ApcMin/Apc+
Pla2g2aMom1-r/?
Prkdcdxnph/Prkdcdxnph
involves: BALB/cByJ * C57BL/6
|
increased incidence of tumors by ionizing radiation induction |
J:83497
|
B2mtm1Unc/B2mtm1Unc
Emv30b/Emv30b
Prkdcscid/Prkdcscid
Tg(B2M)55Hpl/?
Mcph1Tg(HLA-A2.1)1Enge/?
NOD.Cg-B2mtm1Unc Mcph1Tg(HLA-A2.1)1Enge Emv30b Prkdcscid Tg(B2M)55Hpl/Dvs
|
decreased susceptibility to autoimmune diabetes |
J:109851
|
B2mtm1Unc/B2mtm1Unc
Prkdcscid/Prkdcscid
NOD.Cg-B2mtm1Unc Prkdcscid
|
abnormal NK cell physiology |
J:102141
|
|
abnormal response to transplant |
J:102141
|
|
absent lymphocyte |
J:102141
|
|
arrested B cell differentiation |
J:102141
|
|
arrested T cell differentiation |
J:102141
|
|
decreased level of surface class I molecules |
J:102141
|
|
increased liver iron level |
J:102141
|
|
increased macrophage cell number |
J:102141
|
|
increased T cell derived lymphoma incidence |
J:102141
|
|
premature death |
J:102141
|
Dmdmdx/Dmdmdx
Prkdcscid/Prkdcscid
involves: BALB/c * C57BL/10ScSn * C57BL/Ka
|
abnormal vertebral column morphology |
J:125527
|
|
absent CD4-positive, alpha-beta T cells |
J:125527
|
|
absent CD8-positive, alpha-beta T cells |
J:125527
|
|
centrally nucleated skeletal muscle fibers |
J:125527
|
|
decreased B cell number |
J:125527
|
|
decreased transforming growth factor beta level |
J:125527
|
|
impaired exercise endurance |
J:125527
|
|
impaired skeletal muscle contractility |
J:125527
|
|
increased skeletal muscle fiber diameter |
J:125527
|
|
reduced fertility |
J:125527
|
|
skeletal muscle fiber degeneration |
J:125527
|
|
skeletal muscle fibrosis |
J:125527
|
Dxmod/Dxmod
Prkdcdxnph/Prkdcdxnph
involves: BALB/cJ * 129X1/SvJ
|
dilated renal tubule |
J:96632
|
|
glomerulosclerosis |
J:96632
|
Emv30b/Emv30b
Prkdcscid/Prkdcscid
NOD.Cg-Emv30b Prkdcscid/Dvs
|
increased T cell derived lymphoma incidence |
J:29951
|
Emv30b/Emv30b
Prkdcscid/Prkdcscid
Tg(IghH280)48Dvs/?
Tg(IgkH280)934Dvs/?
NOD.Cg-Emv30b Prkdcscid Tg(IghH280)48Dvs Tg(IgkH280)934Dvs/Dvs
|
normal
homeostasis/metabolism phenotype |
J:274578
|
Ightm2Cgn/Igh+
Igktm2Rsky/Igk+
Prkdcscid/Prkdcscid
involves: 129P2/OlaHsd * BALB/c * C57BL/Ka
|
abnormal class switch recombination |
J:150435
|
Il2rgtm1Wjl/Il2rgtm1Wjl
Prkdcscid/Prkdcscid
NOD.Cg-Prkdcscid Il2rgtm1Wjl/Sz
|
abnormal glucose homeostasis |
J:138005
|
|
abnormal immune system organ morphology |
J:109833
|
|
abnormal response to transplant |
J:109833
|
|
abnormal splenic cell ratio |
J:109833
|
|
abnormal thymus morphology |
J:109833
|
|
decreased CD4-positive, alpha-beta T cell number |
J:109833
|
|
decreased CD8-positive, alpha-beta T cell number |
J:109833
|
|
decreased immature B cell number |
J:109833
|
|
decreased immunoglobulin level |
J:109833
|
|
decreased incidence of tumors by ionizing radiation induction |
J:109833
|
|
decreased leukocyte cell number |
J:109833
|
|
decreased mature B cell number |
J:109833
|
|
