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Srp54c Gene Detail
Summary
  • Symbol
    Srp54c
  • Name
    signal recognition particle 54C
  • Synonyms
    E330029E12Rik
Location &
Maps
more
  • Sequence Map
    Chr12:55276953-55310621 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 12, 23.89 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    272 from dbSNP Build 142
  • Strain Annotations
    11
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3714359
 protein coding gene Chr12:55276896-55326120 (+)
129S1/SvImJ no annotation
A/J ENSMUSG00195016812
 protein coding gene Chr12:49750971-49784648 (+)
AKR/J ENSMUSG00220025723
 protein coding gene Chr12:47769326-47803005 (+)
BALB/cJ ENSMUSG00180005976
 protein coding gene Chr12:48771925-48805607 (+)
C3H/HeJ ENSMUSG00175016421
 protein coding gene Chr12:51813035-51846714 (+)
C57BL/6NJ no annotation
CAROLI/EiJ MGP_CAROLIEiJ_G0017754
 protein coding gene Chr12:50404743-50439276 (+)
CAST/EiJ no annotation
CBA/J ENSMUSG00210009487
 protein coding gene Chr12:48287329-48321014 (+)
DBA/2J ENSMUSG00185000941
 protein coding gene Chr12:50232754-50266434 (+)
FVB/NJ ENSMUSG00205012153
 protein coding gene Chr12:48073904-48107616 (+)
JF1/MsJ no annotation
LP/J no annotation
NOD/ShiLtJ ENSMUSG00190015784
 protein coding gene Chr12:47281150-47314830 (+)
NZO/HlLtJ no annotation
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ ENSIUOG00005003459
 protein coding gene Chr12:48120295-48153986 (+)



Homology
more
  • Human Ortholog
    SRP54, signal recognition particle 54
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SRP54, signal recognition particle 54
  • Synonyms
    SCN8
  • Links
    NCBI Gene ID: 6729
    UniProt: P61011

  • Chr Location
    14q13.2; chr14:34981957-35029686 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human SRP54 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    38
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    10
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000079108 Ensembl Gene Model | MGI Sequence Detail 33669 C57BL/6J ±  kb
transcript ENSMUST00000218879 Ensembl | MGI Sequence Detail 3642 Not Applicable  
polypeptide ENSMUSP00000151681 Ensembl | MGI Sequence Detail 504 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • EC
    3.6.5.-
  • InterPro Domains
    IPR003593 AAA+ ATPase domain
    IPR028260 FAM177 family
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
    IPR013822 Signal recognition particle SRP54, helical bundle
    IPR042101 Signal recognition particle SRP54, N-terminal domain superfamily
    IPR022941 Signal recognition particle, SRP54 subunit
    IPR006325 Signal recognition particle, SRP54 subunit, eukaryotic
    IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain
    IPR004125 Signal recognition particle, SRP54 subunit, M-domain
    IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily
Molecular
Reagents
less
  • All nucleic 11
    cDNA 11

    Microarray probesets 3
Other
Accession IDs
less
MGI:2442031
References
more
  • Summaries
    All 27
    Gene Ontology 6
    Phenotypes 3
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory