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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Bcl2l11
BCL2-like 11 (apoptosis facilitator)
MGI:1197519
102 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Atmintm1.1Jhh/Atmintm1.1Jhh
Bcl2l11tm1.1Ast/Bcl2l11tm1.1Ast
Cd79atm1(cre)Reth/Cd79a+
Tg(IghMyc)22Bri/0
B6.Cg-Bcl2l11tm1.1Ast Cd79atm1(Cre)Reth Atmintm1.1Jhh Tg(IghMyc)22Bri 		increased lymphoma incidence J:230105
Atmintm1.2Jhh/Atmintm1.2Jhh
Bcl2l11tm1.1Ast/Bcl2l11tm1.1Ast
Cd79atm1(cre)Reth/Cd79a+
involves: 129S1/Sv * BALB/c * C57BL/6 		enlarged spleen J:191832
normal immune system phenotype J:191832
increased B cell number J:191832
increased immature B cell number J:191832
increased pre-B cell number J:191832
increased spleen weight J:191832
Baxtm1Sjk/Baxtm1Sjk
Bcl2l11tm1.1Ast/Bcl2l11tm1.1Ast
B6.129-Bcl2l11tm1.1Ast Baxtm1Sjk 		abnormal seminiferous tubule epithelium morphology J:103605
arrest of male meiosis J:103605
azoospermia J:103605
male infertility J:103605
small seminiferous tubules J:103605
Bcl2tm1Dlo/Bcl2tm1Dlo
Bcl2l11tm1.1Ast/Bcl2l11+
B6.129-Bcl2tm1Dlo Bcl2l11tm1.1Ast 		abnormal coat/hair pigmentation J:73316
abnormal hair follicle melanocyte morphology J:73316
abnormal lymphocyte physiology J:73316
absent hair follicle melanin granules J:73316
diluted coat color J:73316
normal hearing/vestibular/ear phenotype J:73316
increased T cell apoptosis J:73316
normal mortality/aging J:73316
normal renal/urinary system phenotype J:73316
Bcl2tm1Dlo/Bcl2tm1Dlo
Bcl2l11tm1.1Ast/Bcl2l11+
B6.Cg-Bcl2tm1Dlo Bcl2l11tm1.1Ast 		increased leukocyte cell number J:153846
increased spleen weight J:153846
Bcl2tm1Dlo/Bcl2tm1Dlo
Bcl2l11tm1.1Ast/Bcl2l11tm1.1Ast
B6.129-Bcl2tm1Dlo Bcl2l11tm1.1Ast 		abnormal leukopoiesis J:73316
abnormal lymphocyte physiology J:73316
decreased B cell apoptosis J:73316
normal hearing/vestibular/ear phenotype J:73316
increased T cell apoptosis J:73316
normal integument phenotype J:73316
normal mortality/aging J:73316
normal renal/urinary system phenotype J:73316
Bcl2tm1Dlo/Bcl2tm1Dlo
Bcl2l11tm1.1Ast/Bcl2l11tm1.1Ast
B6.Cg-Bcl2tm1Dlo Bcl2l11tm1.1Ast 		increased leukocyte cell number J:153846
increased spleen weight J:153846
Bcl2tm1Dlo/Bcl2tm1Dlo
Bcl2l11tm1.1Boui/Bcl2l11tm1.1Boui
B6.Cg-Bcl2tm1Dlo Bcl2l11tm1.1Boui 		diluted coat color J:153846
normal growth/size/body region phenotype J:153846
normal hematopoietic system phenotype J:153846
normal immune system phenotype J:153846
normal renal/urinary system phenotype J:153846
Bcl2tm1Dlo/Bcl2tm1Dlo
Bcl2l11tm1.1Boui/Bcl2l11tm2.1Boui
B6.Cg-Bcl2tm1Dlo Bcl2l11tm1.1Boui/Bcl2l11tm2.1Boui 		normal hematopoietic system phenotype J:153846
normal immune system phenotype J:153846
increased leukocyte cell number J:153846
increased spleen weight J:153846
normal renal/urinary system phenotype J:153846
Bcl2tm1Dlo/Bcl2tm1Dlo
Bcl2l11tm2.1Boui/Bcl2l11tm2.1Boui
B6.Cg-Bcl2tm1Dlo Bcl2l11tm2.1Boui 		diluted coat color J:153846
normal growth/size/body region phenotype J:153846
normal hematopoietic system phenotype J:153846
normal immune system phenotype J:153846
normal renal/urinary system phenotype J:153846
Bcl2tm1Dlo/Bcl2tm1Dlo
Bcl2l11tm3.1Boui/Bcl2l11tm3.1Boui
B6.Cg-Bcl2tm1Dlo Bcl2l11tm3.1Boui 		decreased splenocyte apoptosis J:153846
normal hematopoietic system phenotype J:153846
normal immune system phenotype J:153846
increased leukocyte cell number J:153846
increased spleen weight J:153846
polycystic kidney J:153846
postnatal growth retardation J:153846