decreased mean corpuscular volume |
J:109833
|
|
decreased NK cell number |
J:109833
|
|
decreased spleen B cell follicle number |
J:109833
|
|
hyperglycemia |
J:138005
|
|
increased cellular sensitivity to X-ray irradiation |
J:109833
|
|
lymph node hypoplasia |
J:109833
|
|
premature death |
J:109833
|
|
small lymph nodes |
J:109833
|
|
thymus cyst |
J:109833
|
Il2rgtm1Wjl/Y
Prkdcscid/Prkdcscid
NOD.Cg-Prkdcscid Il2rgtm1Wjl/Sz
|
abnormal immune system organ morphology |
J:109833
|
|
abnormal response to transplant |
J:109833,
J:140388
|
|
abnormal splenic cell ratio |
J:109833
|
|
abnormal thymus morphology |
J:109833
|
|
decreased CD4-positive, alpha-beta T cell number |
J:109833
|
|
decreased CD8-positive, alpha-beta T cell number |
J:109833
|
|
decreased immature B cell number |
J:109833
|
|
decreased immunoglobulin level |
J:109833
|
|
decreased leukocyte cell number |
J:109833
|
|
decreased mature B cell number |
J:109833
|
|
decreased mean corpuscular volume |
J:109833
|
|
decreased NK cell number |
J:109833
|
|
decreased spleen B cell follicle number |
J:109833
|
|
increased cellular sensitivity to X-ray irradiation |
J:109833
|
|
lymph node hypoplasia |
J:109833
|
|
premature death |
J:109833
|
|
small lymph nodes |
J:109833
|
Lystbg-J/Lystbg-J
Prkdcscid/Prkdcscid
B6.Cg-Lystbg-J Prkdcscid/Sz
|
abnormal complement pathway |
J:34814
|
|
abnormal granulocyte morphology |
J:34814
|
|
abnormal level of surface class II molecules |
J:34814
|
|
abnormal lymph node morphology |
J:34814
|
|
abnormal neutrophil morphology |
J:34814
|
|
abnormal Peyer's patch morphology |
J:34814
|
|
abnormal spleen white pulp morphology |
J:34814
|
|
abnormal thymus morphology |
J:34814
|
|
decreased B cell number |
J:34814
|
|
decreased CD4-positive, alpha-beta T cell number |
J:34814
|
|
decreased CD8-positive, alpha-beta T cell number |
J:34814
|
|
decreased immunoglobulin level |
J:34814
|
|
decreased lymphocyte cell number |
J:34814
|
|
decreased pre-B cell number |
J:34814
|
|
decreased T cell number |
J:34814
|
|
impaired natural killer cell mediated cytotoxicity |
J:34814
|
|
increased eosinophil cell number |
J:34814
|
|
increased granulocyte number |
J:34814
|
|
increased macrophage cell number |
J:34814
|
|
increased monocyte cell number |
J:34814
|
|
increased neutrophil cell number |
J:34814
|
|
increased NK cell number |
J:34814
|
|
small Peyer's patches |
J:34814
|
|
small thymus |
J:34814
|
|
spleen hypoplasia |
J:34814
|
|
thymus cyst |
J:34814
|
Lystbg/Lystbg
Prkdcscid/Prkdcscid
Not Specified
|
increased susceptibility to infection |
J:4752
|
Prkdcscid/Prkdc+
Trp53tm1Tyj/Trp53tm1Tyj
involves: 129S2/SvPas * C57BL/6J
|
increased thymoma incidence |
J:47667
|
|
premature death |
J:47667
|
Prkdcscid/Prkdc+
Tg(LPV-TAg1135)11Tvd/0
involves: C57BL/6J * DBA/2J
|
increased thymoma incidence |
J:47667
|
|
premature death |
J:47667
|
