase activity +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of metabolic process
                                        is-anegative regulation of metabolic process
                                                is-anegative regulation of cellular metabolic process
                                                        is-anegative regulation of cellular protein metabolic process
                                                                is-anegative regulation of protein modification process
                                                                        is-anegative regulation of protein phosphorylation
                                                                                is-anegative regulation of protein kinase activity
                                                                                        is-anegative regulation of protein serine/threonine kinase activity
                                                                                                is-ainactivation of MAPKKK activity
                                                                                                is-anegative regulation of cAMP-dependent protein kinase activity
                                                                                                is-anegative regulation of cyclin-dependent protein serine/threonine kinase activity +
                                                                                                is-anegative regulation of MAP kinase activity [GO:0043407] (60 genes, 79 annotations)
                                                                                                        is-ainactivation of MAPK activity +
                                                                                                        is-anegative regulation of JUN kinase activity
                                                                                                is-anegative regulation of myosin light chain kinase activity
                                                                                                is-anegative regulation of Rho-dependent protein serine/threonine kinase activity


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of metabolic process
                                        is-anegative regulation of metabolic process
                                                is-anegative regulation of cellular metabolic process
                                                        is-anegative regulation of phosphorus metabolic process
                                                                is-anegative regulation of phosphate metabolic process
                                                                        is-anegative regulation of phosphorylation
                                                                                is-anegative regulation of MAPK cascade
                                                                                        is-ainactivation of MAPKK activity
                                                                                        is-ainactivation of MAPKKK activity
                                                                                        is-anegative regulation of ERK1 and ERK2 cascade
                                                                                        is-anegative regulation of ERK5 cascade
                                                                                        is-anegative regulation of MAP kinase activity [GO:0043407] (60 genes, 79 annotations)
                                                                                                is-ainactivation of MAPK activity +
                                                                                                is-anegative regulation of JUN kinase activity
                                                                                        is-anegative regulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of metabolic process
                                        is-anegative regulation of metabolic process
                                                is-anegative regulation of cellular metabolic process
                                                        is-anegative regulation of phosphorus metabolic process
                                                                is-anegative regulation of phosphate metabolic process
                                                                        is-anegative regulation of phosphorylation
                                                                                is-anegative regulation of protein phosphorylation
                                                                                        is-anegative regulation of protein kinase activity
                                                                                                is-anegative regulation of protein serine/threonine kinase activity
                                                                                                        is-ainactivation of MAPKKK activity
                                                                                                        is-anegative regulation of cAMP-dependent protein kinase activity
                                                                                                        is-anegative regulation of cyclin-dependent protein serine/threonine kinase activity +
                                                                                                        is-anegative regulation of MAP kinase activity [GO:0043407] (60 genes, 79 annotations)
                                                                                                                is-ainactivation of MAPK activity +
                                                                                                                is-anegative regulation of JUN kinase activity
                                                                                                        is-anegative regulation of myosin light chain kinase activity
                                                                                                        is-anegative regulation of Rho-dependent protein serine/threonine kinase activity


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of metabolic process
                                        is-anegative regulation of metabolic process
                                                is-anegative regulation of macromolecule metabolic process
                                                        is-anegative regulation of protein metabolic process
                                                                is-anegative regulation of cellular protein metabolic process
                                                                        is-anegative regulation of protein modification process
                                                                                is-anegative regulation of protein phosphorylation
                                                                                        is-anegative regulation of protein kinase activity
                                                                                                is-anegative regulation of protein serine/threonine kinase activity
                                                                                                        is-ainactivation of MAPKKK activity
                                                                                                        is-anegative regulation of cAMP-dependent protein kinase activity
                                                                                                        is-anegative regulation of cyclin-dependent protein serine/threonine kinase activity +
                                                                                                        is-anegative regulation of MAP kinase activity [GO:0043407] (60 genes, 79 annotations)
                                                                                                                is-ainactivation of MAPK activity +
                                                                                                                is-anegative regulation of JUN kinase activity
                                                                                                        is-anegative regulation of myosin light chain kinase activity
                                                                                                        is-anegative regulation of Rho-dependent protein serine/threonine kinase activity


