166 phenotypes from 16 alleles in 33 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Amhr2tm3(cre)Bhr/Amhr2+ Artm1Chc/Y involves: 129S/SvEv * C57BL/6	abnormal meiosis	J:118270
	abnormal seminiferous tubule morphology	J:118270
	arrest of male meiosis	J:118270
	arrest of spermatogenesis	J:118270
	azoospermia	J:118270
	decreased circulating testosterone level	J:118270
	male infertility	J:118270
	small seminiferous tubules	J:118270
	small testis	J:118270
Arem1Liuy/Y involves: C57BL/6J * CBA	secondary sex reversal	J:202050
	small testis	J:202050
ArTfm-Jms/Y involves: C57BL/6JJms	abnormal secondary sex determination	J:19298
	secondary sex reversal	J:19298
	small testis	J:19298
ArTfm-Jms/ArTfm-Jms involves: C57BL/6JJms	female infertility	J:19298
	increased body weight	J:19298
ArTfm/Y involves: NMRI * STOCK EdaTa Atp7aMo-blo	abnormal seminiferous tubule morphology	J:140803
	arrest of male meiosis	J:140803
	cryptorchism	J:140803
	enlarged seminiferous tubules	J:140803
	increased Leydig cell number	J:140803
	increased testis tumor incidence	J:140803
	secondary sex reversal	J:140803
ArTfm/Y involves: STOCK EdaTa Atp7aMo-blo	abnormal bone marrow cell number	J:110923
	abnormal erythropoiesis	J:110923
	abnormal myeloid leukocyte morphology	J:110923
	abnormal seminiferous tubule morphology	J:140803
	arrest of male meiosis	J:140803
	increased immature B cell number	J:110923
	secondary sex reversal	J:140803
ArTfm/Y Not Specified	abnormal adult Leydig cell differentiation	J:65900
	abnormal sensory neuron innervation pattern	J:192549
	abnormal spermatogenesis	J:65900
	abnormal testis morphology	J:65900
ArTfm/Y STOCK EdaTa Atp7aMo-blo/+ +	abnormal anogenital distance	J:5173
	abnormal female reproductive system morphology	J:5173
	abnormal gametogenesis	J:5173
	abnormal male reproductive system morphology	J:5173
	abnormal secondary sex determination	J:5173
	abnormal social/conspecific interaction behavior	J:5173
	absent epididymis	J:5173
	absent vas deferens	J:5173
	arrest of male meiosis	J:5173
	cryptorchism	J:5173
	Leydig cell hypertrophy	J:5173
	male pseudohermaphroditism	J:5173
	secondary sex reversal	J:5173
	small testis	J:5173
	vagina atresia	J:5173
Artm1.1Chc/Y involves: 129S/SvEv * C57BL/6 * FVB/N	abnormal tumor morphology	J:120844
	absent epididymis	J:89886
	absent prostate gland	J:89886
	absent seminal vesicle	J:89886
	arrest of spermatogenesis	J:89886
	decreased circulating testosterone level	J:89886
	decreased incidence of tumors by chemical induction	J:120844
	increased circulating luteinizing hormone level	J:89886
	preneoplasia	J:120844
	small testis	J:89886
Artm1.1Chc/Artm1.1Chc involves: 129S/SvEv * C57BL/6 * FVB/N	decreased incidence of tumors by chemical induction	J:120844
	preneoplasia	J:120844
Artm1.1Jdz/Y B6.129X1-Artm1.1Jdz	abnormal male reproductive system morphology	J:123057
	abnormal testis morphology	J:123057
	absent prostate gland	J:123057
	absent seminal vesicle	J:123057
	arrest of male meiosis	J:123057
	arrest of spermatogenesis	J:123057
	azoospermia	J:123057
	cryptorchism	J:123057
	decreased body weight	J:123057
	decreased circulating testosterone level	J:123057
	decreased male germ cell number	J:123057
	decreased testis weight	J:123057