Prkdcscid/Prkdcscid
Gnrh1hpg/Gnrh1hpg
STOCK Prkdcscid Gnrh1hpg/Bm
|
abnormal circulating protein level |
J:138840
|
|
absent seminal vesicle |
J:138840
|
|
decreased circulating testosterone level |
J:138840
|
|
decreased kidney weight |
J:138840
|
|
decreased liver weight |
J:138840
|
|
decreased tumor incidence |
J:14443,
J:138840
|
|
small salivary gland |
J:138840
|
Prkdcscid/Prkdcscid
Iduatm1Clk/Idua+
NOD.Cg-Prkdcscid Iduatm1Clk/J
|
broad head |
J:139626
|
|
enophthalmos |
J:139626
|
|
rough coat |
J:139626
|
|
short snout |
J:139626
|
|
small ears |
J:139626
|
Prkdcscid/Prkdcscid
Iduatm1Clk/Iduatm1Clk
NOD.Cg-Prkdcscid Iduatm1Clk/J
|
abnormal brain morphology |
J:139626
|
|
abnormal brainstem morphology |
J:139626
|
|
abnormal cerebellar cortex morphology |
J:139626
|
|
abnormal cerebellum morphology |
J:139626
|
|
abnormal hippocampus morphology |
J:139626
|
|
abnormal homeostasis |
J:139626
|
|
abnormal motor learning |
J:139626
|
|
abnormal striatum morphology |
J:139626
|
|
abnormal zygomatic bone morphology |
J:139626
|
|
broad head |
J:139626
|
|
enophthalmos |
J:139626
|
|
female infertility |
J:139626
|
|
impaired coordination |
J:139626
|
|
increased urine glycosaminoglycan level |
J:139626
|
|
pup cannibalization |
J:139626
|
|
rough coat |
J:139626
|
|
short snout |
J:139626
|
|
small ears |
J:139626
|
Prkdcscid/Prkdcscid
Mcph1Tg(HLA-A2.1)1Enge/Mcph1+
NOD.Cg-Mcph1Tg(HLA-A2.1)1Enge Prkdcscid/Dvs
|
abnormal splenocyte morphology |
J:91764
|
Prkdcscid/Prkdcscid
Rasa3scat/Rasa3scat
involves: BALB/c * BALB/cBy * C57BL
|
abnormal hematopoietic system morphology/development |
J:186485
|
|
abnormal immune system morphology |
J:186485
|
Prkdcscid/Prkdcscid
Sst1C57BL/6J/Sst1C57BL/6J
involves: C3HeB/FeJ * C57BL/6J
|
decreased susceptibility to bacterial infection |
J:93705
|
Prkdcscid/Prkdcscid
Tg(B2M)55Hpl/0
Mcph1Tg(HLA-A2.1)1Enge/Mcph1+
NOD.Cg-Mcph1Tg(HLA-A2.1)1Enge Prkdcscid Tg(B2M)55Hpl/Sz
|
abnormal response to transplant |
J:91764
|
|
increased circulating glucose level |
J:91764
|
Prkdcscid/Prkdcscid
Tg(CSF2)2Ygy/0
Tg(IL3)1Ygy/0
CB17.Cg-Prkdcscid Tg(CSF2)2Ygy Tg(IL3)1Ygy
|
abnormal response to transplant |
J:94302
|
Prkdcscid/Prkdcscid
Tg(CSF2)2Ygy/0
Tg(IL3)1Ygy/0
Tg(KITLG)3Ygy/0
CB17.Cg-Prkdcscid Tg(CSF2)2Ygy Tg(IL3)1Ygy Tg(KITLG)3Ygy
|
abnormal response to transplant |
J:94302,
J:106416
|
Prkdcscid/Prkdcscid
Tg(CSF2)2Ygy/0
Tg(IL3)1Ygy/0
Tg(KITLG)3Ygy/0
NOD.Cg-Prkdcscid Tg(CSF2)2Ygy Tg(IL3)1Ygy Tg(KITLG)3Ygy
|
abnormal response to transplant |
J:107052
|
|
decreased susceptibility to graft versus host disease |
J:107052
|
Prkdcscid/Prkdcscid
Tg(HLA-DRA*0101,HLA-DRB1*0101)1Dmz/Tg(HLA-DRA*0101,HLA-DRB1*0101)1Dmz
NOD.Cg-Tg(HLA-DRA*0101,HLA-DRB1*0101)1Dmz Prkdcscid/Gck
|
abnormal professional antigen presenting cell morphology |
J:126700
|
|
absent T cells |
J:126700
|
|
extended life span |
J:126700
|
Prkdcscid/Prkdcscid
