Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Foxo3

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes FOXO3,FOXO3B
- Mouse genes Foxo3
- Rat genes Foxo3
- Zfish genes foxo3a,foxo3b
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Foxo3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008013	beta-catenin binding	FOXO3	IPI	UniProtKB:P35222	Human	PMID:15905404
Molecular Function	GO:0031490	chromatin DNA binding	Foxo3	IDA		Mouse	MGI:MGI:5572869\|PMID:17521387
Molecular Function	GO:0003677	DNA binding	FOXO3	IDA		Human	PMID:21329882
Molecular Function	GO:0003677	DNA binding	Foxo3	IDA		Mouse	PMID:15383658
Molecular Function	GO:0003677	DNA binding	Foxo3	IDA		Mouse	PMID:14966295
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Foxo3	IDA		Mouse	MGI:MGI:4881905\|PMID:19933931
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Foxo3	IDA		Mouse	MGI:MGI:6414737\|PMID:32103177
Molecular Function	GO:0003700	DNA-binding transcription factor activity	FOXO3	IDA		Human	PMID:14734530
Molecular Function	GO:0003700	DNA-binding transcription factor activity	FOXO3	IDA		Human	PMID:30513302
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Foxo3	IDA		Mouse	MGI:MGI:3771681\|PMID:18054315
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Foxo3	IDA		Mouse	MGI:MGI:3771642\|PMID:18054316
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Foxo3	IDA		Mouse	PMID:14966295
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Foxo3	IDA		Mouse	PMID:15322035
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	FOXO3	IDA		Human	PMID:20371612
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	Foxo3	IGI	MGI:MGI:1890077	Mouse	PMID:19896444
Molecular Function	GO:0034246	mitochondrial transcription factor activity	FOXO3	IMP		Human	PMID:29445193
Molecular Function	GO:0034246	mitochondrial transcription factor activity	Foxo3	IMP		Mouse	MGI:MGI:6120139\|PMID:23283301
Molecular Function	GO:0005515	protein binding	FOXO3	IPI	UniProtKB:P31749	Human	PMID:10102273
Molecular Function	GO:0005515	protein binding	FOXO3	IPI	UniProtKB:P63104	Human	PMID:10102273
Molecular Function	GO:0005515	protein binding	FOXO3	IPI	UniProtKB:P63104	Human	PMID:11864996
Molecular Function	GO:0005515	protein binding	FOXO3	IPI	UniProtKB:Q96EB6	Human	PMID:14976264
Molecular Function	GO:0005515	protein binding	FOXO3	IPI	UniProtKB:P84022	Human	PMID:15084259
Molecular Function	GO:0005515	protein binding	FOXO3	IPI	UniProtKB:Q13485	Human	PMID:15084259
Molecular Function	GO:0005515	protein binding	FOXO3	IPI	UniProtKB:Q60987	Human	PMID:15084259
Molecular Function	GO:0005515	protein binding	FOXO3	IPI	UniProtKB:O14920	Human	PMID:15084260
Molecular Function	GO:0005515	protein binding	FOXO3	IPI	UniProtKB:Q92793	Human	PMID:15126506
Molecular Function	GO:0005515	protein binding	FOXO3	IPI	UniProtKB:Q96EB6	Human	PMID:15126506
Molecular Function	GO:0005515	protein binding	FOXO3	IPI	UniProtKB:Q08050	Human	PMID:16809346
Molecular Function	GO:0005515	protein binding	FOXO3	IPI	UniProtKB:P03372	Human	PMID:18312651
Molecular Function	GO:0005515	protein binding	FOXO3	IPI	UniProtKB:Q92731	Human	PMID:18312651
Molecular Function	GO:0005515	protein binding	FOXO3	IPI	UniProtKB:P01106	Human	PMID:18393360