premature death J:153846
Bcl2l11em1Flv/Bcl2l11+
Morrbidem1Flv/Morrbid+
C57BL/6N-Bcl2l11em1Flv Morrbidem1Flv /+ + 		normal immune system phenotype J:236609
Bcl2l11em1Flv/Bcl2l11+
Morrbid+/Morrbidem1Flv
C57BL/6N-Bcl2l11em1Flv +/+ Morrbidem1Flv 		decreased eosinophil cell number J:236609
decreased Ly6C high monocyte number J:236609
decreased neutrophil cell number J:236609
Bcl2l11tm1.1Ast/Bcl2l11+
Ptentm1Hwu/Pten+
Tg(CD2-icre)4Kio/0
involves: 129S1/Sv * 129S4/SvJae * C57BL/10 * CBA/Ca 		abnormal T cell number J:133215
increased germinal center B cell number J:133215
Bcl2l11tm1.1Ast/Bcl2l11+
Bmftm1Rjd/Bmf+
B6.129S-Bcl2l11tm1.1Ast Bmftm1Rjd 		decreased body weight J:153652
Bcl2l11tm1.1Ast/Bcl2l11tm1.1Ast
Biktm1Ast/Biktm1Ast
B6.Cg-Bcl2l11tm1.1Ast Biktm1Ast 		abnormal B cell differentiation J:103605
abnormal lymphocyte physiology J:103605
abnormal seminiferous tubule morphology J:103605
abnormal spermatogenesis J:103605
abnormal T cell differentiation J:103605
arrest of male meiosis J:103605
azoospermia J:103605
decreased body weight J:103605
decreased immature B cell number J:103605
decreased pre-B cell number J:103605
decreased pro-B cell number J:103605
decreased testis weight J:103605
enlarged spleen J:103605
increased B cell number J:103605
increased granulocyte number J:103605
increased mature B cell number J:103605
increased monocyte cell number J:103605
increased T cell number J:103605
male infertility J:103605
multinucleated giant male germ cells J:103605
Bcl2l11tm1.1Ast/Bcl2l11tm1.1Ast
Bmftm1Rjd/Bmftm1Rjd
B6.129S-Bcl2l11tm1.1Ast Bmftm1Rjd 		decreased body weight J:153652
decreased T cell apoptosis J:153652
hydrometrocolpos J:153652
increased B cell number J:153652
increased CD4-positive, alpha beta T cell number J:153652
increased CD8-positive, alpha-beta T cell number J:153652
increased splenocyte number J:153652
increased thymocyte number J:153652
interdigital webbing J:153652
postnatal lethality, incomplete penetrance J:153652
vagina atresia J:153652
Bcl2l11tm1.1Ast/Bcl2l11tm1.1Ast
Bmftm2.1Rjd/Bmftm2.1Rjd
B6.129S-Bcl2l11tm1.1Ast Bmftm2.1Rjd 		increased B cell number J:153652
increased CD4-positive, alpha beta T cell number J:153652
increased CD8-positive, alpha-beta T cell number J:153652
increased splenocyte number J:153652
Bcl2l11tm1.1Ast/Bcl2l11tm1.1Ast
Bnip3lGt(XT0573)Wtsi/Bnip3lGt(XT0573)Wtsi
involves: 129S1/Sv * C57BL/6 		decreased erythrocyte cell number J:137609
decreased lymphocyte cell number J:137609
Bcl2l11tm1.1Ast/Bcl2l11tm1.1Ast
Dicer1tm1Mmk/Dicer1tm1Mmk
Cd79atm1(cre)Reth/Cd79a+
involves: 129S1/Sv * BALB/c 		decreased B cell number J:135783
decreased mature B cell number J:135783
Bcl2l11tm1.1Ast/Bcl2l11tm1.1Ast
Faslpr/Faslpr
B6.Cg-Bcl2l11tm1.1Ast Faslpr 		abnormal effector T cell morphology J:132217
abnormal glomerular capillary morphology J:132217
abnormal kidney morphology J:132217
abnormal lymph node cell ratio J:132217
abnormal renal glomerulus basement membrane morphology J:132217
abnormal renal glomerulus morphology J:132217
abnormal splenic cell ratio J:132217
abnormal T cell number J:132217
abnormal T cell subpopulation ratio J:132217
decreased B cell number J:132217
decreased spleen red pulp amount J:132217
enlarged lymph nodes J:132217
enlarged spleen J:132217
expanded mesangial matrix J:132217
increased anti-double stranded DNA antibody level J:132217
increased anti-histone antibody level J:132217
increased anti-nuclear antigen antibody level J:132217