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of metabolic process
                                        is-aregulation of catalytic activity
                                                is-anegative regulation of catalytic activity
                                                        is-anegative regulation of transferase activity
                                                                is-anegative regulation of kinase activity
                                                                        is-anegative regulation of protein kinase activity
                                                                                is-anegative regulation of protein serine/threonine kinase activity
                                                                                        is-ainactivation of MAPKKK activity
                                                                                        is-anegative regulation of cAMP-dependent protein kinase activity
                                                                                        is-anegative regulation of cyclin-dependent protein serine/threonine kinase activity +
                                                                                        is-anegative regulation of MAP kinase activity [GO:0043407] (60 genes, 79 annotations)
                                                                                                is-ainactivation of MAPK activity +
                                                                                                is-anegative regulation of JUN kinase activity
                                                                                        is-anegative regulation of myosin light chain kinase activity
                                                                                        is-anegative regulation of Rho-dependent protein serine/threonine kinase activity


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of metabolic process
                                        is-aregulation of catalytic activity
                                                is-aregulation of transferase activity
                                                        is-anegative regulation of transferase activity
                                                                is-anegative regulation of kinase activity
                                                                        is-anegative regulation of protein kinase activity
                                                                                is-anegative regulation of protein serine/threonine kinase activity
                                                                                        is-ainactivation of MAPKKK activity
                                                                                        is-anegative regulation of cAMP-dependent protein kinase activity
                                                                                        is-anegative regulation of cyclin-dependent protein serine/threonine kinase activity +
                                                                                        is-anegative regulation of MAP kinase activity [GO:0043407] (60 genes, 79 annotations)
                                                                                                is-ainactivation of MAPK activity +
                                                                                                is-anegative regulation of JUN kinase activity
                                                                                        is-anegative regulation of myosin light chain kinase activity
                                                                                        is-anegative regulation of Rho-dependent protein serine/threonine kinase activity


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of metabolic process
                                        is-aregulation of catalytic activity
                                                is-aregulation of transferase activity
                                                        is-aregulation of kinase activity
                                                                is-anegative regulation of kinase activity
                                                                        is-anegative regulation of protein kinase activity
                                                                                is-anegative regulation of protein serine/threonine kinase activity
                                                                                        is-ainactivation of MAPKKK activity
                                                                                        is-anegative regulation of cAMP-dependent protein kinase activity
                                                                                        is-anegative regulation of cyclin-dependent protein serine/threonine kinase activity +
                                                                                        is-anegative regulation of MAP kinase activity [GO:0043407] (60 genes, 79 annotations)
                                                                                                is-ainactivation of MAPK activity +
                                                                                                is-anegative regulation of JUN kinase activity
                                                                                        is-anegative regulation of myosin light chain kinase activity
                                                                                        is-anegative regulation of Rho-dependent protein serine/threonine kinase activity


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of metabolic process
                                        is-aregulation of catalytic activity
                                                is-aregulation of transferase activity
                                                        is-aregulation of kinase activity
                                                                is-aregulation of protein kinase activity
                                                                        is-anegative regulation of protein kinase activity
                                                                                is-anegative regulation of protein serine/threonine kinase activity
                                                                                        is-ainactivation of MAPKKK activity
                                                                                        is-anegative regulation of cAMP-dependent protein kinase activity
                                                                                        is-anegative regulation of cyclin-dependent protein serine/threonine kinase activity +
                                                                                        is-anegative regulation of MAP kinase activity [GO:0043407] (60 genes, 79 annotations)
                                                                                                is-ainactivation of MAPK activity +
                                                                                                is-anegative regulation of JUN kinase activity
                                                                                        is-anegative regulation of myosin light chain kinase activity
                                                                                        is-anegative regulation of Rho-dependent protein serine/threonine kinase activity


