79 phenotypes from 11 alleles in 18 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cd207tm2.1(cre)Bjec/Cd207+ Tgfbr1tm1.1Karl/Tgfbr1tm1.1Karl involves: 129S4/SvJaeSor * C57BL/6	abnormal type IV hypersensitivity reaction	J:179630
	decreased dendritic cell number	J:179630
Gt(ROSA)26Sortm1(Tgfbr1*)Crm/Gt(ROSA)26Sor+ Tg(Col1a2-cre/ERT,-ALPP)7Cpd/0 involves: 129S7/SvEvBrd * C57BL/6 * DBA/2	abnormal artery morphology	J:134135
	abnormal blood vessel morphology	J:134135
	abnormal blood vessel physiology	J:134135
	abnormal dermal layer morphology	J:134135
	abnormal kidney arterial blood vessel morphology	J:134135
	abnormal lung vasculature morphology	J:134135
	abnormal skin condition	J:134135
	decreased body weight	J:134135
	decreased subcutaneous adipose tissue amount	J:134135
	renal interstitial fibrosis	J:134135
	sparse hair	J:134135
	thick dermal layer	J:134135
	thick skin	J:134135
	thin epidermis	J:134135
	vascular smooth muscle hypertrophy	J:134135
Hprt1tm1(CAG-Tgfbr1*)Lba/Hprt1tm1(CAG-Tgfbr1*)Lba Tg(Cd4-cre)1Cwi/0 involves: 129 * C57BL/6 * DBA/2	abnormal T cell activation	J:148747
Hprt1tm1(CAG-Tgfbr1*)Lba/Y Tg(Cd4-cre)1Cwi/0 involves: 129 * C57BL/6 * DBA/2	abnormal T cell activation	J:148747
Tg(Col2a1-cre/ERT2)1Dic/0 Tgfbr1tm1.1Karl/Tgfbr1tm1.1Karl involves: 129 * C57BL/6	abnormal articular cartilage morphology	J:271724
	abnormal synovial joint morphology	J:271724
	increased chondrocyte apoptosis	J:271724
	osteoarthritis	J:271724
	osteophytes	J:271724
Tgfbr1R244Q/Tgfbr1+ either: (involves: C57BL/6) or (involves: BALB/c * C57BL/6)	abnormal cartilage development	J:175236
	enhanced wound healing	J:175236
Tgfbr1R244Q/Tgfbr1R244Q either: (involves: C57BL/6) or (involves: BALB/c * C57BL/6)	abnormal cartilage development	J:175236
	enhanced wound healing	J:175236
Tgfbr1tm1.1Hcd/Tgfbr1+ 129S6(Cg)-Tgfbr1tm1.1Hcd	abnormal aorta bulb morphology	J:204960
	abnormal aorta elastic fiber morphology	J:204960
	abnormal aortic arch morphology	J:204960
	abnormal coronary artery morphology	J:204960
	aortic dissection	J:204960
	ascending aorta aneurysm	J:204960
	dilated aorta bulb	J:204960
	hemopericardium	J:204960
	hemothorax	J:204960
	increased aorta wall thickness	J:204960
	kyphosis	J:204960
	premature coronal suture closure	J:204960
	premature cranial suture closure	J:204960
	premature death	J:204960
	premature lambdoid suture closure	J:204960
Tgfbr1tm1.1Karl/Tgfbr1tm1.1Karl A1cfTg(Myh6-cre/Esr1*)1Jmk/A1cf+ involves: 129S/Sv * C57BL/6 * FVB/N	normal cardiovascular system phenotype	J:164749
	decreased cardiac muscle contractility	J:164749
	dilated cardiomyopathy	J:164749
	premature death	J:164749
Tgfbr1tm1.1Karl/Tgfbr1tm1.1Karl Tg(Acvrl1-cre)L1Spo/0 involves: 129 * FVB	normal cardiovascular system phenotype	J:130020
	no abnormal phenotype detected	J:130020
Tgfbr1tm1.1Karl/Tgfbr1tm1.1Karl Tg(Mx1-cre)1Cgn/0 involves: 129 * C57BL/6 * CBA	normal hematopoietic system phenotype	J:86262
	increased hematopoietic stem cell proliferation	J:86262
Tgfbr1tm1.1Karl/Tgfbr1tm1.1Karl Tg(Nes-cre)1Atp/0 involves: 129 * FVB/N	abnormal medial nasal prominence morphology	J:138715
	abnormal palatal shelf morphology	J:138715
	bilateral cleft upper lip	J:138715
	cleft upper lip	J:138715
	lethality throughout fetal growth and development, complete penetrance	J:138715
	maxillary prominence hypoplasia	J:138715
	palatal shelf hypoplasia	J:138715
	unilateral cleft upper lip	J:138715
Tgfbr1tm1.1Karl/Tgfbr1tm1.1Karl Tg(Tie1-cre)9Ref/0 either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ)	abnormal vitelline vasculature morphology	J:98373
	prenatal lethality, complete penetrance	J:98373
Tgfbr1tm1.1Vlcg/Tgfbr1tm1.1Vlcg involves: 129S6/SvEvTac * C57BL/6NTac	no abnormal phenotype detected	J:200671
Tgfbr1tm1Bopa/Tgfbr1tm1Bopa B6.129S1-Tgfbr1tm1Bopa	embryonic lethality, complete penetrance	J:143706
Tgfbr1tm1Dgen/Tgfbr1tm1Dgen involves: 129P2/OlaHsd * C57BL/6	preweaning lethality, complete penetrance	J:101679
Tgfbr1tm1Karl/Tgfbr1tm1.1Karl Tg(GATA5-cre)1Krc/0 involves: 129	abnormal bronchiole epithelium morphology	J:157922
	abnormal lung development	J:157922
	abnormal pulmonary alveolus morphology	J:157922
	abnormal skin development	J:157922
	decreased club cell number	J:157922
	dilated respiratory conducting tube	J:157922
	neonatal lethality, complete penetrance	J:157922
	small lung	J:157922
Tgfbr1tm1Karl/Tgfbr1tm1Karl Not Specified	abnormal angiogenesis	J:68770
	abnormal neural tube morphology	J:68770
	abnormal placenta labyrinth morphology	J:68770
	abnormal visceral yolk sac morphology	J:68770
	absent vitelline blood vessels	J:68770
	decreased embryo size	J:68770
	embryonic growth retardation	J:68770
	embryonic lethality during organogenesis, complete penetrance	J:68770
	kinked neural tube	J:68770
	pericardial effusion	J:68770
Tgfbr1tm1Mulm/Tgfbr1tm1Mulm involves: 129P2/OlaHsd	absent vitelline blood vessels	J:128498
	embryonic lethality during organogenesis, complete penetrance	J:128498
Tgfbr1tm1Spo/Tgfbr1tm1Spo either: (involves: 129S4/SvJae) or (involves: 129 * C57BL/6)	abnormal vascular smooth muscle morphology	J:104918
	abnormal vitelline vascular remodeling	J:104918
	embryonic growth retardation	J:104918
	embryonic lethality during organogenesis, complete penetrance	J:104918
	excessive folding of visceral yolk sac	J:104918