Gnas/Nespastm1.1Jop/Gnas+
involves: 129S1/Sv * M. spretus
|
abnormal DNA methylation |
J:171195
|
Gnas/Nespastm1.1Jop/Gnas+
involves: 129S/SvEv * 129S1/Sv
|
abnormal DNA methylation |
J:171195
|
Gnas/Nespastm2.1Jop/Gnas+
involves: 129S/SvEv * 129S1/Sv
|
abnormal DNA methylation |
J:171195
|
GnasOedsml/Gnas+
involves: 101/H * C3H/HeH
|
abnormal coat appearance |
J:65007
|
|
abnormal imprinting |
J:65007
|
|
abnormal inflammatory response |
J:65007
|
|
decreased body weight |
J:65007
|
|
hydrops fetalis |
J:65007
|
|
increased brown adipose tissue amount |
J:65007
|
|
postnatal growth retardation |
J:65007
|
|
postnatal lethality, complete penetrance |
J:65007
|
|
prenatal lethality, incomplete penetrance |
J:65007
|
|
respiratory distress |
J:65007
|
|
small heart |
J:65007
|
GnasOedsml/Gnas+
involves: 101/H * C3H/HeH * M. m. castaneus
|
hydrops fetalis |
J:65007
|
|
postnatal lethality, complete penetrance |
J:65007
|
GnasOedsml/Gnas+
Not Specified
|
decreased birth body size |
J:91717
|
|
decreased circulating calcium level |
J:91717
|
|
decreased heart weight |
J:91717
|
|
edema |
J:91717
|
|
increased circulating parathyroid hormone level |
J:91717
|
|
increased circulating phosphate level |
J:91717
|
GnasOedsml/GnasOedsml
involves: 101/H * C3H/HeH
|
prenatal lethality, complete penetrance |
J:65007
|
GnasOedsml/Gnastm1Jop
involves: 129S/SvEv * C57BL/6
|
abnormal heart size |
J:91717
|
|
normal
homeostasis/metabolism phenotype |
J:91717
|
Gnastm1.1Plag/Gnas+
involves: 129S4/SvJae * C57BL/6 * C57BL/6J * SJL
|
neonatal lethality, incomplete penetrance |
J:184320
|
Gnastm1.1Plag/Gnas+
involves: 129S4/SvJae * C57BL/6 * CD-1 * SJL
|
neonatal lethality, incomplete penetrance |
J:184320
|
Gnastm1.2Plag/Gnas+
involves: 129S4/SvJae * BALB/cJ * C57BL/6 * CD-1 * SJL
|
neonatal lethality, incomplete penetrance |
J:184320
|
Gnastm1Gwa/Gnas+
either: (involves: 129S4/SvJae * 129/Sv) or (involves: 129S4/SvJae * C57BL/6J) or (involves: 129S4/SvJae * CD-1)
|
decreased alcohol consumption |
J:70175
|
Gnastm1Gwa/Gnas+
involves: 129S4/SvJae * C57BL/6J
|
abnormal enzyme/coenzyme activity |
J:70175
|
|
impaired righting response |
J:70175
|
Gnastm1Gwa/Gnas+
involves: 129S/SvEv * 129S4/SvJae
|
abnormal hypodermis morphology |
J:174525
|
|
ectopic bone |
J:174525
|
|
obese |
J:174525
|
|
skin lesions |
J:174525
|
Gnastm1Jop/Gnas+
involves: 129S/SvEv * C57BL/6
|
no abnormal phenotype detected |
J:91717
|
Gnastm1Kel/Gnas+
involves: 129S2/SvPas
|
increased circulating ghrelin level |
J:184320
|
Gnastm1Kel/Gnas+
involves: 129S2/SvPas * C57BL/6J
|
abnormal imprinting |
J:91703
|
|
abnormal suckling behavior |
J:91703
|
|
decreased brown adipose tissue amount |
J:91703
|
|
decreased circulating glucagon level |
J:91703
|
|
decreased circulating glucose level |
J:91703
|
|
decreased circulating insulin level |
J:91703
|
|
decreased interscapular fat pad weight |
J:91703
|
|
decreased locomotor activity |
J:91703
|
|
decreased white adipose tissue amount |
J:91703
|
|
postnatal lethality, complete penetrance |