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of metabolic process
                                        is-aregulation of catalytic activity
                                                is-aregulation of transferase activity
                                                        is-aregulation of kinase activity
                                                                is-aregulation of protein kinase activity
                                                                        is-aregulation of protein serine/threonine kinase activity
                                                                                is-anegative regulation of protein serine/threonine kinase activity
                                                                                        is-ainactivation of MAPKKK activity
                                                                                        is-anegative regulation of cAMP-dependent protein kinase activity
                                                                                        is-anegative regulation of cyclin-dependent protein serine/threonine kinase activity +
                                                                                        is-anegative regulation of MAP kinase activity [GO:0043407] (60 genes, 79 annotations)
                                                                                                is-ainactivation of MAPK activity +
                                                                                                is-anegative regulation of JUN kinase activity
                                                                                        is-anegative regulation of myosin light chain kinase activity
                                                                                        is-anegative regulation of Rho-dependent protein serine/threonine kinase activity


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of metabolic process
                                        is-aregulation of catalytic activity
                                                is-aregulation of transferase activity
                                                        is-aregulation of kinase activity
                                                                is-aregulation of protein kinase activity
                                                                        is-aregulation of protein serine/threonine kinase activity
                                                                                is-aregulation of MAP kinase activity
                                                                                        is-anegative regulation of MAP kinase activity [GO:0043407] (60 genes, 79 annotations)
                                                                                                is-ainactivation of MAPK activity +
                                                                                                is-anegative regulation of JUN kinase activity
                                                                                        is-apositive regulation of MAP kinase activity +
                                                                                        is-aregulation of JUN kinase activity +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of metabolic process
                                        is-aregulation of cellular metabolic process
                                                is-anegative regulation of cellular metabolic process
                                                        is-anegative regulation of cellular protein metabolic process
                                                                is-anegative regulation of protein modification process
                                                                        is-anegative regulation of protein phosphorylation
                                                                                is-anegative regulation of protein kinase activity
                                                                                        is-anegative regulation of protein serine/threonine kinase activity
                                                                                                is-ainactivation of MAPKKK activity
                                                                                                is-anegative regulation of cAMP-dependent protein kinase activity
                                                                                                is-anegative regulation of cyclin-dependent protein serine/threonine kinase activity +
                                                                                                is-anegative regulation of MAP kinase activity [GO:0043407] (60 genes, 79 annotations)
                                                                                                        is-ainactivation of MAPK activity +
                                                                                                        is-anegative regulation of JUN kinase activity
                                                                                                is-anegative regulation of myosin light chain kinase activity
                                                                                                is-anegative regulation of Rho-dependent protein serine/threonine kinase activity


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of metabolic process
                                        is-aregulation of cellular metabolic process
                                                is-anegative regulation of cellular metabolic process
                                                        is-anegative regulation of phosphorus metabolic process
                                                                is-anegative regulation of phosphate metabolic process
                                                                        is-anegative regulation of phosphorylation
                                                                                is-anegative regulation of MAPK cascade
                                                                                        is-ainactivation of MAPKK activity
                                                                                        is-ainactivation of MAPKKK activity
                                                                                        is-anegative regulation of ERK1 and ERK2 cascade
                                                                                        is-anegative regulation of ERK5 cascade
                                                                                        is-anegative regulation of MAP kinase activity [GO:0043407] (60 genes, 79 annotations)
                                                                                                is-ainactivation of MAPK activity +
                                                                                                is-anegative regulation of JUN kinase activity
                                                                                        is-anegative regulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of metabolic process
                                        is-aregulation of cellular metabolic process
                                                is-anegative regulation of cellular metabolic process
                                                        is-anegative regulation of phosphorus metabolic process
                                                                is-anegative regulation of phosphate metabolic process
                                                                        is-anegative regulation of phosphorylation
                                                                                is-anegative regulation of protein phosphorylation
                                                                                        is-anegative regulation of protein kinase activity
                                                                                                is-anegative regulation of protein serine/threonine kinase activity
                                                                                                        is-ainactivation of MAPKKK activity
                                                                                                        is-anegative regulation of cAMP-dependent protein kinase activity
                                                                                                        is-anegative regulation of cyclin-dependent protein serine/threonine kinase activity +
                                                                                                        is-anegative regulation of MAP kinase activity [GO:0043407] (60 genes, 79 annotations)
                                                                                                                is-ainactivation of MAPK activity +
                                                                                                                is-anegative regulation of JUN kinase activity
                                                                                                        is-anegative regulation of myosin light chain kinase activity
                                                                                                        is-anegative regulation of Rho-dependent protein serine/threonine kinase activity