	secondary sex reversal	J:123057
	small seminiferous tubules	J:123057
	small testis	J:123057
Artm1.1Jdz/Y involves: 129X1/SvJ * C57BL/6	abnormal testis morphology	J:122327
	absent epididymis	J:122327
	absent prostate gland	J:122327
	absent scrotum	J:122327
	absent seminal vesicle	J:122327
	cryptorchism	J:122327
	decreased circulating testosterone level	J:122327
	decreased testis weight	J:122327
	normal growth/size/body region phenotype	J:122327
	short perineum	J:122327
Artm1.1Reb/Y involves: 129S4/SvJaeSor * C57BL/6 * DBA/2J	arrest of male meiosis	J:90393
	cryptorchism	J:90393
	male pseudohermaphroditism	J:90393
	secondary sex reversal	J:90393
	small testis	J:90393
Artm1.1Verh/Y involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6	abnormal male reproductive system morphology	J:88169
	abnormal peritubular myoid cell morphology	J:88169
	abnormal postnatal growth	J:88169
	abnormal secondary sex determination	J:88169
	abnormal spermatogenesis	J:88169
	absent epididymis	J:88169
	absent seminal vesicle	J:88169, J:100799
	absent vas deferens	J:88169
	absent Wolffian ducts	J:88169
	azoospermia	J:88169
	cryptorchism	J:88169
	decreased Leydig cell number	J:100799
	decreased male germ cell number	J:88169
	decreased testis weight	J:88169, J:100799
	increased circulating luteinizing hormone level	J:100799
	increased male germ cell apoptosis	J:88169
	secondary sex reversal	J:88169
	small seminiferous tubules	J:88169
	small testis	J:88169
Artm1Chc/Y involves: 129S/SvEv * C57BL/6J	no abnormal phenotype detected	J:81789
Artm1Chc/Ar+ Tmem163Tg(ACTB-cre)2Mrt/0 involves: 129S/SvEv * C57BL/6J * FVB/N	decreased litter size	J:81789
Artm1Chc/Artm1.1Chc Tmem163Tg(ACTB-cre)2Mrt/0 involves: 129S/SvEv * C57BL/6J * FVB/N	abnormal branching of the mammary ductal tree	J:87193
	abnormal lactation	J:87193
	abnormal mammary gland morphology	J:87193
	abnormal nursing	J:87193
	decreased litter size	J:81789
	decreased ovary weight	J:87193
	decreased oviduct weight	J:87193
	decreased uterus weight	J:87193
	enlarged thymus	J:87193
Artm1Chc/Y Plekha5Tg(AMH-cre)1Flor/Plekha5+ involves: 129S/SvEv * C57BL/6 * SJL	abnormal meiosis	J:118270
	abnormal seminiferous tubule morphology	J:89886, J:118270
	abnormal spermatogenesis	J:89886
	arrest of male meiosis	J:89886, J:118270
	azoospermia	J:89886, J:118270
	decreased circulating testosterone level	J:89886, J:118270
	decreased male germ cell number	J:89886
	decreased testis weight	J:89886
	increased circulating follicle stimulating hormone level	J:89886
	increased circulating luteinizing hormone level	J:89886
	male infertility	J:89886, J:118270
	small testis	J:118270
Artm1Chc/Y Tg(Pbsn-cre)4Prb/0 involves: 129S/SvEv * C57BL/6 * DBA/2	abnormal prostate gland epithelium morphology	J:123402
	abnormal prostate gland morphology	J:123402
	enlarged prostate gland ventral lobe	J:123402
	normal homeostasis/metabolism phenotype	J:123402
	normal reproductive system phenotype	J:123402
Artm1Chc/Y Tg(Sycp1-cre)4Min/0 involves: 129S/SvEv * C57BL/6 * DBA/2	normal reproductive system phenotype	J:118270
Artm1Chc/Y Tmem163Tg(ACTB-cre)2Mrt/0 involves: 129S/SvEv * C57BL/6J * FVB/N	abnormal anogenital distance	J:81789
	abnormal external male genitalia morphology	J:81789