J:91703
|
|
slow postnatal weight gain |
J:91703
|
|
weakness |
J:91703
|
Gnastm1Kel/Gnas+
involves: 129S2/SvPas * C57BL/6J * CD-1
|
postnatal lethality |
J:91703
|
Gnastm1Lsw/Gnas+
involves: 129S4/SvJae
|
decreased urine osmolality |
J:56867
|
Gnastm1Lsw/Gnas+
involves: 129S4/SvJae * CD-1
|
abnormal blood homeostasis |
J:106729
|
|
abnormal body size |
J:60971
|
|
abnormal brown adipose tissue morphology |
J:60971
|
|
abnormal cerebellar cortex morphology |
J:49340
|
|
abnormal gas homeostasis |
J:60971
|
|
abnormal glucose homeostasis |
J:106729
|
|
abnormal motor capabilities/coordination/movement |
J:49340
|
|
abnormal outer ear morphology |
J:49340
|
|
abnormal posture |
J:49340
|
|
abnormal skin morphology |
J:49340
|
|
absent gastric milk in neonates |
J:49340
|
|
ataxia |
J:49340
|
|
decreased birth body size |
J:49340
|
|
decreased birth weight |
J:49340
|
|
decreased body length |
J:60971
|
|
decreased body mass index |
J:60971
|
|
decreased body weight |
J:60971
|
|
decreased brown adipose tissue amount |
J:60971
|
|
decreased circulating calcium level |
J:49340
|
|
decreased circulating cholesterol level |
J:60971
|
|
decreased circulating glucose level |
J:106729
|
|
decreased circulating insulin level |
J:106729
|
|
decreased circulating triglyceride level |
J:60971
|
|
decreased epididymal fat pad weight |
J:60971
|
|
decreased interscapular fat pad weight |
J:60971
|
|
decreased locomotor activity |
J:60971
|
|
decreased oxygen consumption |
J:60971
|
|
decreased survivor rate |
J:49340
|
|
decreased urine noradrenaline level |
J:60971
|
|
decreased white adipose tissue amount |
J:60971
|
|
delayed kidney development |
J:49340
|
|
genetic imprinting |
J:49340
|
|
normal
homeostasis/metabolism phenotype |
J:60971
|
|
impaired balance |
J:49340
|
|
impaired righting response |
J:49340
|
|
improved glucose tolerance |
J:106729
|
|
increased birth body size |
J:49340
|
|
increased birth weight |
J:49340
|
|
increased body mass index |
J:60971
|
|
increased brown adipose tissue amount |
J:60971
|
|
increased brown fat cell lipid droplet size |
J:60971
|
|
increased circulating parathyroid hormone level |
J:49340
|
|
increased insulin sensitivity |
J:106729
|
|
increased interscapular fat pad weight |
J:60971
|
|
increased lean body mass |
J:49340
|
|
increased locomotor activity |
J:60971
|
|
increased muscle cell glucose uptake |
J:106729
|
|
increased oxygen consumption |
J:60971
|
|
increased urine dopamine level |
J:60971
|
|
increased urine noradrenaline level |
J:60971
|
|
increased white adipose tissue amount |
J:60971
|
|
insensitivity to parathyroid hormone |
J:49340
|
|
neonatal lethality, incomplete penetrance |
J:49340
|
|
no spontaneous movement |
J:49340
|
|
obese |
J:49340
|
|
postnatal growth retardation |
J:49340,
J:60971
|
|
postnatal lethality, incomplete penetrance |
J:49340
|
|
skin edema |
J:49340
|
|
thymus cortex atrophy |
J:49340
|
|
tremors |
J:49340
|
Gnastm1Lsw/Gnastm1Lsw
involves: 129S4/SvJae * CD-1
|