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of metabolic process
                                        is-aregulation of cellular metabolic process
                                                is-aregulation of cellular protein metabolic process
                                                        is-anegative regulation of cellular protein metabolic process
                                                                is-anegative regulation of protein modification process
                                                                        is-anegative regulation of protein phosphorylation
                                                                                is-anegative regulation of protein kinase activity
                                                                                        is-anegative regulation of protein serine/threonine kinase activity
                                                                                                is-ainactivation of MAPKKK activity
                                                                                                is-anegative regulation of cAMP-dependent protein kinase activity
                                                                                                is-anegative regulation of cyclin-dependent protein serine/threonine kinase activity +
                                                                                                is-anegative regulation of MAP kinase activity [GO:0043407] (60 genes, 79 annotations)
                                                                                                        is-ainactivation of MAPK activity +
                                                                                                        is-anegative regulation of JUN kinase activity
                                                                                                is-anegative regulation of myosin light chain kinase activity
                                                                                                is-anegative regulation of Rho-dependent protein serine/threonine kinase activity


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of metabolic process
                                        is-aregulation of cellular metabolic process
                                                is-aregulation of cellular protein metabolic process
                                                        is-aregulation of protein modification process
                                                                is-anegative regulation of protein modification process
                                                                        is-anegative regulation of protein phosphorylation
                                                                                is-anegative regulation of protein kinase activity
                                                                                        is-anegative regulation of protein serine/threonine kinase activity
                                                                                                is-ainactivation of MAPKKK activity
                                                                                                is-anegative regulation of cAMP-dependent protein kinase activity
                                                                                                is-anegative regulation of cyclin-dependent protein serine/threonine kinase activity +
                                                                                                is-anegative regulation of MAP kinase activity [GO:0043407] (60 genes, 79 annotations)
                                                                                                        is-ainactivation of MAPK activity +
                                                                                                        is-anegative regulation of JUN kinase activity
                                                                                                is-anegative regulation of myosin light chain kinase activity
                                                                                                is-anegative regulation of Rho-dependent protein serine/threonine kinase activity


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of metabolic process
                                        is-aregulation of cellular metabolic process
                                                is-aregulation of cellular protein metabolic process
                                                        is-aregulation of protein modification process
                                                                is-aregulation of protein phosphorylation
                                                                        is-anegative regulation of protein phosphorylation
                                                                                is-anegative regulation of protein kinase activity
                                                                                        is-anegative regulation of protein serine/threonine kinase activity
                                                                                                is-ainactivation of MAPKKK activity
                                                                                                is-anegative regulation of cAMP-dependent protein kinase activity
                                                                                                is-anegative regulation of cyclin-dependent protein serine/threonine kinase activity +
                                                                                                is-anegative regulation of MAP kinase activity [GO:0043407] (60 genes, 79 annotations)
                                                                                                        is-ainactivation of MAPK activity +
                                                                                                        is-anegative regulation of JUN kinase activity
                                                                                                is-anegative regulation of myosin light chain kinase activity
                                                                                                is-anegative regulation of Rho-dependent protein serine/threonine kinase activity


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of metabolic process
                                        is-aregulation of cellular metabolic process
                                                is-aregulation of cellular protein metabolic process
                                                        is-aregulation of protein modification process
                                                                is-aregulation of protein phosphorylation
                                                                        is-aregulation of protein kinase activity
                                                                                is-anegative regulation of protein kinase activity
                                                                                        is-anegative regulation of protein serine/threonine kinase activity
                                                                                                is-ainactivation of MAPKKK activity
                                                                                                is-anegative regulation of cAMP-dependent protein kinase activity
                                                                                                is-anegative regulation of cyclin-dependent protein serine/threonine kinase activity +
                                                                                                is-anegative regulation of MAP kinase activity [GO:0043407] (60 genes, 79 annotations)
                                                                                                        is-ainactivation of MAPK activity +
                                                                                                        is-anegative regulation of JUN kinase activity
                                                                                                is-anegative regulation of myosin light chain kinase activity
                                                                                                is-anegative regulation of Rho-dependent protein serine/threonine kinase activity