	abnormal fat cell morphology	J:81789, J:98775
	abnormal homeostasis	J:81789
	abnormal long bone metaphysis morphology	J:81789
	abnormal scrotum morphology	J:81789
	abnormal seminiferous tubule morphology	J:118270
	abnormal Sertoli cell morphology	J:81789, J:118270
	abnormal spermatocyte morphology	J:118270
	abnormal spermatogonia morphology	J:81789
	abnormal trabecular bone morphology	J:81789
	absent epididymis	J:81789
	absent external male genitalia	J:81789
	absent prostate gland	J:81789
	absent seminal vesicle	J:81789
	absent vas deferens	J:81789
	arrest of male meiosis	J:118270
	arrest of spermatogenesis	J:81789
	cryptorchism	J:81789, J:118270
	decreased adiponectin level	J:98775
	decreased body weight	J:81789, J:98775
	decreased circulating testosterone level	J:81789, J:98775, J:118270
	hyperglycemia	J:98775
	hypospadia	J:81789
	impaired glucose tolerance	J:98775
	increased bone ossification	J:81789
	increased circulating glucose level	J:98775
	increased circulating insulin level	J:98775
	increased circulating leptin level	J:98775
	increased circulating triglyceride level	J:98775
	increased gonadal fat pad weight	J:98775
	increased liver triglyceride level	J:98775
	increased osteoclast cell number	J:81789
	increased renal fat pad weight	J:98775
	increased skeletal muscle triglyceride level	J:98775
	increased susceptibility to weight gain	J:98775
	increased white adipose tissue amount	J:98775
	insulin resistance	J:98775
	Leydig cell hypertrophy	J:81789
	seminiferous tubule degeneration	J:118270
	small penis	J:81789
	small seminiferous tubules	J:118270
	small testis	J:118270
	testicular atrophy	J:98775
	testis hypoplasia	J:81789
Artm1Fcl/Y involves: 129S2/SvPas * C57BL/6	decreased epididymis weight	J:120102
	decreased germ cell number	J:120102
	decreased litter size	J:120102
	decreased prostate gland anterior lobe weight	J:120102
	decreased prostate gland ventral lobe weight	J:120102
	decreased seminal vesicle weight	J:120102
	decreased Sertoli cell number	J:120102
	decreased testis weight	J:120102
	reduced male fertility	J:120102
	small seminiferous tubules	J:120102
Artm1Fcl/Artm1Fcl involves: 129S2/SvPas * C57BL/6	no abnormal phenotype detected	J:120102
Artm1Jdz/Y B6.129X1-Artm1Jdz	no abnormal phenotype detected	J:123057
Artm1Jdz/Y Plekha5Tg(AMH-cre)1Flor/Plekha5+ involves: 129X1/SvJ * C57BL/6 * SJL	abnormal Leydig cell morphology	J:157337
	arrest of spermatogenesis	J:157337
	decreased testis weight	J:157337
	normal growth/size/body region phenotype	J:157337
	Leydig cell hypertrophy	J:157337
	male infertility	J:157337
	small seminiferous tubules	J:157337
Artm1Jdz/Y Plekha5Tg(AMH-cre)1Flor/Plekha5+ Tg(Abpa-cre)1Cmal/0 involves: 129X1/SvJ * C57BL/6 * DBA/2 * SJL	decreased testis weight	J:157337
Artm1Jdz/Y Plekha5Tg(AMH-cre)1Flor/Plekha5Tg(AMH-cre)1Flor involves: 129X1/SvJ * C57BL/6 * SJL	arrest of spermatogenesis	J:157337
	decreased testis weight	J:157337
	small seminiferous tubules	J:157337
Artm1Jdz/Y Tg(Abpa-cre)1Cmal/0 involves: 129X1/SvJ * C57BL/6 * DBA/2	abnormal Leydig cell morphology	J:157337
	abnormal spermatogenesis	J:157337
	decreased testis weight	J:157337
	normal growth/size/body region phenotype	J:157337
	Leydig cell hypertrophy	J:157337