prenatal lethality, complete penetrance |
J:49340
|
Gnastm2.1Lsw/Gnas+
involves: 129S6/SvEvTac * Black Swiss
|
abnormal response/metabolism to endogenous compounds |
J:97229
|
|
decreased circulating parathyroid hormone level |
J:97229
|
|
decreased circulating phosphate level |
J:97229
|
|
maternal imprinting |
J:97229
|
Gnastm2.1Lsw/Gnastm2.1Lsw
involves: 129S6/SvEvTac * CD-1 * FVB/N
|
normal
cellular phenotype |
J:89923
|
Gnastm2Jop/Gnas+
involves: 129S/SvEv
|
abnormal gas homeostasis |
J:182868
|
|
normal
behavior/neurological phenotype |
J:182868
|
|
decreased birth weight |
J:182868
|
|
decreased body length |
J:182868
|
|
decreased bone mineral density |
J:182868
|
|
decreased circulating leptin level |
J:182868
|
|
decreased lean body mass |
J:182868
|
|
decreased percent body fat/body weight |
J:182868
|
|
decreased total body fat amount |
J:182868
|
|
increased basal metabolism |
J:182868
|
|
increased carbon dioxide production |
J:182868
|
|
increased food intake |
J:182868
|
|
increased oxygen consumption |
J:182868
|
|
postnatal lethality, incomplete penetrance |
J:182868
|
|
short femur |
J:182868
|
|
slow postnatal weight gain |
J:182868
|
Gnastm2Kel/Gnas+
either: (involves: 129S1/Sv) or (involves: 129S1/Sv * C57BL/6J)
|
abnormal response to new environment |
J:97634
|
|
hyperactivity |
J:97634
|
|
normal
nervous system phenotype |
J:97634
|
|
paternal imprinting |
J:97634
|
Gnastm3Jop/Gnas+
involves: 129S/SvEv
|
abnormal eating behavior |
J:182868
|
|
normal
behavior/neurological phenotype |
J:182868
|
|
decreased birth weight |
J:182868
|
|
decreased lean body mass |
J:182868
|
|
decreased total body fat amount |
J:182868
|
|
postnatal lethality, incomplete penetrance |
J:182868
|
|
slow postnatal weight gain |
J:182868
|
Gnastm3Kel/Gnas+
involves: 129P2/OlaHsd * C57BL/6J * DS/2
|
abnormal body weight |
J:143477
|
|
abnormal fat pad morphology |
J:143477
|
|
abnormal imprinting |
J:143477
|
|
paternal imprinting |
J:143477
|
|
postnatal lethality, incomplete penetrance |
J:143477
|
Gnastm3Lsw/Gnastm3Lsw
Ren1tm2(cre)Gom/Ren1+
involves: 129S6/SvEvTac * Black Swiss
|
abnormal kidney physiology |
J:118076
|
|
abnormal renin activity |
J:118076
|
|
decreased circulating aldosterone level |
J:118076
|
|
decreased circulating renin level |
J:118076
|
|
decreased mean systemic arterial blood pressure |
J:118076
|
|
decreased renal glomerular filtration rate |
J:118076
|
|
decreased urine osmolality |
J:118076
|
|
increased urine prostaglandin level |
J:118076
|
Gnastm3Lsw/Gnastm3Lsw
Tg(Col2a1-cre)1Rsjo/0
involves: 129S6/SvEvTac * FVB/N
|
abnormal cartilage development |
J:97230
|
|
abnormal long bone epiphyseal plate morphology |
J:97230
|
|
abnormal long bone epiphyseal plate proliferative zone |
J:97230
|
|
abnormal long bone epiphysis morphology |
J:97230
|
|
abnormal pulmonary alveolus morphology |
J:97230
|
|
abnormal tibia morphology |
J:97230
|
|
cyanosis |
J:97230
|
|
domed cranium |
J:97230
|
|
neonatal lethality, complete penetrance |
J:97230
|
|