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of metabolic process
                                        is-aregulation of cellular metabolic process
                                                is-aregulation of cellular protein metabolic process
                                                        is-aregulation of protein modification process
                                                                is-aregulation of protein phosphorylation
                                                                        is-aregulation of protein kinase activity
                                                                                is-aregulation of protein serine/threonine kinase activity
                                                                                        is-anegative regulation of protein serine/threonine kinase activity
                                                                                                is-ainactivation of MAPKKK activity
                                                                                                is-anegative regulation of cAMP-dependent protein kinase activity
                                                                                                is-anegative regulation of cyclin-dependent protein serine/threonine kinase activity +
                                                                                                is-anegative regulation of MAP kinase activity [GO:0043407] (60 genes, 79 annotations)
                                                                                                        is-ainactivation of MAPK activity +
                                                                                                        is-anegative regulation of JUN kinase activity
                                                                                                is-anegative regulation of myosin light chain kinase activity
                                                                                                is-anegative regulation of Rho-dependent protein serine/threonine kinase activity


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of metabolic process
                                        is-aregulation of cellular metabolic process
                                                is-aregulation of cellular protein metabolic process
                                                        is-aregulation of protein modification process
                                                                is-aregulation of protein phosphorylation
                                                                        is-aregulation of protein kinase activity
                                                                                is-aregulation of protein serine/threonine kinase activity
                                                                                        is-aregulation of MAP kinase activity
                                                                                                is-anegative regulation of MAP kinase activity [GO:0043407] (60 genes, 79 annotations)
                                                                                                        is-ainactivation of MAPK activity +
                                                                                                        is-anegative regulation of JUN kinase activity
                                                                                                is-apositive regulation of MAP kinase activity +
                                                                                                is-aregulation of JUN kinase activity +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of metabolic process
                                        is-aregulation of cellular metabolic process
                                                is-aregulation of phosphorus metabolic process
                                                        is-anegative regulation of phosphorus metabolic process
                                                                is-anegative regulation of phosphate metabolic process
                                                                        is-anegative regulation of phosphorylation
                                                                                is-anegative regulation of MAPK cascade
                                                                                        is-ainactivation of MAPKK activity
                                                                                        is-ainactivation of MAPKKK activity
                                                                                        is-anegative regulation of ERK1 and ERK2 cascade
                                                                                        is-anegative regulation of ERK5 cascade
                                                                                        is-anegative regulation of MAP kinase activity [GO:0043407] (60 genes, 79 annotations)
                                                                                                is-ainactivation of MAPK activity +
                                                                                                is-anegative regulation of JUN kinase activity
                                                                                        is-anegative regulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of metabolic process
                                        is-aregulation of cellular metabolic process
                                                is-aregulation of phosphorus metabolic process
                                                        is-anegative regulation of phosphorus metabolic process
                                                                is-anegative regulation of phosphate metabolic process
                                                                        is-anegative regulation of phosphorylation
                                                                                is-anegative regulation of protein phosphorylation
                                                                                        is-anegative regulation of protein kinase activity
                                                                                                is-anegative regulation of protein serine/threonine kinase activity
                                                                                                        is-ainactivation of MAPKKK activity
                                                                                                        is-anegative regulation of cAMP-dependent protein kinase activity
                                                                                                        is-anegative regulation of cyclin-dependent protein serine/threonine kinase activity +
                                                                                                        is-anegative regulation of MAP kinase activity [GO:0043407] (60 genes, 79 annotations)
                                                                                                                is-ainactivation of MAPK activity +
                                                                                                                is-anegative regulation of JUN kinase activity
                                                                                                        is-anegative regulation of myosin light chain kinase activity
                                                                                                        is-anegative regulation of Rho-dependent protein serine/threonine kinase activity