	male infertility	J:157337
	small seminiferous tubules	J:157337
Artm1Jdz/Y Tg(Abpa-cre)1Cmal/Tg(Abpa-cre)1Cmal involves: 129X1/SvJ * C57BL/6 * DBA/2	abnormal testis morphology	J:157337
	arrest of spermatogenesis	J:157337
	decreased testis weight	J:157337
	small seminiferous tubules	J:157337
Artm1Jdz/Y Tg(CMV-cre)1Cgn/0 involves: 129X1/SvJ * BALB/cJ	decreased testis weight	J:157337
Artm1Jdz/Y Tg(Pbsn-cre)20Fwan/? involves: 129X1/SvJ * C57BL/6 * FVB/NCrl	abnormal prostate gland anterior lobe morphology	J:122327
	abnormal prostate gland epithelium morphology	J:122327
	abnormal prostate gland morphology	J:122327
	abnormal seminal vesicle epithelium morphology	J:122327
	decreased epididymis weight	J:122327
	decreased prostate gland weight	J:122327
	decreased seminal vesicle weight	J:122327
	normal growth/size/body region phenotype	J:122327
	small prostate gland	J:122327
	small prostate gland anterior lobe	J:122327
	small prostate gland ventral lobe	J:122327
Artm1Jdz/Y Tg(Pbsn-cre)20Fwan/? involves: 129X1/SvJ * C57BL/6J * FVB/NCrl	abnormal cauda epididymis morphology	J:137429
	abnormal copulatory plug biosynthesis	J:137429
	abnormal corpus epididymis morphology	J:137429
	abnormal seminal vesicle epithelium morphology	J:137429
	abnormal seminal vesicle morphology	J:137429
	abnormal seminal vesicle muscle layer morphology	J:137429
	abnormal sperm flagellum morphology	J:137429
	abnormal sperm number	J:137429
	coiled sperm flagellum	J:137429
	decreased copulatory plug deposition	J:137429
	decreased litter size	J:137429
	decreased seminal vesicle weight	J:137429
	hairpin sperm flagellum	J:137429
	impaired fertilization	J:137429
	kinked sperm flagellum	J:137429
	premature acrosome reaction	J:137429
	reduced male fertility	J:137429
	normal reproductive system phenotype	J:137429
	small seminal vesicle	J:137429
Artm1Rax/Y involves: 129S/SvEv * C57BL/6J	no abnormal phenotype detected	J:147485
Artm1Rax/Artm1Rax involves: 129S/SvEv * C57BL/6J	no abnormal phenotype detected	J:147485
Artm1Reb/Y involves: 129S4/SvJaeSor	abnormal seminiferous tubule morphology	J:90393
	abnormal testis morphology	J:90393
	normal behavior/neurological phenotype	J:90393
	decreased seminal vesicle weight	J:90393
	decreased testis weight	J:90393
	increased circulating follicle stimulating hormone level	J:90393
	increased circulating luteinizing hormone level	J:90393
	increased circulating pituitary hormone level	J:90393
	increased circulating testosterone level	J:90393
	oligozoospermia	J:90393
Artm1Reb/Y Tg(Amh-cre)8815Reb/? involves: 129S4/SvJaeSor * FVB/N	abnormal seminiferous tubule morphology	J:90393
	abnormal Sertoli cell barrier function	J:210656
	abnormal testis morphology	J:90393
	azoospermia	J:90393
	decreased seminal vesicle weight	J:90393
	decreased testis weight	J:90393
	increased circulating follicle stimulating hormone level	J:90393
	increased circulating luteinizing hormone level	J:90393
	increased circulating pituitary hormone level	J:90393
	increased circulating testosterone level	J:90393
Artm1Ska/Y Tg(CMV-cre)1Ipc/? involves: C57BL/6 * CBA	abnormal body weight	J:85484
	abnormal heart left ventricle morphology	J:101049
	abnormal myocardial fiber morphology	J:101049