Molecular Function	GO:0005515	protein binding	FOXO3	IPI	UniProtKB:P11309-1	Human	PMID:18593906
Molecular Function	GO:0005515	protein binding	FOXO3	IPI	UniProtKB:O60356	Human	PMID:20181828
Molecular Function	GO:0005515	protein binding	FOXO3	IPI	UniProtKB:P84022	Human	PMID:21532621
Molecular Function	GO:0005515	protein binding	FOXO3	IPI	UniProtKB:Q13485	Human	PMID:21532621
Molecular Function	GO:0005515	protein binding	FOXO3	IPI	UniProtKB:P31749	Human	PMID:21621563
Molecular Function	GO:0005515	protein binding	FOXO3	IPI	UniProtKB:P63101	Human	PMID:21621563
Molecular Function	GO:0005515	protein binding	FOXO3	IPI	UniProtKB:P51610	Human	PMID:21909281
Molecular Function	GO:0005515	protein binding	FOXO3	IPI	UniProtKB:P35638	Human	PMID:22761832
Molecular Function	GO:0005515	protein binding	FOXO3	IPI	UniProtKB:O00411,UniProtKB:Q9NTG7	Human	PMID:23283301
Molecular Function	GO:0005515	protein binding	FOXO3	IPI	UniProtKB:P31749	Human	PMID:25241761
Molecular Function	GO:0005515	protein binding	FOXO3	IPI	UniProtKB:O75529	Human	PMID:25609649
Molecular Function	GO:0005515	protein binding	FOXO3	IPI	UniProtKB:P06400	Human	PMID:25609649
Molecular Function	GO:0005515	protein binding	FOXO3	IPI	UniProtKB:P28749	Human	PMID:25609649
Molecular Function	GO:0005515	protein binding	FOXO3	IPI	UniProtKB:P30260	Human	PMID:25609649
Molecular Function	GO:0005515	protein binding	FOXO3	IPI	UniProtKB:P85037	Human	PMID:25609649
Molecular Function	GO:0005515	protein binding	FOXO3	IPI	UniProtKB:Q92793	Human	PMID:25609649
Molecular Function	GO:0005515	protein binding	FOXO3	IPI	UniProtKB:Q92974	Human	PMID:25609649
Molecular Function	GO:0005515	protein binding	FOXO3	IPI	UniProtKB:Q96T60	Human	PMID:25609649
Molecular Function	GO:0005515	protein binding	FOXO3	IPI	UniProtKB:P63104	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	FOXO3	IPI	UniProtKB:O00411,UniProtKB:Q00059,UniProtKB:Q9NTG7	Human	PMID:29445193
Molecular Function	GO:0005515	protein binding	Foxo3	IPI	UniProtKB:Q8VDQ8\|UniProtKB:Q923E4	Mouse	MGI:MGI:5572869\|PMID:17521387
Molecular Function	GO:0005515	protein binding	Foxo3	IPI	UniProtKB:Q8BKF1,UniProtKB:Q8R104	Mouse	MGI:MGI:6120139\|PMID:23283301
Molecular Function	GO:0005515	protein binding	Foxo3	IPI	UniProtKB:Q8WTS6	Mouse	MGI:MGI:5508710\|PMID:22402663
Molecular Function	GO:0005515	protein binding	Foxo3	IPI	UniProtKB:P0DJI6	Mouse	MGI:MGI:5426078\|PMID:22510882
Molecular Function	GO:0005515	protein binding	foxo3b	IPI	ZFIN:ZDB-GENE-980526-268	Zfish	PMID:24445282
Molecular Function	GO:0005515	protein binding	foxo3b	IPI	ZFIN:ZDB-GENE-980526-164	Zfish	PMID:24445282
Molecular Function	GO:0019901	protein kinase binding	FOXO3	IPI	UniProtKB:Q13043	Human	PMID:16751106
Molecular Function	GO:0019901	protein kinase binding	FOXO3	IPI	UniProtKB:P11309	Human	PMID:18593906
Molecular Function	GO:0019901	protein kinase binding	FOXO3	IPI	UniProtKB:Q8IW41	Human	PMID:21329882
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Foxo3	IDA		Mouse	MGI:MGI:5572869\|PMID:17521387
Molecular Function	GO:0043565	sequence-specific DNA binding	FOXO3	IDA		Human	PMID:10102273