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of metabolic process
                                        is-aregulation of cellular metabolic process
                                                is-aregulation of phosphorus metabolic process
                                                        is-aregulation of phosphate metabolic process
                                                                is-anegative regulation of phosphate metabolic process
                                                                        is-anegative regulation of phosphorylation
                                                                                is-anegative regulation of MAPK cascade
                                                                                        is-ainactivation of MAPKK activity
                                                                                        is-ainactivation of MAPKKK activity
                                                                                        is-anegative regulation of ERK1 and ERK2 cascade
                                                                                        is-anegative regulation of ERK5 cascade
                                                                                        is-anegative regulation of MAP kinase activity [GO:0043407] (60 genes, 79 annotations)
                                                                                                is-ainactivation of MAPK activity +
                                                                                                is-anegative regulation of JUN kinase activity
                                                                                        is-anegative regulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of metabolic process
                                        is-aregulation of cellular metabolic process
                                                is-aregulation of phosphorus metabolic process
                                                        is-aregulation of phosphate metabolic process
                                                                is-anegative regulation of phosphate metabolic process
                                                                        is-anegative regulation of phosphorylation
                                                                                is-anegative regulation of protein phosphorylation
                                                                                        is-anegative regulation of protein kinase activity
                                                                                                is-anegative regulation of protein serine/threonine kinase activity
                                                                                                        is-ainactivation of MAPKKK activity
                                                                                                        is-anegative regulation of cAMP-dependent protein kinase activity
                                                                                                        is-anegative regulation of cyclin-dependent protein serine/threonine kinase activity +
                                                                                                        is-anegative regulation of MAP kinase activity [GO:0043407] (60 genes, 79 annotations)
                                                                                                                is-ainactivation of MAPK activity +
                                                                                                                is-anegative regulation of JUN kinase activity
                                                                                                        is-anegative regulation of myosin light chain kinase activity
                                                                                                        is-anegative regulation of Rho-dependent protein serine/threonine kinase activity


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of metabolic process
                                        is-aregulation of cellular metabolic process
                                                is-aregulation of phosphorus metabolic process
                                                        is-aregulation of phosphate metabolic process
                                                                is-aregulation of phosphorylation
                                                                        is-anegative regulation of phosphorylation
                                                                                is-anegative regulation of MAPK cascade
                                                                                        is-ainactivation of MAPKK activity
                                                                                        is-ainactivation of MAPKKK activity
                                                                                        is-anegative regulation of ERK1 and ERK2 cascade
                                                                                        is-anegative regulation of ERK5 cascade
                                                                                        is-anegative regulation of MAP kinase activity [GO:0043407] (60 genes, 79 annotations)
                                                                                                is-ainactivation of MAPK activity +
                                                                                                is-anegative regulation of JUN kinase activity
                                                                                        is-anegative regulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of metabolic process
                                        is-aregulation of cellular metabolic process
                                                is-aregulation of phosphorus metabolic process
                                                        is-aregulation of phosphate metabolic process
                                                                is-aregulation of phosphorylation
                                                                        is-anegative regulation of phosphorylation
                                                                                is-anegative regulation of protein phosphorylation
                                                                                        is-anegative regulation of protein kinase activity
                                                                                                is-anegative regulation of protein serine/threonine kinase activity
                                                                                                        is-ainactivation of MAPKKK activity
                                                                                                        is-anegative regulation of cAMP-dependent protein kinase activity
                                                                                                        is-anegative regulation of cyclin-dependent protein serine/threonine kinase activity +
                                                                                                        is-anegative regulation of MAP kinase activity [GO:0043407] (60 genes, 79 annotations)
                                                                                                                is-ainactivation of MAPK activity +
                                                                                                                is-anegative regulation of JUN kinase activity
                                                                                                        is-anegative regulation of myosin light chain kinase activity
                                                                                                        is-anegative regulation of Rho-dependent protein serine/threonine kinase activity


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of metabolic process
                                        is-aregulation of cellular metabolic process
                                                is-aregulation of phosphorus metabolic process
                                                        is-aregulation of phosphate metabolic process
                                                                is-aregulation of phosphorylation
                                                                        is-aregulation of kinase activity
                                                                                is-anegative regulation of kinase activity
                                                                                        is-anegative regulation of protein kinase activity
                                                                                                is-anegative regulation of protein serine/threonine kinase activity
                                                                                                        is-ainactivation of MAPKKK activity
                                                                                                        is-anegative regulation of cAMP-dependent protein kinase activity
                                                                                                        is-anegative regulation of cyclin-dependent protein serine/threonine kinase activity +
                                                                                                        is-anegative regulation of MAP kinase activity [GO:0043407] (60 genes, 79 annotations)
                                                                                                                is-ainactivation of MAPK activity +
                                                                                                                is-anegative regulation of JUN kinase activity
                                                                                                        is-anegative regulation of myosin light chain kinase activity
                                                                                                        is-anegative regulation of Rho-dependent protein serine/threonine kinase activity