	abnormal penis morphology	J:85484
	abnormal reproductive system physiology	J:85484
	absent epididymis	J:85484
	absent prostate gland	J:85484
	absent seminal vesicle	J:85484
	absent vas deferens	J:85484
	arrest of spermatogenesis	J:85484
	blind vagina	J:85484
	cardiac interstitial fibrosis	J:101049
	cryptorchism	J:85484
	decreased heart left ventricle wall thickness	J:101049
	decreased heart weight	J:101049
	decreased myocardial fiber size	J:101049
	decreased ventricle muscle contractility	J:101049
	increased white adipose tissue amount	J:85484
	obese	J:85484
	postnatal growth retardation	J:85484
	secondary sex reversal	J:85484
	small heart	J:101049
	testis degeneration	J:85484
Artm1Verh/Y involves: 129S1/Sv * 129X1/SvJ	normal reproductive system phenotype	J:88169
Artm1Verh/Y Plekha5Tg(AMH-cre)1Flor/Plekha5+ involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6	abnormal Leydig cell morphology	J:100799
	abnormal spermatid morphology	J:88169
	abnormal spermatocyte morphology	J:88169
	arrest of male meiosis	J:88169
	arrest of spermatogenesis	J:88169
	azoospermia	J:88169
	decreased epididymis weight	J:88169
	decreased Leydig cell number	J:100799
	decreased male germ cell number	J:88169
	decreased testis weight	J:88169, J:100799
	normal growth/size/body region phenotype	J:88169
	increased circulating follicle stimulating hormone level	J:88169
	increased male germ cell apoptosis	J:88169
	small seminiferous tubules	J:88169
	small testis	J:88169
Artm1Verh/Y Rnase10tm1(cre)Hht/Rnase10+ involves: 129S7/SvEvBrd * C57BL/6	abnormal caput epididymis morphology	J:173897
	abnormal epididymis epithelium morphology	J:173897
	abnormal epididymis morphology	J:173897
	abnormal male genitalia morphology	J:173897
	abnormal male reproductive system physiology	J:173897
	abnormal testis morphology	J:173897
	enlarged testis	J:173897
	epididymis epithelium degeneration	J:173897
	male infertility	J:173897
	seminiferous tubule degeneration	J:173897
	testicular atrophy	J:173897
	testis inflammation	J:173897
Artm1Verh/Y Tg(Fabp4-cre)1Rev/0 involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal adipose tissue amount	J:196857
	decreased gonadal fat pad weight	J:196857
	decreased susceptibility to weight gain	J:196857
	hyperglycemia	J:196857
	impaired glucose tolerance	J:196857
	increased brown adipose tissue amount	J:196857
	increased circulating insulin level	J:196857
	increased circulating triglyceride level	J:196857
	increased interscapular fat pad weight	J:196857
	increased mesenteric fat pad weight	J:196857
	increased omental fat pad weight	J:196857
	insulin resistance	J:196857
Artm2.1Reb/Ar+ Tg(Amh-cre)8815Reb/? 129S(FVB)-Artm2.1Reb	abnormal Sertoli cell barrier function	J:210656
	abnormal Sertoli cell barrier morphology	J:210656
Artm2Ska/Y Gli1tm3(cre/ERT2)Alj/Gli1+ involves: 129S6/SvEvTac * C57BL/6 * CBA	abnormal external male genitalia morphology	J:148515
	abnormal foreskin morphology	J:148515
	abnormal reproductive system development	J:148515
Artm2Ska/Y Shhtm2(cre/ERT2)Cjt/Shh+ involves: 129S6/SvEvTac * C57BL/6 * CBA	normal reproductive system phenotype	J:148515
Artm2Ska/Y Tg(KRT5-cre)1Tak/0 involves: C3H * C57BL/6 * CBA	normal reproductive system phenotype	J:148515