Molecular Function	GO:0043565	sequence-specific DNA binding	Foxo3	IDA		Mouse	PMID:11353388
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	FOXO3	IDA		Human	PMID:28473536
Molecular Function	GO:0000976	transcription cis-regulatory region binding	Foxo3	IDA		Mouse	MGI:MGI:4881905\|PMID:19933931
Molecular Function	GO:0001221	transcription coregulator binding	Foxo3	IPI	RGD:620036	Rat	PMID:22292478\|RGD:7349318
Cellular Component	GO:0005737	cytoplasm	FOXO3	IDA		Human	PMID:10102273
Cellular Component	GO:0005737	cytoplasm	FOXO3	IDA		Human	PMID:15084260
Cellular Component	GO:0005737	cytoplasm	FOXO3	IDA		Human	PMID:16751106
Cellular Component	GO:0005737	cytoplasm	FOXO3	IDA		Human	PMID:20371612
Cellular Component	GO:0005737	cytoplasm	FOXO3	IDA		Human	PMID:21329882
Cellular Component	GO:0005737	cytoplasm	FOXO3	IDA		Human	PMID:23283301
Cellular Component	GO:0005737	cytoplasm	Foxo3	IDA		Mouse	MGI:MGI:6120139\|PMID:23283301
Cellular Component	GO:0005737	cytoplasm	Foxo3	IDA		Mouse	MGI:MGI:6414737\|PMID:32103177
Cellular Component	GO:0005737	cytoplasm	Foxo3	IDA		Mouse	PMID:14966295
Cellular Component	GO:0005737	cytoplasm	Foxo3	IDA		Mouse	PMID:15383658
Cellular Component	GO:0005737	cytoplasm	Foxo3	IDA		Mouse	PMID:12857750
Cellular Component	GO:0005737	cytoplasm	Foxo3	IDA		Rat	PMID:22362515\|RGD:12790646
Cellular Component	GO:0005829	cytosol	FOXO3	IDA		Human	PMID:23640897
Cellular Component	GO:0005829	cytosol	Foxo3	IDA		Mouse	MGI:MGI:3771681\|PMID:18054315
Cellular Component	GO:0005829	cytosol	Foxo3	IDA		Rat	PMID:17916612\|RGD:2302520
Cellular Component	GO:0016020	membrane	Foxo3	IDA		Mouse	PMID:15383658
Cellular Component	GO:0005759	mitochondrial matrix	FOXO3	IDA		Human	PMID:29445193
Cellular Component	GO:0005759	mitochondrial matrix	Foxo3	IDA		Mouse	MGI:MGI:6119906\|PMID:29445193
Cellular Component	GO:0005741	mitochondrial outer membrane	FOXO3	IDA		Human	PMID:29445193
Cellular Component	GO:0005741	mitochondrial outer membrane	Foxo3	IDA		Mouse	MGI:MGI:6119906\|PMID:29445193
Cellular Component	GO:0005739	mitochondrion	FOXO3	IDA		Human	PMID:23283301
Cellular Component	GO:0005739	mitochondrion	Foxo3	IDA		Mouse	MGI:MGI:6120139\|PMID:23283301
Cellular Component	GO:0005739	mitochondrion	Foxo3	IDA		Rat	PMID:23278239\|RGD:10402198
Cellular Component	GO:0005654	nucleoplasm	FOXO3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	FOXO3	IDA		Human	PMID:10102273
Cellular Component	GO:0005634	nucleus	FOXO3	IDA		Human	PMID:15084260
Cellular Component	GO:0005634	nucleus	FOXO3	IDA		Human	PMID:16751106
Cellular Component	GO:0005634	nucleus	FOXO3	IDA		Human	PMID:18393360
Cellular Component	GO:0005634	nucleus	FOXO3	IDA		Human	PMID:21329882
Cellular Component	GO:0005634	nucleus	FOXO3	IDA		Human	PMID:22761832
Cellular Component	GO:0005634	nucleus	FOXO3	IDA		Human	PMID:23283301
Cellular Component	GO:0005634	nucleus	FOXO3	IDA		Human	PMID:23640897
Cellular Component	GO:0005634	nucleus	FOXO3	IDA		Human	PMID:25327288
Cellular Component	GO:0005634	nucleus	FOXO3	IMP		Human	PMID:29445193
Cellular Component	GO:0005634	nucleus	Foxo3	IDA		Mouse	MGI:MGI:3771681\|PMID:18054315
Cellular Component	GO:0005634	nucleus	Foxo3	IDA		Mouse	MGI:MGI:6120139\|PMID:23283301