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of metabolic process
                                        is-aregulation of cellular metabolic process
                                                is-aregulation of phosphorus metabolic process
                                                        is-aregulation of phosphate metabolic process
                                                                is-aregulation of phosphorylation
                                                                        is-aregulation of kinase activity
                                                                                is-aregulation of protein kinase activity
                                                                                        is-anegative regulation of protein kinase activity
                                                                                                is-anegative regulation of protein serine/threonine kinase activity
                                                                                                        is-ainactivation of MAPKKK activity
                                                                                                        is-anegative regulation of cAMP-dependent protein kinase activity
                                                                                                        is-anegative regulation of cyclin-dependent protein serine/threonine kinase activity +
                                                                                                        is-anegative regulation of MAP kinase activity [GO:0043407] (60 genes, 79 annotations)
                                                                                                                is-ainactivation of MAPK activity +
                                                                                                                is-anegative regulation of JUN kinase activity
                                                                                                        is-anegative regulation of myosin light chain kinase activity
                                                                                                        is-anegative regulation of Rho-dependent protein serine/threonine kinase activity


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of metabolic process
                                        is-aregulation of cellular metabolic process
                                                is-aregulation of phosphorus metabolic process
                                                        is-aregulation of phosphate metabolic process
                                                                is-aregulation of phosphorylation
                                                                        is-aregulation of kinase activity
                                                                                is-aregulation of protein kinase activity
                                                                                        is-aregulation of protein serine/threonine kinase activity
                                                                                                is-anegative regulation of protein serine/threonine kinase activity
                                                                                                        is-ainactivation of MAPKKK activity
                                                                                                        is-anegative regulation of cAMP-dependent protein kinase activity
                                                                                                        is-anegative regulation of cyclin-dependent protein serine/threonine kinase activity +
                                                                                                        is-anegative regulation of MAP kinase activity [GO:0043407] (60 genes, 79 annotations)
                                                                                                                is-ainactivation of MAPK activity +
                                                                                                                is-anegative regulation of JUN kinase activity
                                                                                                        is-anegative regulation of myosin light chain kinase activity
                                                                                                        is-anegative regulation of Rho-dependent protein serine/threonine kinase activity


