Excel File Text File *Disease is associated/modeled with this Gene or a homolog. More...
      Disease Term Human Homologs Mouse Homologs Mouse Models Homology Source
     hereditary neutrophilia CSF3R* Csf3r* 1 model Alliance of Genome Resources
leukocyte adhesion deficiency 1 ITGB2* Itgb2*, Itgb2l 3 models Alliance of Genome Resources
leukocyte adhesion deficiency 3 FERMT3* Fermt3* 1 model Alliance of Genome Resources
mastocytosis KIT* Kit* 5 models Alliance of Genome Resources
     leukocyte adhesion deficiency 3 RASGRP2 Rasgrp2* 1 model Alliance of Genome Resources
leukopenia NUDT15 Nudt15* 2 models Alliance of Genome Resources
multiple myeloma MAF Maf* 2 models Alliance of Genome Resources
neutropenia NUDT15 Nudt15* 2 models Alliance of Genome Resources
severe congenital neutropenia GFI1 Gfi1* 1 model Alliance of Genome Resources
     agranulocytosis IL1B* Il1b   Alliance of Genome Resources
agranulocytosis HLA-DQB1*, HLA-DQB2 H2-Ab1   Alliance of Genome Resources
agranulocytosis NQO2* Nqo2   Alliance of Genome Resources
cyclic hematopoiesis ELANE* Elane   Alliance of Genome Resources
hypereosinophilic syndrome PDGFRA* Pdgfra   Alliance of Genome Resources
hypereosinophilic syndrome F5* F5   Alliance of Genome Resources
leukocyte adhesion deficiency ITGB2* Itgb2, Itgb2l   Alliance of Genome Resources
leukocyte adhesion deficiency 1 FERMT3* Fermt3   Alliance of Genome Resources
leukopenia GSTM1*, GSTM5 Gstm1, Gstm2, Gstm3, Gstm6   Alliance of Genome Resources
leukopenia TPMT* Tpmt   Alliance of Genome Resources
leukopenia GSTT1* Gstt1   Alliance of Genome Resources
leukopenia CXCR4* Cxcr4   Alliance of Genome Resources
leukostasis SERPINF1* Serpinf1   Alliance of Genome Resources
lymphopenia FCGR3A*, FCGR3B Fcgr4   Alliance of Genome Resources
lymphopenia FCGR2A*, FCGR2B, FCGR2C Fcgr2b, Fcgr3   Alliance of Genome Resources
lymphopenia IL2RA* Il2ra   Alliance of Genome Resources
mastocytosis IL13* Il13   Alliance of Genome Resources
multiple myeloma TYMS* Tyms   Alliance of Genome Resources
multiple myeloma POLR1G* Polr1g   Alliance of Genome Resources
multiple myeloma PON1* Pon1   Alliance of Genome Resources
multiple myeloma RBP1* Rbp1   Alliance of Genome Resources
multiple myeloma ROBO1* Robo1   Alliance of Genome Resources
multiple myeloma SOD2* Sod2   Alliance of Genome Resources
multiple myeloma SPARC* Sparc   Alliance of Genome Resources
multiple myeloma SPP1* Spp1   Alliance of Genome Resources
multiple myeloma TFRC* Tfrc   Alliance of Genome Resources
multiple myeloma TGFB1* Tgfb1   Alliance of Genome Resources
multiple myeloma TNF* Tnf   Alliance of Genome Resources
multiple myeloma TNFRSF10A*, TNFRSF10B, TNFRSF10C, TNFRSF10D Tnfrsf10b   Alliance of Genome Resources
multiple myeloma TNFRSF17* Tnfrsf17   Alliance of Genome Resources
multiple myeloma TP53* Trp53   Alliance of Genome Resources
multiple myeloma VEGFA* Vegfa   Alliance of Genome Resources
multiple myeloma XPO5* Xpo5   Alliance of Genome Resources
multiple myeloma XRCC3* Xrcc3   Alliance of Genome Resources
multiple myeloma XRCC4* Xrcc4   Alliance of Genome Resources
multiple myeloma XRCC5* Xrcc5   Alliance of Genome Resources
multiple myeloma ABCG2* Abcg2, Abcg3   Alliance of Genome Resources
multiple myeloma ACE* Ace   Alliance of Genome Resources
multiple myeloma APOE* Apoe   Alliance of Genome Resources
multiple myeloma BCL2L10* Bcl2l10   Alliance of Genome Resources
multiple myeloma CBX7* Cbx7   Alliance of Genome Resources
multiple myeloma CCND1* Ccnd1   Alliance of Genome Resources
multiple myeloma CD40* Cd40   Alliance of Genome Resources
multiple myeloma CD40LG* Cd40lg   Alliance of Genome Resources
multiple myeloma CDKN2A* Cdkn2a   Alliance of Genome Resources
multiple myeloma CFHR1*, CFHR2 Cfhr1   Alliance of Genome Resources
multiple myeloma CTLA4* Ctla4   Alliance of Genome Resources
multiple myeloma CYP1A1* Cyp1a1   Alliance of Genome Resources
multiple myeloma CYP2C19*, CYP2C8, CYP2C9, CYP2C18 Cyp2c29, Cyp2c37, Cyp2c38, Cyp2c39, Cyp2c50, Cyp2c55, Cyp2c65, Cyp2c66   Alliance of Genome Resources