short limbs |
J:97230
|
Gnastm3Lsw/Gnastm3Lsw
Tg(TPO-cre)1Shk/0
involves: 129S6/SvEvTac * FVB/NCr
|
normal
endocrine/exocrine gland phenotype |
J:168249
|
Gnastm4Lsw/Gnas+
involves: 129S6/SvEvTac
|
abnormal blood homeostasis |
J:233851
|
|
abnormal kidney morphology |
J:233851
|
Gnastm4Lsw/Gnas+
involves: 129S6/SvEvTac * Black Swiss * CD-1
|
abnormal adipose tissue morphology |
J:99237
|
|
abnormal glucose homeostasis |
J:99237
|
|
decreased oxygen consumption |
J:99237
|
|
edema |
J:99237
|
|
impaired glucose tolerance |
J:99237
|
|
increased brown adipose tissue amount |
J:99237
|
|
increased circulating glucose level |
J:99237
|
|
increased circulating insulin level |
J:99237
|
|
increased circulating leptin level |
J:99237
|
|
increased circulating triglyceride level |
J:99237
|
|
increased interscapular fat pad weight |
J:99237
|
|
increased total body fat amount |
J:99237
|
|
increased white adipose tissue amount |
J:99237
|
|
insulin resistance |
J:99237
|
|
obese |
J:99237
|
|
paternal imprinting |
J:99237
|
|
postnatal lethality, incomplete penetrance |
J:99237
|
Gnastm4Lsw/Gnastm4Lsw
involves: 129S6/SvEvTac * Black Swiss * CD-1
|
prenatal lethality |
J:99237
|
Gnastm5.1Lsw/Gnastm5.1Lsw
H2az2Tg(Wnt1-cre)11Rth/H2az2+
involves: 129S6/SvEvTac * C57BL/6J * CBA/J
|
abnormal bone ossification |
J:254756
|
|
abnormal craniofacial bone morphology |
J:254756
|
|
abnormal craniofacial morphology |
J:254756
|
|
abnormal hyoid bone body morphology |
J:254756
|
|
abnormal hyoid bone morphology |
J:254756
|
|
abnormal incisor morphology |
J:254756
|
|
abnormal mandible morphology |
J:254756
|
|
abnormal maxilla morphology |
J:254756
|
|
abnormal nasal septum cartilage morphology |
J:254756
|
|
abnormal premaxilla morphology |
J:254756
|
|
abnormal suckling behavior |
J:254756
|
|
abnormal sympathetic ganglion morphology |
J:254756
|
|
abnormal thyroid cartilage morphology |
J:254756
|
|
abnormal tongue morphology |
J:254756
|
|
abnormal tympanic ring morphology |
J:254756
|
|
absent mandibular angle |
J:254756
|
|
absent mandibular condyloid process |
J:254756
|
|
absent mandibular coronoid process |
J:254756
|
|
absent nasal capsule |
J:254756
|
|
normal
cardiovascular system phenotype |
J:254756
|
|
complete cleft palate |
J:254756
|
|
cyanosis |
J:254756
|
|
domed cranium |
J:254756
|
|
normal
embryo phenotype |
J:254756
|
|
mandible hypoplasia |
J:254756
|
|
maxilla hypoplasia |
J:254756
|
|
neonatal lethality, complete penetrance |
J:254756
|
|
normal
nervous system phenotype |
J:254756
|
|
ocular hypertelorism |
J:254756
|
|
palatal shelves fail to meet at midline |
J:254756
|
|
palate bone hypoplasia |
J:254756
|
|
premature bone ossification |
J:254756
|
|
premature metopic suture closure |
J:254756
|
|
protruding tongue |
J:254756
|
|
respiratory distress |
J:254756
|
|
round face |
J:254756
|
|
short mandible |
J:254756
|
|
short maxilla |
J:254756
|
|
short snout |
J:254756
|
|
small dorsal root ganglion |
J:254756
|
Gnastm5.1Lsw/Gnastm5.1Lsw
Tg(Alb1-cre)1Dlr/?