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of metabolic process
                                        is-aregulation of cellular metabolic process
                                                is-aregulation of phosphorus metabolic process
                                                        is-aregulation of phosphate metabolic process
                                                                is-aregulation of phosphorylation
                                                                        is-aregulation of kinase activity
                                                                                is-aregulation of protein kinase activity
                                                                                        is-aregulation of protein serine/threonine kinase activity
                                                                                                is-aregulation of MAP kinase activity
                                                                                                        is-anegative regulation of MAP kinase activity [GO:0043407] (60 genes, 79 annotations)
                                                                                                                is-ainactivation of MAPK activity +
                                                                                                                is-anegative regulation of JUN kinase activity
                                                                                                        is-apositive regulation of MAP kinase activity +
                                                                                                        is-aregulation of JUN kinase activity +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of metabolic process
                                        is-aregulation of cellular metabolic process
                                                is-aregulation of phosphorus metabolic process
                                                        is-aregulation of phosphate metabolic process
                                                                is-aregulation of phosphorylation
                                                                        is-aregulation of MAPK cascade
                                                                                is-anegative regulation of MAPK cascade
                                                                                        is-ainactivation of MAPKK activity
                                                                                        is-ainactivation of MAPKKK activity
                                                                                        is-anegative regulation of ERK1 and ERK2 cascade
                                                                                        is-anegative regulation of ERK5 cascade
                                                                                        is-anegative regulation of MAP kinase activity [GO:0043407] (60 genes, 79 annotations)
                                                                                                is-ainactivation of MAPK activity +
                                                                                                is-anegative regulation of JUN kinase activity
                                                                                        is-anegative regulation of stress-activated MAPK cascade +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of metabolic process
                                        is-aregulation of cellular metabolic process
                                                is-aregulation of phosphorus metabolic process
                                                        is-aregulation of phosphate metabolic process
                                                                is-aregulation of phosphorylation
                                                                        is-aregulation of MAPK cascade
                                                                                is-aregulation of MAP kinase activity
                                                                                        is-anegative regulation of MAP kinase activity [GO:0043407] (60 genes, 79 annotations)
                                                                                                is-ainactivation of MAPK activity +
                                                                                                is-anegative regulation of JUN kinase activity
                                                                                        is-apositive regulation of MAP kinase activity +
                                                                                        is-aregulation of JUN kinase activity +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of metabolic process
                                        is-aregulation of cellular metabolic process
                                                is-aregulation of phosphorus metabolic process
                                                        is-aregulation of phosphate metabolic process
                                                                is-aregulation of phosphorylation
                                                                        is-aregulation of protein phosphorylation
                                                                                is-anegative regulation of protein phosphorylation
                                                                                        is-anegative regulation of protein kinase activity
                                                                                                is-anegative regulation of protein serine/threonine kinase activity
                                                                                                        is-ainactivation of MAPKKK activity
                                                                                                        is-anegative regulation of cAMP-dependent protein kinase activity
                                                                                                        is-anegative regulation of cyclin-dependent protein serine/threonine kinase activity +
                                                                                                        is-anegative regulation of MAP kinase activity [GO:0043407] (60 genes, 79 annotations)
                                                                                                                is-ainactivation of MAPK activity +
                                                                                                                is-anegative regulation of JUN kinase activity
                                                                                                        is-anegative regulation of myosin light chain kinase activity
                                                                                                        is-anegative regulation of Rho-dependent protein serine/threonine kinase activity


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of metabolic process
                                        is-aregulation of cellular metabolic process
                                                is-aregulation of phosphorus metabolic process
                                                        is-aregulation of phosphate metabolic process
                                                                is-aregulation of phosphorylation
                                                                        is-aregulation of protein phosphorylation
                                                                                is-aregulation of protein kinase activity
                                                                                        is-anegative regulation of protein kinase activity
                                                                                                is-anegative regulation of protein serine/threonine kinase activity
                                                                                                        is-ainactivation of MAPKKK activity
                                                                                                        is-anegative regulation of cAMP-dependent protein kinase activity
                                                                                                        is-anegative regulation of cyclin-dependent protein serine/threonine kinase activity +
                                                                                                        is-anegative regulation of MAP kinase activity [GO:0043407] (60 genes, 79 annotations)
                                                                                                                is-ainactivation of MAPK activity +
                                                                                                                is-anegative regulation of JUN kinase activity
                                                                                                        is-anegative regulation of myosin light chain kinase activity
                                                                                                        is-anegative regulation of Rho-dependent protein serine/threonine kinase activity


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of metabolic process
                                        is-aregulation of cellular metabolic process
                                                is-aregulation of phosphorus metabolic process
                                                        is-aregulation of phosphate metabolic process
                                                                is-aregulation of phosphorylation
                                                                        is-aregulation of protein phosphorylation
                                                                                is-aregulation of protein kinase activity
                                                                                        is-aregulation of protein serine/threonine kinase activity
                                                                                                is-anegative regulation of protein serine/threonine kinase activity
                                                                                                        is-ainactivation of MAPKKK activity
                                                                                                        is-anegative regulation of cAMP-dependent protein kinase activity
                                                                                                        is-anegative regulation of cyclin-dependent protein serine/threonine kinase activity +
                                                                                                        is-anegative regulation of MAP kinase activity [GO:0043407] (60 genes, 79 annotations)
                                                                                                                is-ainactivation of MAPK activity +
                                                                                                                is-anegative regulation of JUN kinase activity
                                                                                                        is-anegative regulation of myosin light chain kinase activity
                                                                                                        is-anegative regulation of Rho-dependent protein serine/threonine kinase activity


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of metabolic process
                                        is-aregulation of cellular metabolic process
                                                is-a