multiple myeloma EPHX1* Ephx1   Alliance of Genome Resources
multiple myeloma ERCC1* Ercc1   Alliance of Genome Resources
multiple myeloma ERCC2* Ercc2   Alliance of Genome Resources
multiple myeloma FCGR2A*, FCGR2B, FCGR2C Fcgr2b, Fcgr3   Alliance of Genome Resources
multiple myeloma FGG* Fgg   Alliance of Genome Resources
multiple myeloma GPX1* Gpx1   Alliance of Genome Resources
multiple myeloma GPX3* Gpx3   Alliance of Genome Resources
multiple myeloma GSTM1*, GSTM5 Gstm1, Gstm2, Gstm3, Gstm6   Alliance of Genome Resources
multiple myeloma GSTP1* Gstp1, Gstp2, Gstp3, Gstp-ps   Alliance of Genome Resources
multiple myeloma GSTT1* Gstt1   Alliance of Genome Resources
multiple myeloma HFE* Hfe   Alliance of Genome Resources
multiple myeloma HK1* Hk1   Alliance of Genome Resources
multiple myeloma ICAM1* Icam1   Alliance of Genome Resources
multiple myeloma IL1A* Il1a   Alliance of Genome Resources
multiple myeloma IL1B* Il1b   Alliance of Genome Resources
multiple myeloma IL1RN* Il1rn   Alliance of Genome Resources
multiple myeloma IL4R* Il4ra   Alliance of Genome Resources
multiple myeloma IL10* Il10   Alliance of Genome Resources
multiple myeloma IRF4* Irf4   Alliance of Genome Resources
multiple myeloma IRF8* Irf8   Alliance of Genome Resources
multiple myeloma KRAS* Kras   Alliance of Genome Resources
multiple myeloma LIG4* Lig4   Alliance of Genome Resources
multiple myeloma MEFV* Mefv   Alliance of Genome Resources
multiple myeloma MET* Met   Alliance of Genome Resources
multiple myeloma MIR320A* Mir320   Alliance of Genome Resources
multiple myeloma MTHFR* Mthfr   Alliance of Genome Resources
multiple myeloma MTR* Mtr   Alliance of Genome Resources
multiple myeloma MTRR* Mtrr   Alliance of Genome Resources
multiple myeloma NFKBIA* Nfkbia   Alliance of Genome Resources
multiple myeloma NQO1* Nqo1   Alliance of Genome Resources
multiple myeloma NRAS* Nras   Alliance of Genome Resources
multiple myeloma PF4*, PF4V1 Pf4   Alliance of Genome Resources
neutropenia FCGR2A*, FCGR2B, FCGR2C Fcgr2b, Fcgr3   Alliance of Genome Resources
neutropenia CSF3* Csf3   Alliance of Genome Resources
neutropenia AP3B1* Ap3b1   Alliance of Genome Resources
neutropenia TNF* Tnf   Alliance of Genome Resources
neutropenia CSF2* Csf2   Alliance of Genome Resources
neutropenia STAT2* Stat2   Alliance of Genome Resources
neutropenia C5* Hc   Alliance of Genome Resources
neutropenia GSTT1* Gstt1   Alliance of Genome Resources
severe congenital neutropenia ELANE* Elane   Alliance of Genome Resources
severe congenital neutropenia CSF3R* Csf3r   Alliance of Genome Resources
severe congenital neutropenia CLPB* Clpb   Alliance of Genome Resources
severe congenital neutropenia SRP68* Srp68   Alliance of Genome Resources
severe congenital neutropenia 1 ELANE* Elane   Alliance of Genome Resources
severe congenital neutropenia 2 GFI1* Gfi1   Alliance of Genome Resources
severe congenital neutropenia 3 HAX1* Hax1   Alliance of Genome Resources
severe congenital neutropenia 4 G6PC3* G6pc3   Alliance of Genome Resources
severe congenital neutropenia 5 VPS45* Vps45   Alliance of Genome Resources
severe congenital neutropenia 6 JAGN1* Jagn1   Alliance of Genome Resources
severe congenital neutropenia 7 CSF3R* Csf3r   Alliance of Genome Resources
severe congenital neutropenia 8 SRP54* Srp54a, Srp54b, Srp54c   Alliance of Genome Resources
SM-AHNMD ASXL1* Asxl1   Alliance of Genome Resources
X-linked severe congenital neutropenia WAS* Was   Alliance of Genome Resources

 
Transgenes and other genome features developed in mice to model this disease.
     Disease Term Transgenes and Other Genome Features Mouse Models
  mastocytosis Tg(Kit*D814V)2Roer 1 model
  mastocytosis Tg(Kit*D814V)3Roer 2 models
  mastocytosis Tg(Kit*D814V)1Roer 2 models
  multiple myeloma Tg(Cd4-NPM/ALK)N1Ingh 1 model
  multiple myeloma Tg(Igh-Maf)68Staka 1 model
  multiple myeloma Tg(Igh-Maf)524Staka 1 model
  multiple myeloma Tg(Igkv3-5*-MYC)24Plbe 1 model