involves: 129S6/SvEvTac * Black Swiss * FVB/N
|
abnormal energy expenditure |
J:102504
|
|
decreased circulating insulin level |
J:102504
|
|
decreased total body fat amount |
J:102504
|
|
normal
homeostasis/metabolism phenotype |
J:102504
|
|
hypoglycemia |
J:102504
|
|
improved glucose tolerance |
J:102504
|
|
increased circulating glucagon level |
J:102504
|
|
increased circulating triglyceride level |
J:102504
|
|
increased liver glycogen level |
J:102504
|
|
increased liver weight |
J:102504
|
|
increased pancreas weight |
J:102504
|
|
pancreatic islet hyperplasia |
J:102504
|
Gnastm5.1Lsw/Gnastm5.1Lsw
Tg(Fabp4-cre)1Abel/0
involves: FVB
|
abnormal adipose tissue development |
J:159612
|
|
abnormal urine catecholamine level |
J:159612
|
|
abnormal white adipose tissue physiology |
J:159612
|
|
decreased body fat mass |
J:159612
|
|
decreased body length |
J:159612
|
|
decreased body size |
J:159612
|
|
decreased body weight |
J:159612
|
|
decreased circulating free fatty acids level |
J:159612
|
|
decreased circulating insulin level |
J:159612
|
|
decreased circulating leptin level |
J:159612
|
|
decreased circulating triglyceride level |
J:159612
|
|
decreased epididymal fat pad weight |
J:159612
|
|
decreased inguinal fat pad weight |
J:159612
|
|
decreased liver triglyceride level |
J:159612
|
|
decreased locomotor activity |
J:159612
|
|
decreased mesenteric fat pad weight |
J:159612
|
|
decreased renal fat pad weight |
J:159612
|
|
decreased skeletal muscle triglyceride level |
J:159612
|
|
decreased subcutaneous adipose tissue amount |
J:159612
|
|
decreased susceptibility to diet-induced obesity |
J:159612
|
|
decreased white adipose tissue amount |
J:159612
|
|
decreased white fat cell size |
J:159612
|
|
normal
homeostasis/metabolism phenotype |
J:159612
|
|
hypoglycemia |
J:159612
|
|
impaired adaptive thermogenesis |
J:159612
|
|
improved glucose tolerance |
J:159612
|
|
increased circulating corticosterone level |
J:159612
|
|
increased energy expenditure |
J:159612
|
|
increased fatty acid oxidation |
J:159612
|
|
increased insulin sensitivity |
J:159612
|
|
increased lean body mass |
J:159612
|
|
premature death |
J:159612
|
Gnastm5.1Lsw/Gnastm5.1Lsw
Tg(Gfy-cre)1Yyos/?
involves: 129S6/SvEvTac * Black Swiss * C57BL/6J * FVB/N
|
normal
taste/olfaction phenotype |
J:233447
|
Gnastm5.1Lsw/Gnastm5.1Lsw
Tg(Nes-cre)1Atp/0
involves: 129S6/SvEvTac * FVB/N
|
normal
craniofacial phenotype |
J:254756
|
Gnastm5.1Lsw/Gnastm5.1Lsw
Tg(Slc5a2-cre)1Tauc/0
involves: C57BL/6 * DBA/2
|
abnormal blood homeostasis |
J:233851
|
|
abnormal urine homeostasis |
J:233851
|
|
decreased circulating calcium level |
J:233851
|
|
decreased vitamin D level |
J:233851
|
|
increased circulating parathyroid hormone level |
J:233851
|
Tg(Camk2a-tTA)1Mmay/0
Tg(tetO-Gnas)1593Mpke/0
B6.Cg-Tg(Camk2a-tTA)1Mmay Tg(tetO-Gnas)1593Mpke
|
abnormal dorsal striatum morphology |
J:166114
|
|
abnormal spatial learning |
J:166114
|
|
abnormal ventral striatum morphology |
J:166114
|
|
normal
behavior/neurological phenotype |
J:166114
|
|
decreased prepulse inhibition |
J:166114
|
|
enhanced long-term potentiation |
J:166114
|
|
enhanced paired-pulse facilitation |
J:166114
|
|
enlarged lateral ventricles |
J:166114
|
|
hyperactivity |
J:166114
|
|
impaired contextual conditioning behavior |
J:166114
|
|
impaired spatial working memory |
J:166114
|
Excel File
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