Cellular Component	GO:0005634	nucleus	Foxo3	IDA		Mouse	MGI:MGI:6414737\|PMID:32103177
Cellular Component	GO:0005634	nucleus	Foxo3	IDA		Mouse	PMID:12857750
Cellular Component	GO:0005634	nucleus	Foxo3	IDA		Mouse	PMID:14966295
Cellular Component	GO:0005634	nucleus	Foxo3	IDA		Rat	PMID:17916612\|RGD:2302520
Cellular Component	GO:0005634	nucleus	Foxo3	IDA		Rat	PMID:22362515\|RGD:12790646
Cellular Component	GO:0032991	protein-containing complex	FOXO3	IDA		Human	PMID:23283301
Cellular Component	GO:0032991	protein-containing complex	FOXO3	IDA		Human	PMID:29445193
Cellular Component	GO:0032991	protein-containing complex	Foxo3	IDA		Mouse	MGI:MGI:6120139\|PMID:23283301
Cellular Component	GO:0090571	RNA polymerase II transcription repressor complex	FOXO3	IPI		Human	PMID:18393360
Biological Process	GO:0007568	aging	Foxo3	IDA		Rat	PMID:24669284\|RGD:10402194
Biological Process	GO:0001547	antral ovarian follicle growth	Foxo3	IMP	MGI:MGI:3038979	Mouse	PMID:14978268
Biological Process	GO:0006915	apoptotic process	Foxo3	IEP		Rat	PMID:19258007\|RGD:10402200
Biological Process	GO:0048854	brain morphogenesis	Foxo3	IGI	MGI:MGI:2448480,MGI:MGI:95480	Mouse	PMID:24483844
Biological Process	GO:0060070	canonical Wnt signaling pathway	Foxo3	IGI	MGI:MGI:1890077	Mouse	PMID:19896444
Biological Process	GO:0060070	canonical Wnt signaling pathway	Foxo3	IGI	MGI:MGI:98956	Mouse	PMID:19896444
Biological Process	GO:1904646	cellular response to amyloid-beta	Foxo3	IEP		Rat	PMID:23661003\|RGD:10402187
Biological Process	GO:0071386	cellular response to corticosterone stimulus	Foxo3	IEP		Rat	PMID:23494228\|RGD:10402192
Biological Process	GO:0042149	cellular response to glucose starvation	FOXO3	IDA		Human	PMID:29445193
Biological Process	GO:0071333	cellular response to glucose stimulus	Foxo3	IEP		Rat	PMID:24183892\|RGD:9495918
Biological Process	GO:0071456	cellular response to hypoxia	Foxo3	IEP		Rat	PMID:24278276\|RGD:10402204
Biological Process	GO:1990090	cellular response to nerve growth factor stimulus	Foxo3	IEP		Rat	PMID:24183892\|RGD:9495918
Biological Process	GO:0034599	cellular response to oxidative stress	Foxo3	IDA		Mouse	MGI:MGI:5572869\|PMID:17521387
Biological Process	GO:0034599	cellular response to oxidative stress	Foxo3	IGI	MGI:MGI:2448480,MGI:MGI:95480	Mouse	PMID:24483844
Biological Process	GO:0043009	chordate embryonic development	foxo3b	IMP	ZFIN:ZDB-MRPHLNO-110929-9	Zfish	PMID:21915332
Biological Process	GO:0030330	DNA damage response, signal transduction by p53 class mediator	Foxo3	IDA		Mouse	PMID:15383658
Biological Process	GO:0097192	extrinsic apoptotic signaling pathway in absence of ligand	Foxo3	IGI	MGI:MGI:1096330	Mouse	PMID:12431371
Biological Process	GO:0042593	glucose homeostasis	Foxo3	IMP	MGI:MGI:2668328	Mouse	PMID:12855809
Biological Process	GO:0001544	initiation of primordial ovarian follicle growth	Foxo3	IMP	MGI:MGI:2668328	Mouse	PMID:12855809
Biological Process	GO:0006390	mitochondrial transcription	FOXO3	IMP		Human	PMID:29445193
Biological Process	GO:0006390	mitochondrial transcription	Foxo3	IMP		Mouse	MGI:MGI:6120139\|PMID:23283301
Biological Process	GO:0090090	negative regulation of canonical Wnt signaling pathway	Foxo3	IGI	MGI:MGI:98956	Mouse	PMID:19896444
