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Mamdc4 Gene Detail
Summary
  • Symbol
    Mamdc4
  • Name
    MAM domain containing 4
  • Synonyms
    LOC381352
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685841
    NCBI Gene: 381352
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:25563112-25572158 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 17.41 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    90 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2685841
protein coding gene Chr2:25563112-25574845 (-)
129S1/SvImJ MGP_129S1SvImJ_G0025455
protein coding gene Chr2:23463895-23475619 (-)
A/J MGP_AJ_G0025432
protein coding gene Chr2:22550376-22562076 (-)
AKR/J MGP_AKRJ_G0025402
protein coding gene Chr2:23320167-23331970 (-)
BALB/cJ MGP_BALBcJ_G0025428
protein coding gene Chr2:22672228-22684029 (-)
C3H/HeJ MGP_C3HHeJ_G0025189
protein coding gene Chr2:23248398-23261620 (-)
C57BL/6NJ MGP_C57BL6NJ_G0025872
protein coding gene Chr2:24203423-24215125 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0023283
protein coding gene Chr2:21462130-21473987 (-)
CAST/EiJ MGP_CASTEiJ_G0024652
protein coding gene Chr2:23117389-23129538 (-)
CBA/J MGP_CBAJ_G0025167
protein coding gene Chr2:25042479-25054087 (-)
DBA/2J MGP_DBA2J_G0025300
protein coding gene Chr2:22391828-22404326 (-)
FVB/NJ MGP_FVBNJ_G0025262
protein coding gene Chr2:22139780-22151517 (-)
LP/J MGP_LPJ_G0025386
protein coding gene Chr2:23401166-23415084 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0025293
protein coding gene Chr2:25238229-25249935 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0025931
protein coding gene Chr2:23260205-23272800 (-)
PWK/PhJ MGP_PWKPhJ_G0024400
protein coding gene Chr2:22213061-22225130 (-)
SPRET/EiJ MGP_SPRETEiJ_G0024200
protein coding gene Chr2:23405039-23416035 (-)
WSB/EiJ MGP_WSBEiJ_G0024721
protein coding gene Chr2:23331325-23343052 (-)



Homology
more
  • Human Ortholog
    MAMDC4, MAM domain containing 4
  • Vertebrate Orthologs
    10
  • Human Ortholog
    MAMDC4, MAM domain containing 4
    Orthology source: HomoloGene, HGNC
  • Synonyms
    AEGP
  • Links
    NCBI Gene ID: 158056
    neXtProt AC: NX_Q6UXC1
    UniProt: Q6UXC1

  • Chr Location
    9q34.3; chr9:136852367-136860799 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 17102
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: MAMDC4
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype reference
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 381352 NCBI Gene Model | MGI Sequence Detail 9047 C57BL/6J ±  kb
transcript NM_001081199 RefSeq | MGI Sequence Detail 3990 C57BL/6  
polypeptide A2AJA7 UniProt | EBI | MGI Sequence Detail 1228 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000010097 apical endosomal glycoprotein
  • InterPro Domains
    IPR013320 Concanavalin A-like lectin/glucanase domain superfamily
    IPR036055 LDL receptor-like superfamily
    IPR023415 Low-density lipoprotein (LDL) receptor class A, conserved site
    IPR002172 Low-density lipoprotein (LDL) receptor class A repeat
    IPR000998 MAM domain
Molecular
Reagents
less

  • Microarray probesets 1
References
more
  • Summaries
    All 14
    Gene Ontology 3
    Phenotypes 1
  • Earliest
    J:23000 MGD Nomenclature Committee, 2/14/1995;
  • Latest
    J:155856 Mouse Genome Informatics Scientific Curators, Rat to Mouse ISO GO annotation transfer. 2010 Jan;

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
10/08/2019
MGI 6.14
The Jackson Laboratory