increased anti-single stranded DNA antibody level J:132217
increased autoantibody level J:132217
increased dendritic cell number J:132217
increased follicular B cell number J:132217
increased immature B cell number J:132217
increased kidney cell proliferation J:132217
increased leukocyte cell number J:132217
increased macrophage cell number J:132217
increased marginal zone B cell number J:132217
increased memory T cell number J:132217
increased renal glomerulus apoptosis J:132217
increased renal glomerulus basement membrane thickness J:132217
increased spleen white pulp amount J:132217
increased susceptibility to autoimmune disorder J:132217
increased transitional stage B cell number J:132217
lymph node hyperplasia J:132217
renal glomerulus hypertrophy J:132217
spleen hyperplasia J:132217
Bcl2l11tm1.1Ast/Bcl2l11tm1.1Ast
Gata1tm1.1Yen/Gata1tm1.1Yen
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N 		decreased erythroid progenitor cell number J:200716
Bcl2l11tm1.1Ast/Bcl2l11tm1.1Ast
Il15tm1Imx/Il15tm1Imx
involves: C57BL/6 		normal immune system phenotype J:208318
Bcl2l11tm1.1Ast/Bcl2l11tm1.1Ast
Mirc14tm1.2Flv/Mirc14tm1.2Flv
involves: 129S1/Sv * C57BL/6 * C57BL/6N * FVB/N * SJL 		decreased NK T cell number J:203157
Bcl2l11tm1.1Ast/Bcl2l11tm1.1Ast
Mlf1tm1Swm/Mlf1tm1Swm
involves: 129S1/Sv * C57BL/6 		decreased splenocyte apoptosis J:266833
decreased thymocyte apoptosis J:266833
Bcl2l11tm1.1Ast/Bcl2l11tm1.1Ast
Pmaip1tm1Ast/Pmaip1tm1Ast
involves: 129S1/Sv * C57BL/6 		abnormal NK cell morphology J:123409
Bcl2l11tm1.1Ast/Bcl2l11tm1.1Ast
Zbtb1m1Btlr/Zbtb1m1Btlr
involves: 129S1/Sv * C3H/HeN * C57BL/6 * C57BL/6J 		absent T cells J:178820
Bcl2l11tm1.1Boui/Bcl2l11+
Tg(IghMyc)22Bri/0
involves: C57BL/6 * SJL 		increased B cell derived lymphoma incidence J:186117
increased leukocyte cell number J:186117
increased T cell derived lymphoma incidence J:186117
premature death J:186117
Bcl2l11tm1.1Boui/Bcl2l11tm1.1Boui
Tg(IghMyc)22Bri/0
involves: C57BL/6 * SJL 		increased B cell derived lymphoma incidence J:186117
increased leukocyte cell number J:186117
premature death J:186117
Bcl2l11tm1Ast/Bcl2l11tm1Ast
Dicer1tm1Bdh/Dicer1tm1Bdh
Aicdatm1(cre)Njen/Aicda+
involves: 129S1/Sv * C57BL/6 		abnormal B cell differentiation J:181782
decreased germinal center B cell number J:181782
decreased plasma cell number J:181782
Bcl2l11tm2.1Boui/Bcl2l11+
Tg(IghMyc)22Bri/0
involves: C57BL/6 * SJL 		increased B cell derived lymphoma incidence J:186117
increased leukocyte cell number J:186117
premature death J:186117
Bcl2l11tm2.1Boui/Bcl2l11tm2.1Boui
Tg(IghMyc)22Bri/0
involves: C57BL/6 * SJL 		increased B cell derived lymphoma incidence J:186117
increased leukocyte cell number J:186117
premature death J:186117
Bcl2l11tm3.1Boui/Bcl2l11+
Tg(IghMyc)22Bri/0
involves: C57BL/6 * SJL 		increased B cell derived lymphoma incidence J:186117
premature death J:186117
Bcl2l11tm3.1Boui/Bcl2l11tm3.1Boui
Tg(IghMyc)22Bri/0
involves: C57BL/6 * SJL 		increased B cell derived lymphoma incidence J:186117
premature death J:186117
Bcl2l11tm3Rjd/Bcl2l11tm3Rjd
Bmftm3.1Rjd/Bmftm3.1Rjd
B6.129S6-Bcl2l11tm3Rjd Bmftm3.1Rjd 		increased B cell number J:153652
increased CD4-positive, alpha beta T cell number J:153652
increased CD8-positive, alpha-beta T cell number J:153652
increased splenocyte number J:153652
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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02/04/2020
MGI 6.14 		The Jackson Laboratory