Biological Process	GO:0090090	negative regulation of canonical Wnt signaling pathway	Foxo3	IGI	MGI:MGI:1890077	Mouse	PMID:19896444
Biological Process	GO:0090090	negative regulation of canonical Wnt signaling pathway	foxo3b	IMP	ZFIN:ZDB-MRPHLNO-110929-9	Zfish	PMID:21915332
Biological Process	GO:0090090	negative regulation of canonical Wnt signaling pathway	foxo3b	IDA		Zfish	PMID:21915332
Biological Process	GO:0030336	negative regulation of cell migration	FOXO3	IMP		Human	PMID:19188590
Biological Process	GO:0050687	negative regulation of defense response to virus	foxo3b	IMP	ZFIN:ZDB-GENO-170405-4	Zfish	PMID:27815423
Biological Process	GO:0050687	negative regulation of defense response to virus	foxo3b	IMP	ZFIN:ZDB-MRPHLNO-110929-10	Zfish	PMID:27815423
Biological Process	GO:0045665	negative regulation of neuron differentiation	Foxo3	IMP		Rat	PMID:23086522\|RGD:10402193
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	FOXO3	IDA		Human	PMID:18393360
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	FOXO3	IMP		Human	PMID:18787191
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	FOXO3	IDA		Human	PMID:20371612
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	FOXO3	IDA		Human	PMID:21621563
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Foxo3	IDA		Mouse	MGI:MGI:5908335\|PMID:21621563
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	foxo3b	IDA		Zfish	PMID:24445282
Biological Process	GO:0030178	negative regulation of Wnt signaling pathway	foxo3b	IGI	ZFIN:ZDB-MRPHLNO-060414-1,ZFIN:ZDB-MRPHLNO-110929-9	Zfish	PMID:21915332
Biological Process	GO:0030178	negative regulation of Wnt signaling pathway	foxo3b	IPI	ZFIN:ZDB-GENE-040426-2575	Zfish	PMID:21915332
Biological Process	GO:0030178	negative regulation of Wnt signaling pathway	foxo3b	IPI	ZFIN:ZDB-GENE-980526-362	Zfish	PMID:21915332
Biological Process	GO:0097150	neuronal stem cell population maintenance	Foxo3	IGI	MGI:MGI:2448480,MGI:MGI:95480	Mouse	PMID:24483844
Biological Process	GO:0097150	neuronal stem cell population maintenance	Foxo3	IGI	MGI:MGI:1890077	Mouse	PMID:19896444
Biological Process	GO:0001556	oocyte maturation	Foxo3	IMP	MGI:MGI:2668328	Mouse	PMID:12855809
Biological Process	GO:0001542	ovulation from ovarian follicle	Foxo3	IMP	MGI:MGI:2668328	Mouse	PMID:12855809
Biological Process	GO:0043065	positive regulation of apoptotic process	FOXO3	IDA		Human	PMID:20371612
Biological Process	GO:0010508	positive regulation of autophagy	Foxo3	IDA		Mouse	MGI:MGI:3771642\|PMID:18054316
Biological Process	GO:0010508	positive regulation of autophagy	Foxo3	IDA		Mouse	MGI:MGI:3771681\|PMID:18054315
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	FOXO3	IDA		Human	PMID:10102273
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	FOXO3	IDA		Human	PMID:15084260
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Foxo3	IDA		Mouse	MGI:MGI:3771681\|PMID:18054315
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Foxo3	IDA		Mouse	MGI:MGI:3771642\|PMID:18054316
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Foxo3	IDA		Mouse	PMID:12048180