Tg(Ins2-Fasl)24Ach/0
NOD.Cg-Prkdcscid Tg(Ins2-Fasl)24Ach
|
decreased susceptibility to autoimmune diabetes |
J:81416
|
|
increased susceptibility to autoimmune diabetes |
J:81416
|
Prkdcscid/Prkdcscid
Tg(INS-HBEGF*L148S*P149T)70Rin/0
C.BKa-Prkdcscid Tg(INS-HBEGF*L148S*P149T)70Rin
|
abnormal pancreatic islet morphology |
J:204420
|
|
decreased circulating insulin level |
J:204420
|
|
decreased pancreatic beta cell number |
J:204420
|
|
hyperglycemia |
J:204420
|
Prkdcscid/Prkdcscid
Tg(INS-Il10)#Sar/0
NOD.Cg-Prkdcscid Tg(INS-Il10)#Sar
|
increased susceptibility to autoimmune diabetes |
J:66103
|
Prkdcscid/Prkdcscid
Tg(LPV-TAg1135)11Tvd/0
involves: C57BL/6J * DBA/2J
|
increased thymoma incidence |
J:47667
|
|
premature death |
J:47667
|
Prkdcscid/Prkdcscid
Tg(TcraAI4)1Dvs/0
Tg(TcrbAI4)1Dvs/0
NOD.Cg-Prkdcscid Tg(TcraAI4)1Dvs Tg(TcrbAI4)1Dvs
|
abnormal CD4-positive, alpha beta T cell morphology |
J:93553
|
|
increased susceptibility to autoimmune diabetes |
J:93553
|
Prkdcscid/Prkdcscid
Tg(Tcrb)93Vbo/0
involves: Balb/c * C57BL/Ka * C57BL/Lia * CBA/BrA
|
abnormal CD4-positive, alpha beta T cell morphology |
J:111476
|
|
abnormal CD8-positive, alpha beta T cell morphology |
J:111476
|
|
abnormal double-positive T cell morphology |
J:111476
|
|
abnormal single-positive T cell number |
J:111476
|
|
abnormal T cell differentiation |
J:111476
|
Prkdcscid/Prkdcscid
Tg(TcrLCMV)327Sdz/?
NOD.Cg-Emv30b Prkdcscid Tg(TcrLCMV)327Sdz/DvsJ
|
normal
immune system phenotype |
J:71050
|
Prkdcscid/Prkdcscid
Tgfb1tm1Doe/Tgfb1tm1Doe
involves: 129 * C3H * CF-1
|
abnormal spermatid morphology |
J:129629
|
|
abnormal spermatogenesis |
J:129629
|
|
decreased body size |
J:129629
|
|
decreased body weight |
J:129629
|
|
decreased circulating follicle stimulating hormone level |
J:129629
|
|
decreased circulating luteinizing hormone level |
J:129629
|
|
decreased circulating testosterone level |
J:129629
|
|
decreased retroperitoneal fat pad weight |
J:129629
|
|
decreased spleen weight |
J:129629
|
|
decreased testes secretion |
J:129629
|
|
failure of copulatory plug deposition |
J:129629
|
|
failure of ejaculation |
J:129629
|
|
increased lung weight |
J:129629
|
|
male infertility |
J:129629
|
|
oligozoospermia |
J:129629
|
|
reduced male mating frequency |
J:129629
|
|
normal
reproductive system phenotype |
J:129629
|
|
small seminiferous tubules |
J:129629
|
Prkdcscid/Prkdcscid
Trp53tm1Tyj/Trp53tm1Tyj
involves: 129S2/SvPas * C57BL/6J
|
decreased tumor incidence |
J:47667
|
|
premature death |
J:47667
|
Prkdctm1Get/Prkdc+
Rad54ltm1Jhjh/Rad54ltm1Jhjh
involves: 129P2/OlaHsd * C57BL/6
|
abnormal chromosome morphology |
J:84801
|
|
decreased telomere length |
J:84801
|
Prkdctm1Get/Prkdctm1Get
Rad54ltm1Jhjh/Rad54ltm1Jhjh
involves: 129P2/OlaHsd * C57BL/6
|
abnormal chromosome morphology |
J:84801
|
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