Biological Process	GO:2000353	positive regulation of endothelial cell apoptotic process	Foxo3	IMP		Rat	PMID:24278276\|RGD:10402204
Biological Process	GO:0045648	positive regulation of erythrocyte differentiation	FOXO3	IDA		Human	PMID:14734530
Biological Process	GO:1901300	positive regulation of hydrogen peroxide-mediated programmed cell death	Foxo3	IMP		Rat	PMID:23585551\|RGD:7327146
Biological Process	GO:1902895	positive regulation of miRNA transcription	Foxo3	IMP		Mouse	MGI:MGI:4881905\|PMID:19933931
Biological Process	GO:0014737	positive regulation of muscle atrophy	Foxo3	IDA		Mouse	MGI:MGI:3771642\|PMID:18054316
Biological Process	GO:0014737	positive regulation of muscle atrophy	Foxo3	IDA		Mouse	MGI:MGI:3771681\|PMID:18054315
Biological Process	GO:0043525	positive regulation of neuron apoptotic process	FOXO3	IMP		Human	PMID:10102273
Biological Process	GO:1903428	positive regulation of reactive oxygen species biosynthetic process	Foxo3	IMP		Rat	PMID:24278276\|RGD:10402204
Biological Process	GO:0045591	positive regulation of regulatory T cell differentiation	FOXO3	IDA		Human	PMID:30513302
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	FOXO3	IDA		Human	PMID:14734530
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	FOXO3	IDA		Human	PMID:10102273
Biological Process	GO:0060215	primitive hemopoiesis	foxo3b	IGI	ZFIN:ZDB-GENE-040625-109	Zfish	PMID:24445282
Biological Process	GO:0006355	regulation of DNA-templated transcription	Foxo3	IDA		Mouse	PMID:12930811
Biological Process	GO:0051960	regulation of nervous system development	foxo3a	IMP	ZFIN:ZDB-MRPHLNO-101116-3	Zfish	PMID:20674670
Biological Process	GO:2000177	regulation of neural precursor cell proliferation	Foxo3	IGI	MGI:MGI:1890077	Mouse	PMID:19896444
Biological Process	GO:0043523	regulation of neuron apoptotic process	foxo3a	IMP	ZFIN:ZDB-MRPHLNO-101116-3	Zfish	PMID:20674670
Biological Process	GO:2000377	regulation of reactive oxygen species metabolic process	Foxo3	IGI	MGI:MGI:1890077	Mouse	PMID:19896444
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	Foxo3	IDA		Mouse	MGI:MGI:5572869\|PMID:17521387
Biological Process	GO:0006417	regulation of translation	FOXO3	IDA		Human	PMID:21329882
Biological Process	GO:0071548	response to dexamethasone	Foxo3	IEP		Rat	PMID:12683947\|RGD:10402199
Biological Process	GO:0070542	response to fatty acid	Foxo3	IDA		Mouse	MGI:MGI:6414737\|PMID:32103177
Biological Process	GO:0001666	response to hypoxia	foxo3b	IMP	ZFIN:ZDB-GENO-170405-4	Zfish	PMID:27777301
Biological Process	GO:0031667	response to nutrient levels	Foxo3	IEP		Rat	PMID:12683947\|RGD:10402199
Biological Process	GO:0042594	response to starvation	Foxo3	IDA		Mouse	MGI:MGI:3771642\|PMID:18054316
Biological Process	GO:0042594	response to starvation	Foxo3	IDA		Mouse	MGI:MGI:3771681\|PMID:18054315
Biological Process	GO:1990785	response to water-immersion restraint stress	Foxo3	IEP		Rat	PMID:23079979\|RGD:10402359
Biological Process	GO:0009410	response to xenobiotic stimulus	Foxo3	IEP		Rat	PMID:23494228\|RGD:10402192
Biological Process	GO:0033209	tumor necrosis factor-mediated signaling pathway	FOXO3	IMP		Human	PMID:15084260

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.